Document zbvOr4J3Rbz7mVrDKMjg2ZDym

D r. K. D. B ryson 10515 C arn eg ie .avenue C le v e la n d , Olilo Dear D octor Bryson: I am s e n d in g h e r e w ^ l ^ ^ o o p y ^ f o u r a n a ly tic a l r e s u lts on th e tis s u e s o f m P B I ^ which you made p o s s ib le f o r us t o o b ta in , to g e th e r w ith o u r r e p o r t . on th e sam ples of u rin e and b lo o d . The fin d in g s on th e n e cro p sy a re v ery h ig h b e in g w e ll above n o rm al l i m i t s and i n l i n e v /ith th o s e we have e n c o u n te re d i n s i m i l a r c a s e s . One e x c e p tio n i s th e bone which is w ith in norm al l i m i t s . The fin d in g o f a low c o n te n t of lead in bone in re la tio n to th e high concentration in the o th e r tis s u e s is d e fin ite evidence of a re c e n t exposure of c o n sid e ra b le m agnitude, a l l of which i s c o n s is te n t w ith our diagnosis in th is ease. In so f a r as the blood sam ples a re con cerned, both re s u lts are s lig h tly above norm al, but as the lim its o f norm al v a ria tio n of co n cen tratio n of lead in blood have n o t y e t b een e x a c tly d e f in e d , we c a n n o t a t t a c h d e f i n i t e c lin ic a l sig n ifican ce to these re s u lts . The u r in a r y f in d in g s a re e s p e c ia lly in te re s tin g . A ll four r e s u lts a re above norm al and you w ill n o te th a t in each case U rine #1 i s low er th an U rine #2. U rine $1 was tak en in th e l a t e m orning a f t e r c o n sid e ra b le w ater had been in g este d , w hile U rine #2 .represented th e specim en passed on a ris in g and probably in clu d es a g re a t p ro p o rtio n of th e n o c tu rn a l o u tp u t. The la rg e 24-hour specim ens w hich I o b tain ed have n o t y e t been an aly sed , b ut th e c o n c e n tra tio n s in th o se sam ples sh o u ld re p re s e n t th e mean o f th e le v e l o f e x c re tio n o v er th e 2 4 -hour p e rio d and amounts sh o u ld l i e somewhere betw een th e fig u re s- g iv en f o r U rine 1 and U rine #2 in each c ase . W ith k i n d e s t r e g a r d s , I am C ordially yours, . WEMivr . W i l l a r d Y ; Metohia", M. >.