Document zdNeMYqNBdMdZDZ6730NaaaOm

STUDY PLAN (Revised April 22,1997) COMBINED INHALATION TWO-GENERATION REPRODUCTION AND DEVELOPMENTAL TOXICITY TESTING OF VINYL CHLORIDE I. Test Requirements Contained in Study Plan Inhalation Two-Generation Reproduction Study of Vinyl Chloride in Rats Inhalation Developmental Toxicity Study of Vinyl Chloride in CD Rats II. Administrative Official and Project Manager: Wendy K. Sherman Manager, Vinyl Chloride Panel Chemical Manufacturers Association 1300 Wilson Boulevard Arlington, VA 22209 Phone: 703/741-5639 Fax: 703/741-6091 III. Testing Facility: Huntingdon Life Sciences, Inc. P.O. Box 2360 Mettlers Road East Millstone, NJ 08875 Study Director: Raymond E. Schroeder M.S. Phone: 908/873-2550 (ext. 2910) IV. Professional Qualifications Curriculum Vitae (C.V.) providing the training and experience of each professional involved in this study were provided as an attachment to the original study plan. Copies of those C.V.s are available upon request from Ms. Sherman. V. Identity of Test Substance An analysis of the material which is being used in the studies was conducted and the results are available from Huntingdon Life Sciences, Inc. BFG 00448 VI. Study Protocol The protocol for the combined inhalation two-generation reproduction and developmental toxicity testing was included as an attachment to the original study plan. A copy of the protocol is available upon request from Ms. Sherman. VII. Test Schedule Developmental Toxicity Study: In-life phase starts: In-life phase completed: Progress report: Progress report Final report: October, 1996 April, 1997 April, 1997 October 1997 December, 1997 Reproduction Study: In-life phase starts: In-life phase completed: Progress report: Progress report: Progress report: Final report: October, 1996 September, 1997 April, 1997 October, 1997 April, 1998 July, 1998 BFG 004-J9