< BIO CO NCENTRATIO N - R EVISED AR2.3.G- IIO S TEST SUBSTANCE ____________________________________________ Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: Sample from 3M production lot number 217.

^ R5 G_ M-I Telomer Research Program (TRP) Update Presented to U.S.

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AR226-1387 M 9 A 6 - IS 7 W ilm in g to n , Dela w a re 19898 POUYM ER W O O U C T S DEPARTM ENT Cx P RiMENTAU station PERSONAL AND CONFIDENTIAL May 19, 1981 TO: DR.

0m DuPont Engineering I February 5, 2003 AR226-1415 DuPont Engineering Barley Mill Plaza - Bldg. 27 Lancaster Pike & Rte. 141 Wilmington, DE 19805 David P.

; 9 pp 3M 3M General Offices Lm K n 55144-ioco 612 733 1110 AR226-1541 - 1003 - l RECEIVER oppt cm : 2003 OCT 2 9 A H i h 01 Bv Courier October 28, 2003 Document Processing Center - CBIC (7407M) 'hh Room 6428 East / Phone 202-564-8940 Attn: TSCA Section 8(e) Coordinator Office o f Pollution Prevention and Toxics US Environmental Protection Agency 1201 Constitution Avenue NW Washington DC 20460-0001 8 EHQ 0 y RE: TSCA 8(E) SUBSTANTIAL RISK NOTICE ON: 1-Butanesulfonamide, 1,1,2,2,3,3,4,4,4-nonafluoro-n-methyl ('N-MePFBA') [CAS 68298-12-4] 63 Dear Sir/Madam: 3M has received preliminary data for a combined repeated dose toxicity study with a reproduction/developmental toxicity screening test in rats conducted with a chemical intermediate, 1-Butanesulfonamide, 1,1,2,2,3,3,4,4,4-nonafluoro-n-methyl [CAS 68298-12-4] (N-MePFBA) indicating reproductive and possible neurotoxic effects.

Enclosure 2 raceAnalyFiteilcdaSelrvices Divisum Pace Analytical Services, Inc. 1700 Elm Street, Suite 200 Minneapolis, MN 55414 Phone: 612.607.1700 Fax: 612.607.6444 3M 3M Multi-city Food Study DecePmrobjeecr t4D-8at,e:2000 Prepared by: Pace Analytical Services, Inc.

Wildlife International.

STUDY TITLE Extraction of Potassium Perfluorooctanesulfonate from Egg Membrane, Albumen, and Yolk for Analysis Using HPLC-Electrospray/Mass Spectrometry DATA REQUIREMENTS Analytical Method Requirements STUDY DIRECTOR Sean Gallagher STUDY COMPLETED ON September 06,2001 PERFORMING LABORATORY / TESTING FACILITY Centre Analytical Laboratories, Inc.

A ftu 6 -c > 3 7 3 ACUTE TOXICITY TO AQUATIC INVERTEBRATES (E.G.

/IfttiG -cm R OCTANOUW ATER PARTITION COEFFICIENT TEST SUBSTANCE_____________________________________________________ Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N-EtFOSE Alcohol or FM-3422. (1-Octanesulfonamide, N-ethyl1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 ,8 ,8 ,8 -h e p ta d e c a flu o ro -N -(2 -h y d ro x y e th y l)-, CAS # 1691-99-2) Rem arks: Material is an off-white, waxy solid.

T-7211.1 FR ST-37 Title Adipate (T-7211) Metabolite Identification in Rats Final Report Date: 2-24-04 3M Medical Department Study Number: T-7211.1 3M Strategic Toxicology Laboratory Protocol Study No.

s r l in y T i n .F.

Toxicological Summary PFOS Dietary Chronic Definitive Reproductive Study: Mallard Test Substance: Perfluorooctanesulfonate (PFOS) Structure: 1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro, potassium salt.

P roven Results.