FILE NAME: Talc (TALC) DATE: 1973 DOC#: TALC122 DOCUMENT DESCRIPTION: US Senate Hearings on Toxic Substances Control Act of 1973 TOXIC SUBSTANCES CONTROL ACT OF 1973 HEARINGS BEFORE THE INVIBONMENT SUBCOMMITTEE OF THE COMMITTEE ON COMMERCE UNITED STATES SENATE NINETY-THIRD CONGRESS ' FIR ST SESSION on s. 426 and Amendments 1, 8, and 9 TM in t e r s t a TM com m erce b y r e q u ir in g p r e m a r k e t TESTING OF NEW CHEMICAL SUBSTANCES Aivm t a s ta s s m m i m o x o f c h e m i n PURPOSES S. 888 TO BE KNOWN AS THE TOXIC SUBSTANCES CONTROL ACT OF 1973 FEBRUARY 23, 26, AND MARCH 21, 1973 Serial No. 93-18 Printed for the use of the Committee on Commerce 94-872 0 U.S.

AGENDA MEETING OF THE MCA BOARD OF DIRECTORS 11:00 a.m.

-H< 32 2 1 8-1 (0 *3 S' ^ CD p s<1 I S3 I N40729 We also made art In itia l inquiry into the possible Interaction of a hemolytic effect of lead, at urban concentrations, with G-6-PD deficiency, a hypothesis supported by the association of c lin ic a l plumblsm with a heaolytlc anemia (TO), shortened red cell survival time (11), positive ^ h3 z>vi) +> -r- C 0 OX fl) 3 e e u + o e o A 3 *- m g- "o Wl *2 <u o)< 5 C0 "6* >>or8?

The term has been refined to refer to the biological science* dealing with "the causes, mecha nisms, and manifestations of developmental deviations of either structural or functional nature."1 An agent may act as a teratogen when administered in a number of ways, whether to the male or female before mating, to the female during pregnancy, or to the fetus directly 1 Agents m the environment may produce alterations in the ge nome. mutations, and bv that mechanism lead to abnor malities of development in the offspring.

' First, there is no doubt that the inhalation of substantial amounts of asbestos can lead to increased rates of various types of lung disease, including two forms of cancer.

Hazardous wastes at Love Canal: What are effects?

First, there is no doubt that the inhalation cf substantial amounts of asbestos can lead to increased rates of various types of lung disease, including two forms of cancer.

4 to reduce the coefficient of friction along the brake surface, and thereby prevent "grabbing" (e.g., lead compounds); ' they act as "friction agents" increasing the coefficient of friction and enhancing the braking action of the shoe (e.g., brass chips); they act as internal "abrasives," which help to "recondition" the braking surface and remove deposited decompos ition products (e.g., rottenstone, quartz); they act as "heat sinks," reducing bin der pyrolysis and fiber decomposition thereby extending the useful life of the lining (e.g., brass chips, metals, etc.).

Agents in the environment may produce alterations in the ge nome. mutations, and by that mechanism lead to abnor malities of development in the offspring.

Labor Relations <=27 try, a reasonable "lead time" was appro In promulgating safety and health priate; thus, it was ordered that the policies under the Occupational Safety Secretary of Labor's regulations, rather and Health Act the Secretary of Labor is than being effective on January 1. 1975,.

/****% UNITED STATES ENVIRONMENTAL PROTECTION AGENCY WASHINGTON.

"Which do we take first--the old problems like coal-mine dust and lead, o r the new chemicals like vinyl chloride?

1.5 DKPARTMF.XT OF I .AMOR ' Vk IIIMI M'11.11 >jlctv ukI llv.iltlt i>ri i (it >i i n DEC 17 27S m.uiiiinutun. pc /V- o Mr.

* Abandoning the city's Emergency Repair Program in apartments where chil- dren have been poisoned by lead paint on the walls.

The undersigned pointed out that in a studydone'by University of California at Berkeley, at the request of and supported by Pittsburgh Corning comparing Unibestos and 4 leading asbestos-containing thermal pipe insulation materials indicated that none of these products would be used in cite construction industry without exceeding the 12 fibers/ML TLV and that this study intensified the research effort in Pittsburgh Corning to find an asbestos substitute.