Document zzqR9qpOrVexMY5E9RraBnGEa

PATHOLOGY LABORATORIES SURGICAL TISSUE-CYTOLOGY REPORT id. No. Ag Room No. Patient Doctor Data Submitted Date Reported INDICATED SOURCE OF SPECIMEN: #1. Periaortic lynph node #2. Periaortic lynphatic node GROSS DESCRIPTION: . #3 #4 #5 Periaortic lynph node Periaortic node Periaortic lymph node #1. The specimen consists of a small oval representing a periaortic lynph node. It has a rather tan appearing surface and maxinun diameter of 0.9 cm. Frozen section diagnosis "No definitive evidence of tanor". The balance of the tissue is submitted labeled! #2. Received in formalin are fragments of a periaortic lynph node used far frozen section. The fragments measure 7.0 and 1.0 cm. in diameter. The tissue is soft and tan. '* Frozen section "Fibrosis and' lynphoid hyperplasia. No definitive evidence of tumr". The tissue is submitted for histologic evaluation iakvi* #3. Submitted is a periaortic lyiqph node. . It is an of somewhat shixy vJhite and tan tissue v&ich has a maximum dimension of 1.2 cm. and a cross sectim diameter of approximately 0.5 cm. . < Frozen section diagnosis fcyj This tissue is submitted ' "Atypical lymphocytic infiltrate suggestive of lymphoma, diagnosis to be determined cn permanent section". .- ` #4. Submitted as periaortic lynph node is a paction of tan andvfcite tissue measuring in maximra length 1.7 cm.~a^ in maadsua todth. 0.7 cm. ' It is shijy witii^a'band of tissue resembling fibrosis at ' Frozen section diagnosis "Atypical infiltration suggestive of lymphoma, diagnosis to be determined by frozen section". PATHOLOGY LABORATORIES INDICATED SOURCE OF SPECIMEN: See Page -1- . GROSS DESCRIPTION: See Page -1- SURGICAL TISSUE-CYTOLOGY REPORT FINAL DIAGNOSIS: - . ...........* * " . #1. Biopsy periaortic tynph node: Wiwii/wvWMM .^ypiwpijgijr #2. Biopsy periaortic nfaaag^nwMiMi typexplasia. ............ - - - focal/ #3. Biopsy periaortic lynphnode: Sclerosing Balign^ lynph^ diffuse end nodular, ' . lyiqpfao-faistioc^^ . . *4. Periaortic soft tissue: ^falignant: lynftoa, sclerosing/ lyapto-Mstiocyt^ type. #S*;.y..Sa t tisv*s. u. e: Pibroadipos'e-***tissue art vascular doc.e. nt.s.. Note:. Material seat to^^^^^^^^^BMfn accsultation anifl PATHOLOGY LABORATORIES SURGICAL TISSUE-CYTOLOGY REPORT Id. No. Room No. Patient Doctor Data Submitted Data Reported INDICATED SOURCE OF SPECIMEN: ' . #1. Periaortic nodes'. #2. Aggeadix GROSS DESCRIPTION: The specimen is received in two parts. 79 Lab #1. Three distinct tan oval masses are received in formal in and range from 1.7 cm to 1.2 cm in maximal diameter. Qas largest when sectioned along its .long axis' appears to have a distinct fibrous ocopcnent. The other two have soft to moderately tan surfaces. Each mass is bissected and resulting fragments submitted for histologic evaluation labeled .<2 The specimen consists of a vermiform **"*'* with peri appendiceal tissue. The appendix measures 6 x 0.3 cm. This serosal aspect of the is smooth. . The lumen appears somewhat harrowed -iy near the distal end where it appears to be infiltrated by adipose tissue. Representative sections are labeled^ FINALDIAGNOSaS:; A ;V .. . , ..... .. #2.7 fentefiocmjeppnrtiift Sclerosing lyophoiiistiocyticlytqphamain adjacent soft tissue. . PATHOLOGY LABORATORIES 1. Left iliac crest GROSS DESCRIPTION: ' ^ 2. Right crest both rcm^||H^P Bane, marrow and 1. Two portions of coagulated .narrow material measure approximately 1.5^^ 1.7 cm in diameter and are disc like. They are submitted in toto labeled H|B' Also. received are portions of dark red inatwial in several small incresneH^averaging 0.6 to 0.4 cm in diameter. They are submitted fur decalcificaticn prior to . . . examination labeled 2.. Reaeived in fixative are swpw|1 =mall of magnlafpH marrrij mat-pri>] averaging approximately 0.6 to 0.8 cm'in diameter. They aze submitted labeled Also received in fixative are several fragments of. rather dark red material average 0.6 x 0.2 to 0.4 x 0.2 cm. The material is snbnrittpd SUBMITTING PHYSICIAN: r I L_ J cutNicAi. comments: The patient had a diagnosis of extradural poorly differentiated 1: ic lymphoma in 1965. Be recently presented-with ureteral obstruction and had a He now has multiple periaortic lymph nodes which were biopsied GROSS EXAMINATION: The specimen consists of 8 slides labele and 2 slides microscopic oEscRiRTtoN! Slide Sshows portions of a lymph node with reticuloendothelial hyperpl la and edema of sinusoids. vjPlasma are present In the lymphoid Infiltrates. Lymphoid cells and plasma cells are also present In the dilated sinusoids. In some areas, the lymph cells hrce extended into the perinodal fat. - ;! Sections also shows portions of a lymph node with reticuloendothelial hyperplasia and edem. of sinusoids. There are Irregular fibrous bands within the lymph node. In the adjacent/-:, flhrofat, there is a cluster of cells arranged in rounded nests. The cells are^suppo: ed by-a plexus of blood vessels. . the cells show sons variation In nuclear sire and stainln; X*a not certain as to the exact nature of cells but X favor the interpretatiad that> this represents a smallpaxagenglio*a.~~Tbere are small nerves associated yith the^ie^pn. Slide fpalso shows portions of lymph node and fibrbfat. The'lymph node shows a' pa'ttemrofy atypical nodular hyperplasia in which there are "atypical'histiocytes showing variation^inlv1 nuclear size and staining, j Xa some areas, the aggregates of histiocytes form interconnectec cords. The adjacent lymphoid tissue is composed of styplcallymphocytesthst have irragu!*? nuclear membranes.' Histiocytes are present in the adjacent lymphoid tissue. i The .nodal architecture is obliterated and the lesion has infiltrated thy adjacent flbrofat fbcally .deimsbplastic^;'5T^ '' Section ft also shows portions of. flhrofat and a lymphoid tumor.. The tumor has nodular qualifies-with atypical 'histiocytes in the. ill-defined nodules :hTbe lymphoid isfiltzi^a-ha Infiltrated flhrofat and is desmoplastic. The infiltrate has involved muscular veins snd ht produce^fibrous obliteration of the ..involved vessels. -: , -vSlideHHphon portions of lymph node and flhrofat. The lymph node showa reticuloendothc al hype^Tasia end preservation of architecture. The fibrbfat shows a diffuse infiltrate of atypical lymphocytes sad histlpcytas vith focal arses of desmoplasia. The desmoplastic char has Involved ~hlood . INDICATED SOURCE OF SPECIMEN: : V^'JSSfiSis^iS t IS