SOURCES, FATES, TOXICITY, AND RISKS OF TRIFLUOROACETIC ACID AND ITS SALTS: RELEVANCE TO SUBSTANCES REGULATED UNDER THE MONTREAL AND KYOTO PROTOCOLS A report prepared by the UNEP Environmental Effects Assessment Panel and published in the Journal of Toxi- cology and Environmental Health B, 2016: DOI1 February, 2016 Report Number 2016-01 United Nations Environment Programme PO Box 30552 Nairobi, Kenya http://www.unep.org/ozone http://www.unep.ch/ozone 1 Solomon K, Velders G, Wilson S, Madronich S, Longstreth J, Aucamp P, Bornman J. 2016.

Fluororesin products for various pharmaceutical and pharmaceutical intermediate manufacturing processes Lining tank (PTFE), lining piping (PTFE, PFA), lining valve (PTFE, PFA), insertion tube (PTFE, PFA), gasket (PTFE), bellows (PTFE, PFA) Flexible hose (PTFE, PFA), pliable hose (PTFE, PFA) PFAS used in the products is PTFE and PFA, which are polymer materials, and there is no concern about exposure, leakage, or environmental release of eluates.

General Comments: Corden BioChem GmbH Corden Biochem International GmbH Industriepark Hchst Brningstrae 50 65929 Frankfurt Germany Select the relevant boxes that cover the content of your comments and provide your non-confidential comments below, (maximum 63 999 characters) Scope or restriction option analysis o Hazard or exposure o Environmental emissions o Baseline o Description of analytical methods Information on alternatives Information on benefits Other socio economic analysis (SEA) issues Transitional period Request for exemption Corden BioChem GmbH and Corden BioChem International GmbH are an industrial production partner for biotechnologically manufactured products in the sector of food, feed additives, enzymes and for technical applications.

Droog opgwerkte AEC-bodemas Omschrijving Algemene monstervoorbehandeling Aantal Metingen Samenstelling Laboratorium Samenstelling Perfluorobutanoate (PFBA) Perfluoropentanoate (PFPeA) Perfluorohexanoate (PFHxA) Perfluoroheptanoate (PFHpA) Perfluorononanoate (PFNA) Perfluorodecanoate (PFDA) Perfluoroundecanoate (PFUnDA) Perfluorododecanoate (PFDoDA) Perfluorotridecanoate (PFTrDA) Perfluorotetradecanoate (PFTeDA) Perfluorohexadecanoate (PFHxDA) Perfluorooctadecanoate (PFOcDA) Perfluorobutane sulfonate (PFBS) Perfluoropentane sulfonate (PFPeS) Perfluorohexane sulfonate (PFHxS) Perfluoroheptane sulfonate (PFHpS) Perfluorodecane sulfonate (PFDS) 4:2 Fluorotelomer alcohol (4:2 FTOH) (H4PFOS) 6:2 Fluorotelomer alcohol (6:2 FTOH) 8:2 Fluorotelomer alcohol (8:2 FTOH) 10:2 Fluorotelomer alcohol (10:2 FTOH) 2,3,4-tetrafluor-2-(heptafluorpropoxypropanoic acid (HPFO-DA) Perfluorooctanesulfonamide (PFOSA) 2-(N-methylperfluorooctanesulfonamido) (N-MeFOSA) 2-(N-methylperfluorooctanesulfonamido) acetic acid (N-MeFOSAA) N-ethylperfluorooctanesulfonamidoacetic acid (N-EtFOSAA) Sodium bis (1H, 1H, 2H, 2H-perfluorodecyl)phosphate (8;2 diPAP) PFOA (linear) Perfluorooctanoate(PFOA) (branched) PFOA (som) Perfluorooctane sulfonate (PFOS) (branched) Perfluorooctane sulfonate (PFOS) (linear) PFOS som PFBA PFPeA PFHxA PFHpA PFNA PFDA PFUnDA PFDoDA PFTrDA PFTeDA PFHxDA PFOcDA PFBS PFPeS PFHxS PFHpS PFDS 4:2 FTOH 6:2 FTOH 8:2 FTOH 10:2 FTOH HPFO-DA (GenX) PFOSA N-MeFOSA N-MeFOSAA g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds N-EtFOSAA 8:2 diPAP PFOA(l) PFOA(b) PFOA(s) PFOS(b) PFOS(l) PFOS(s) g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds g/kg Ds Gemiddelde stdev Min 48 Meeste in duplo Aantal metingen 62 Nu opgenomen grenzen (grond op landbodem, Aantal kleiner dan Max 95Percentiel wonen of industrie) bepalingsgrens 0,56 0,75 0,07 5,40 1,10 0,14 0,13 0,07 0,60 0,40 0,42 0,53 0,07 2,00 1,70 0,14 0,13 0,07 0,60 0,40 0,14 0,26 0,07 2,00 0,35 0,16 0,19 0,07 1,30 0,35 0,10 0,08 0,07 0,35 0,35 0,09 0,06 0,07 0,35 0,22 0,10 0,08 0,07 0,35 0,35 0,10 0,08 0,07 0,35 0,35 0,10 0,08 0,07 0,35 0,35 0,29 0,47 0,07 1,40 1,40 2,27 2,33 0,07 7,50 6,70 0,11 0,09 0,07 0,35 0,35 0,19 0,24 0,07 0,90 0,70 0,10 0,09 0,07 0,35 0,35 0,10 0,08 0,07 0,35 0,35 0,20 0,56 0,07 3,60 0,35 2,04 3,04 0,07 15,00 7,91 0,23 0,32 0,07 2,10 0,50 0,12 0,10 0,07 0,40 0,35 0,34 1,01 0,07 6,60 0,67 0,10 0,08 0,07 0,35 0,35 0,10 0,08 0,07 0,35 0,35 0,12 0,17 0,07 1,30 0,35 0,11 0,09 0,07 0,35 0,35 0,10 0,08 0,07 0,35 0,35 0,37 0,31 0,07 1,32 1,04 0,10 0,07 0,07 0,36 0,31 0,46 0,33 0,00 1,42 1,16 0,52 0,79 0,07 3,07 2,41 0,23 0,29 0,07 1,27 1,03 0,71 1,05 0,00 4,34 3,31 3,00 17 3,00 48 3,00 31 3,00 45 3,00 54 3,00 45 3,00 59 3,00 47 3,00 61 3,00 61 3,00 61 3,00 61 3,00 3 3,00 55 3,00 51 3,00 57 3,00 61 3,00 58 3,00 10 3,00 39 3,00 49 3,00 51 3,00 60 3,00 61 3,00 55 3,00 51 3,00 60 13 50 7,00 27 39 3,00 31/10/22

European rail sector's contribution to the public consultation on the PFAS restriction proposal - September 2023 Application for derogations from PFAS REACH restriction for specific uses in railways Contents 1) Introduction .................................................................................................................................... 4 The European rail sector ..................................................................................................................... 4 Preliminary statement and structure of the document ...................................................................... 7 List of abbreviations and chemicals .................................................................................................... 9 2) Where are PFAS used in railways and why?

RESEARCH DEFLUORINATION Low-temperature mineralization of perfluorocarboxylic acids Brittany Trangl t, Yuli Xiao-Song Xue4, Mohamed Ateial f, K.

Processed product for chemical plant applications Applicationr: Chemical Plant Materials used in the field are PTFE (CAS NO: 9002-84-0), PCTFE (CAS NO: 9002-839), PFA (CAS NO: 26655-00-5), PVDF (CAS NO: 24937-79-9), and ETFE (CAS NO: 94228-79-2).

Finnish Textile & Fashion Association's views on the U-PFAS Restriction Proposal Finnish Textile & Fashion Association supports the goal of the restriction proposal to cease the emissions of PFAS substances to the environment.

Specific Information Requests Question 6: Missing uses - Analysis of alternatives and socio-economic analysis a/b.

Drinking water (Kabor et al., 2018) (Boone et al., 2019) (Domingo, 2012) (Eriksson, Krrman, Rotander, Mikkelsen, & Dam, 2013) (Eschauzier, Beerendonk, Scholte-Veenendaal, & De Voogt, 2012; Eschauzier, Hoppe, Schlummer, & de Voogt, 2013) (Eschauzier, Hoppe, et al., 2013) (Essumang et al., 2017) (Haug et al., 2010) (Kunacheva et al., 2012) (Llorca et al., 2012) (Schwanz, Llorca, Farre, & Barcelo, 2016) (Shiwaku et al., 2016) (Brandsma, Koekkoek, van Velzen, & de Boer, 2019; Thompson, Eaglesham, & Mueller, 2011) (Gebbink, Van Asseldonk, & Van Leeuwen, 2017) (Harrad, Wemken, Drage, Abdallah, & Coggins, 2019) (Heo, Lee, Kim, & Oh, 2014) Groundwater 1.

Table 4.15 Fluororesin characteristics list (representative values) Characteristic Melting point Density Tensile strength Elongation Compressive strength Izod impact strength Rockwell hardness Shore hardness Flexural modulus Tensile modulus Dynamic friction Thermal conductivity Specific heat Coefficient of linear expansion Ball pressure temperature Deflection temperature under load Maximum operating temperature (continuous) Volume resistivity Dielectric strength (short term) Dielectric constant Loss tangent Arc resistance Water absorption rate Flame retardance Limiting Oxygen Index (LOI) Effects of direct sunlight Chemical resistance acid alkali Organic solvent Unit g/cm3 MPa MPa [10Deformation] J/m [R scale] [D scale] GPa GPa [0.69MPa, 3m/min] W/mK 103J/kgK 10-5/ K (-30+30) [1.81MPa] [0.45MPa] JIS K 6935 K 7112 K 7162 K 7181 Test method ISO 12086 1183 527 Same above 604 ASTM D 4591 D 792 D 638 D 695 K 7110 180 D 256 K 7202 2039 D 785 K 7215 868 D 2240 K 7171 K 7161 K 6935 A 1412 K 7123 178 527 8302 D 790 D 638 D 1894 C 177 D 696 Compliance with the Report on Registration System for Thermoplastic Ball Pressure Used in Electrical Appliances K 7191 75 D 648 PTFE 327 2.13-2.20 20-35 200-400 10-15 150-160 R20 D50-55 0.53-0.58 0.40-0.60 0.1 0.23 1.0 10 180 55 120 cm[50%RH,23] MV/m [3.2mm Thickness] [ 60Hz] [103Hz] [106Hz] [ 60Hz] [103Hz] [106Hz] sec [24hr] [3.2 Thickness] K 7226 K 6911 K 6935 K 6935 K 6935 K 7209 K 7140 K 6935 2578 IEC 60093 IEC 60243 IEC 60250 IEC 60250 62 1210 4589 D 257 D 149 D 150 D 150 D 495 D 570 UL-94 D 2863 D 543 260 >1018 19 2.1 2.1 2.1 0.0002 0.0002 0.0002 >300 0.01 V-0 >95 Non S.E S.E S.E PFA 310 2.12-2.17 25-35 300-350 15-20 non breaking R50 D62-66 0.54-0.64 0.31-0.35 0.2 0.19 1.0 12 230 47 74 260 >1018 20 2.1 2.1 2.1 0.0002 0.0002 0.0003 >300 0.01 V-0 >95 Non S.E S.E S.E FEP 260 2.15-2.17 20-30 250-330 14-19 non breaking R50 D60-65 0.55-0.67 0.32-0.36 0.3 0.2 1.2 9 170 50 72 200 >1018 22 2.1 2.1 2.1 0.0002 0.0002 0.0005 >300 0.01 V-0 >95 Non S.E S.E S.E PCTFE 220 2.10-2.20 31-41 80-250 31-51 135-145 R80 D75-80 1.25-1.79 1.03-2.10 0.4 0.22 0.9 6 170 90 126 120 >1018 22 2.6 2.6 2.6 0.0012 0.025 0.020 >300 0.01 V-0 >95 Non E E V.G ETFE 270 1.73-1.74 38-42 300-400 40-50 non breaking R50 D67-78 0.90-1.20 0.70-0.85 0.4 0.24 2.0 6 185 74 104 150 >1017 16 2.6 2.6 2.6 0.0006 0.0008 0.005 75 0.03 V-0 32 Non V.G V.G V.G ECTFE 245 1.68-1.69 41-48 200-300 35-40 non breaking R50 D53-57 0.66-0.69 1.55-1.70 0.4 0.16 2.0 8 180 77 116 150 >1015 20 2.6 2.6 2.6 0.0005 0.0015 0.015 18 0.01 V-0 60 Non E E E PVDF 151-178 1.75-1.78 30-70 20-370 32-74 160-375 R93-116 D64-79 0.60-1.99 0.37-2.58 0.4 0.17 1.2 16 150 100 156 150 >1015 11 8.4 7.7 6.4 0.049 0.018 0.017 60 0.03 V-0 43 Non E V.G G PVF 203 1.38-1.57 (82) 115-250 (1.9) 0.14-0.17 1.0 7.1-7.8 100 >1014 8.2-8.5 6.2-6.7 6.2-7.0 0.3 <0.5 HB 23 Non G V.G G Super Excellent(S.E): Not attacked by most chemicals and solvents even under harsh conditions.

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Socioeconomic effects of Co. 2mag AG products, in 2022 Market segments Research & Development in chemical-labs Research & Development in analytical-labs Pharmaceutical laboratory equipment Process control, quality testing EHSA (Environmental health & safety) Medicine development technology Summary Turnover (mio.

General Comments on the Annex XV Restriction Report for Per- and polyfluoroalkyl substances (PFASs) dated 22.03.2023 PUBLIC VERSION Confidential Business Information is REMOVED. .