Document zdNdp3Qy51qj0DZO69O017RK7

890 7iortbf lindtargh Blvd. ) St. Unis 66, Miisoi CHEMICAL SPECIALTIES DATA REPORT The information In thin rcj>ort was compiled to ansist you in to guide your development work, but Monsanto cannot take your evaluation and development of aperial unca for Monsanto part in the apocific formulation or evaluation of any finished product*. Every effort haw been marie to include pertinent product... since knowledge of such should be reserved to material birring on the subject. Thin information in intended yourself snd is often your most valuable trade secret. . fJOTfL. . ,,(J S . . -n--&---fr /rftn No. .' Ufc+t- piCotvUb cfl -fa*- Date March, 1961U,,<u.t J, fa ^f , ^dk'Udc -7&o Stuyj&i A. . MONSANTO AROCLOR* RESINS FOR INSECTICIDE FORMULATION A Discovery A simple method of Increasing the service life of expensive lindane sprays was developed several years ago by U. S. Depart ment of Agriculture scientists at their Beltsvllle, Maryland, testing Btation. The technique was to incorporate Monsanto's "Aroclor" 5*160, a resinous chlorinated terphenyl in the lindane solution. This pale yellow solid reduces volatility of thelindane -- slows it down to an effective, but not wasteful, evaporation rate. The result is an Insecticide deposit on treated surfaces that lasts up to ten times longer than that left by straight lindane solutions. Normally, simple solutions of lindane leave a crystalline residue that dissipates within a few weeks. On hard surfaces such as glass, metal or painted areas, the residues last only about a week. Because lindane Is a well established and effec tive pesticide, U.S.D.A. researchers sought a way to improve the lasting qualities of lindane residues. Of numerous com pounds tested, "Aroclor" 5**60 gave the best results at lowest cost. Test Work A major objective of these studies was to develop a suitable formulation for application to crops and other plants. Al though results under carefully controlled conditions were quite promising, subsequent tests by other agricultural ex perimenters gave only moderate success. Consequently, interest has been slow to develop In agricultural circles. Apparently, the vagaries of sunlight, weather, and plant growth represent too many variables for effective study of the formu lation residues by direct application to exposed plants. Aroclor: Reg. U. S. Pat. off. ?485 The informelton In thU bulletin b, to our beM knowledge, true end aocurele. but all recommendation* or au*|w.tlena ere made without Suerentee, since tbe condition* of xm ere beyond our control. The furwento Chemical OjMtywy dieoUlitp any liability Incurred In Connection with the ue of the1* date or euggeellohe. Furthermore, nothing contained herein ahall be oonatrued m e reoom mondetlon to uae any product in conflict with exletlng patent* covering #ny tnaterlal or IU uh. ad ta I TOWOLDMONOQ43558 o () A Mew Idea But another possibility for putting the U.S.D.A. discovery to work has lain dormant until recently^ thin la the bosslbllity of using to good advantage the ability of "Aroclor" reelns to make the lindane adhere to smooth hard surfaces like metal, glass, painted areas, eto. This would oonslst of painting or spraying "Aroclor"/llndane formulations on Buoh areas as the Inside of garbage can lids, on window screens, doorsllls, the painted walls of outbuildings, dairy plants, storage areas, eto.. In order to obtain lasting control of files, ants, roaohes, ellverflsh and other troublesome pests. Suitable formulations oan be readily paokaged In shoe-polish type "dauber" bottleB, aeroBol spray canB, and bulk packages for meohanlcal spray application. Development of this Idea 1b based on the following! Advantages of Using "Aroolor" Resina In Insecticide Formulations * A suitable "Aroclor" (Monsanto makes Beven) can remarkably extehd the effective life of lindane and other chlorinated lhseotloldeB as much as ten times (up to 2 and 3 months). * "Aroclor" resins are very low In cost (around 20^/lb.). * Small quantities are sufficient (5 to 25 parts per hundred, by weight). * Formulation Is extremely simple -- the resin Is dissolved In a suitable solvent compatible with the Insecticide. * Stable In Inventory and In Insecticide formulation. "Aroolor" roBlns are fire-resistant, non-oxldisable, non-corrosive, withstand weather extremely well. ' Non-stalnlng "Aroolor"/lnsectlclde films formed when the solutions dry are prac.tloally Invisible. "Aroolor" 5460 hasa pale yellow color as supplied. Other suitable "Aroolor" products are nearly oolorlesu. , * "Aroclor" reslnB are odorless -- won't Impart "ohemloal" odors. * "Aroclor" reslnB are safe to handle as long as they are not volatilised and Inhaled. They are praotloally non-volatile at ordinary temperatures, do not Irritate or sensitize normal skin. * The nature of the residue can be varied. Monsanto supplies a variety of "Aroolor" roBlns. These are ohlorlnatod to various degrees and vary in physloal properties as follows* Monsanto Chemical Specialties Data Report CS-6, ....Page 2 0217486 TOWOLDMONOQ43559 O0 Chlorinated Terphenyls Aroolor 5460 - Yellow, transparent, friable solid (dries hard) Aroolor 5442 - Yellow, transparent, sticky semi-solid (dries tacky; Aroolor 4465 - Yellow, transparent, brittle resin (dries sticky) Chlorinated BiphenylB Aroclor 1262 - Light yellow, sticky, viscous semi-solid (dries stic Aroolor 1260 - Pale yellow, soft, sticky semi-solid (dries sticky) Aroclor 1254 - Pale yellow, vIscoub oil (dries "wet") Experimental Work and Formulations The following information was derived from preliminary reports on work done by U.S.D.A. research groups. These data are not to be construed as recommendations by either the U.S.D.A. or Monsanto, but rather are Intended to serve as a guide or starting point for the development of private formulations. Fifty to 200 milligrams of lindane per square foot of surface has given good Insect control on nonporous surfaces. The ratio of lindane to "Aroclor" 5460 has been varied from 1:1 to 1:4. For moBt purposes a lsl or a 1:2 mixture Is satisfactory. Formulations as used In the U.S.D.A. experiments ares 1) For application as a solution. Lindane "Aroclor" 5460 Carbon Tetrachloride 5 parts by weight 5 parts by weight 750 ports by weight (Carbon tetrachloride 1b toxic and should be handled with extreme caution. Less toxic solvents are easily obtained.) 2) For application as an emulBlon. , Lindane "Aroclor" 5460 Xylene "Triton" X-100 (available from Rohm & Haas) 20 parts by weight 20 parts by weight 100 parts by weight 3 parts by weight To obtain a stable 156 lindane emulsion, mix 1 part by weight of the above concentrate to 13 partB by weight of water. Monsanto Chemical Specialties Data Report CS-6, ..........Page 3 0217487 TOWOLDMONOQ43560 o) 3) For une at) a pressurized (aerosol type) spray. a) Lindane "Aroolor" 5460 Methylene chloride "FreOn" 12 (DuPont) 5 parts by weight 5 parts by weight 40 parte by weight 50 parts by weight b) Lindane "Aroclor" 5460 . Cyclohexanone Ortho-dichlorobenzene "Freon" 12 (DuPortt) 6 parte by weight 5 parts by weight 10 parts by weight n parts by weight partB by weight Experimental Results - American RoacheB Using Formula 3 or 3b, the toxloant was applied onto a painted wall, depositing about 200 mg./sq. ft. of lindane and a like amount of "Aroclor" 5^*60. When the toxicant coat was one month old, it gave 90-100# kill of Amerloan roaches when the roacher oontalned in a petri dish were placed against the surface of the treated Wall for two hourB. The U.S.D.A. research team found that the lindane-"Aroclor" 5460 mixture (used at the rate of 50 mg* of actual lindane per sq. ft.) would kill 80# of all oookroaches exposed for 2 hours to a 60-dayold treated surface. It remained lethal to 66# of the roaoheB after 90 days. Regular lindane sprays used at the same rate killed only 4# of the roaches after 60 days. Results with Houseflies Deposits of 25 mg. of lindane plus 25 mg. of "Aroclor" ^H60 applied from carbon tetrachloride onto glass and aluminum (hard surfaces) gave 100# kill of normal houseflies exposed for 2 hours to these treated surfaces after they had aged 18 weeks, the duration of the test. Without the "Aroolor" the hard surfaces treated with lindane alone were effective only about a week. A lindane plus "Aroclor" mixture sprayed as an aerosol onto leaveB of a willow tree continued to kill houseflleB after 2 months of outdoor weathering. Careful Inspection of the treated leaves showed that the toxloant was held firmly to the surface and notwithstanding rain and weather, the costing re mained in good condition. Also, within 11mltB of a preliminary Inspection there seemed to be no Injury to the willow leaves. Monsanto Chemical Specialties Data Report CS-6, ..........Page 4 0217488 TOWOLDMONOQ43561 oo (Notei The primary purpose of thin report 1b to provide In formation for the development of suitable 'Insecticide formulatlono for application to "nonnonsitlve" surfacoB such bb metals, glass, paints, and other materials that will not be damaged by the application. Development of formulations for living plants requires sufficient test work to Insure that the formulations will not be injurious to the plants or their products.) Another Formulation Reported A more recent development In these experiments Is the following Bimple formulations "Aroclor" 5460 25# Lindane 25# Methylethyl Ketone (MEK) 50# Work on this was reported In the August 14, 1954 Issue of Chemical Week magazine. ThlB simple formulation appears to be most suitable for "painted on" formulations packaged In bottles but should be used with caution In mechanical spray equipment since the MEK solvent will soften rubber and certain plastics. The formulation could also be modified easily for aerosol packaging. Since MEK evaporates rapidly, It should'not>seriously affect painted areas unless too heavy applications are made. The package label Bhould inolude a caution to this effect. Also, MEK Is flammable. Possible substitutes that are less flammable are methylchloroform or a mixture of methylchloroform and methylene chloride. Formulating Other Insecticides The beneficial effects of "Aroclor" 5460 apply generally to other chlorinated Insecticides including chlordane, aldrln and dieldrln, but do not apply to phosphate typo insecticides such as TEPP, parathlon, methylparathlon, malalhlon and chlorothlon. ' . # # * For Bamples of the "Aroclor" products mentioned In this report, contact the nearest branch office (Bee attached list) or write tot MONSANTO CHEMICAL COMPANY Organic Chemicals Division Plasticizers Department : 800 North Lindbergh Boulevard St. Louis 66, Missouri Monsanto Chemical Specialties Data Report CS-6, ....Page 5 0217*89 TOWOLDMONOQ43562 MONSANTO CHEMICAL COMPANY Organic Chemicals Division District Sales OfflceB ATLANTA: 1401 Peachtree St. N.E., Atlanta 5, Oeorgla BOSTON: Everett Station, Boston 49, Massachusetts CHICAGO: McOraw-Hill Building, 520 N. Michigan Ave., Chloago 31, 111. CINCINNATI: 8330 Victory Parkway, Cincinnati 6, Ohio CLEVELAND: 427 Hanna Building, Cleveland 15, Ohio DETROIT: 18230 Grand River Avenue, Detroit 23, Miohlgan HOUSTON: 2472 BolBover St., P. 0. Box 6863, Houston, Texas LOS ANGELES: 6670 E. Flotilla St., Lob AngeleB 22, California MINNEAPOLIS: Foshay Tower, Room 515* Minneapolis 2, Minnesota NEW YORK: 445 Park Avenue, New York 22, New York PITTSBURGH: 20 Cedar Boulevard, Pittsburgh 28, Pennsylvania SAN FRANCISCO: 111 Sutter Street, San Franolsoo 4, California SEATTLE: 911 Western Avenue, Seattle 4, Washington SYRACUSE: 731 JameB Street, Syracuse 3, New York WILMINGTON: 2005 Conoord Pike, Fairfax, Wilmington 3, Delaware *#### LONDON: Monsanto House, 10-18 Victoria St., London S.W. 1, England MELBOURNE: 256 Flinders Street, Adelaide, Australia MONTREAL: P. 0. Box 900, Montreal 3, Canada TORONTO 183 Front St. East, Toronto 2, Ont., Canada VANCOUVER: 1550 Rand Avenue, Vancouver 14, B. C., Canada qO 0 TOWOLDMONOQ43563