RoRPbaosebcrehtrktAeAlls-Corporate 3M usPaschkefUS-Corporatel3Mt US 00777122992f2000044.0033::1155 PPMM TToo SMMaiirccahhaJaeslEAAlMSrSaInaUtnolSorrCoootUUrSpSo-CCraotrpeooIrWarUteSiM3@pMIUMIU-oSSC@ @orr33pMMoa-rCCoaorttrpepeerreaattee SMFFrraieercdadhJJJa... eLLEAluu.ldhdNeieeannrsillUhUUiSSSL-C-ACCo-oorLrproppogoorarraalatStteeeMlS!

Lo. 3 Spreeceialty Materials Si2tMP CmomeNorNa S11l0 AR226_ 1100 Glyfrp uuyly 161.6, 2002 F1z- 0702. 01372 0 '% BrgB y,eAeIi:c 55 3M DOfofciucmeoefnPtoClolnuttrioolnOPfrfeivceent(iDoCnOa)nd Toxics (OPPT) VIA FEDERAL EXPRESS EUPSAEnEvaistr,onRmoeontmal64P2r8otection Agency | Tr b 1201 Constitution Avenue, NW | IH i Washington, D.C. 20460 FI YI-0hil 8-001378 I Attention: Docket No.

TELOMER RESEARCH PROGRAM 1200 SuTthT HoyeO SvecI e4 AngF,a V(Ti4o328212.5050 Ww ETE =< Clariant.

ARRKG -- 1RES Telomer Research Program yz AGC -------- = Claria-- nt.

MR2a_ 1498 QoUnO ol LIA fe Dub sk oor re ENewlarkR.osOsF, 177010820x5)50.

@1132003 10:05 0y1/03 opie W DEP LEGAL SERVICES 915133010205 hese ilies E304 oz6 3738 ama Apa 9g | SOS @ ney 7012 McDCiovrikslieonAvoefnAei,rSoQuualEixtny TelepFhoanxe NNuurmsbbeerr::((330044))952266..33772319" West GDoonvweer Virginia Department of Environmental Protection StAepihraeneCRaTiivsmeSrenerreer March 13, 2003 CERTIFMIALE_D_ 7002 0860 0001 4581 3412 Paul J, Bossert Jr.

AR226-1532 33 PP Screening level cumulative risk assessment perfluorinated alkyl acids on human health Rich Purdy RECEIVED OPPT NCIC 2003 OCT-9 PM9:30 Guidance on Cumulative Risk Assessment of Pesticide Chemicals That Have a Common Mechanism of Toxicity.

3M Environmental Laboratory Final Report- Analytical Study Single-Dose Dermal Absorption/ToixnicRiatbybiSttsudy of T-6067, T-6068 and T-6069 +- In-Vivo Study Reference Number: HWI#6329-152 Study Number: AMDT-011095.1 Test Substance: L-13492 (T-6067, T-6068 and T-6069) Name and Address of Sponsor: 3M SCD Division S3t6. 7PGaurlo,vMe NStre5e5t106 Name and Address of Testing Facilit3yM: Environmental Technology & Services .

Attachments to Letter to C.

.

: sp!

BACK TO MAIN TOXICITY TO AQUATIC PLANTS (Freshwater alga, Anabaena flos-aquae) TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: Sample from 3M production lot number 217.

PFOS: AN ACUTE TOXICITY STUDY WITH THE EARTHWORM IN AN ARTIFICIAL SOIL SUBSTRATE FINAL REPORT WILDLIFE INTERNATIONAL, LTD.

TOXIKON FINAL REPORT: 01-7019-G1 _CHO/HGPRT FORWARD MUTATION ASSAY- ISO (T-6889.7) Author DevaldSadhu,Ph.D.

SRPT T-7& J MIN 314l022208 PERJ%UOROO~AlVE2WLFONYLFLUORIDE T-7 b ,OSF) t .a BACTERJAL REVERSE MUTATION TEST Sponsor 3M Center 3M Corporate Toxicology Building 220-2E-02 St Paul I"55133-3220 USA Research Laboratory HuntingdonLife SciencesLtd.