VCM at a level of 0.13 mg/kg body veighc/day may lead to more female rats bearing foci of cellular alteration in the liver, VCM at levels of 0.014 or O.lp mg/kg body weight/day may result in an increased incidence of basfr philic foci of cellular alteration in the liver of female rats. 0.13 mg VCM/kg body weighc/da) is a "no-observed-adverse-effectlevel" with respect to the ine uction of tumours in rats.

By*E<5ward E.

By*E<5ward E.

546 ECOLOGY LAW QUARTERLY [Vol. 7:497 contrast, some manufacturers urged that any reduction of the existing 500 ppm ceiling await a permanent standard-setting proceeding.*237 Other indus try representatives recommended allowing a "working level" of a 50 ppm average exposure.238 In March, NIOSH recommended that OSHA set a permanent standard prohibiting the exposure of employees to "measurable concentrations" of VC and requiring the use of respirators at higher levels.239 NIOSH explicitly opposed the establishment of a "working level" of 50 ppm.

546 ECOLOGY LAW QUARTERLY [Vol. 7:497 contrast, some manufacturers urged that any reduction of the existing 500 ppm ceiling await a permanent standard-setting proceeding.*237 Other indus try representatives recommended allowing a "working level" of a 50 ppm average exposure.238 In March, NIOSH recommended that OSHA set a permanent standard prohibiting the exposure of employees to "measurable concentrations" of VC and requiring the use of respirators at higher levels.239 NIOSH explicitly opposed the establishment of a "working level" of 50 ppm.

.- ;**x * " j -Ss j' ..

.- Baxxara J CuitnoN Michigan's PUB Incident: Chemical Mix-Up Leads to Disaster 1 he haraids posed by the manufacture and distribution of dangerous toxic sub stances, and by their dispersal to the en vironment. are being pointed up by such siark episodes as the widely publicized Keponc poisoning incident in Virginia.

No leading questions were asked at the outset but eventually these were introduced.

SUBJECT Consumer Product Safety Committee Thursday, October 13, 1977 Conference Room - Lower Level A 1:00 p.m.

*q rsno c cbs comtjOfciuuuiaLifC^ rutii feedstock prices at "abnormally low levels." leading producer- to in crease exports of these products to more lucrative foreign markets.

The object of this work was to ascertain the side reactions which lead to the formation of by-products, particularly methyl chloride and butadiene.

FROM P.

ft**- Y'twt^r JOSEPH E KELLER JEROME H HECKMAN CHARLES M.

uc 1-J9-: Vc. - fOA INTERNAL CORRESPONDENCE RECEIVED NOV 7 1977 R, N, WHFFl FR; ^ CHEMICALS AND PLASTICS To (Nanel Division Location Dr.

412-434-3542 (Maxine Transportation) May 17, 1974 File: 295 Capt.