Z 47 REV. 1-80 <m m W uinw^ ESTABLISHED 0 2 > E .

6 0 P- 31 October 2003 AR226-1642 To: Mary F.

BACK TO MAIN 3M FLUOROCHEMICAL SUBMISSION TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE July 2004 Click on Study Title to View Report July 16, 2004 Molecular Biology Study: Amendment to Final Report, "Comparative Molecular Biology of Perfluorooctane sulfonate(PFOS, T-6295), N-Ethyl perfluorooctanesulfonamido ethanol (N-EtFOSE, T-6316),N-Ethyl perfluorooctanesulfonamide (N-EtFOSA, T-6868), Perfluorooc tanesulfonamidoacetate (FOSAA, T-7071), and/or Perfluorooctanesulfonamide (FOSA, T-7132) of in[sic] Rats and Guinea Pigs following Oral dosing," 3M Medi cal Department CorporateToxicology, DT-15-B, July 16, 2004 (revising page 59).

BACK TO MAIN 3M FLUOROCHEMICAL SUBMISSION TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE May 2000 Click on Study Title to View Report May 2, 2000 Cell Proliferation Study: In-Life Appendix, "Cell Proliferation Study with N-Ethyl Perfluorooctanesulfona mido Ethanol (N-EtFOSE; 3M T-6316.11), Perfluorooctane Sulfonic Acid Potassium Salt (PFOS; 3M T-6295.16), and N-Ethyl Perfluorooctansulfonamide (PFOSA; 3M T-7091.1) in Rats," TherImmune Research Corporation, TRC 1132-100, May 2, 000 (Appendix 1 to full report).

SRPT T-6295.8, T-6316.4, T-6868.2, T-7071.1, T-7132.1 DT15-B 3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY Title: Comparative Molecular Biology of Perfluorooctanesulfonate (PFOS, T-6295), N-ethyl perfluorooctanesulfonamido ethanol (N-EtFOSE, T-6316), N-Ethyl perfluorooctanesulfonamide (N-EtFOSA, T-6868), Perfluorooctanesulfonamido acetate (FOSAA, T-7071), and/or Perfluorooctanesulfonamide (FOSA, T-7132) of in Rats and Guinea Pigs following Oral dosing.

AfUL26 - 06?

M &SL& - 0 7 lf-lh TO XIC ITY TO AQUATIC PLANTS TEST SUBSTANCE_______________________________________________ Identity: A mixture containing perfluorooctanesulfonate; may also be referred to as PFOS, FC-95, or as a component of FC-203C and L-5440. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-, potassium salt, CAS # 2795-39-3) Rem arks: The 3M production lot number was not noted.

ftR A & 6 - 0 7 4 8 READY BIODEGRADATION (OECD 301E) TEST SUBSTANCE________________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203CE. (1Octanesulfonic acid) (CAS # 2795-39-3).

M 2.2.6 _ 0 7*75" ACUTE TO XICITY TO FISH TEST SUBSTANCE Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-203S. (1Octanesulfonic acid) (CAS # 2795-39-3).

A ft 9l8l6 - 077g BIODEGRADATION (301E) TEST SUBSTANCE____________________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-206. (1Octanesulfonic acid) (CAS # 2795-39-3).

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Katherine E.

2K2N0V 11 AH 11=56 lOT ff REVISED DRAFT HAZARD ASSESSMENT OF PERFLUOROOCTANOIC ACID AND ITS SALTS U.S.