MEMORANDUM oe . _^<- DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE FOOD AND DRUG ADMINISTRATION T O George H.

ifetrch 5, 1973 M$* liarjorie &*K* Inservice Education Coordinator Edgamoor Geriatric hospital Horth Mgemoor Drive Santee, California 92071 Dear He* Briggsi Vour letter o February 6, 1973 to the attention of the Food and Drug Administration hm been referred Iso me for reply* We are at present cxapilta$ information on various talc products, but this is not yet ready for release* Inhalation of large rraomat of eshastee, a# in occupational exposure, is kno&tt to increase the incidence of lung cancer and pwseothelfossa, e&peeially in heavy sobers of cigarettes* Aabeafcos is often found- as a. natural contaminont of talc; both are magnesium silicates, end aro geochemicalXy Infcercoarvcriifele* Taleoei* if seaa only tmder conditions of heavy exposure and talc has not been demonstrated of itself to bo careino^onic* the levels of the various types of asbestos found in talc vary depending upon the source frm. which the talc comas, and: the use for Which it is intended, i.s* ties in heavy Industry, food UqpmUmdt, cosmetic* Generally* the bat-tar grades of commtc and food talcs are reportedly free of ae~ bastes* Iveadlcss to- ay, the suppliers and cotaaercial users of talc are aware of the potential problems presented cad in the last year or so the industry lias made an effort to reduce or eliminate asbestos in talc as required* Two statements from 1971 report on Asbestos by the national Acatoay of Sciences are of interest there are levels of asbestos exposure that will not he associated vlth any detectable risk.

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October l i , 1973 Ernest F , Fullam Associates P.

The Cosmetic, Toiletry and Fragrance Association, Inc. 1133 15th STREET, N.W..

h' April 26, 1976 T0: R.

INSTRUCTIONS FOR INSERTION OF "COSMETIC TALC" STANDARD INTO CTFA STANDARDS Attached are: 1.

I JVMOoaUlruyRmNAeAn1nL, NLOiueFmbAebieEir,R4IOn, cS1.O9, 8PL8uMbliEsDheIrCsINE nfant, child, and >r.Thejournai i?

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C olorado School of M ines R esearch P.O.

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The Cosmetic, Toiletry and Fragrance Association, Inc. 1133 16th STREET.

- -rl VjL ,iVi / A rAi lT\nT DEPARTMENT OF HEALTH, EDUCATION, AND WELFAR PUBLIC HEALTH SERVICE FOOD AND DRUG ADM INISTRATION TO : Henry E.