Document zozNz63V7N9QkrqzkqKQDgboB

Monsanto Chemical CompanyoOrgr^ic Chemicals Division 800 North Lmdbergli Divd. St. Louis 66, Missouri CHEMICAL SPECIALTIES DATA REPORT Th information in this report was compiled to assist you in your evaluation and development of special uses for Monsanto products. Every effort has been made to include pertinent material bearing on the subject. This information is intended to guide your development work, but Monsanto cannot take part in the specific formulation or evaluation of any finished product.. .since knowledge of such should be reserved to yourself and is often your most vatuabte trade secret. No. Date cs-6 March, 1961. ttK.' ' MONSANTO AROCLOR* RESINS FOR INSECTICIDE FORMULATIONS A Discovery A simple method of Increasing the service life of expensive lindane sprays was developed several years ago by U. S. Depart ment of Agriculture scientists at their Beltsvllle, Maryland, testing station. The technique was to Incorporate Monsanto's "Aroclor" 5460, a resinous chlorinated terphenyl in the lindane solution. This pale yellow solid reduces volatility of thelindane -- slows it down to an effective, but not wasteful, evaporation rate. The result is an Insecticide deposit on treated surfaces that lasts up to ten times longer than that left by straight lindane solutions. Normally, simple solutions of lindane.leave a crystalline residue that dissipates within a few weeks. On hard surfaces such as glass, metal or painted areas, the residues last only about a week. Because lindane is a well established and effec tive pesticide, U.S.D.A. researchers sought a way to Improve the lasting qualities of lindane residues. Of numerous com pounds tested, "Aroclor" 5460 gave the best results at lowest cost. Test Work A major objective of these studies was to develop a suitable formulation for application to crops and other plants. Al though results under carefully controlled conditions were quite promising, subsequent tests by other agricultural ex perimenters gave only moderate success. Consequently, Interest has been slow to develop in agricultural circles. Apparently, the vagaries of sunlight, weather, and plant growth represent too many variables for effective study of the formu lation residues by direct application to exposed plants. * Aroclor: Reg. U. S. Pat. Off. 0539370 The Information In this bulletin is. to our best knowledge, true and accurate, hut all recomm.-ndiiunns or suggestion* Arc made without guarantee, since the conditions of u*e arc beyond our control. The **' 1 '*--------- nv liability incurred in connection with the use of Jjie*e data or suggestions. Furthermore, nothing romamed herein shall be con*trued as a recom mendation to u-** any product in conflict with existing paten!* covering ny material or its use. AD 70 TOWOLDMONOQ43666 o A New Idea But another pooalblllty for putting the U.S.D.A. discovery to work has lain dormant until recently; this Is the possibility of UBlng to good advantage the ability of ."Aroclor" reslnB to make the lindane adhere to smooth hard surfaces like metal, glass, painted areas, etc. This would consist of painting or spraying "Aroclor"/lindane formulations on such areas as the Inside of garbage can lids, on window screens, doorsllls, the painted walls of outbuildings, dairy plants, storage areas, etc.. In order to obtain lasting control of files, ants, roaches, sllverfish and other troublesome pe3ts. Suitable formulations can be readily packaged In 3hoe-polloh type "dauber" bottles, aerosol spray cans, and bulk packages for mechanical spray application. Development of this Idea 1b . based on the following: Advantages of U3lng "Aroclor" Resins In Insecticide Formulations * A suitable "Aroclor" (Monsanto makes seven) can remarkably extend the effective life of lindane and other chlorinated Insecticides as much as ten times (up to 2 and 3 months). * "Aroclor" -resln3 are very low In coot (around 20^/lb.). * Small quantities are sufficient (5 to 25 parts per hundred, by weight). * Formulation Is extremely 'simple -- the resin Is dissolved in a suitable solvent compatible with the Insecticide. * Stable In Inventory and in Insecticide formulation. "Aroclor" resln3 are fire-resistant, non-oxldlzable, non-corrosive, withstand weather extremely well. * Non-staining "Aroclor"/insect.lcide fllmB .formed when the solutions dry are practically Invisible. "Aroclor" 5^60 has a pale yellow color as supplied. Other suitable "Aroclor" products are nearly colorless. , . * "Aroclor" resins are odorless -- won't impart "chemical" odors. * "Aroclor" resins are safe to handle as long as they are not volatilized and Inhaled. They are practically non-volatile at ordinary temperatures, do not irritate or sensitize normal Bkln. . * The nature of the residue can be varied. Monsanto supplies a variety of "Aroclor" resins. These are chlorinated to various degrees and vary In physical properties as follows: Monsanto Chemical Specialties Data Report CS-6, ....Page 2 ' 0539371 TOWOLDMONOQ43667 Chlorinated Terphenyls Aroolor 5460 - yellow, transparent, friable solid (dries hard) Aroolor 5442 - yellow, transparent, 3ticky semi-solid (dries tacky) Aroolor 4465 - Yellow, transparent, brittle resin (dries Bticky) Chlorinated Biphenyls Aroclor 1262 - Light yellow, sticky, viscous semi-solid (dries sticky) Aroolor 1260 - Pale yellow, soft, sticky seml-solld (dries sticky) Aroclor 1254 - Pale yellow, viscous oil (dries "wet") Experimental Work and Formulations The following information wa3 derived from preliminary reports on work done by U.S.D.A. research groups. These data are not to be construed as recommendations by either the U.S.D.A. or Monsanto, but rather are Intended to serve as a guide or starting point for the development of private formulations. Fifty to 200 milligrams of lindane per square foot of surface has flven good Insect control on nonporous surfaces. The ratio of lndane to "Aroclor" 5460 has been varied from 1:1 to 1:4. For most purposes a 1:1 or a 1:2 mixture is satisfactory. Formulations as used In the U.S.D.A. experiments arc: 1) For application as a solution. Lindane 5 parts by weight "Aroclor" 5460 5 parts by weight Carbon Tetrachloride 756 parts by weight (Carbon tetrachloride is toxic and should be handled with extreme caution. Less toxic solvents are easily obtained.) 2) For application as an emulsion. Lindane "Aroclor" 5460 Xylene "Triton" X-100 (available from Rohm & Haas) 20 parts by weight 20 parts by weight 100 parts by weight 3 partB by weight To obtain a stable 1# lindane emulsion, mix 1 part by weight of the above concentrate to 13 parts by weight of water. Monsanto Chemical Specialties Data Report CS-6, Page 3 0:>3937^ TOWOLDMONOQ43668 o 3) For uae as a pressurized (aerosol type) spray. a) Lindane "Aroclor" 5**60 , Methylene chloride ' "Freon" 12 (DuPont) 3 parts by weight 5 parts by weight 40 parts by weight 50 parts by weight b) Lindane "Aroclor" 5460 . Cyclohexanone Oftho-dlchlorobenzene "Freon" 12 (DuPont) 5 parts by weight 5 part3 by weight 10 parts by weight 35 parts by weight 45 parts by weight iI Experimental Results American Roaches Using Formula 3a or 3b, the toxicant was applied onto a painted wall, depositing about 200 mg./sq. ft. of lindane and a like amount of "Aroclor" 5^60. When the toxicant coat was one month old, it gave 90-100$ kill of American roaches when the roaches contained in a petri dish were placed against the surface of the treated wall for two hours. - The U.S.D.A. research team found that the lindane-"Aroclor" 5460 mixture (used at the rate of 50 mg. of actual lindane per sq. ft.) would kill 80$ of all cockroaches exposed for 2 hours to a 60-dayold treated surface. It remained lethal to 66$ of the roaches after 90 days. Regular lindane sprays used at the same rate killed only 4$ of the roaches after 6o days. Results with Houseflies Deposits of 25 mg, of lindane plus 25 mg. of "Aroclor" 5**60 applied from carbon tetrachloride onto glass and aluminum (hard surfaces) gave 100$ kill of normal houseflies exposed for 2 hours to these treated surfaces after they had aged 18 weeks, the duration of the test. Without the "Aroclor" the hard surfaces treated with lindane alone were effective only about a week. A lindane plus "Aroclor" mixture sprayed as an aerosol onto leaves of a willow tree continued to kill houseflies after 2 months of outdoor weathering. Careful inspection of the treated leaves showed that the toxicant was held firmly to the surface and notwithstanding rain and weather, the coating re mained in good condition. Also, within limits of a preliminary inspection there seemed to be no injury to the willow leaves. Monsanto Chemical Specialties Data Report CS-6, Page 4 0539373 TOWOLDMONOQ43669 (Notes The primary purpose of this report is to provide in formation for the development of suitable insecticide formula tions for application to "nonsensitive" surfaces Buch as metals, glass, paints, and other materials that will not be damaged by the application. Development of formulations for living plants requires sufficient test work to insure that the formulations will not be injurious to the plants or their products.) Another Formulation Reported A more recent development in these experiments is the following simple formulation: . "Aroclor" 5**60 25# Lindane . 25# Methyiethyl Ketone (MEK) 50# Work on this was reported in the August 1*1, 195** issue of Chemical Week magazine. This simple formulation appears to be most suitable for "painted on" formulations packaged in bottles but should be used with caution in mechanical spray equipment since the MEK solvent will soften rubber and certain plastics. The formulation could also be modified easily for aerosol packaging. Since MEK evaporates rapidly, it should not seriously affect painted areas unless too heavy applications are made. The package label should include a caution to this effect. Also, MEK is flammable. Possible substitutes that are less flammable are methylchloroform or a mixture of methylchloroform and methylene chloride. Formulating Other Insecticides The beneficial effects of "Aroclor" 5**60 apply generally to other chlorinated insecticides including chlordane, aldrln and dieldrin, but do not apply to phosphate type insecticides Buch as TEPP, parathlon, methylparathlon, malathlon and chlorothion. ' . ##** For samples of the "Aroclor" products mentioned in this report, contact the nearest branch office (see attached list) or write to: MONSANTO CHEMICAL COMPANY Organic Chemicals Division Plasticizers Department 800 North Lindbergh Boulevard St. Louis 66, Missouri ' Monsanto Chemical Specialties Data Report CS-6, ....Page 5 0S3C374 TOWOLDMON0043670