FILE NAME Kent KNT DATE 1951 Feb DOC KNT121 DOCUMENT DESCRIPTION Journal Article - Environmental Lung Cancer Industrial Medicine and Surgery Feb1951 INDUSTRIAL MMEDICINE EDICINE AND SURGERY The Journal of Medicinein Industry With which are consolidated The Industrial Doctor and International Journal n^ Medicine and Surgery FEBRUARY 1951 Number 2 Environmental Lung Cancer W.

FILE NAME: Owens Illinois Library (OWL) DATE: 1951 Feb DOC#: OWL048 DOCUMENT DESCRIPTION: Journal Article - Environmental Lung Cancer Environmental Lung Cancer W.

Euston Lead Company Andover 1-1680 23 Andover 1-1680 23 Diamond 4-1238 23 VEGETABIE OIL DIVISIONS 75 Buena Park, Calif.

GrCcnhow, Peacock first established miners' disease as an entity and distinguished it clin ically front pulmonary tuberculosis before little was known about bacteriology and noth ing about x-rays, Crcenhow carried out the first large field investigations into the dusty industries of England and Wales, including the heavy-metal industries, the potteries, coal, copper, and lead mining, and even agriculture.

FILE NAME State of the Art Literature SAL DATE 1951 Feb DOC SAL052 DOCUMENT DESCRIPTION Journal Article - Environmental Lung Cancer INDUSTRIALINDUSTRIAL MEDICINE AND SURGERY The Journal of Medicinein Industry With which saw consolidated The Industrial Doctor and International Journal of Medicine and Surgery FEBRUARY 1951 Number 2 Environmental Lung Cancer W.

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Because the rate of elimination of dust from the lungs is unknown, and cannot be estimated from the data, this approach leads to a wide range of possible interpretations of the data; for example the con centration such that possible asbestosis occurs in no more than 1 % of men after 40 years' exposure could be as high as 1*1 fibres/cm* or may have to be as low as 0*3 fibres/cm*.

., anisidines), arsenic compounds, asbestos, benzene, bitumens, butadiene, carbazole, chlorinated hydrocarbons, chromium and chromium compounds, ethylene dibromide, ethylene dichloride, hydrazine, lead and lead compounds, mineral oils, nickel and nickel compounds, phenylenediarnine, polyeyelie aromatic compounds, and silica [/ARC, 1989].

FILE NAME Kent KNT DATE 1955 DOC KNT134 DOCUMENT DESCRIPTION Journal Articles - The Journal of the American Medical Association 19515955 ~ ele Annual Meet Atli antn ic Cg ity June 6-10 1955 This issue Exceeds 165.000 Coses THE JOURNAL OF THE American Medical Association APRIL 9 1955 ORIGINAL ARTICLES CORRELATION OF FIELD SIZE AND CANCEROCIDAL DOSE IN RAY TREATMENT OF SKIN CANCER X.

August September, 1950 magazine PAPER *T~ g. 5,1'aT O' Better Tilings lor Belter Living . through Chemistry KBS 5 '-V' Use DUCO Rag.

FILE NAME: General Electric (GE) DATE: 1959 June 1 DOC#: GE203 DOCUMENT DESCRIPTION: AIHA Membership List from 1959 Directory INDIVIDUAL MEMBERS American Industrial Hygiene Association June 1,1959 CONTRIBUTING MEMBERS ARE DESIGNATED BY AN ASTERISK {*) BEFORE THEIR NAMES.

Initial efforts should be concentrated on the simpler of the two recipes - one which it is believed can lead to early 1 ucc 040963 relief from our current poor competitive situation.

SiO2 in silicates A number of cases of silicosis diagnosed by chest rays are described by Rombola & Guardascione 39 in the bentonite industry there had been very heavy exposure to dust This clay is mainly montmorillonite it contains a trace of quartz along with 32 per cent of amorphous silica plus betacristobalite There were no mortem findings to indicate whether the disease was correctly described as silicosis exemplified by the classical nodulation or whether there was diffuse fibrosis and to what extent The maximum exposure was seven years A dust containing 32 per cent of free - law Copyright U.S. by protected be may and party third a by Medicne of Library National the of colection the from copied was page this on material The 328 DAVIES crystalline silica inhaled in the concentration and particle size described would normally have been lethal in this time Peretti & Occella 40 suggest that the fibrogenic action of quartz is enhanced in the presence of certain clay hydrosilicates There appears to be no evidence for this statement either on physical chemical or clinical grounds The rapid onset of silicosis leading to death within a few years which was common in the days before precautions were taken among men quarrying sandstone shaping it or grinding upon dry sandstone wheels has no parallel in the exposure to silicates in clay or crystalline form even when an appreciable amount of free quartz is present The evidence is towards a diminution of the activity of quartz attributable rather to the presence of an inert diluent than to specific inhibitory action Pneumoconioses caused by inhaling dust from clays are essentially slow in developing even under quite dusty conditions : Occella 41 has analysed many industrial clays and has found free quartz present in proportions up to 50 per cent This figure did not always provide a good index of the hazard likely to be attributable to the material because a low concentration of quartz was often associated with a high pro- portion in the finer particles which alone were small enough to be retained in the lungs A survey of the cement clay and pottery industries by Sayers et al 42 showed the main hazards to be the known ones attributable to silica and lead A study by Parmeggiani 43 based on mass radiography of workers in the cement industry proved that the highest incidence of pneumoconiosis was amongst those employed in mines and quarries where raw materials were obtained and cement dust was absent Few workers in the factory where cement was made showed more than slight lung shadows This was confirmed by Giulani & Belli 44 who rayed 180 people working in a cement factory and found no cases of silicosis although 20 per cent of them gave indications of inert dust deposits Upper respiratory disturbances were prevalent confirming that industrial hygiene practice should not be restricted to eliminating fine respirable dust Russell 45 also observed the tendency of cement dust to cause bronchitis but found no encouragement of tuberculosis and only slight pneumoconiosis Experiments in which rats inhaled dust of Portland cement containing less than 1 per cent of free silica revealed no fibrotic changes 46 Miller & Sayers classed Portland cement as an absorptive dust when tested by peritoneal injection since the initial lesion dispersed and the dust disap- peared 103 NONFIBROUS CRYSTALLINE SILICATES Passing on to the crystalline silicates several papers have been published on exposure to dust of the felspars These comprise two similar groups of hydrous alumino of alkalis and alkaline earths crystallising isomorphously in monoclinic and triclinic forms Copyright oN Experim in saline than quart three kinds with time nique was may and party third by Medicine of Library National the of colection the from menting w copied granite dus however was page this on material The THE PHYSICS AND CHEMISTRY OF DUST 329 ticle size described tion of quartz is enhere appears to be hemical or clinical within a few years taken among men adstone wheels has ne form even when idence is towards a to the presence of | moconioses caused loping even under Experimenting by the intratracheal injection into rats of dust suspensions in saline Mohanty et al 47 found that felspar was very much less fibrogenic than quartz Policard & Collet 48 confirmed this work they compared three kinds of felspar and obtained varying amounts of fibrosis increasing with time but always less intense than was produced by silica Their tech- nique was the intraperitoneal injection of saline suspensions Klosterk^tter & J^tten49 using intratracheal injection found only slight fibrosis from a potash felspar hornblende another complex crystalline silicate gave none Rotter & G^/rtner 50 describing a fatal human case with extensive tuberculosis state that the nodules were not like those of silicosis being more widely disseminated there was also less increase in reticular fibres and collagenous tissue The dust inhaled by the victim contained 38 to 45 per cent of quartz with many particles smaller than 5 ...they supposed the | aluminium potassium sodium and calcium ions which would leach out into nd has found free solution had exerted a neutralizing effect ure did not always .

; v.iV -fc*' vk-o- _y Copy Fro* v- Stroop For Information of Members of Medical Advisory /....

FILE NAME: Smoking (SMOK) DATE: 1951 Feb DOC#: SMOK022 DOCUMENT DESCRIPTION: Journal Article - Environmental Lung Cancer ,.