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AR226-1377 Z-4t *CV 2*7 /waa.6_ 1377 E.

ENVIRONMENTAL ENGINEERING LABORATORY AQUATIC TOXICITY DATA SHEET TVP T e s t C M a t e r i a l T e s t e d f<2-9S~ O - f Z~g3 T e s t O r g a n is m ]*Iaa/QiJ /S iftfAjL A vg.

-AflUlo- Wildlife International, Ltd. -1 - Project Number 454C-107 DETERMINATION OF THE W ATER SOLUBILITY OF PFOS BY THE SHAKE FLASK METHOD ADDENDUM WILDLIFE INTERNATIONAL, LTD.

Fraunhofer ITEM Final Report 01 G 00 0 02 [Appendix E] 28 Day Repeated Dermal Contact Study of 3M Test Articles in Sprague-Dawley Rats Page 1 of 68 Appendix E: Histopathological Findings Fraunhofer ITEM Final Report 01 G 00 0 02 [Appendix E] 28 Day Repeated Dermal Contact Study of 3M Test Articles in Sprague-Dawley Rats Page 2 of 68 Table 1: Summary of histopathological findings (all animals) FRAUNHOFER ITA 01G0002 Summary of histopathological fi ndi ngs (all animals) Page: 1 21-Aug-00 !

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Modelinq - CAB - 5/7/03 Source ID 1 2 Description Pre-scrubber exit for fne powder scrubber (called "AC Scrubber11on map) Post-scrubber exit for fins powder scrubber (celled "AC Scrubber" on map) Location D Plant O Plant 3 DBC Scrubber 4 MP-2 scrubber E Plant; copolymer plant for PFA and FEP MP-2 building: copolymer type micro- powder Height, m 8 15 18.2 16.1 Diameter, m Flowrate m3/hr Flowrate. m3/min Temp 0.68l" 2400 40 100 c 0.6 9600 160 40-50 C 0.6 1820 27 40 C 0.6 assumed 7500 125 40 C assumed Compound C8 C8 cs C0 Emission Emission Rate, kg/br Rate, g/s 0.24 0.0667 0.24 0.0667 0.07 0.0194 0.125 0.0347 --------- . ... ........ {1) Given in email of 4/17/03 from Hldetaka Hiromatsu: 600 sq mm square dame er.

AR226-2747 WL Copies to: E.

AR226-2759 gnn nu POUT USE ONLY K I du Pont de Nemours and Company HHaasekke.llll ^U kiki mtono SJoad> TNeowkarlck>o lWDelaware 19711 " Study Inltiated/Completed 1/1/B - 11/3/ Material Submitted by c oiymer" rroduc.ts Dept.

AR226-2776 fINHALATION : EMBRRYO-FET-]AL TOXICITY AND TERATOGENICITY STUDY IN THE RAT HASKELL LABORATORY REPORT NO. 881-81 Company Sanitized.

AR226-2858 PERSONAL AND CONFIDENTIAL Copies to : u . .. , WE * 1' du Pon+ de Nsmours and Company H askell Laboratory fo r T oxicology and In d u s tria l M edicine HASKELL LABORATORY REPORT NO. 448-77 MR NO M a te ria ls Tested* Haste11 No. 1) 11,225 2) 11,226 Samp I es Ready For Testing 5- 6-77 L Materials Submitted bv __T e x t!

AR226-2881 Copies S- I. du Pont de Nemours and Company Haskell Laboratory for Toxicology and Industrial Medicine Elkton Road, Newark, Delaware 19711 ORAL LD50 TEST IN RATS lO^oun^adult'ch'R-CD^ale 2 S E * * * * " * intubation in single doses to 5 level for the U>50 study*.

AR226-2884 E.

AR226-2924 CENTRAL RESEARCH AND DEVELOPMENT DEPARTMENT HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE THE EFFECT OF PARTICLE OF A 1ATION TOXICITY INTRODUCTION . in this study nad been shown to be extremely tjoxic by inhalation when tested as a highly respirable aerosol (ALC of 4Z mg/m ).

AR226-3390 Comparison of Dose and Toxicity after Administration of a Fluoroalkylethyl Phosphate Surfactant by Dermal and Inhalation Routes in Rats C.