BACK TO MAIN 3M FLUOROCHEMICAL SUBMISSION TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE October 2005 Click on Study Title to View Report October 7, 2005 POSF 5-day Inhalation Toxicity Study: Final Report, "Perfluorooctanesulfonyl Fluoride (POSF; T-7661.1) Preliminary Tox icity Study by Inhalation Administration to CD Rats for 1 Week," Huntingdon Life Sciences Ltd., Study No.

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Corporate Occupational Medicine 3M Center, Building 220-3W-05 St.

AfOT'050$ CHRONIC TOXICITY TO FRESHWATER INVERTABRATES (Daphnia magna) TEST SUBSTANCE Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA ammonium salt, Ammonium perfluorooctanoate, FC116, FC-126, FC-169, orFC-143.

Report EO1-1245 PFOS: A Reproduction Study with the Nothem Bobwhite Study Title Analytical Phase R e po r t for PFO S : A R e pr o d u c tio n Stu d y w ith T he No r th e r n Bo b w h ite Data Requirement F IF R A Subdivision E, Section 7 1-4 O E C D Guideline 206 Author Lisa A.

AR226-1942 31 March 2005 " To: Mary F.

Telomer Research Program AR226-1943 RAelcpoohrotlsTitle: Extended Laboratory Study of the Atmospheric Degradation of Fluorinated Author(s): Professor Georges Le Bras, Geraldine Solignac and Dr.

Atlanta Denver tos Angeles Philadelphia T homas B.

AR226-2009 AGENDA C-ft REVIEW - APRIL 26, I.

AR226-2041 To: Partick J Cavanagh/Cl/DuPont@ DuPont cc: Roger J Zipfel/AE/DuPont@ DuPont S u b ject 6/9/99 C -8 Sam pling Pat, Samples were taken today from 1:30 PM to 6:00 PM in the following locations: inside the C-8 recovery building inside the C-8 recovery building control room recovery building roof smoking area roof area outside lunchroom The wind conditions were 3-5 mph out of the north at the start of sampling and out of the south/east at the end of sampling.

MScoodpeeliannad Cost of Air Dispersion Cathie Barton DuPont 03/10/03 AR226- Overview of the Scope Can hire contractor or use inhouse modeling resources GaDthaetraing Modeling InotefrRpreestualttison Ycoriutircianlphuetreis 03/10/03 Data Gathering Meteorological Data * Terrain elevation maps Stack Parameters - Location (coordinates) Minofdoegrlemeytrsaotttuyihopinsicfaolrly - Height - Temperature - Stack gas vertical velocity - Diameter - Emission rates for each compound Plot Plan - Exact locations of all sources - Property line - Building locations and heights EID 719401 03/10/03 Standard Model and Methodology EPA's preferred model: Industrial Source Complex Short Term 3 (ISCST3) Model Procedures detailed in EPA's Guideline on Air Quality Models (40 CFR 51 Appendix W) http://www.epa.gov/scram001/guidance/gui de/appw_01.pdf M H 03/ 10/03 Modeling Output Model will calculate hourly concentrations in ug/m3 across a study area (5 km x 5 km for example) Model will average those concentrations over a designated time period (24 hour, monthly, yearly) Concentration contours showed extent of different ug/m3 Also shows numerical values (top 10 in the study area and locations) 03/ 10/03 Technicolor Example of Output WcGnO EID 719404 r_ Interpretation of Results Compare maximum averaged concentration to appropriate "threshold" value - Maximum annual average would be compared to a chronic toxicity value - Maximum hourly average would be compared to an acute toxicity value P O Oo wcn 03/10/03 to EX D 719405 Cost and Timing Expect about 50 man-hours (_10 hours) Costs - Outside modeler charges approximately $150/hr - Meteorological data could be up to $1,000' - Estimate around $8,500 for an average job. o o owcn 03/10/03 o EID 719406

AR226-2439 INTEROFFICE MEMORANDUM Date: From: Dept: Tel No: 04-Feb-1997 05:45pm DAVID S.

AR226-2495 h m 123 08/31/01 1 1 :0 1 5 :0 4 /13 N0:150 Meorr jufc.l -vwst July 18,2001 iSSSl||C0RT REQUESTED ?

B R -ih June 6, 1997 CluPsnt WashingTM Worts P. 0.

AR226-2588 "Andrew > Martien l0//1B/UU2 4:1 HW To: stvs.williams@epa.etata,oh.us cc: Bernard J Reilly/AE/DuPont@DuPoM, Laura R Walter/AE/DuPont@DuPont, M.