Document zzqXNpnQEen796wYb8kjBwrZa

St. Louis - General Offices May 27, 1964 Aroclor 1232' Federal Hazardous Substances Labeling Act Your Memo of May 21, 1964 R. Davis RD4VX Frank T. Nemlts Los Angeles Under the provisions of the subject act, Aroclor 1232 would be classified as a "toxic substance since its oral LDcq in rats la under 5 g/kg of body weight but more than 50 mg/kg. Similarly, the lethal dose when applied to the skin of rabbits is less than 2 g/kilo but more than 200 mg/kilo. The ranges Indicated above apply to those products which reach the market place in suoh a fashion that they are included under the Federal act. 1 cannot predict what the lethal doses would be for a formulation made up of 25 Aroclor 1232 in mineral oil. It la quite possible that they (the oral and skin lethal doses) would not be four times greater than for Aroclor alone. We have several indications that the Aroclors are more toxio when In an oil solution than when admin istered undiluted to animals. The ultimate responsibility for the proper labeling of a formulation remains with the customer since we cannot be expected to get animal data on every possible formu lation containing a Monsanto product. In all the varying concentrations and with the Innumerable combinations of other components suoh as antioxidants, colorants, eto. The very minimum precautionary statement that I think would be necessary would be: "CAUTION -- Harmful If swallowed. Keep out of the reach of children" EPWimJb Elmer P. Wheeler MONS 097865