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AR226-1971 PERSOMM. AMD COHFIDEMTIAL 'S. CC: L. F. Percival - Wilm. J. G. Loschiavo -? April 7., 1981 TOi FROM; C. R. CAMPBEIA J. F. DOUGHTY "D. A. ERDMAN L. W. GOIN DR. Y. I,. POWSR T. L. SCHRENK PAUL TOISTLETOH ^ft u AIRBORNE-.C-8 COMCEin'RATIOM AMD ORGANIC FLUORINE IKT BLOOIT SAMPI.ES The attached table was prepared to answer a question by He aI .skAed, Lundgaard which was relayed by Lance Percival 4/3/81. if there was a correlation between airborne C-8 and organic fluorine in blood. There is not a direct correlation as with some materials where an exposure ona day may appear directly or as a metabolite in the urine the next day. C-8 accumulates in the blood and is not readily eliminated from the body. Therefore, .organic fluorine in blood samples is usually the result of exposure over an extended period less elimination which may vary between individuals depending-on differences in body chemistry. The data for monomer operators illustrates the persistence of C-8. Seven long-service monomer operators who may have been exposed to airborne C-8 had an average -organic fluorine level of 0-35 ppm in their blood which is the same as .the background level for 'organic fluorine given in the answer to question 17 (". . . organic fluoride blood levels ranged up to 0.4 ppm."). We do not know if this was naturally occurring organic fluorine or C-8. Three monomer operators.who had about 2 years monomer service preceded by 15 years fine powder service had an average organic fluorine level o'f 5,9 ppn in their blood. This must be a carryover from exposure in their fine powder assignments* The level is similar to current fine. powder operators who had organic fluorine in their blood samples ranging from 0.2 to 21.7 ppm. . Attachment i PT/nsw EID080710 TEgI.OKg) DIVISIOMS AIRBORNE C-8" COMCEy^TIOM aND ORGANIC FLUORINE IN BIiOOD. SAMPLBS gREa. MONOMER ABBA (1) SAMPLES AVERAGE -C-8teto 0.4 - FINE ECMDSl BolynccLzation 0.7 ' Finishing' 1.4 QRSQTC msxaaas. m BCOOD saMEii^ (2). MOiaBER SSMEUB) ^(3) 3^ . AVERAGE ' S5KBS , . IN vaEwm"' - BaHGE 'POTI -- -- 24 0.1 - 0.5. 17 5.3 - 6.7 AVERaSB 0.35 5.9' 18 . 14 10 0.2 - 21.7 7.0 7 0.5 - 5.0 2.4 ETSP . Polynerization 0.7 13 21 0.9 - 5.0 2.8 (1) 'faken between October, 1979 and tfarch, 1980.. (2) Taken .in August, 1979. (3) long service nononer operators. (4). Short service 15 - 16 years moncnier operators (1-2 in fine powder area. years); previously worked (5) Bbte ~ these are total years in Teflon. Many people had. several assignments with different C-8 exposure potential. PI fe 4/7/81 g EID080711