Document zobZVM7amj7gk0XqaaGNMEvxn

fE'.FPHCNE HUDSON -i i i>, Manufacturing Chemists' Association, Inc. (FOUNDED 1B?2 1825 Connecticut avenue. N w Washington. D C 20009 OHC-14 OCCUPATIONAL HEALTH COMMITTEE Minutes of Meet ing MCA Offices, Washington, D. C. September 14, 1967 PRESENT C. U. Dernehl, M.D., Chairman E. E'. Christofano Mac Roy Casque, M. D. F. D. Gassavay, M. D. N. V. Hendricks M. H. Johnson, M. D. G. J. Levinskas W. J. Martin, M. D. W. E. McCormick R. U. McNab F. L. Oglesby J. A. Pendergrass G. J. Stopps, M. D. J. H. Wolfsie, M. D. F. G. Stephenson, Secretary Union Carbide Corporation Hercules Incorporated Olin Mathieson Chemical Corporation Gulf Oil Corporation Standard Oil Company (N.J.) Monsanto Company American Cyanamid Company Cyanamid of Canada Limited The B. F. Goodrich Company Wyandotte Chemicals Corporation Tennessee Eastman Company Minnesota Mining and Manufacturing Company E. I. du Pont de Nemours & Company Uniroyal Manufacturing Chemists Association GUEST W. L. Sutton, M. D. Eastman Kodak Company ABSENT E. M. Dixon, M. D. T. R. Torkelson Celanese Corporation The Dow Chemical Company < l l,- I,, .L 2. Medical Management Sections of Chemical Safety Data Sheets Ji kW 1 CMA 012810 BFG53157 o(VI o 0 CD 0HC-L5 (h) Ethvlene Dichloride - (author Dr. C. U. Demehl) wl II n I. ij BFG53158 CMA 012811 OHC-16 4. Epidemiological Study Mr. W. E. McCormick reported that The B. F. Goodrich Company article on Occupational Acroosteolysis had been published in the Journal of the Americal Medical Association. Copies will be distributed to consnittee members. The research program at the University of Michigan has been slowed be cause of unavoidable delays in visiting plants and in obtaining x-rays. MCA's contract has been extended to December 31, 1967. A report on the reading of each x-ray submitted to the University will be sent to the plant involved. lp,r CMA 012812 BFG53159 o coo o \ 6 r/ % 13 Cl o BFG53160 5' i 7 TELEPHONE HUDSON )6i;c Manufacturing Chemists' Association, Inc. (FOUNDED 1872 i 1825 Connecticut Avenue. N w Washington. D. C. 20009 OHC-22 OCCUPATIONAL HEALTH COMMITTEE Minutes of Meeting Offices of 3M Company, St. Paul, Minn. May 26, 1568 PRESENT C. U. Dernehl, M.D., Chairman E. M. Dixon, M.D., Vice Chairman Mac Roy Gasque, M. D. W. J. Martin, M.D. R. W. McNab F. L. Oglesby J. A. Pendergrass G. J. Stopps, M.D. T. R. Torkelson J. H. Wolfsie, M.D. F. G. Stephenson, Secretary Union Carbide Corporation Celanese Corporation Olin Mathieson Chemical Corporation Cyanamid of Canada Limited Wyandotte Chemicals Corporation Tennessee Eastman Company Minnesota Mining and Manufacturing Company E. I. du Pont de Nemours & Company The Dow Chemical Company Uniroyal, Inc. Manufacturing Chemists Association GUESTS W. A. McClellan (representing F.D. Gassaway,M.D.) E. L. Jaffee Gulf Gil Corporation Manufacturing Chemists Association ASSENT E. E. Christofano N. V. Hendricks G. J. Levinskas M. N. Johnson, M.D. W, E. McCormick Hercules Incorporated Standard Oil Company (N.J.) American Cyanamid Company Monsanto Company The B. F. Goodrich Company 25014032 / .2 Epidemiological Study Dr. Dernehl reported on the status of the study. The contract with the University of Michigan has been extended to a completion date of September 30, 1968. CMA 012813 I BFG53161 C C O VTO SZ BFG53162 TELEPHONE HUDSON . - Manufacturing Chemists' Association, Inc. ( FOUNDED 1872 t 1825 Connecticut Avenue. N w Washington. D. C 20009 OHC- 2 6 OCCUPATIONAL HEALTH COMMITTEE Minutes of Meeting Executive Inn, Louisville, Ky. October 23, 1968 PRESENT C. U. Dernehl, M.D. Chairman E. M. Dixon, M.D., Vice Chairman E. E. Christofano M. R. Casque, M. D. N. V. Hendricks M. N. Johnson, M. D. G. J. Levinskas W. J. Martin, M. D. V. A. McClellan, M. D. (representing F. D. Gassaway.M.D.) J. A. Pendergrass G. J. Stopps J. H. Wolfsie, M. D. F. G. Stephenson, Secretary Union Carbide Corporation Celanese Corporation Hercules Incorporated Olin Machieson Chemical Corporation Standard Oil Company (N.J.) Monsanto Company American Cyanamid Company Cyanamid of Canada Limited Gulf Oil Corporation Minnesota Mining and Manufacturing Company E. I. du Pont de Nemours & Company Uniroyal, Inc. Manufacturing Chemists Association GUESTS A. L. Potter, M. D. F. P. Shepherd, M. D. Imperial Chemical Industries Limited (Chairman, Medical Committee Chemical Industries Association) E. I. du Pont de Nemours & Company ABSENT W. E. McCormick R. W. McNab F. L. Oglesby T. R. Torkelson The B. F. Goodrich Company Vyandotte Chemicals Corporation Tennessee Eastman Company The Dow Chemical Company m r\I.T T v P ^ -- % tHifti UtiiKu' irti Chfit 0I2S14 BFG53163 3. Epidemiological Study Dr. C. U. Dernehl reported on the status of the research program being carried out at the University of Michigan. It is anticipated that the final report will be made early in 1969 at a meeting of the Occupational Health Cooxnittee, manufacturers of polyvinyl chloride and representatives of the University of Michigan. It is understood that subsequent to the presenta tion of the report additional presentations will be made to the American Medical Association and the American Industrial Hygiene Association. Dr. Potter reported on investigations of the phenomenon which are taking place in England. s e n i'in e z BFG53164 CMA 012815 014036 CA BFG53165 MANUFACTURING CHEMISTS ASSOCIATION *825 CONNECTICUT AVENUE. N W WASHINGTON. 0. C. 20009* 1202) 483-6126 OHC-30 OCCUPATIONAL HEALTH COMMITTEE Minutes of Meeting MCA Offices, Washington, D. C. April 30, 1969 PRESENT C. U. Dernehl, M.D., Chairman E. M. Dixon, M. D., Vice Chairman E. E. Christofano G. J. Levinskas W. J. Martin, M. D. W. A. McClellan, M. D. W. E. McCormick R. W. McNab F. L. Oglesby G. J. Stopps, M.D. T. R. Torkelson J. H. Wolfsie, M. D. F. G. Stephenson, Secretary Union Carbide Corporation Celanese Corporation Hercules Incorporated American Cyanamid Company Cyanamid of Canada Limited Gulf Oil Corporation The B. F. Goodrich Company Wyandotte Chemicals Corporation Tennessee Eastman Company E. I. du Pont de Nemours & Company The Dow Chemical Company Uniroyal, Inc. Manufacturing Chemists Association ABSENT Mac Roy Gasque, M. D. N. V. Hendricks M. N. Johnson, M. D. J. A. Pendergrass Olin Mathieson Chemical Corporation Standard Oil Company (N.J.) Monsanto Company Minnesota Mining and Manufacturing Comp 2. "Epidemiological Investigation of the Polyvinyl Chloride Industry in Reference to Occupational Acroosteolysis" - discussion of University of Michigan report. The Chairman stated that the subcommittee had met several times with repre sentatives of the University of Michigan and had discussed drafts of the report. It was agreed chat it would be submitted to the Occupational Health Cotnnittee prior to its submittal to manufacturers of PVC on May 6 in Washington, D. C. The Chairman asked if there should be a further study project on acroosteolysis. Dr. Magnuson will be prepared to discuss this on May 6. The present study is only a prevalence study. Little is known of how the disease starts or develops or even of the transient incidence of Raynaud's phenomenon. The recoomendation for continued surveillance of PVC operators is important since It will provide valuable information. Mr. McCormick regretted that the report does not include a footnote to ex plain case Dx 4 on page 101 which lists an incidence of Raynaud's phenomenon occurring in compounding, and that the word "probably" on page 67 was not changed to "possibly." BFG53166 25011037 OHC - J1 These changes had been agreed Co but were noc made in the finaj.,draft reporC. che Dr. Wolfsie found che report generally acceptable. The cotnniccee, he thought, should now make a definite recomnendatlon to the manufacturers regarding further activities . Dr. Dernehl reviewed the findings that the disease occurs among vessel cleaners -- that che causative agent was not definitely identified -- that most cases show a combination of Raynaud's disease and bone changes -- and that bone changes are almost indistinguishable from those resulting from traumatic injury. Mr. Christofano questioned the reconsnendation to reduce vinyl chloride ex posure to 50 ppm. There followed general discussion of this recomnendation. A MOTION to accept the report as submitted was then defeated by a voce of 7 to 3. After further detailed discussion the comnittee VOTED unanimously to accept the report, subject to the following changes in the RECOMMENDATIONS which appear on page 104; (a) RECOMMENDATION I - Page 104 of Report Eliminate the last sentence "Where it is necessary for workers to enter the reactor tanks, sufficient ventilation should be provided to reduce the vinyl chloride concentration below 50 ppm." / Insert in its place "Where it is necessary for workers to enter the reactor tanks adequate ventilation should be provided. Inasmuch as the etiologlc agent of the disease is unknown, a level of vinyl chloride below 50 ppm should be used as an index of adequate ven tilation." RECOMMENDATION 3 - Page 104 of Report "supported" Change word "continued to The cotnnittee then resolved to make additional recomnendations to the vinyl chloride and FVC manufacturers: (a) There should be pre-assignment examinations of vinyl chloride and polyvinyl chloride production workers. These examinations should include: I. Hand X-ray II. History - including that of Raynaud's disease, scleroderma and abnormal cold response. (b) There should be periodic surveillance examinations. These examinations should be given at least once a year and should include: I. Hand X-ray II. History - as above BFG53167 S E atinr? CMA 012817 OHC-32 1 Further studies of the disease The conmittee recommended that manufacturers of PVC should sponsor further studies of the disease and its causes and chat such studies be under the super vision of the Occupational Health Committee. It was further recommended that the conmittee chairman write to Dr. Magnuson at the University of Michigan and congratulate him on t e successful conclusion of the project and on the excellence of the report. I fv.-. :: 25011039 BFG53168 CMA 012618