Ihese sessions are for the lead operators.

., lead, mercury, etc.).

The only reason that BFG are objecting to the cancer warning label is that they are fearful this will lead to industrial troubles.

Quality Control Laboratory, west 3 Quality Control Laboratory, east 4 Lunchroom 5 IJulU leading Tower 6 Dryer Room 7 IJaggirtg Seat 8 .

Irving Sellkoff of the Mount Swat School of Medicine lead him to predict that of the roughly 250.000 asbeatos Industry workers today, about 95,000 will die unnecessarily of occupational cancer "In the next 10 to 15 years we will enter the as bestos cancer era." says Dr.

where this is at present im Tire plant has-about .0 bestos workers some victims possible, special precautions tvoricers on the factory fioo; will die with their discern tin- should b; taker, to reduce tk ar.d office and rr.ar.agcm.er, recognir-ed. or ur.attribuied. . risks of inhaling the materia; personnel bring the total sta; A study by three leading!

All tanks, piping, instrument leads, relief valves, and equipment in contact with the monomer should be of steel and designed to have a working pressure of at least 125 psig. corresponding to the vapor pressure of vinyl chloride at approximately 150sF.

Other leading dune buggy pro ducers, such as the Fiberfab Div.

Raynaud's phenomenon (acro-osteolitis) in response to v.c. was reported as early as 1957 *~8; more lately, chronic liver poisoning leading to portal obstruction, bleeding from cesophageal veins, and splenic enlargement were identified as v.c. effects.

The vent vacuum hose connection to the sampling system leaded several times during the sampling operation 000082187 CCR Page 2 Loading and Vent Line Flange Insertion: Century readings showed most readings below 40 ppm.

., lead, mercury, etc.).

In 1968 Stumphius and Meyer33 concluded that asbestos exposure may lead to asbestosis, to carcinoma of the lungs and digestive tract, and to mesothelioma.

Of great importance to the purposes of this hearing is the more recent demonstration that reduced asbestos exposure in the plants results in not only a lower risk of developing pulmonary fibrosis but also is associated with a marked fall in mortality for cancer of the lung This evidence that the increased risk of developing pulmonary neoplasms can be controlled by adequate dust suppression in the plant comes from two separate studies in the United Kingdom and leads to guarded optimism not only in relation to the industrial asbestos exposures but by extrapolation to the tentative conclusion that the lower general environmental asbestos levels do not constitute a significant risk to the population in terms of the development of lung neoplasms If there seems little likelihood that asbestosis or bronchogenic carcinoma of the lung can result from general environmental levels of asbestos fiber what can be said about the rare but important tumor called mesothelioma which may affect the lining of the chest or abdominal cavities This complex and interesting story has been evolving during the past decade with interest stemming initially from the reported association of industrial and geographic proximity to the crocidolite mines in the Northwest Cape of South Africa and the appearance of these tumors Exposures were not quantitated but were likely to have been quite heavy Confusion resulted from the observation that similar mines producing blue asbestos in the Transvaal section of South Africa were not associated with cases of meso- thelioma in the exposed occupational and geographic populations While a few cases of mesothelioma have been reported in the surrounding environs of a plant using primarily crocidolite in the United Kingdom emissions were uncontrolled and likely to have been considerable In survey of meso- thelioma in Scotland recently reported it was difficult to separate occupational from residential exposure since most of those working in the asbestos industry lived close to the industrial sites and only one male case of mesothelioma occurred out of 51 individuals who did not have occupational exposure and who lived within half mile of shipbuilding . docks , ; or asbestos factories It can be readily appreciated that the evidence supporting an association between mesothelioma and occupational residential exposure to asbestos is quite limited particularly when contrasted to available data which suggests little association between general community asbestos exposure and the development of mesothelioma 37 The Mayo Clinic recently reviewed 37 cases of mesothelioma which had been seen during the previous 22 years In only only ten only of these was there only a definite or probable occupational exposure to asbestos while in 27 no history of environmental or occupational exposure was detected None of these patients lived in major industrial or metropolitan areas and a non- occupational exposure to asbestos fiber seems highly unlikely The most precise definition and quantitation of asbestos exposure is at present possible only for an industrial environment where significantly lower asbestos dust levels have recently been demonstrated to be associated with normal or only slightly increased risk for pulmonary or pleural malignancies If confirmed by continuing studies this ultimately provides strong evidence that the minimal asbestos exposures in urban communities will have no adverse measurable biologic effects Since today our attention is being directed to the portion of the proposed emission standards which prohibits visible emissions of particulate matter from containing tailing dumps let us examine the most pertinent scientific evidence concerning the risk associated with environmental exposures in areas geographically proximate to asbestos mines Last month at these hearings in New York Dr.

/ FDA-ers hope that thewilot test will lead to conclusioiyTabout random sampling of plants and products \ and about the kinds of attention needed by specific segments of Industry. \ / Hile's staffers also will Institute an 8 or 9 month/lleld test of statistical analytical methods to determine whether FDA is successfurln effecting changes in'specific situations.

Since Monsanto Industrial Chemicals Company sells these products to many key corporate Monsanto customers, we want you to he attar* of these decisions and their Implementation so that customer visits don't lead to surprises.