November 25, 1944 19 Dr .

Oc t o b e r 1 2 , 1944 Mr . 3 .

August 21, ly44 19 Mr.

TRANSLATION M i n i st er i o de Sani dad y A si sten ci a So ci al .

October 5, 1540 P r .

Up SHELL OI L COM PANY P.

J*: .^ Lead 2-ethylhexoate (also called lead 2-ethylhexanoate, lead <* -ethyleaproate, or lead "octoate*') is the lead salt of 2-ethylhexoie acid# (Its structural formula 1st Pb (oQC-CH-CHg-CHg-CHg-CH^) $ this vas given 2f incorrectly on the data sheet sent you by the Ministry of Supply) * It is a typical metallic soap (i*e* the salt of a metal and a fatty acid) and is insoluble in water, but soluble in certain organic solvents* It is not, in the strict usage of the term, an organolead compound, since its structure does not involve any Pb- C linkages, such as are present in tetraethyl- lead and in triethyl- and diethyllead salts* Also it is hardly conceivable that it could produce true organolead compounds, by chemical reaction* either in vitro or in vivo* As a lead salt of an organic acid| it is analogous i n m a n y ways to lead salts of inorganic aids, such as lead chloride, which are ionic in nature5 thus in ether, in which lead 2-ethylhexoate is soluble, it will tend to ionise as follows*- v- :

IN D U S T R IA L H Y G IE N E F O U N D A TIO N OF A M E R IC A , INC.

March 7, 1973 Mr. and Mrs.

IJovember 12, 1976 Stanley B.

IN TER-OFFICE CO RRESPO N D EN CE Et h y l Ga s o l i n e Co r p o r a t i o n Ch r y s l e r Bu i l d i n g 135 E a s t 4 2 Ni> St r e e t N e w Y o r k .

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