6 _ II^B FINAL REPORT IN VIVO RAT MICRONUCLEUS ASSAY COVANCE STUDY: 22900-0-4540ECD STUDY SCHEDULE: Study Initiation Date: 18-Oct-2001 Initial Dose Date: Study Termination Date: Final Report Date: 23-Oct-2001 19-Nov-2001 25-Jan-2002 rc<Us3s2sy3 G>?

Northwest Bioanalytical A H & 8 l6 - >A I J L Study No.

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| Andrew S Hartten 11 /0r2002 08:55 AM f To: Vic E KleInfelter/AE/DuPont@DuPont cc: Seiichi Tanaka/PO/DuPont@DuPont.

FOSA 3M FLUOROCHEMICAL SUBMISSIONS February, 2002 - May 11, 2004 TOXICOLOGY, EPIDEMIOLOGY AND MEDICAL SURVEILLANCE Click on Study Title to View Report Perfluorooctanesulfonamide Toxicokinetic Study 1.

3M Strategie Toxicology Laboratory Study Title: Acute Inhalation Limit Toxicity Study of Perfluoroctanesulfonyl Fluoride (POSF) T-7098.3 Test Number (sample): T-7098.3 (Perfluoroctanesulfonyl Laboratory Project Identification: ST64 In-Life Initiation Date: 5/1/2001 In-Life Completion Date: 5/14/2001 Fluoride(POSF) Research Client: 3M Specialty Materials Division 3M Center Building 236 Saint Paul, MN 55133-3220 Testing Laboratory: 3M Strategic Toxicology Laboratory 3M Center Building 270-SB-181 1 Saint Paul, MN 55133-3220 Study Director: Andrew M.

.Wildlife International Ltd. -1 - Project Number 454A-1Q2 PFOS: A 96-HOUR STATIC ACUTE TOXICITY TEST WITH THE FATHEAD MINNOW (Pimephales promelas) ADDENDUM WILDLIFE INTERNATIONAL, LTD.

ARX&0357 CHRONIC TOXICITY TO FISH TEST SUBSTANCE Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N-EtFOSE Alcohol or FM-3422. (1-Octanesulfonamide, N-ethyl1 I 1I2 , 2 I3 ,3 )4 ,4 ,5 ,5 ,6 I6,7,7,8>8I8-heptadecafluoro-N-(2-hydroxyethyl)-, C A S# 1691-99-2) Remarks: Material is an off-white, waxy solid of uncharacterized purity.

A r n 6 -o w BIODEGRADATION (ABS/LAS Shake Culture Test) TEST SUBSTANCE Identity: Perfluorooctanoic acid, ammonium salt; may also be referred to as PFOA ammonium salt, Ammonium perfluorooctanoate, PFO, FC-116, FC-126, FC-169, or FC-143.

flRr& 'O 5G\ Summary PFOS Rat Two-Generation Reproduction Study Study Numbers: 3M T-6295.9, Argus 418-008 (in-life), FACT-TOX-012 (analytical).

AR226-2083 C-8 SAHPLIH6 PROJECT PA6E 1 OF 41 SUHHARY OF SPECIAL C-8 SAMPUN6 PROJECT Jennifer Nichols Environmental Lab LSE 9-16-97 EID093252 KID137016 RJZ021182 '.I C-8 SAMPLING PROJECT PAGE I OF 41 TABLE OF CONTENTS - PASE TITLE PAGE........... .................... ......... 1 TABLE OF CONTENTS.................................. 2 INTRODUCTION ....................................... 3 SUMMARY OF AIR MONITORING........................... 4 SUMMARY OF WIPE SAMPLING............................ 5 ATTACHMENT 1: AIR SAMPLING RESULTS ............ ..... . 6 SUMMARY OF AIR SAMPLING PATHSFORWARD.................. 24 ATTACHMENT 2: INVESTIGATION OF HVAC UNITS............. 26 ATTACHMENT 3: SURFACE WIPE SAMPLING RESULTS ........... 30 WIPE SAMPLING CONCLUSIONS/PATHSFORWARD............... 36 FIGURE 1: ROOF HVAC SAMPLING LOCATIONS (AIR) ........... 37 FIGURE 2: ROOF SAMPLING LOCATIONS (WIPE) ........... 38 FIGURE 3: PERCENT RECOVERY OF WIPE SAMPLES........... 39 FIGURE 4: AVERAGE VALUES AT ROOF LOCATIONS........... 40 REFERENCES ......................................... 41 RJ202J183 EID093253 EID137017 C-8 SAMPLING PROJECT PAGE 3 OP 41 In response to the Summary of 1995 C-8 Blood Testing (Playtls, 1995) results, and subsequent 1996 Industrial Hygiene Follow-up Report (Playtls, 1996), an extensive sampling campaign for C-8 in air and on surfaces (wipe testing) was conducted in Teflon* areas.

AR226-2576 GIST Telephone Conference Minutes January 30,2002 Participants Dave Watkins-WVDEP George Dasher - WVDEP Don Criss - WVDEP Dr.

AR226-2598 REVISED GROUNDWATER FLOW MODEL DUPONT WASHINGTON WORKS WASHINGTON, WV Date: January 2003 Project No.: 18983635 7423 CORPO RATE REM EDIATION G R O U P An Alliance between DuPont and UPS Diamond Barley Mill Plaza, Building 27 Wilmington, Delaware 19805 A SH 020280 E D 630708 Revised Groundwater Flow Modal Introduction TABLE OF CONTENTS 1.0 Introduction,-,*.... ........................*****................................ ................................... j 2.0 Site Setting, Geology, and Hydrogeology...................................................................4 2.1 Site Setting.................................................... ......................................... ...........* 2.3 Hydrogeology......................................................................................... 3.0 Primary Data Sources............ ....................................................................................2 5 4.1 ModelDomain and Discretization................................. 9 4.2 Boundary Conditions.... ................................................ ................................. 4.2.1 No Flow Boundaries 4.2.2 Ohio R iver....................... 1 4.2.3 Minor Surface Water Features............................................................ 12 4.2.4 Pumping Wells........ ............................................. 13 4.3 Main Input Values....,...... ............................... ...............*.............................^ 4.3.1 Hydraulic Conductivity......................................................................16 4.3.2 Recharge........ ........................ 1 5.0 Groundwater Model Calibration............ ......................... . - ...................... --......

AR226-2706 28 AR226-2706 Society of Environmental Toxicology & Chemistry Summary of DuPont Presentations North American World Congress November 13-18, 2004 Portland, OR Biotransformation of ,4C-labeled Fluorotelomer substances by microorganisms from activated sludge or soil.