AR226-0191 OES `Compound-Specific, Quantitative Characterizationof Organic Fluorochemicals in Biological Matrices Kcisen) Hae;LisA.Clemens; Mark .

ems ttn pvr nin 00 FIRA9e 030M Studies and Other Information on Certain Perfluorooctane Sulfonate-Related Compounds [iwoasrosen|eippeorossass somemitostpt ene Acute Toxicity 1) Acute Oral Toxicity Screen with T-3493 in Albino Rats, Safety Evaluation Laboratory, Riker Laboratories, Inc., Project No. 0884AR0010, 3M Reference No.

AR226-0%6 TOXICITY TO AQUATIC PLANTS (e.g., Algae) TEST SUBSTANCE Identity: ammonium salt, CAS # 3625-26-1) Perfluorooctanoic acid, ammonium salt; mayalso be referred to as.

ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE Identity:A mixturecontainingperfluorooctanesulfonatweh,ich may alsobe referredto as PFOS, FC-95, oras a component of FX-3106. (1Octanesulfoniaccid)(CAS # 2795-39-3).

| IdnotternaHlTC se <nc2ea-3 ARNVE-0278 EW..GC..

MICROBICS MICROTOX TOXICITY TEST TEST SUBSTANCE Identity: tPoerafsluPoFrDodSe,caFnCe-s1u2l1f-oXn,atoer,3aMmmSoanmipulem Esa2lt1;1m2aayndalEs2o56b6e-1r.efe(r1r-ed D1e,c12a,n2e.s3u.l3f,o4n.i4c.5a.c5i6d,.6,7,7,8,89.9.10,10,10-heneicosafluoro-, ammonium salt, CAS # 67906-42-7) pRreompaarnkosl,: 1T-e(s1t.1s-daimmpeltheylisetahomxiyx)t.ureThoifsthmeixtteusrtescuobnsttaainncseaipnprwoaxtiemraatenldy22-2- p2e6r%fltueosrtonsounbasnteasnuclef,on3a3t-e3,7a%mpmroonpainuoml, s1al-t(1a,n1d-d3im8e-t4h2yl%etwhatoexry))., 0.5-1.5% All values trheepoarctteudalrecloantceetnotrthaitsiomnixtoufrteh.e tNesotcsaulbcsultaatnicoensinwetrheetmesatdseamtpolaed.jusTtesftor material was from 3M production lot 1 Note: Only the summary page was available for this study METHOO Method: Microbics Microtox Procedure Test type: Static acute GLP: Year CNomopleted: 1987 ASnpaelcyiteisc:alPhmootnoibtaocrtienrgi:uNmopnheosphoreum TSteasttisotircgaalnmiestmhsoodusr:ceM:icMriocbriocbsiccsomMpiuctreortosxoftRweaargeepnatckage RTeepslticcoantdeist:ioTnws:o Per Microbics method RESULTS TNeosmtinSaalmpcloneceEnltermaetnitonvsa:lu1e2s5:, 2550-,mi50n0u,te1E0C0s0)m=g6/4L0 (605-670) mg/L 15-minute ECso =290 (260-310) mg/L All element values based on nominal concentrations.

J.

PER6SCOONFINDEANTILAL

AR226-2940 FOR DU PONT USE ONLY Du Pont HLR 391-89 Study Title Approximate Lethal Dose (ALD) of ^n Rats Author John M.

TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE Identity: NN--eEtthyFlOpSeErfAllucoorhooocltoarneFMs-u3l4f2o2n.ami(d1oe-tOhcatnaonle;sumlafoynaamlsiodeb,eNr-eeftehryrle-d to as 1.12.2.3,3,4,4,5,5,6.6,1.7,8,8,8-heptadecafluoro-N-(2-hydroxyethyl)-, CAS # 1691-99-2) Remarks: Mjaimtietreidalwaitsearnsooflfu-bwilhiittyeo,fwtahixsymsaotleidrioaflupnrcohhairbiatcetderaizdeefdinpiutriivtey.

AR 226 -- 0 80/ BIODEGRADATION (BOD/COD) TEST SUBSTANCE Identity: AbemriexfteurrreedcotnotaaisnPinFgOSpe,rfFlCu-o9r5o,ocotranaessuaifcoonmapteo,newnhitcohfmFaCy-2a0l6soC and L-5439. (1-Octanesulfonic acid, s1a1l,t,22C,A33S,4#,42,759,55-63,96-,37),7,8,8,8-heptadecafiuoro-, potassium Rreefmearrrekdst:o asTLh-e5433M9 apnrodduFcCt-i2o0n6lCo.t nCuumrbreerntwiansfo5r0m1a.tiTohneitnedsitcastaemspilties ias mixtureof 0.73% PFOS, 76.09% water, 15% diethylene glycol butyl ether, 4po%lyuorxeyae,th1y.l5e5n%e smoondoioucmtoycltpyhlesnuyllfaette,he1r,.407.%06h%ydsroodxiyufmoalmauerry,l 1su.l0fa5t%e, and 0.05% benzotriazole. sTthuedifeoslloonwiFnCg-i2s0a6nC.abbTrheevsieatsetdudsiuemsmaaprplyyotfomutlhtetieplsetsbiaomdepgrlaaesdataion `Dmaitxatudroeewsitnhotinaccocmuprlaetteellyyrcefhlaercatcttheeribzieoddecgornacdeanttiroatnipoonteonftiimapluorfittihees. fluorochemical component of thetest sample.

: HASKEALLNDLAIBNODRUASTTORRIYALFOMREDITCOIXNIECOLOGY Trecho Lo apis cc: G.

AR226-2797 Du Font HLR 150-88 POP DO FONT OSB ONLY Study Title IN VmO^IOCOMPATAHLITY-EVALUAKOy____________________ WITH IMR-90 HUMAN DIPLOID FIBROBLASTS IN THE OTT COLORIMETRIC ASSAY" Author Ralph G.

FOR DU POST USE ONLY AR226-2928 Approximate Lethal Concentration by Inhalation (ALC) of Haskell Laboratory Report No. 279-85 Haskell E.

Noma met 16 1.