Document zoJ6084Vmke6kN920opBnjj6z

May 10, ISkO Dr, E, C. Dodds Courtauld Institute of Biochemistry The Middlesex Hospital Medical School London, ft. 1 England Dear Doctor Dodds: Please accept ny thanks for the report of your work made to me through Mr. Bovan recently. I am glad to know that things have been moving along, that the methods which Smith took back with him have worked out satisfactorily, and that some solution of the analytical problem In connection with the manufacturing plant seems to be in the of ring. r Ther Is one phase of the experimental work which is of considerable interest to me, and I should like to have anything In the way of dotal ed reports which will enable me to understand It3 significance, and to compare your observations with our own. I refer here to yur observations on the relation ships between lead metabolism and that of calcium and phosphorus. For several years we have been studying the lead metabolism of human subjects with known experi mental additions of lead to their oral Intake. I am studying the r suits of these observations In a detailed fashion and I am very anxious to know what are the effects, If any, of variations in the calcium and phosphorus content of the diet over either short or long periods of time. Your data would be of considerable use to me In this connection and I should be very grateful If you could find the tine to report to me in some detail on just what you have done and what results have been obtained. In thie connection I think It would be useful if results were reported to me from your laboratory at more or less regular intervals on the lead work. Obviously I shall make no use of the data my3 If except for $y own Information, since It i3 the essence of our arrangement that you ar > responsible for your own work and for Its publication. On the other hand it was also cur understanding that I could be of considerable use to you la the direction of some of your activities^ or at least in orienting certain phase:; of them so as not to waste time unduly. I should better be able to do this if I knew precisely what is 1 - 2- In large measure this same suggestion is pertinent in connection with any work which you may do in connection with the manufacturing activities. We have a large mass of data and our experience should be of the greatest usefulness in the interpretation of the results obtained on these workmen. I should be very glad, of course, to send you our reports on various phases of this problem, but I believe it would be of the greatest practical usefulness both to your laboratory and to the manufacturing enterprises if we were to review your results, comment upon them and make suggestions for the continuation of these observations. On Bevan's recent trip, we talked over this matter and we came to the conclusion that it would be highly desirable and mutually profitable if we wore to coordinate our activities in such a way that I could profit by your observations and you could profit by ours. I am quite in agreement with Sevan that this should be done and I feel somewhat negligent in not having been more active in the past year in maintaining contact with your work, I have been deeply engrossed in our work here which has been quite heavy, Indeed, I believe, somewhat too heavy. As a consequence I have had very little time for anything else. Undoubtedly the continuance of the war will exercise a very important deterrent influence upon our present relationships* Nevertheless I believe that we should maintain them as well as possible and be prepared to carry on in a concerted fashion when something approximating normal life returns again to your part of the country I can not convey to you my un happiness over the outbreak and the continuance of this war, and, therefore, I shall not try to do so. I do, however, wish to convey to you my very best wishes, my hope that you will not bo too badly disturbed and that we in common with other civilized people may soon be able to return to undisturbed and comfortable relationships. Sincerely yours, HAKsi s Robert A. Kehoe, M D.