ARa%-03l8 REPORT EVALUATION OF THE ABILITY OF T-5869 TO INDUCE CHROMOSOME ABERRATIONS IN CULTURED PERIPHERAL HUMAN LYMPHOCYTES (WITH INDEPENDENT REPEAT) NOTOX Project 115943 NOTOX Substance 38196 - page l of 26 - Rfc-C&VED NOV - 9 1994 T"C/a O t--'O Oi \ 005605 T -5869 STATEMENT OF GLP COMPLIANCE NOTOX Project 115943 NOTOX B.V., 's-Hertogenbosch, The Netherlands The study described in this report was conducted in compliance with the most recent edition of: The OECD Principles of Good Laboratory Practice which are essentially in conformity with: The United States Food and Drug Administration.

CAS Number 4151-50-2 3M Company AR.AZGj&gO 1 Voluntary Use and Exposure Information Profile N-ethyl perfluorooctanesulfonamide I.

/IfttiG -cm R OCTANOUW ATER PARTITION COEFFICIENT TEST SUBSTANCE_____________________________________________________ Identity: N-ethylperfluorooctane sulfonamidoethanol; may also be referred to as N-EtFOSE Alcohol or FM-3422. (1-Octanesulfonamide, N-ethyl1 ,1 ,2 ,2 ,3 ,3 ,4 ,4 ,5 ,5 ,6 ,6 ,7 ,7 ,8 ,8 ,8 -h e p ta d e c a flu o ro -N -(2 -h y d ro x y e th y l)-, CAS # 1691-99-2) Rem arks: Material is an off-white, waxy solid.

Aime-wR 3M Company EPI-0003 Page 1 of 25 FINAL REPORT Epidemiology Medical Department 3M Company 220-3W-05 St.

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AR226-2084 1 DPotFuwroprooucts WPPAOARSK0H0SmXS1eU2rto1WH7iW, VoWn26102*1217 cc: Doug Anton KenLau Chris Gueris Sara Joslin .

AR226-2264 EID294840 Vapor Scavenging Coefflcent Liquid Precipitation = ______________________ Frozen Precipitation a C8 Particle Penalty *2 ,2 g/cm* Data Is based on tasting conducted atthe Washington W ort site In September, 1996.

AR226-2503 George Woytowich 0 8 /0 6 /2 0 0 1 0 9 :1 6 AM To: H David Ramsey/SE/DuPont@DuPont cc: Dawn D Jackson/CL/DuPont@DuPont Subject: Re: Lubeck Testing B l (1 ) Yes, 1992 data is. from the New Lubeck location

AR226-2977 FOR DU PONT USE ONLY Study Title Delayed Contact Hypersensitivity Test in Guinea Pigs with H-19173 Study Completed On July 17, 1992 Contracting Laboratory Pharmakon Research International, Inc.

ARZ%-ortH TOXICITY TO AQUATIC PLANTS (E.G., ALGAE) TEST SUBSTANCE Identity: Perfluorooctanesulfonate; may also be referred to as PFOS or FC-95. (1-Octanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8heptadecafluoro-, potassium salt, CAS # 2795-39-3) Remarks: The test substance is a white powder.

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AR50&-O3H0.

ACUTE TOXICITY TO FISH AR2T6-oS3q TEST SUBSTANCE Identity: Perfluorooctylsulfonate, didecyldimethylammonium salt; may also be referred to as Fluoroalkyl ammonium derivative. [1Decaminium, N-decyl-N,N-dimethyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-loctanesulfonic acid (1:1), CAS #251099-16-8] Remarks: The 3M production lot number was Lot 1.

fin 2 .6 _ O Z & TOXICITY TO AQUATIC PLANTS TEST SUBSTANCE_______________________________________ ___ Identity: A mixture containing perfluorooctanesulfonate; may also be referred to as PFOS, FC-95, or as a component of FC-206CF or FC-206CF-X. (1-Octanesulfonic acid) (CAS # 2795-39-3).