AARR2R2R6E-3366338 & Ne.

CASE REPORT p. 1 ~70 9 Acute Pulmonary Toxicity Linked to Use of a Leather Protecto r s From the Centre Anti-Poison du trlaFtu tatie.n:,, MD, FRCP(C) Leather protectors are used extensively for waterproofing leather Quekc' S'"&-Foy, Q"&", Ca"d .

23) OECD 205-OPPTS 850.2200, Acute avian toxicity (Northern Bobwhite), 454-112 T-74 85 : A DIETARY LC50 STUDY WITH THE NORTHERN BOBWHITE SANITIZED WILDLIFE INTERNATIONAL, LTD.

oex pct : ART6-0133 International Research and Development Corporation _r---335 | SPONSOR: cowpounD: SUBJECT: 3M Conpany Fluorad Fluorochemtcal Surfactant FC-95 90-Day Study.

.

Experiment No.: conducted at: Dates Conducted: Conducted By: Acute oral Toxicity Screen with 1-2574c00 in Albino ats RECEIVED OCT - 31379 TOXI3CmOLOGY 0979m80037 SRStia.kfeertPayuLlaE,bvoarlMauitanotnrieiosenost,aLabToncr.astory August 6, 1979 to September 6, 1979 DLDaLbWo.UratvaoMrriyeosTa,ench3k7n.oicgiahn- aDarteg : der mx.21.. cmabseens (2) WE.lo..

\0 AR 26 _ 1009 FLUORO DIVP ISIO ON LYME[fR ifiS PR 1G 798 April 13,2001 DMirr.ecCthoarr,leCsheAmuiecral Control Division U4OSf0Ef1incMveiSortfPoeonelmtle,untStiVao.nl,PPreostteicctiidoensAagnednTcoyxic Substances.

*6pf AR226 _ [0 3 EPA / SPI FMG Meeting January 30,2002 Agenda Introduction = Toxicology/PK Program Studies underway Progress o Time line = Ed 3 Environmental Effects/Fate Testing program * Environmental distribution Summary | PROJECT SUMMARY REF: APFO -2 SPONSOR (AsahiAGPlMasEs,PDTuFPEonCto,mDmyintetoene,MDeamikbienr,sAuasnidmAonPtF,OSoSluvpapyl,ieArtsoFina 3M, Miteni) CHEMICAL sTUDY Ammonium Perfluoro-octanoate (APFO~ FC143) Preliminary 4 week oral toxicity study in Cynomolgus monkeys. 6 month oral toxicity study in Cynomolgus monkeys to include an additional 13 week recovery period PURPOSE To understand the particular, to study toxicity of APFO in the effects on the liver, a on sub-human pancreatic primate. function, In on| homone levels administered dose and and to understand APFO levels in the body relationship between fluids (eg plasma) and tissues.

6lef Hs Ee ARARG - 1247 : 3M February 13, 2003 Document Control Office (DCO) OUfSfiEcneovifroPnomlleunttiaoln PPrroetveecnttiioonnAagnednTcoyxics EPA East, Room 6428 1201 Constitution Avenue, NW Washington, DC 20460 (OPPT) VIA FEDERAI EXPRESS FIT -0203_01378 Attention: Docket No.

ARR EG -- 1828 Final Report on A Pharmacokinetic Study of Potassium Perfluorooctanoate in the Cynomolgus Monkey ~~T-757:!

Telomer Research Program AR226-1432 Report Title: 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoroTerrestrial Plants Toxicity, Seedling Emergence RECEIVED OPPT NCIC 2003 July 18 1:00PM Author(s): Silke Fiebig Contractor: Dr.

{AR 226-0538 MICROTOX TOXICITY TEST TEST SUBSTANCE Identity: Perfluorooctylsulfonate, didecyldimethylammonium salt; may also be referred to as Fluoroalkyl ammonium derivative. [1D1,e1c,a2m,i2n,3i,u3m4,,4N,-5d,e5c,y6l,-6N,,7N,-7d,i8,m8e,t8h-yhle-p,tasadletcawfiltuhoro-1- octanesulfonic acid (1:1), CAS # 251099-16-8] Remarks: The 3M production lot number was Lot 1.

AR 2%6-054% Perfluorooctane Sulfonate: Current Summary of Human Sera, Health and Toxicology Data 3M January 21, 1999 ) 000014 Jaary 21,1999 TABLE OF CONTENTS EXECUTIVE SUMMARY cscs I.

AR226 -0715 ACUTE TOXICITY TO FISH (RAINBOW TROUT) IEST~S ~ UBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR 226 -- 0835 ACUTE TOXICITY TO FISH (FATHEAD MINNOW) IEST~S ~UBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-600. (1-Octanesulfonic acid, 1,1,2,2,3,3.4,4,5,5,6,6,7.7.8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The 3M production lot number was 628.