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AR226-2758 FOR DU POUT USE ONLY Copies co E. 1, du Font de Nemours and Company llaBkeii Laboratory for Toxicology and Industrial Medicine Elkton Road, Newark, Delaware 19711 HASKELL LABORATORY REPO&T NO. iUUb-BU 1 Teote -nw Haak-'ll No. ''cher Codes Study Initiated/Completed ----So/U/SO - io/i6/6fi Material. Lttedby Polyiaer Products Dept. Washington Works SKIN IRRITA^IOM TE9T ON RABBITS Procedure; Six male albino rebbits were clipped free of hair on the trunk and lateral area and placed in PDA-type stocks. Doses of 0.5 ml of undiluted test material were applied to infcaet skin under 1 1/2" x 1 1/2" 12-ply gauze squares. Rubber sheeting was then loosely wrapped around the trunk and secured with adhesive cape- After 24 hours, the rabbits were rsaoved from the stocks, the patches cakea off and the reactions observed. Observations were also made at 4o hours' Segutts; ^4-Hour Observation___ Erythema Bdeaa None 6/6 None 6/6 4y-Hour Observation Erythema Edema None 6/6 None 6/6 Summary: shaved intact expected from employed. caused no skin irritation in 24 or W hrs when cesced on Bkin of 6 male rabbits. No unusual dermatitis hazard is handling this material if good industrial hygiene pract the are 1 - Company Sanitized. Does not cona TSCA CB \/^^/ t^^^ --*John Report by: t- E. Henry (1 Technician Approvet' by; Q^^-JU t V!^^--^ Gerald L. Kenned/ Chief, Acute Investigations Sectic: JEH:jrg Study Director: 0. L. DashieU Date 3-seuadi Decssber 9, 1980 'Kepoct No. lUUo-aU - Z - --------,S^0.------co^TSCACB,