Document 37yKO1gZq004Mp6moQ1JxZwR0

AR226-2010 C-8 BLOOD DATA (WASHINGTON WORKS) STATUS OF EMPLOYEES AS OF: 0.5 p p m 5 1,0 p p m 5.0 p p m 10 ppm >10 p p m BASE DATA 1984-1985 (108 PEOPLE) 22% (24) 67% 92% 97% (73) (100) (105) 3%` (3) 1987 (31 p e o p l e ) 1988 (28 PEOPLE) 1987-1988 Co m b i n e d (58 p e o p l e ) 1989 (41 p e o p l e ) 26% (8)' 43 (12) 34% (20) 34% (14) 39% (12) 61% (17) 50% (29) 59% (23) 87% 97% 3% (27) (30) (1) 93% 100% (26) (28) 0% 90% 100% (52) (58) 0% 83% 98% 2% (34) (40) (1) o Th i s d a t a is ONLY USEFUL TO p r o v i d e A GENERAL OVERVIEW (a s n a p s h o t IN TIME). o No t u s e f u l f o r t r e n d s b e c a u s e o f p e o p l e m o v e m e n t , a n d t h e COMPOSITION OF PEOPLE TESTED CHANGES EACH YEAR. H. A. Smith March '90 B:44 #4 AJP01664 EID080174 DREfVpIcEOWNNOEFLWaAiSrHImNoGnTiOtNorWiOnRgKSANCB-_8BLSDfAlBT_A. Th e r e v i e w o f b l o o d d a t a v s . c u r r e n t p e r s o n n e l monitoring n.T . MII<:T d b VIEWED AS A TECHNICAL STUDY WHICH DEMONSTRATES THE " s C-8c o r r e l a t i o h ^b e t w e e h iu air, s k i h e x p o s u r e , a d b l o o d l e v e l s . tSe a b s ^ S t e lev e l s a r e d i f f i c u l t to i n t e r p r e t b e c a u s e t h e b l o o d IPVPLS ARE INFLUENCED BY PEOPLE S EXPOSURE GOING BACK 10 YEARS (C 8 S p ! i F F ^ i r i u . THi RLOOD is VERY, VERY SLOW), AND THE PERSONNEL AIR MONITORING RESULTS ARE CURRENT DATA. C-8 PERSONNEL AIR MONITORING DATA TAKEN OVER * 1 q r r t m b o u c h Se p t e m b e r 1989 (220+ s a m p l e s c o v e r i n g 22 j o b s ) a n d a l l PERSONNEL^C-8 IN^BLOOD DATA GOING BACK TO 1979-80, WERE SUMMARIZED AND REVIEWED. WHEN CORRELATING BLOOD DATA WITH AIR MONiTORING DATA nY pcDC j o b s THE ONLY PEOPLE INCLUDED IN THE BLOOD DATA BASE WERE S o E ? W H O "K d BEEN IN THE INDICATED JOB FOR YEARS; AD NOT MOVED ALL TM R THE Flo OROPOLVHERS AREA! AND ARE STILL TH THE JOBS. Th e TASK OF TMTPRPRETING THE DATA IS COMPLICATED BY THE FACT THAT THE AIR MONITORING DATA IS RECENT, WHEREAS THE BLOOD Jfpi"! VERY SLOW DROP-OFF RATE OF C-8 IN THE BLOOD) ESSENTIALLY REFLECTS EXPOSURE DATING BACK TO THE "EARLY DAYS". CONCLUSIONS 1) C-8Ther e i s a c o r r e l a t i o n b e t w e e n personnel air levels AND C-8 IN BLOOD LEVELS, AND BETWEEN SKIN CONTACT AND C-8 IN BLOOD LEVELS. ' Ta b l e 1 s u m m a r i z e s t h e b l o o d d a t a /a i r d a t a /s k i n CONTACT POTENTIAL BY PERS JOBS. THOSE JOBS SHOWING WIDELY DIVERGENT BLOOD LEVEL POPULATIONS ARE THE JOBS THAT HAVE POTENTIAL FOR SKIN EXPOSURE. 2) The EFFECT OF SKIN CONTACT IS STRONG AND APPARENT AS DEMONSTRATED IN TABLE 1 AND FIGURE 1, ESPECIALLY DOCUMENTED by jobs 08PE, 08PH, and 08PF. 3) 7-8 TM!^!;Skin c o n t a c t r e s u l t s in b l o o d l e v e l s in t h e p OR WAY HIGHER. THIS POSITION IS ALSO SUPPORTED BY 3M AND BY REVIEW OF ALL OTHER BLOOD PLOTS WE HAVE; WHERE SOME PEOPLE STAND OUT WITH VERY HIGH BLOOD LEVELS. aFi g u r e 1 i s a p l o t o f p e r s o n n e l a i r l e v e l s f o r PERS JOB c o d e v s . b l o o d l e v e l s f o r t h e s a m e j o b ' c o d e . Fi g u r e 1 a l s o s h o w s t h e h i g h b l o o d l e v e l s THAT DO NOT FIT THE CURVE WHICH ARE ATTRIBUTED TO SKIN CONTACT ON THE PART OF THE SPECIFIC INDIVIDUALS* HAS/lS 4/90 AJP001665 EID080175 z- - 4) 1 AELFi g u r e w o u l d i n d i c a t e t h a t e x p o s u r e a t t h e of 0.56 p p b w o u l d e q u a t e t o a b l o o d l e v e l o f 3 p p m . 5) Ba c k g r o u n d b l o o d l e v e l s , f o r p e o p l e i n TH1S AREA OF THE PLANT, ARE IN THE 0.1-0.5 PPM RANGE. 6) A SIDE OBSERVATION - PEOPLE WORKING IN A JOB SEEM TO _ ACHIEVE THE BLOOD LEVEL FOR THE JOB AND STAY THERE UNLESS THERE IS AN INCIDENT (SKIN CONTACT) OR, IN ONE INSTANCE, A PROCESS CHANGE. 7) Dr o p -o f f r a t e f o r C-8 in t h e b l o o d i s a h a l f l i f e o f 4-5 YEARS OR MORE. THIS IS BASED ON A VERY SMALL AMOUNT OF DATA ON PENSIONERS AND ON THE OBSERVATION THAT THERE IS A SLIGHT PERCEIVED DECLINE IN WORKERS IN THE VARIOUS JOBS, 8) Be c a u s e o f t h e s l o w d r o p -o f f r a t e , a n n u a l b l o o d t e s t i n g is TELLING US NOTHING. WE ARE DISCONTINUING BLOOD TESTING (UNLESS AN EMPLOYEE REQUESTS IT) FOR NOW, AND WILL RECONSIDER TAKING ANOTHER "SNAPSHOT IN A FEW YEARS AFTER WE HAVE COMPLETED OUR PROCESS IMPROVEMENTS (E.6., USE OF C-8 IN SOLUTION). When w e elect to do mor e blood m o n i t o r i n g , we should SAMPLE AS' MANY WORKERS AS POSSIBLE. WE WOULD NEED THE PEOPLE NEW TO THE AREA AS WELL AS THE OLDER WORKERS BECAUSE THE OLDER WORKERS WOULD STILL BE ON THE SLOW DECAY C-8 IN BLOOD CURVE. EVEN AT BEST, THE DATA WILL AGAIN BE DIFFICULT TO INTERPRET BECAUSE OF THE FREQUENT JOB-TO-JOB MOVEMENT OF PEOPLE WITHIN THE FLOUORPOLYMERS AREA, AND FROM AREA-TO-AREA ON THE Wa s h i n g t o n Wo r k s s i t e . Ot h e r c o n f o u n d i n g f a c t o r s THAT WILL CONTINUE TO ADD TO VARIABILITY ARE INDIVIDUAL WORK HABITS AND INDIVIDUAL BIOLOGICAL RESPONSES SUCH AS EXCRETION RATE AND RETENTION IN BODY OTHER THAN IN BLOOD (E.G., FAT). _ 22 PERS9) Ei g h t e e n o f t h e jobs were in compliance with the AEL C-8.f o r Fo u r j o b s w e r e o u t o f c o m p l i a n c e o r m a r g i n a l ; ALL FOUR JOBS INVOLVED POTENTIAL FOR SKIN EXPOSURE. USE OF C-8 IN SOLUTION SHOULD ELIMINATE THE PROBLEM FOR THREE OF THE FOUR JOBS. HAS/lS 4/90 AJP001666 EID080176 EID080177 99lOO<lfV ASSESSMENT OF BLOOD VS. AIR M1 SS 08PE Poly Autoclave Operator 08PX Poly Dryer/Envirohmental Control Operator 18PB FEP Extrusion/Oven Operator 08PH Poly Dispersion Operator 08PF Poly Polykettll Operator 08PG Granular TA Zone 6 Operator 08PK Granular TA 3rd Floor Operator 18PA ,, FEP Polykettle Operator 6SHE FEP General Day Mechanic .Rrnon (ppm) 3 7 (Data showed two populations) 2 QS S'tL 1R (PPB> 0.66 0.25 8*5 <0.03 (NO) 0.08 7,5 (ONE person) (Data showed two populations) 25 sis (ONE PERSON) (Data showed two populations) 0.27 0.4 <0.0*3 (NO) 0.1 . .05 NO DATA No DATA 5.97 0.58 Handles C-8 Potential for Skin Exposure Yes* AEL r.dMPLIANCE No No No Yes* Yes* Yes Yes Yes Marginal No No Yes* Yes Yes Yes No Marginal * C-8 IN SOLUTION use should eliminate this problem Crawley/Lanyon/Loschiavo/Smith - 11/89 S tjt i cor- m <m r~ o o o r i WASHINGTON W ORKS DATA blood levels VS. air exposure levels (BY JOB) fHid uo 0o3 H <1 03 899TOO<IfV