y}R,6_ 3W* 000410 RUM- TEFLON FINE POWDER/DISPEKSION OPERATORS C-8 BLOOD SAMPLE RESULTS C-8 in Blood (ppm) First Sample Second Sample Change 26.0 20.0 -6.0 24.0 25.0 +1.0 11.0 8.2 -2,8 9.4 7.9 -1.5 8.2 6.5 -1.7 7.0 7.7 +0.7 6.9 5.9 -1.0 5.6 4.2 -1.4 ..,,4.4 4.3 ; 3.9 4.9 +0.5 5.6 +1.3 3.6 -0,3 3.6 2.7 -0.9 3.5 2.1 4 2.9 2.8 -0.1 2.8 2,8 0.0 2.6 2.4 -0.2 2.5 1.8 -0.7 2.5 2.5 0.0 2.1 1.6 -0.5 1.6 1.5 -0.1 1.5 1.2 -0.3 1.3 1.1 -0.2 JWR:Idr/10/19/83 Bays Between Samples 363 364 391 364 363 364 337 334 365 401 364 362 363 357 365 391 336 349 288 384 366 362 % Per Year Change -23 +4 -24 -16 -21 +10 -16 -27 +13 +27 -8 -25 -40 -3 0 -7 -28 0 -30 -6 -20 -15 000411 TEFLON FEP OPERATORS C-8 BLOOD SAMPLE RESULTS C-8 in Blood (ppm) First Sample Second Sample Change 7.5 6.6 -.9 4.5 3.7 - A 3.1 2.8 -.3 2.1 1.5 -.6 1.8 1.1 -.7 1.8 1,6 -.2 1.6 1,4 -.2 1.25 1.20 -.05 1.20 0.95 1.00 0.79 -.2 -.16 0.86 0.75 -.11 0.75 0.72 -.03 '*i o 00 0.52 0.44 0.51 0.48 -.03 0.42 0.39 -.03 0.41 0.46 +.05 0.38 0.36 -.02 Days Between Samples 362 380 384 364 364 392 393 171 333 391 565 364 365 337 445 363 363 o p-i a % Per Year Change -12 -17 -9 -29 -39 -12 , -9 -18 -7 -8 -4 -15 -6 -6 +12 -5 JWR:Xdr/10/19/8.3 000412 SHORT SERVICE OPERATORS C-8 BLOOD SAMPLE RESULTS Fitie Powder Last Saoule PPM .02 .19 .93 4.00 *** FEP Days in Job 61 212 375 603 .05 95 .05 124 .15 135 .05 165 .23 492 .66 266 PPM Per Year Change +.09 +.24 +.03 - .18 +.15 +.10 +.38 +.09 +.24 -.24 JWRldr 10/19/83 000413 HEW HIRES - TEFLON Date of First Sample 07/28/81 10/01/81 10/07/81 10/13/81 Date Hired 'C-8 Blood Level (ppm) 07/27/81 <0.007 08/03/81 0.009 04/20/81 0.007 04/20/81 : 0.015 Months on Plant Before First -8 Blood Test 0 2 5 1/2 5 3/4 JWR:Idr 10/19/83 000414

- 3V- 7 A R .& Z6 - }lf 1 ORGANIC FLUOROCQMP PONDS IK BLOOD In May, 1978/ 3M informed Du Pont of findings of organic fluorocompounds in blood of employees exposed to long-chain perfliioro-surface active materials. 3M reported airborne contaminant levels up to 81 ppm in their operations and organic fluorine blood levels of 1 to 71 ppm for exposed workers. 3M reports that some level of organic fluorine in humans is normal/ i.e. equal to or less than 1 ppm.

ARag _ z x r g TSCA NCIC Notification Form for CBI Documents Docket Number: ______ f i l W h Document Control Number: Document Date: >Document Type: ______ e>o t r F ________ c ;.

LSL6- 0 6 lj- PFOS Medical Surveillance/Epi - t - 000023 Internal Correspondence August 2000 Memo to File re: OUS pooled samples Pursuant to a review of my file, there are raw data for several other pooled human sera sample results for PFOS dating from 1999.

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AR226-0(61 DT15 3M MEDICAL DEPARTMENT, CORPORATE TOXICOLOGY - ST-43: Standard Procedure fo r Liver Subcelular Fractionation - Study Objective: Perfluorochemical compounds such as perfluorooctane sulfonate (PFOS) have been linked with reduction in serum cholesterol levels and liver has been identified as the primary target site.

HAZLETON< * UABOPW CTDRIES A f W C A .

TECHNICAL REPORT SUMMARY TO; TECHNICAL COMMUNICATIONS CENTER - 201-2CN BACK TO MAIN Dale 8/31/81 (Im portant -- I f report sprinted on both sides o f paper, send two copies to TCCJ D iv is io n Dept.

BACK TO MAIN Analytical Data Summary PFOS, Primary Standard - Test Control Reference #TCR-00017-046 S o lu b ilit y in W a t e r , Na t u r a l S e a w a t e r , an A q u e o u s So lu tio n of 3.5% S o d iu m C h lo ride, and n-O ctano L with S ubsequent Calculation of the n-O c tan o l:Water Pa r t it io n Co e ff ic ie n t (KoW) of PFO S fo r each of t h e A q u e o u s Ma t r ic e s Author Mark E.

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AR226-1375 r PERSONAL g CONFIDENTIAL TO: C.

Northwest Bioanalytical Study No.

AR226-2164 Current Permit/Aocflcation/PDF tt 18234 &15D 01SD 1353A Pre-Exisunfl 614A 614A 781 153 2365A Note: For some vents me surfactant rate is less then the total particiiete reported In Air Emissions Inventory which can Include polymer dirsi Note: if emissions ere sen!

AR226-2373 ENOtNEERWS COMP'JliVfiON ............... ------------------------------- -- . --------------------------- * -- -1 ' .