Document zbbYnNDBdO8EgeoQJVLm9Mmpn

Applied Health Sciences, Inc. Case-control Study of AML and NHL Additional Budget Estimate for 2007 and 2008 2006/12/8 A 1 Rationale and assum[!tions 2 3 Assuming that the end of case accrual will be extended to December 2007, we will need to extend the timeline of the case-control study to December 2008. 4 We further assume that final diagnoses of all patients and patient interviews will be completed by March 2008 and exposure assessment completed by June 2008. 5 We will then perform the following tasks in July-December 2008: final QA/QC, data editing, statistical analysis, presentations, discussion with SRP and report writing. 6 7 In addition, based on our recent experience, we need to increase our efforts of QA/QC, database testing and auditing, and monitoring of patient interviews in 2007. 8 For 2007, we have also added two additional trips to Shanghai (to the three already approved, with a new total of five trips). 9 10 11 Labor 12 13 Category 14 Chief Epidemiologist (PI) 15 Biostatistician 16 Statistical programmer 17 Research/Administration assistant 18 Consulting industrial hygienist 19 Total labor in 2006 dollars 20 21 Meetings/working tri(1s (time & eX(1enses) 22 23 24 Trips to Shanghai (10 days each) 25 Trips in USA (3 days each) 26 Total for meetings/working trips in 2006 dollars 27 28 Miscellaneous expenses (copying, domestic & international calls, mail) in 2006 dollars 29 30 Total additional budget in 2006 dollars (labor, trips & miscellaneous expenses) 31 32 33 Yearl~ budget estimates with a 5% annual adjustment 34 35 Total additional budget by year (with 5% annual adjustment) 36 37 Budget already approved (Contract No. 2004-101153, Amendment No.1) 38 39 TOTAL REVISED BUDGET BCD Hourly rate in 2006 $355 $175 $150 $115 $250 Hours 120 80 80 20 0 Year 2007 Amount $42,600 $14,000 $12,000 $2,300 $0 $70,900 Unit cost in 2006 $39,000 $11,600 Year 2007 No. Amount 2 $78,000 0 $0 $78,000 $1,000 $149,900 Year 2007 $157,395 $456,475 $613,870 SH ELL-MCCLU RG-053563 Applied Health Sciences, Inc. Case-control Study of AML and NHL Additional Budget Estimate for 2007 and 2008 E FG H 1 2 3 4 5 6 7 8 9 10 11 12 Year 2008 Total 13 Hours Amount Hours Amount 14 540 $191,700 660 $234,300 15 400 $70,000 480 $84,000 16 400 $60,000 480 $72,000 17 160 $18,400 180 $20,700 18 80 $20,000 80 $20,000 19 $360,100 $431,000 20 21 22 Year 2008 Total 23 No. Amount No. Amount 24 5 $195,000 7 $273,000 25 2 $23,200 2 $23,200 26 $218,200 $296,200 27 28 $3,000 $4,000 29 30 $581,300 $731,200 31 32 33 Year 2008 Total 34 35 $640,883 $798,278 36 37 $0 $456,475 38 39 $640,883 $1,254,753 2006/12/8 SH ELL-MCCLU RG-053564