M22fce--toov DETERMINATION OF THE MELTING POM I7M ELTING RANGE OF PFOS WILDLIFE INTERNATIONAL LTD.

3M MEDICAL DEPARTMENT CORPORATE TOXICOLOGY ARUrO/50 To: Andrew Seacat 220-2E-02 cc: John Butenhoff 220-2E-02 From: MarvCase 220-2E-02 Subject: Pathology Review Date: 22 July 1999 On 19 July 1999 during my visit at Covance, Madison, I did a slide review of selected tissue sections on the PFOS six-month monkey toxicity study (Study 6329-223).

\ CAS Number 307-35-7 4i M _aT7<s Voluntary Use and Exposure Information Profile Perfluorooctanesulfonyl fluoride (POSF) I.

M 226 _ 077} ACUTE TOXICITY TO FISH (FATHEAD MINNOW) TEST SUBSTANCE____________________________________________ Identity: Mixture containing perfluorooctanesulfonate which may also be referred to as PFOS, FC-95, or as a component of FC-203FC. (1Octanesulfonic acid) (CAS # 2795-39-3).

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SPONSOR Elf Atochem S.A.

AR226-3189 DuPont-7326 TRADE SECRET Study Title H-25006: Bacterial Reverse M utation T est w ith an Independent Repeat Assay Testing G uideline OECD G uidelines for Testing o f Chemicals Section 4: H ealth Effects, No. 471 (1998); OPPTS G uideline 870.5100 A u th o rs Valentine O.

/\RJ2C,'018S oes^s PROTOCOL PFOS: A 96-HOUR TOXICITY TEST W ITH TH E M ARINE DIATOM (Skeletonema costatum) U .S.

M S M 6 _ O E S Zs MICROBIOS MICROTOX TOXICITY TEST TEST SUBSTANCE____________________________________________ Identity: A mixture containing perfluorooctanesulfonate; may also be referred to as PFOS, FC-95, or as a component of FC-206CF or FC-206CF-X. (1-Octanesulfonic acid) (CAS # 2795-39-3).

M AS 6 -ZHS ACUTE TO XIC ITY TO AQUATIC INVERTEBRATES (ACARTIA TONSA) TEST SUBSTANCE_____________________________________ Identity: A mixture containing perfluorooctanesulfonate, which may also be referred to as PFOS, FC-95, or as a component of FC-602. (1Octanesulfonic acid) (CAS # 2795-39-3).

AR226-1431 DR.U.NOACK-LABORATORIUM FR ANGEWANDTE BIOLOGIE 1-Decanol, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro- Effects on the Development of Caenorhabditis elegans in a Water-Sediment System acc. to T r a u n s p u r g e r et al. (1997) Sponsor Telomer Research Project Asahi Glass Cl a r ia n t Da ik in In d u s t r ie s Lt d Du p o n t RECEIVED OPPT NCIC 2003 July 18 1:09PM Author Gunda Winkelmann Test Facility Dr .U.No a c k -La b o r a t o r iu m Fr A n g e w a n d te Bio lo g ie Kthe-Paulus-Strae 1 D-31157 Sarstedt Laboratory Project ID Project-No. 020719CK Study-No.

Perfluorooctane Sulfonate: Current Summary of Human Sera, Health and Toxicology Data 3M January 21,1999 l 000014: January 21, 1999 TABLE OF CONTENTS EXECUTIVE SUMMARY............................................................................................................................. 3 I.

AR226-3046 Study Title Skin Irritation Test with H-21953 in Rabbits I .ahoratorv Project ID Haskell laboratory Report No. 790-96 Author Tracy A.

TRADE SECRET DuPont HL-1997-01294 AR226-3085 Study Title H-23004: Skin Irritation Test in Rabbits Laboratory Project ID: HL-1997-01294 Author: Tracy A.

AR226-3143 DuPont-3628 TRADE SECRET Study Title H-24256: Oral Approximate Lethal Dose (ALD) in Rats Laboratory Project ID: DuPont-3628 Author: Carol Finlay, B.A.