Fluoropolymers Monitoring Technical Group September 18, 2003 AR226-2338 ASH026929 ro coo CD o to oCD Agenda Program Overview - EPA Suggested Priority Change Discussion Landfills Soil Sampling Biota Sampling ASH026930 tHOo 00 o tMo o Possible Sources of Exposure ASH026931 HHN) a> No> APFO M anufacture Fluoropolymer Summary Processing * Articles of Commerce *- APFO Manufacture 99% Reduction in emissions as compared to prior manufacture Air dispersion modeling Water monitoring - Prior Manufacturer - New technology baseline Program Plant Design LOI LOI/other LOI TimmsrT * t * * In place Complete Ongoing Ongoing ASH026933 Ni HU) -CJO oHUOJ >99% E m issions Rduction APFO M anufacture A ir Dispersion M odeling Water Monitoring Fluoropolymer Summary Processing Articles of Commerce LOI ECA Non-Fluoropolymer Products Program Timing Commitment to not sell APFO outside fluoropolymer industry LOI Ongoing ASH026935 N>H01 CO o (J1 Eoi jOo (-* 01 ASH026936 >99% Emissions Reduction Air Dispersion M odeling Water Monitoring Fluoropolymer Summary Processing F luoropolym er M anufacture Dry R esin P r o c essin g Aqueous R esin P r o c essin g Articles of Commerce LOI ECA ^' IS> X Fluoropolymer Manufacture Program Timing Global Material Balance pre-LOI Complete 50% Emissions Reduction pre-LOI 2006 Commitment 2002 Status - 48% reduction from the baseline Monitoring/Modeling Commitments - Air dispersion modeling LOI 12/31/03 ASH026937 - Groundwater LOI/other Ongoing - Soil Other (Today) MCO COD H-J CO - Landfill Other (Today) >99% Emissions Reduction APFO M anufacture Air Dispersion Modeling Water Monitoring LOI ECA Fluoropolymer Summary F lu o olym er] cts Processing/Articles o f Commerce Program Timing Articles of commerce testing - "New" Articles of Commerce - "Aged" Articles of Commerce Dispersion processors material balance Incineration testing LOI ECA LOI ECA 12/31/03 2004 12/31/03 6/30/04 >99% Emissions Reduction APFO M anufacture Air Dispersion M odeling Water Monitoring LOI EGA Fluoropolymer Summary >50% Emissions Reduction Fluoropolym er M anufacture Air Dispersion Modeling Water Sampling/ Monitoring --------- ----------------------- Articles o f Commerce Testing Dispersion Processors Material Balance Aged Articles o f Commerce Testing Incineration Testing EPA Proposal Delay "Articles of Commerce" testing and goal date and accelerate "Air dispersion modeling" at Fluoropolymer manufacturing sites in order to expedite the process to determine if additional monitoring (and ECA) is needed at these facilities.

AR226-3204 DuPont-2925 Supplement No. 1 TRADE SECRET Study Title H-24000: Biopersistence Screening 10-Dose Oral Gavage Study in Rats Supplement No. 1 Laboratory Project ID: DuPont-2925 Author: Carol Finlay, B.A.

3M ENVIRONMENTAL LABORATORY REPORT NO.

ARa%-olHl 3M MEDICAL DEPARTMANT CORPORATE TOXICOLOGY To: John Butenhoff Andrew Seacat From: Marvin Case Date: 5 April 2000 Subject: Liver Slide Review I have completed my microscopic review of the liver sections of the 14-week sacrifice rats on the PFOS chronic study.

A R 1 2 C - 0 1 ^Attachments to Letter to C.

O Primedica Argus Division j 905 Sheehy Drive, Bldg.

AR226-1030A032 BACK TO MAIN Fluorochemical Decomposition Processes - April 4,2001 David A.

BACK TO MAIN DESIGN AND STRUCTURE OF MULTI-CITY STUDY submitted to 3M Environmental Laboratory 935 Bush Avenue St.

3M General Offices 3M Center St.

uaS" Estrous Cycling and Natural Delivery/Litter Observation Data FI Estrous Cycling Data, From Data Analysis Presented at EPA on August 30,2002" APFO Dose Group (mg/kg/day) 0 1 3 10 30 All 4-Day 14/30 19/29 9/30 15/29 15/30 Cycles 3-5 Day Cycles 24/30 26/29 21/30 25/29 27/30 Cycle Length (Days) 2 3 4 5 6 7 8 Mean Cycle Length (Days) S.D. 1 2 75 18 5 1 2 4.3 0.8 Incidence of Cycle Length Per Group 0 1 80 16 2 1 0 4.2 0.5 5 7 57 32 5 0 1 4.3 0.9 2 5 84 14 3 0 0 4.1 0.6 5 5 86 17 0 0 2 4.1 0.8 > 4 Days Diest. > 3 Days Est. > 4 Days Diest. > 3 Days Est. 2 17 5 25 Aberrant Cycles * Parental 11 13 15 FI 33 25 29 4 16 5 11 P E M D End in Estrous Distribution of Cycle Status at Start of 21-Day Evaluation Period, FI 14 12 8 10 11 14 62 2 0 15 13 16 13 Distribution Rats in Estrous at End of 21-Day Evaluation Period, FI 13 17 18 19 1 13 3 14 5 11 2 12 19 hO C-i; P '0 CD C--~5I I ro 2?

I Ok f t AKSLZG- 1131 REVISED DRAFT HAZARD ASSESSMENT OF PERFLUOROOCTANOIC ACID AND ITS SALTS U.S.

M&SL - 14-99 Review o f APME-Sponsored Kinetics I.

03/13/2003 10:06 oa/ia/oa os:09 UU DEP LEGAL SERUICES -> 915133010205 NO.129 304 026 8738 WV AIR QUALITY At.

AR226-1486 ENVIRONMENTAL AND HEALTH ASSESSMENT OF PERFLUOROOCTANE SULFONIC ACID AND ITS SALTS August 20, 2003 Prepared by 3M in consultation with Jack Moore, D.V.M., DABT, Hollyhouse, Inc.

ANALYTICAL METHOD VALIDATION FOR THE DETERMINATION OF PERFLUOROOCTANESULFONATE, POTASSIUM SALT (PFOS) IN PLANT TISSUES WILDLIFE INTERNATIONAL, LTD.