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A f . 2 . i > 6 f c/ exhibit a P-2 Weekly Morbidity and Mortality Weekly Report ___________May 5, 2006 /Vol. 55 / No. 17 State Prevalence of Self-Reported Doctor-Diagnosed Arthritis and Arthritis-Attributable Activity Limitation -- United States, 2003 Arthritis is costly ($86 billion annually), highly prevalent (affecting 43 million U.S. adults), the leading cause of dis ability, and associated with substantial disparities in pain, activity limitations, and compromised quality of life (1- 3).

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3M Environmental Laboratory AR116- ooz^ k) M ethod Analysis of Potassium Perfluorooctanesulfonate or O ther Fluorochemical Compounds in Urine E xtracts U sing H PL C -E lectrospray/M ass Spectrometry/M ass Spectrom etry Method Number: ETS-8-97.0 Adoption Date: Author: Lisa Clemen, Robert Wynne, Glenn Langenburg Revision Date: Approved By: Laboratory Manager Group Leader ------ _ 7 / u /y 5 Date f/Z-37# Date - A C iu m -____________________ ______________________ Technical Reviewer Date 1.0 Scope and Application_________________________________________________ 1.1 Scope: This method describes the analysis of urine extracts for fluorochemicals using HPLC-electrospray/mass spectrometry. 1.2 Applicable Compounds: Fluorochemicals or other ionizable compounds. 1.3 Matrices: Human, rat, and monkey urine, or other fluids as designated in the validation report.

BACK TO MAIN Centre Analytical Laboratories, Inc. 3048 Research Drive State College, PA 16801 www.centrelab.com ^P hone: (814) 231 -8032 Fax: (814) 231 -1253 or (814) 231 -1580 Analytical Report Fluorochemical Characterization of Surface Water Samples Pensacola, Fl (W2176) Centre Analytical Laboratory Report No. 023-014C (Revision 1) Revision Data 3/21/01 Testing Laboratory Centre Analytical Laboratory, Inc. 3048 Research Drive State College, PA 16801 3M Environmental Laboratory Contact Kent R.

3M Medical Department Study: T-6295.4 Analytical Report: FACT TOX-002 LRN-U2121 Study Title 104-Week Dietary Chronic Toxicity Study with Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) in Rats (Covance Study No.: 6329-183) Analytical Laboratory Report Title Determination of the Presence and Concentration of Perfluorooctanesulfonate (PFOS) in Liver and Serum Specimens of Crl:CD(SD) IGS BR Rats Exposed to Perfluorooctane Sulfonic Acid Potassium Salt (PFOS T-6295) Data Requirement Not Applicable Author 3M Environmental Laboratory Study Completion Date At signing Performing Laboratories Liver and Serum Analyses 3M Environmental Laboratory Building 2-3E-09, 935 Bush Avenue St.

& & S .6 - o e r if PFOS Pharmacokinetic - 000186 Corning Hazleton Inc.

6o/ R 2 6 _ PFOA Genotoxicity - / 000865 C O R N IN G Hazleton MUTAGENICITY TEST ON T6358 MEASURING CHROMOSOMAL ABERRATIONS IN CHINESE HAMSTER OVARY (CHO) CELLS FINAL REPORT AUTHOR Hemalatha Murli, Ph.D.

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