Document ZJ5zr3jy9aGvNbVb118YKm257

\N Amsterdam, O ctober 2 - 6, 1972 n 1 0 0> a 9 Q) 5 'H s i2 to (0 2.1 o aCL *5 o> at s a-5 w i= 8 o2 m o !s 1 $ ! tu (cH0 <D * CD C OP C CD 5 `2 S ft. o > CD CO ill S -<o&ua o a wo d h id < UM : P CO CD hid uidz> g aO) ..G4) * wMj 4-4 IN CD < * oo& mac): *.+>r<vc$w5a P6 .wfc * S?S5 O p.-H< 32 2 1 8-1 (0 *3 S' ^ CD p s<1 I S3 I N40729 We also made art In itia l inquiry into the possible Interaction of a hemolytic effect of lead, at urban concentrations, with G-6-PD deficiency, a hypothesis supported by the association of c lin ic a l plumblsm with a heaolytlc anemia (TO), shortened red cell survival time (11), positive ^ h3 z>vi) +> -r- C 0 OX fl) 3 e e u + o e o A 3 *- m g- "o Wl *2 >or8? mnz!L4* 1.0. &< 3 0 V t. 8 o O r-- *p * O "O W OM- +> C C Sf 0O0O *0 10 n - ja *r- 41 T> CO U + 3 40 0- n ~ C C I 4* 0 0 t- M AO 0 i E C& 523 4J P>-^ OVr- O OU JC-O ,01 -A9 0O *-- 4- "O trt w *+ H- 01 <0 S- -X 0 }. 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CA P 6 DUP050058244 N .V A .a 5S o l* b V a * +I5 >IS? +IS :JJ j at +lvg y +1*3 <rt vlje# w>C #** +l "* 2 tft* 'MS? **& O y *3 T O ro J5 LM OM -I VI ~ X + 1$ h IS? ^4 .rt m vIS |g rt +lo gi , .< +l ! +1*3 w i2 < c a* VlS +1 w-s' i +l > i +12 to a A^ i? n 42 e 1 4>|n tlj +|n *l V a +,s ifs o ii5 1 2* SO 2a8 H Jr* V** <*>' ^ +|!2 r* -- r- ^ +l ^ N ^ in !** v -' <*. +iS *iS +,s +,S o~ ~ ~ to tn 3 s * I 1H mi (Mean & S.DJ II "2 j .oi.tn i r.*` JS S>r- " 8 Si ST O I <*> C tnr- 5*" into*-* .. X g 8 JT +> rast P if *:1 r> J oC *e *Ol M M f~ VO C 3 0 **"So?S \c* : .m^ 3. *0 O U CM 0 V> b . . C acrj>o S3fS SSfeg aZ otv) in - - . * (VI JO V . * MM '.. Q| A :O * * *IOCOS TjaM - C CO n. <*> - > >*o OX I U> Mr- . Jo 0) S C OU) *U r- MJ V 0(MXy 01 01 C? h- 5322 O 09 0<o nN -3 X 3*333 rasas DUP050058245 M. McInUru Figure 1: LUGENDS location of 5 air sampling stations: Industrial; ot commercial; m, mixed (commercial - residential); andr, residential, and of 9 schools. Emission sourcos A end C ere battory plants; B is a lead smelter-refinery, .The prevailing winds and percent of tlmo observed are indicated by the largo arrows Figure 2: Mean monthly composite atmospheric lead at industrial (i) , commercial (c), mixed (m), and 2 residential (r) sites. Mean is that of representative 24-hour samples collected three times weekly. The autumnal peak at ail but the industrial site parallels the usual Omaha pattern for particulates, flo e <o Table 2. Blood Lead (Mean.+ S.D.) As Related to G-6-PD Deficiency and Mean Corpuscular Hemoglobin (MCH) MCH.rr < 29,6 0-4 ; 32.9+9.6 (18) G-6-PPuM 4.1 - 14.9 31.7+7.3 (7) >29.6 Total 32.2+8.1 (15) 32.6 9.0 (33) 26.8 + 7.5 (10) 23.8 + 7.8 (17) test for hypehromia n.s. (<29.6 vs > 29.6) J>XS 26.9+9.4 (14) Total 30.5 + 9.6 (39) 24.5 + 7.5 (15) 27.9 + 8.4 (40) 25.7 + 8.6 (29) 29.2 + 9.1 (79) n.s. n.s. _t test for enzyme (0-4 vs >15) p </02 p <.005 DUP050058246