Document zd6rkNmYb9nMMav33MwYRgxgB

Industrial Hygiene Digest February, 1956 243 Cyanosis and Dyspnea in SUtcoete. F. Tronchettl tsd A. Toreoli. Phii mcd. 63. 1390-1392 (Oct. IS, 1955). French. Snatnation of 160 patient* with silicosis *bowed that those who had dyspnea on exertion also had evident, constant signs of bronchitis. In some cases the Illness Is uaai - fasted by this bronchitis alone; bronchoscopy and bronchography reveal spasm of bronchi and bronchioles. The authors believe that the broncho spaatic tendency Is the moat impor tant feature in the dyspnea of silicosis. Considering cyanosis, it has been shown by angio pneumography that among silicotic patients the exclusion of large capillary beds la very frequent in those with severer cyanosis. The capillary exclusion is accompanied by de- crease in pulmonary circulation time. It seems that the opening of arteriovenous shunts accounts, at least in part, for the cyanosis of silicosis. -- J. Am. Med. Assn. 244 Silicosis and Coronary Sclerosis. F. Boemfce, U. Piroth, andF. J. Schulte-Stracke. Beitr. SUikose-Forsch,- No. 33, 1-29 (1955). German. The relationship between silicosis and its effects on the heart and circulation are discussed. The reports of s large number of autopsies were examined, analyzed, and summarised. It was established that a connection exists between silicosis and coronary sclerosis; this does not suggest, however, that in every case of silicosis the development of coronary sclerosis, or unfavorable influence on existing sclerosis. Is to be expected with certainty. Chronic diseases of the lung, including silicosis. Is one of the exogenous factors In the formation mnd extension of coronary sclerosis, la so Car as they reset on the coronary system through injury to the pulmonary circulation. It was not possible, from the results of the Investigation, to indicate which disease Is the more important cause of death when both are present. -- Cond. from Bull. Kyg. 245 Seme Problems of Pathogenesis of Pneumoconiosis. M. Timor. Gigieaa i Sanit. Mo. 7, 25-33 (l9$SJ. Russian. A brief review is given of existing material on pneumoconiosis caused by dust Inhalation. It is shown that silica determination in blood and urine is not a satisfactory diagnostic tool since patients with advanced stages of the disease do not show super normal silica levels. Oast (cement, quartz, silicate) introduced into animals via the lungs or digestive tract results la Increased silica levels in the bodF Quids usually not less than 1 -2 days after the administration of the soluble varieties (cement), while the less soluble varieties produce sa irregular pattern which Is not significantly different from control variations. -- Chem. Absts. 24b Investigations into the Size of Dust Particles Deposited in Different Parts of the Lcngs when breathing Dusty Air. A. Policard and A. Collet. - Arch, maladies profess. 16, 239-242 (1955). French. Most of the information on the distribution of Inhaled dust particles depend* upon observations made on pneumoconiotlc lungs. Tha investigation described Is baaed on obser vations on eight miners who died suddenly at work and were not pneumoconiotlc. Only coal particles could be noted with certainty. Most of the particles found in the bronchi, bron chioles, alveoli, and pleurae were smaller thau 2.8 microns. Similar small particles were found in tho cervical glands. The observations seemed to indicsto that 95f< of the particles in the alveoli are loss than 2 microns; particles of 2 to 4 microns form about 5%. The rest are negligible. These results confirm for healthy lungs the estimates made from pneumo- coniotic lungs. Nevertheless, particles as Urge ae 10 microns are found in diseased lungs; how they get there Is s mystery. -- Good, from Bull. Hyg. 247 The Pathophysiology ef Respiration in Silicosis and the Assessment of Capacity for Work. t1. H. Rossier, A. Buhlmann,' and P. Luchslnger. Deut. med. Wochschr. 80, 608-614 (Apr. 22, 1955). German. Disturbances of lung function in the early etages of silicosis are mostly concerned with ventiUtion, and in progressive stages these disturbances^^re-.proved to be due to reduction 21. 11 206 1380