Document zdojJg6daLJvaezrBDzbjmOja

* Or. R. I. Kelly MAXM OfFICR - 2 A prll 10, 1956 HTDRAULZC yiflXD D13003101 WITH CAPTAIN 3T0HK - P. 3. MAYT The Navy la currently interested In only two of our hydnulle fluid*. These arei- 1) Pydraul 150 This fluid 1* currently being used in ana submarine. In August of lest year we provided the Bureau of Medicine with stat--snta on our toxicity work and our opinions aa to any possible hazards in the use or this fluid. Tha sane Infernation had been furnished the Bureau of Ships several souths earlier. At tha tins the data was sent to Sr. Wbaam, It ana sent to Or. Hodge: and was followed up by a letter (Teat Or. Troon that our opinions and conclusions were sowd. Tbs oaapoaltlon (confidential) of 150 la 70-141. 23-442, and 7-V.X.X. In Movonber of last year we were Informed that a aaaple of this fluid had bean sent to Or. Lehaan tor investigation, allegedly ollalcal. Vc have been unable to loam what work Letpan did and what results ha obtained, Pteewnbly tha Mtvy daaidad to test use this fluid in spite of laak of approval by tha Bureau of Medicine. To data as have not heard of any difficulties encountered la sutanarlns uae. Tbs attached correspondence does relate a ease of skin lrrltatlon allegedly due to this fluid la a dock-aide rartr-uy of tha system in which the fluid was to bo used. The case of skin Irritation any have been due to other factors such aa poison Ivy. The Navy and the Pnrtansiith Navy Xhrd agreed that this night be the case. Also during tha nark-up trlala an englhaar had a stream of the fluid under pressure sprayed Into his month whan a Una rupturad. Kxeopt for a sore throat for perhaps up to two weeks, there were no other reported eysgsono. X plan to discuss sure fully (yet within the Units of tha confidential nature of the subject) the sogoalticn of 150 with' Harold Hodga and Norton Nelson at the tint of the Philadelphia nesting. X do not believe febat any of the Navy people nor their consultants have been told that 150 contains no TCP. Litzsinger has told aw that we certainly tan nghaal sc fELa point. MONS 095628 Sr. X. I. tally -2- April 10, 1956 2) 08-70 (fluid TAT) This la tha fluid currently of interact for uao aboard airoraft oarrlara and la alallar to tba Celaaeae product, Calluluba 220. We do not know tha oaapoeltlon of our pfaraphate aatara aada from tba oraaola and xplanola In tba raw material. We do know that tba paroantaaa of TOCF in tba 08 70 will ba canaldarebly laaa than In our plaatlalaar-grada TCP. Further, tba amounts of nota and para oraaol pboapbata ahould ba ooneldembly laaa alnea tba raw notarial oontalna only 30 pareant oraaola to basin with (thla figure la euarratlp to ba aonaidarad confidential). Tba other 70 paranat of tba raw notarial la anda up of xplanola and ahould prmtna a tri aryl pboapbata high In tba many poaalbla lacanro of tba eocollad TAP or triacyl phoaphata. Thara la attaabad a coup of tba aauta tonicity data on 08-70. Thla la to ba repeated and extended In tba work currently vmderray at Kettering. Our projeet tbara lncludaa tba followlngi a. Dataralna tba MU) or Ukn (thldbarar you think appropriate) in ana deader atenaab tuba to rabblta, rata, chlckana, and oats. b. Ootaralna tba nlnlnun lethal Inaaaa tban ralntalnad upon tba lntaet and unaTradad akin of iraobUlead rabblta In rubber cuffa far twanti'four hours. c. Dataralna tba aauta tanlelty of the mat tban inhaled by croupe of antrala for porloda rudm frra one to aevan boura. d. Cboltnaataraaa inhibition raasuroranta on rabblta follow!n rapratad akin applloatloai and paaalbly foilowln repeated aspoeuree to mat. A haven't nado definite ooraltranta to Treon aa te ben arah Tba Cary and tbelr aonaultanta have aakad ua fbr a atatarant on our rannfaaturlas aaparlanca w&tb thla fluid. Clara ra bate not even produced pilot plant guautltlea of tbla Material, wo obvlaualy have no plant aaparlanca to report, fib tba otbor band, m bare 20-30 peers experience in tba product ten and handling of a trlcreapl pboapbata aontatnine rare trlortbeorsspl phoaphata then will bo praaant la 08-70. Ac pan knew, this experience baa boon ocapletalp without anp icitnrard Incidents. All of tba aauta toxicity data on tba xplanol phoaphatra Indi cate a lower order of tonicity than with tba oraapl laraara. It la true that m do not know whether tbara la a wide rarlatlra la tba tonlaltp of tha different xplanol laorara (aa thara la In tha TCP laorara) but tbla doee not appear to bo toe 1pertant In view of tha Indicated low order of tonlaltp of tha MONS 095629 Dr. R. E. Kelly -3- April 10, 1956 xylenol phosphates as a group. We should have available soon after the first of June Troon's report on our fluid. These we will be happy to send to Dr. Shone as soon as available. The only other point I think you will want to consider specifically with him Is the value of a letter from us discussing our experience with TCP sued trying to relate this to possible experience with TAP. EPWiaw Attachments Elmer P. Wheeler , MONS 095630