Document zzOEwq8EaMVvMvx6VdjEY9gz7

March 1*, 19k9 D r. F ran k H. C u t le r , 220 E ast S outh Temple, Sait- Lake C ity , Utah Bear Poetor C utler I have been a l i t t l e delayed in answ ering your l e t t e r o f March 2 because of th e n e c e s s ity of tak in g a t r i o out of to m . Meanwhile, ]io*tov e r , a s e t o f c o n ta in e rs w ith i n s t r u c t i o n s f o r th e c o l le c tio n of samples has been forwarded to you, and you should have th ese by the tin e you receiv e th is le tte r P ro a what you t e l l me ab o u t Mr. V H I H H H H V p , I would n o t suppose th a t he la s had any s ig n ific a n t exposure to te tr a e th y l lead in th e handling of samples of g a so lin e . I t i s , of co u rse, conceivable, th a t the g aso lin e had been handled so c a re le s s ly as to give r is e to some e x p o su re , b u t a p p a re n tly i t i s n o t g e n e r a lly a p p re c ia te d t h a t th e co n c en tratio n ' o f lead in commercial g a s o lin e s i s so low as to giv e r i s e to l i t t l e o r no le a d exposure on th e p a r t o f p erso n s who handle such g a s o lin e . In o rd e r to i l l u s t r a t e my p o in t I should say t h a t we have examined a la rg e number of re fin e ry and f i l l i n g s ta tio n handlers o f g a s o lin e . Sou o n ly have we n ev e r seen a c a se o f le ad p o iso n in g in such p e o p le , b u t we have n e v e r found any ev id en ce of le a d a b s o rp tio n among th e s e p e o p le . M oreover, we would h o v er ex p ect ro see a case of n e u ritis in any person exposed to te tra e th y l le ad , since even in frank cases of te tra e th y l lead poisoning, ro ta tin g to m anufacturing o p erations, n e u ritis has never been seen as a c lin ic a l re s u lt. In other words, te tra e th y l lead poisoning is d iffe re n t in i t s ch aracteris tic s from inorganic lead poisoning,and the c lin ic a l p ic tu re i s so d iffe re n t, in f a c t , th a t the usual type of illn e s s from the absorption of inorganic lead is not seen follow ing absorption of te tra e th y l lead. D e s p ite th e s e remarks#we have alw ays ta k e n th e p o s it io n th a t we should be on th e lo o k -o u t f o r any p o s s ib le d i f f i c u l t y , and th e re fo re I should be glad to give you any p ossible assista n c e in connection v ith the d iagnosis, and/or treatm ent of your p a tie n t, I t is w ith th is id e a in mind th a t I have sen t c o n ta in e rs f o r th e c o lle c tio n of Mood and 'u r in e , s in c e by th e ana ly s i s o f t lie s e sam ples we s h a l l be a b le to determ ine w hether o r n o t lie H fc- has had any s ig n if ic a n t exposure to lead compounds. In o rd e r t h a t I may c l a r i f y my sta te m e n t, w ith r e f e r e n c e to th e c l i n i c a l p i c t u r e o f t e t r a e t h y l le a d i n t o x i c a t i o n , I am sen ding you herew ith a r e p r in t of an a r t i c l e w ritte n on th is su b ject by one of ay a s s o c ia te s , which summarizes th e in fo rm atio n obtained by o u rselv es over a p e rio d o f y ea rs up to th e tim e th e a r t i c l e was w r itte n . Very l i t t l e u sefu l inform ation could be added to th is a r tic le a t th is tim e. C ordially yours, ME ef ob'erC'A.' K ehoe, M. d `.