Document zoMJxMgwdeL0q9qRRe1dDGMym

Baile we as -- - x [natnlhmas icvdri BrinBfecm rb 1,1,1,2,3,3-hexafluoro-3-methoxy-2(trifluoromethyl)propane Cermber2107 Case Er -- | PBT assessment Administrative data PBT assessment: overall result f"rRoefmerence SoEwEeno a. RP -- srt he | toe scr sei sora enrameinar8T08 erarannn ironnbB.tetTswssctaregeensootfcm+ eogoftimnatrmirantScoounripoiwwehr EnoorevvaSnresasntsntowe3 SLECHA TFEiacurotieannisnafeto :sGpotonnofo ttoernw ry ibedr1e ocosaosn tsUy no rrornvonsoy ori om vt) btn i ok allie ERSTRITEATIRT, ASE = a Er -- * tis e tomato ct copy sd si einof crf sft,dso 1,1,1,2,33-hexafluoro-3-methoxy-2- (trifluoromethyl)propane Gombe 22702 CAs | Eves aays 9 Phototransformation in air 01 Key Epona Administrativedata pone Tonal Manaus ommerematonsnn epementsy hors Datasource -- Rtv syn ae rare pana I Matearndimeathlodss. Testgains - utr [rr-- oo Sevtons tsetse Test material Consent - = } Stuydesign Lapses a Results and discussion [ER ---- ors wor Applicants summary and conclusion glomtuin Iran oanriRniTohseSubstarcescoa0msefoomnegrneetmoddoossehowmhceh Ain or orc ot SstCosa whapd 1owwenissot 0) 9000 be+ ELE CEAA ReEAcCoHnRessincTo chaarrgwona rsttoeeor fd pn 090 aby Deormmaointnvmoastmarraan,t ntoenof efronanmnaetbn)sffac pcoepnlpmct.gUeeofle Bailie RREARATFACSI, BERNAL . Ee --_-- - x sch st coe mepi 3 rfpn ic 1,1,1,2,33-hexafluoro-3-methoxy-2(trifluoromethyl)propane Corse 117 cht Emmett rons oHtyderrorlpysrimsettreni Administrative data -- [on recta wim Jorn psy Data source = fone wren nse pe Materials and methods Testguideline cQuualtteer. ome 7 C`ae ccoordingdto guiOa delrineg. ansso= minien " Test materi content `Testmaterialinformation oo hs Results and discussion fr [-- "Totalrecoveryoftest substance(in %) oo DspDTSaprietocompnosed ors i oe tspctes Applicants summary and conclusion Ilooruamt1toosnnnnonerSotsTehdScSerubsttatcaesooca0+mspefsonmnesoetrnagenarddoosRosegwriehr 1 b8reubo0nn0s0dt0n8 EEA TRReEcAeCoHRcetemo)itToteidlaogrtteotonanotfotputsr on, ond ton may ff 3 otc 1osoh, sccop prt. eof Iainawit h an 0 ae om hun) ot pcos mani i Bailie RRA, SERBSwe a _-- -- f tai t man ctrl ie pen feo of rn AS 1,1,1,2,33-hexafluoro-3-methoxy-2- [Er] (trifluoromethyl)propane Sonmtm 2207 Gas Entcomenattte stways 0BiKoedyeEgramdaitiron sin water: screening tests Administrative data Cr roto Manet, Satohainn gs epimers tony Datasource tren rete yon roe mart onan I Matearndimeathlodss Testguideline at cute I stn ution 0C5E0rGiueirnan010 syBunn Test material | Testmateral information oo Contr Studydosion omens seabe cheno: com: t-onto 180 tet steoceton Initialtestsubstanceconcentration 1 nsdn sm Initialtestsubstance concentration 2 [--- soraon. Results and discussion pr-- Degradatio1n Pum do 02 cot nsumo) vote: 2 Stngime 2a [-------- Degradation2 | Parmeter cogadtonstmat aay) ake: a Smoegine 29 t Renssasornis ove Degradation pune: pain 02ssp) ave: on smougine ma [a ------ Degradatio4n pe cuca wen a songs 24 stmt. sna) `Applicants summary and conclusion yc ott yer elgortmtataonnamnaengeteTnhdStsisbgsncmeenscofom8emsfgoseymsrnddosns rhoWincehbnavgsuveanne5s dve E@EECCHEUAA RfEAaCmHaRagitnh)dToisrcraarieotn t1h0 enosreiardpavawdibye0gAgr(EoCf) ooy 19t07a2t06t(yho Tphercoocrhtee s oFrdchiunt gnwoif tps leiee mybe suc opr pectin,Usof etormiastootbooorm,aso prison om he own) of resco aonmhvote ania EAA, AER -- a wn - * itn toe seo nf mn 11,1,23,3-hexafluoro-3-methoxy-2(trfluoromethyl)propane A [Rr ag Biodegradation in water and sediment: [ET ------ simulation tests Administrative data fo Sm etonmsiege Cousteaee Crossefeance1 . vnnipmun danvan sping man | | Retrence pon Sonn ty pesto smote Antsy ey at: JR ca icohn10aes i Sinn st - | eons see | octet: oc o=ns oms 83 [J -- | btn -- saacionn: J ---- S07mgn. Spr acme) | sine r-- fn te ovine rms [a -- [ROS reacts rane ae gto rion cu 280 JO---- an a Sreprott rnp Sartre - wo) ata ov Crosssttence2 nts amo stor te peste `Endpoint: cota b Here'slowconstant - Jomtien ant setts sven w ican ns: we nr oo Data source Materials and methods Results and discussion Applicants urmmary and conclusion etmoaamtraotnno nsneorRdeesgTehdscSeavaeecrtofcda3misscmn(pansihraotnsddiooherBresogwawneircsh(oh5tv)epbi0ee2sa0sm8aadve+ SECHA TRoEaAcCiHtReepti),aTchtoschegeawshoohaa etrroorsdeid Apne os oeactor eSfororsauttmwhooavhcarain topnTof us fomaOnncmvyb)eSofcstpeocpr fapmrcation sifh eatin = mT, AERA Ee Am - = it lem crisdy en 1,1,1,2,3,3-hexafluoro-3-methoxy-2(trifluoromethyl)propane Corbi 307| Cxtmter Enoomentat tsuneo aB0ioacgcuutmeulEataimoan:ieaqsudattic / sediment Administrativedata [ove Serotec J Metin catos mye ai bst ncoos Data source Reference. eee oe | peas - satya pa 6 0 orn [==] Matearndimeathlodss tent gudeion pe Cotto fa sieges | S6oDpetttBne0r5emncFlmiTatn nu Test materi |Testmateria information Cost rons 0 Test organisms Tesesc pcan Studydosign [oP --" Tettpe: tomtronn jitseert tsst Taopepe 309 Test conditions rCoeatsetst Results and discussion thdcamen [oT -- ae nots a [---- | Bioaccumulationfactor1 i oe va: [. Tes | contmntes | rescore oer 51s sot 2 nen om: `Bioaccumulationfactor2 ve a Tov Cost 70s amos wit 2 soaps | Depuration - |eva - Applicants summary and conclusion roa 1 lmeaaattotn oaoeBoeTgros scsoraser sotctowecaofnsinecpoamrpsoant odosseesvherh gto phovenetssteadve 00 SLECHA TEecAaHnectpsoif)kcTrtoc cenmfm c01frbroa rtnsndn bt 2c0p cpr e cineUo t eoofy am rao toedcos 9 Rn fewrt) nc ho ms Ballims RRNSARTARTIAT, SERS - Ee ae x nSfemaain 51cop mts isn 1,1,1,2,3,3-hexafluoro-3-methoxy-2- (tifluoromethyl)propane Conte cri - Camber Entonmert sss 9 Adsorption /desorption Administrative data Cos erin erws natant weit [AIP Data source Reference So ate an ph. tart Yr - sain wo of oto rbd Materials and methods aauunt Testguideline. Tvtmnet es I prr------ GCn Eoeinn a ooGmheOavrennssom wmSin n Wo nme - Test matt Testmaterial formation content Results and discussion pr-- Adsorption cosfcient1 oe ro we su `Adsorptioncoefficient2 oe pos me 258dmamiiss Applicant's summary and conclusion eI5Wevmiactonnmounmbfa tThdeosssgecmenet ofce8 sga(e5nmoenmpsoorndsrsrhsowwehoaBmgusoensrettdtsn CEHEEECETAAL RfEoAmCaHteilntnothne)dToh rfocromraesctohrstrho edsns ecdhvsidhbehgoAg (o5fNnoyo13t072s60c0rh Tpfhoermcoaatcroetnnoarhcofutuhriaadchningae mnpiosof thnrsetfrforatmmaethioenomwaynb)o ifcntrs10pcctonspylpoeaintUhe ovft weofeos wre, artim: HRSAT T, SERR NA ws ax -- an x term ss or ssBp 1,1,1,2,3,3-hexafluoro-3-methoxy-2(trifluoromethyl)propane Ecmmtac am| cases Comiogctitormin 13) Ecotoxicological Summary Administrative data Hazard for aquatic organisms Freshwater a Vata eco J---- Enpssames Ea oss ssn Marine water =-- rca soma [-- emmcnnnos smote: sw H-- essen roma9enecsts Sediment freshwater) Wasson Css sons) eco: oxvsmanssesmeten Crmnened epost Sediment(marinewater) rxotssirrs RSsede rnme) ca a0r2mgngsmcon [Er -- Hazaforraidr Ar roves eo oflti a Hazard for terrestrial organisms sail [Ipuscatn necane Exposes ---- us rongssn cinsta eos Hazard for predators Secondary poisoning Nard topenitorboscmiotan Additional information Conclusion on classification formattoionnoonrReegToeenseSsstnes cams erienrgeotcdoosresvWesh1harepbienn1v3ndve+ EECA RCcAmCeana)oe.5To4f1 caoica o3tbeonetenComvparnwibhyRiAtgo(5a)soc19e6t72s00r6(hyo TRbhecmonnnrwoihrtcotaSichoaimtsp opioufettphsffeormcanowmnbe8rS)5bs01sppcT opmraenciomUvs fohte fopimiispase Ballin - EARSTATFASIAN, SEEMS w= oa mt Rett rant cto ys dy hin hc of frit dete 1,1,1,2,33-hexafluoro-3-methoxy-2(trifluoromethyl)propane er ame Crt. Toteoagestntamasen A Toxioologiont summary Administrative data Worker-s Hazard via inhalation route Systemic effects Lngtem ene = tse sora J, ~ Nets roves ove fmaten Losalafects Lote eponse -o_t-- a soviet Aes amrpoien tercrnen rotons ovbtm Workers - Hazard via dermal route Systemic effects tgmepn_ etwas romania oo Rees mesons rmdir rovpsdiontes ONE btn Localefects [res-- Vets rovoniinted Aosta posse Workers - Hazard for the eyes Local efects Varstssssimert rohuzdicrtied Additional inform-awtorikoerns General Population - Hazard via inhalation route Systemic effects: tongum posse Varsssssimert nohadicetied Restrnt tm expose Varsdsusrimet nobandidntied Localeffects Longtem expr ~ [IJuri ---- Restroom exposes J-- OLra rman General Population - Hazard via dermal route Systemic effects Looptem exposre Norn ssssimrt obs id rr ~ J ------ Local effects Longerm exposure oo ~ resashorttomexposre orsdssssiment oaddts General Popula-tHaizoarnd via oral route Systemic effects Longton exposes Autrtsomhexrpotse Madson novwdicnciod `General Population - Hazardfothe eyes Local efects [rT ---- Additional information - General Populstior pIoermtmaaan imonneRsTdhrescSpohecneotstofcoe8neess faaomngcroramoiprnaccwoseshnopwittch 6oeuen9w7e2a00st4oeve3 LECH TSoSEAccCoiHRonior)hcTtrhoSamiraogtn nof osto bemviinenmnaybresidc APY ry ct ry copy poco. Uf eImoas tiroo.ct pronfm una) fb rect fon i te