The term "Dioxin" has recently become a household word, as had asbestos, PCB's and DDT during the last decade.

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C :\PROJECTS\MONTAGUE\SUSKIND ADDENDUM TO PAT'S REPORT (Unless otherwise noted, all references are to page and exhibit numbers in Pat's report.) / CHANGE IN STUDY DESIGN: THE MISSING COHORT The Zack/Suskind mortality study of 1949 explosion workers with chloracne states (p. 11): "The results of this study will be incorporated with those of a larger study which will include plant workers exposed in the course of 2,4,5trichlorophenoxyacetic acid production during the period 19481969," and (p. 12) "An analysis of the chloracne cases and ex posures not associated with this accident but rather with the normal TCP/2,4,5-T production processes will be the subject of a future paper." (2,4,5-T was produced at Nitro from 1948 through 1969.)

'll 'AL MEDICINE 4.

c . c* T i. < t o : Plant File .

** GROUP I -- 114 employees exposed to dioxin in a 1949 TCP accident and developed chloracne have been identified for study.

GROUP I - 1 1 4 employees exposed to dioxin in a 1949 TCP accident and developed chloracne have been identified for study.

1947 N ational E lectrical C ode STANDARD OF TH6 National Board of Fire Underwriters FOR ELECTRIC W IR IN G AND APPARATUS AS DECOMMENOED O* THE NATIONAL FIRE PROTECTION ASSOCIATION AMERICAN STANDARD Approved October 4, 1946 ' by AMERICAN STANDARDS ASSOCIATION JANUARY, 1947 CHAPTER 1.

M onsanto Chemic. ai Nitro, V.

VK^o^a Monsanto fr* ** too n *.*# it i**.uii*" iw* D U tM -tO O O August. 39, 19Bt Dr.

i)0 5 2 l) ATTACHMENT G Suskind T a lk s A b o u t M o n s c n to S tudy 2C ( i t toe's Hate: H e hatheida w M r uteri h r JO ;* * n f* fNtfW f f f t M i farmi and- forest lends. ft k i II i| n Olllfl, w*cfc III Aeviif tgrarai m Y*etamm Im iaprxaa Caatmaatit m i l l at corar.

Ky Pates - Woninto Manufacture of 2,4,5-TlcMorophepol 19491953 19491969 12/78 Manufacture litro initiated.

f 't VOL 3- > 'o . 5 'i; J A --* > 's*&&*'.

f Zack/Suskind Study "The Mortality Experience of Workers Exposed to Tetrachlorodibenzodioxin in a Trichlorophenol Process Accident" Study Criteria Population: Start Date: End Date: Exclusions : Vital Status: All persons with chloracne which could be attributed to the 1949 TCP process accident.

^ IVtiM o n sa n to C h e m ic ai Nitro, W.