Document zbGyGJX2abxV7D3rkDp3w072B

J, ' ' | ' t^HtSI I H November 20, 1936 LeRoy U. Gardner, U. D., Director, The 6aranGC Laboratory, ' Barannc lake, New York. . Doar Dr. Gardner* At a meeting yesterday attended by certain brane lining manufacturers, Ur. Simpson and I were able to preoent to a fairly large group of interested corporations the proposal that one of your duntlng chambers be engaged for further experi mentation with asbestos dust. '' The proposal was very well received and it appears that not less than eight, and ptrhpa ten or more, corporations will participate In financing these further experiments along the lines diacussed when we met with Dr. Lanxa and Dr. HcConnell a fc-w days ago. Accordingly, you may consider tills letter as an authorisation to you to commence the contemplated experiments with asbestos dust for the purpose of determining more definitely the causes and effects of nsbestusis. It is my understanding that, among other questions which It is anticipated theso experi ments will answer, are the following! (1) Yhat concentration of dust Is necessary to ;rouuce the fibrosis of the lungs which Is designated as . asbestosls. (2) Whether exposure to asbestos du3t will produce . asbestosls without the oxistence of previous infection and whether the X-ray changes found in advancod huoan asbestosls can be reproduced in animals without Infection. (3). Whether tho fibrosis produced by asbestos is of the progressive typo, that is, will the fibrosis Increase (once it has started) after exposure to the dust has ceased, plaintiffs Exhibit . filllllllllllllllllillilllllll ~ S-BW-2 (4) fVhetbor the fibrosis resulting from exposure to asbestos dpst Is occasioned by the silicon con tent of the asbestos or by its fibrous structure. (5) Whother the presonco of"asbestos bodlos" has anydiagnostic significance, It is also our understanding that these experiments *111 require approximately three years, which will mean that they will not be'concluded until about the end of the year 1939; and that they will cost $5>000 annually,' or e total of $15,000. * . ' It_ia our further understanding that the results obtained will be considered the property of those who are advanc ing the required funds,, who will.determine whether, to what extent and in what mnnntr they shall-be made public. In the event It is deemed desirable that the results be made public, the manuscript of your study will be submitted .to us for approval prior to publica tion, . ' ' I shall appreciate your advising me if the foregoing . accurately expresses the proposition you had in mind. Alno, let mo know the manner in which you would like to have- the funds ad vanced to you. Would you, for example, desire to have $1^50 paid quarterly In advanco, or Just what arrangement would suit you best? Any method you suggest will be satisfactory. S.ince the experiments are being underwritten by a rela tively large group, it has been suggested that, as a natter of con venience, any communications regarding the work he addressed to me end I will, where necessary, communicate the contents thereof to Mr. Simpson and the other parties. You will be provided with funds by either Jolms-Manville Corporation or Raybestos-Manhattan, Incor porated and we or they will secure from the other parties their ^ro rata contribution. . I will advise you later of the names of the other con tributing parties. ' ' . I shall appreciate your informing me at the earliest possible moment whether the arrangement as outlined herein meets with your approval. Slncurely yours, tLJm / Vandiver brown Y3:T Goner&l Attorney rtf