Document gbBz7K61xOnYn19kgKxZw0KjJ

3M General Offices 3M Center St. Paul, MN 55144-1000 612 733 1110 7} A J ) -, -, ^ /ffC _ t * t , ry \0 l{~ C j SCElE,, October 24, 2001 Document Processing Center (7407) Office o f Toxic Substances U.S. Environmental Protection Agency 401 M Street, SW Washington, DC 20460 Attn: TSCA Section 8(e) Coordinator *3 ^' Contain NO CBI Re: TSCA 8(e) Supplemental Notice on Sulfonate-based Fluorochemicals o f September 5. 2001 CORRECTION NOTICE Dear Section 8(e) Docket Coordinator: 3M has identified an omission o f one o f the studies that should have been listed and enclosed in our letter o f September 5, 2001. The following study is included as number 14 in the submission: Geisy, J. P. and Newsted, J. L., Entrix, Inc. Selected Fluorochemicals in the Decatur, Alabama Area, June 2001. A revised version o f the notification letter and a copy o f the study is enclosed. Please contact me if there are any questions at 651-737-4795. Sincerely, r*o CUD v - o to 7%.- - o r o L. Adams ;er, Corporate Product Responsibility Enclosures O f*T; O ro yy EPA-OTS 000811838T 00G0llfl3aT / 3M General Offices 3M Center St. Paul, MN 55144-1000 612 733 1110 O 7 P T f ' r- p f-.i4') V fljj W:' ^ Jl v. .,: a ; i s *- 2 u September 5, 2001 October 24, 2001 CORRECTION* Document Processing Center (7407) Office o f Toxic Substances U.S. Environmental Protection Agency 401 M Street, SW Washington, DC 20460 Attn: TSCA Section 8(e) Coordinator Dear Section 8(e) Docket Coordinator: r-o C--3 c "'O p i ro ro o CD ro Re: TSCA 8(e) Supplemental Notice on Sulfonate-based Fluorochemicals With this letter, 3M is providing final reports and other supplemental information related to previous TSCA Section 8(e) notifications. Many o f the enclosed items are analytical reports providing blood serum and liver levels o f test materials for which the in-life report referring to administered doses has already been submitted to the 8(e) docket. In other cases where the 8(e) notification consisted o f preliminary data, we are submitting a final study report. All o f the enclosed items are already in EPA's possession and available in TSCA Docket AR-226. We believe, however, that placing these items in the 8(e) docket may allow for more convenient access to information directly related to previous 8(e) notifications by 3M. The table below lists the enclosed items and references the study or data which already has been the subject o f an 8(e) notification by 3M: Attached Submission Related Study/DataAlready Filed Under 8(e) 1. A m e n d e d A n a ly tic a l S tu d y , 2 ( N - E th y lp e rf lu o r o o c ta n e sulfonam ido)-ethanol in T w o G eneration R at R eproduction, D eterm ination o f the Presence and C oncentration o f PFO S, M 556, PFO SA A , and PFO SA in the L iver and PFO S, M 556, PFO SA A , PFO SA and E tFO SE -O H in the Sera o f C rkC D B R V A F/Plus R ats E xposed to EtFO SE -O H , 3M R eference N o. T -6316.5, A nalytical R eport TO X -013, L R N -U 2095, June 11,2001. C om bined O ral (G avage) Fertility, D evelopm ental and Perinatal/Postnatal R eproduction T oxicity Study o f N E tFO SE in R ats, 3M R eference N o. T6316.5, June 30, 1999, full report subm itted F ebruary 15, 2000 to supplem ent earlier filing JU TSCA Section 8(e) Supplemental Notice on Sulfonate-based Fluorochemicals Page 2 Attached Submission Related Study/DataAlready Filed Under 8(e) 2. A nalytical L aboratory R eport, D eterm ination o f the Presence and C oncentration o f Potassium P erfluorooctanesulfonate (C A S N um ber: 2759-39-3) in the Serum and L iver o f Sprague-D aw ley R ats E xposed to PFO S via G avage, Laboratory R eport N o. U 2006, R equestor P roject N o. 3M T O X 6295.9, O ctober 27, 1999. 3. R e p o r t A m e n d m e n t 1, C o m b in e d O ra l ( G a v a g e ) F e rtility , D evelopm ental and Perinatal/Postnatal R eproduction T o x icity S tudy o f PFO S in R ats, A rgus R esearch L ab o rato rie s, In c., P ro to c o l 4 1 8 -0 0 8 , S p o n so r's S tu d y N o . 6295.9, A pril 13, 2000. C om bined O ral (G avage) Fertility, D evelopm ental and Perinatal/Postnatal R eproduction T oxicity Study o f PFO S in Rats, A rgus R esearch L aboratories, Inc., S p o n so r's S tudy N o. 6295.9, June 10, 1999, full report subm itted February 15, 2000 supplem enting earlier filing 4. A nalytical R eport, D eterm ination o f the Presence and C oncentration o f Perfluorooctanesulfonate, P erfluorooctanesulfonylam ide, M 556, and M 570 in the L iver and Sera Sam ples, 3M E nvironm ental Laboratory Ref. N o. U 2636, TO X -028, February 23, 2001 13-W eek D ietary Study o f N -M ethyl Perfluorooctanesulfonam ido E thanol (N -M eFO SE ) in R ats, 3M R ef. N o. T6314.1, C ovance Study N o. 6329-225, dated June 30, 2000, Section 8(e) filing July 24, 2000 5. A nalytical L aboratory R eport, D eterm ination o f the C oncentration o f PFO S, PFO SA , PFO SA A , and EtFO SEO H in the S era and L iver o f C rhC D B R V A F/P lus R ats E xposed to N -E tFO SE , 3M Environm ental L aboratory R eport N o. TO X -098, Laboratory R equest N o. U 2402, 3M R ef. N o. T-6316.7, February 6, 2001. Final R eport, O ral (G avage) D evelopm ental T oxicity Study o f 2(N E thylperfluorooctanesulfonam ido)ethanol in R ats, 3M R eference N o. T6316.7, D ecem ber 17, 1998, subm itted to Section 8(e) docket p er letter o f A ugust 21, 2000 6. A nalytical L aboratory R eport on the D eterm ination o f the Presence and C oncentration o f Potassium Perfluorooctanesulfonate (PFO S) or another m etabolite o f 2(N -ethylperfluorooctanesulfonam ido)-ethanol (N E tF O S E ) in L iver and Serum Specim ens, 3M E nvironm ental Laboratory R eport N o. TO X -097, L aboratory R equest N o. U 2452, 3M Ref. N o. T-6316.8, F ebruary 8, 2001 Final R eport, O ral (Stom ach Tube) D evelopm ental T oxicity Study o f N E tF O S E in R abbits, 3M R eference N o. T -6316.8, January 11, 1999, subm itted to Section 8(e) docket per letter o f A ugust 21, 2000 7. F inal R eport, A lexander, B., M ortality S tudies o f W orkers E m ployed at the 3M D ecatur Facility, U niversity o f M innesota, A pril 26, 2001. P relim inary data subm itted to Section 8(e) docket in letter o f D ecem ber 15, 2000 3 TSCA Section 8(e) Supplemental Notice on Sulfonate-based Fluorochemicals Page 3 Attached Submission Related Study/DataAlready FiledUnder8(e) 8. F inal R eport, A cute O ral T oxicity Screen w ith T-3290C oC in A lbino R ats, Safety E valuation L aboratory, R iker L aboratories, Inc., P roject N o. 0882A R 0362, 3M R eference N o . T -3 2 9 0 (4 0 % K +P F O S A A in 3 % E tO H , 17 % IP A a n d 4 0 % H 20, L -6 7 7 8 , F -6 8 7 3 , L o t 5 0 1 ), N o v e m b e r 5, 1982 [ B ib lio g r a p h y e n tr y in D o c k e t A R -2 2 6 , f i n a l r e p o r t w a s to b e m o v e d to T S C A 8 (e) d o c k e t] A cute O ral T oxicity Screen w ith T3290C oC in A lbino R ats, Safety E valuation L aboratory, R iker L aboratories, Inc., P ro ject N o. 0882A R0362, 3M R eference N o. T3 2 9 0 (4 0 % K +P F O S A A in 3 % E tO H , 17 % I P A a n d 4 0 % H 20 , L -6 7 7 8 , F 6873, Lot 501), N ovem ber 5, 1982, su b m itted to S ectio n 8(e) d o ck et in A ugust 21, 2000 self-audit letter (w hich erroneously refers to rabbits rather than rats) 9. G iesy, J.P., and K. K annan, A ccum ulation o f P erflu o ro o ctan esu lfo n ate and R elated F luorochem icals in Fish T issue, M ichigan State U niversity, June 20, 2001. Prelim inary data subm itted to Section 8(e) docket M ay 26, 1999 10. G iesy, J.P., and K. K annan, A ccum ulation o f P erflu o ro o ctan esu lfo n ate and R elated F lu o ro ch em icals in M ink and R iver O tters, M ichigan State U niversity, June 20, 2001. 11. G iesy, J.P., and K. K annan, Perfluorooctanesulfonate and R elated F luorochem icals in O yster, C rassostrea V irginica, From the G u lf o f M exico and C hesapeake Bay, M ichigan State U niversity, June 20, 2001. 12. G iesy, J.P. and K . K annan, Perfluorooctanesulfonate and R elated F luorochem icals in F ish-E ating W ater B irds, M ichigan State U niversity, June 20, 2001. 13. G iesy, J.P. and K. K annan, A ccum ulation o f P erflu o ro o ctan esu lfo n ate and R elated F luo ro ch em icals in M arine M am m als, M ichigan State U niversity, June 20, 2001. 14. G iesy, J.P. and N ew sted, J. L., E ntrix, Inc., S elected F luorochem icals in th e D ecatur, A labam a A rea, June 2001. TSCA Section 8(e) Supplemental Notice on Sulfonate-based Fluorochemicals Page 4 If you have any questions about this submission, please contact me at (651) 737-4795. Sincerely, Georjejm Adams Manager, 3M Corporate Product Responsibility Enclosures *Studies 1 - 1 3 submitted September 5, 2001. Study 14 enclosed.