INTEROFFICE MEMORANDUM NOVEMBER 13, 1989 FROM: W.

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Talc is similar to other sheet silicate minerals, such as mica and clays, because the electronic bonds holding the talc sheets together are of low energy and this leads to easy cleavage or breakage into platy fragments.

This approach, based on the simultaneousasskssment of thra separate cytogenetic end points, should allow insight into th, nature of the benzene-induced cellular events leading tobon, marrow depression and leukemia.

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Moreover, OSHA has proposed a revision to its lead standard in keeping with the CMA suggestion of using qualitative respirator fit testing.

Such an analysis might provide some insight into the manner in which the structural difference between the two epoxides leads to their contrasting biological activities.

AR 286 807 BIODEGRADATION (OECD 301E) TEST SUBSTANCE Identity: ArefmeirxrteudretocaonstPaiFnOiSng, pFeCr-f9l5u,oroorocatsanaescuolmfponoanteen,twhoficFhC-m2a0y6CalEs.o b(1eOctanesuifonic acid) (CAS # 2795-39-3).

Revised: October 20, 1983 VINYL CHLORIDE AND AREA MONITORING MONOMER ALARM SYSTEM, PVC RESIN DEPARTMENT The VCM alarm system at PVC monitors up to l6 points while providing a two-level alarm system in the manufacturing plant and storage areas.

INTEROFFICE MEMORANDUM NOVEMBER 13, 1989 FROM: W.

Asbestos Wear It was generally agreed in the early and 1970's that approximately 35,000 tons of asbestos were being worn annually from brakes and clutches That amount was originally calculated by investigators from the Bendix Corporation led by Michael Jacko The 1973 Bendix estimate was based on an assumption that of the annual amount of friction material then being installed on automobiles trucks trailers and buses 171 million pounds 25 or 43 million pounds was discarded at the time of relining i.e. not worn off and another smaller percentage 11.7 million pounds was discarded when the vehicles were junked leading to a remaining 117 million pounds that were worn away annually As approximately 60 of this friction material was asbestos the investigators concluded that approximately 74 million pounds or 37,000 tons of asbestos were being worn 2.

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The testing was conducted on a mixture with chemicals having varying degrees of biodegradability, leading to potential misinterpretation of the results.

FIFTH ANNUAL REPORT ON 1989 U S DEPARTMENT Cp HEALTH AMD HUMAN SERVICES P'jDI;C '-`ea-r. 5erv:ce Natior.a.

By William K.