Document zQobNp2qz908N3Xdjm2Qgaggg

FILE NAME: Chemical Abstracts (CHAB) DATE: 1953 DOC#: CHAB035 OCUMENT DESCRIPTION: Abstract Originally Published in 1953 by Boemke "7 'li 'O ld - 4471 Chemical Abstracts 4472 Yul. 47 rcabsorption which arc inrlcpcnrlciit of filtered N'u load. while the water content was normal. Following therapy 35 references. Theresa McKee with insulin and 0.85% XaCl sola, the patients showed Study of mast-cells in human subjects with relation to rapid clinical improvement and return of the plasma pH, bi atheroma, heparin and cholesterol. I). P. Hasti. Indian carbonate and water to normal. Undesirable side effects Heart J. 4, (15 -71( 1952).--Mast cells occur in the human were occasional hypernatremia, const, transient hyper yl ' aorta, coronary artery, and lungs. Fewer occur in athero- chloremia, and hypokalemia, which persisted several days. lnatus vessels and under these conditions rupture of the cells Y ith treatment the erythrocytes lost no further K, but did occurs. Few mast cells occur in the lung when there is lose water and Na. Xu rcaccunitilatcd in the cells more I: pulmonary hypertension and the pulmonary artery has rapidly than did K or water. In m o s t patients, both cell undergone atheromatous changes. A large no. of mast cells -water and K were lower than normal at the time of dis occur in lung tissue when there is pulmonary tuberculosis charge from the hospital. There is a parallelism between \ with no atheromatous changes in the pulmonary artery. water and base shifts in the crythroevles and in the total cell These findings suggest a close connection between mast mass during recovery from diabetic acidosis. 28 references. cells, atheromatous changes, and cholesterol. It is sug John T. Myers sL gested that the stress on arterial walls, which is caused by generalized or pulmonary hypertension, damages the mast The cholate:cholesterol relationship in clinical and ex perimental nephrosis. Ray H. Roscnman, Mever Fried cells with a subsequent reduction in heparin production; man, and Sanford O. Bvcrs (Mt. Zion Hosp., .Sail Fran the power to rupture the globulin lipide bond then de cisco, Calif.). J. Clin. Invest. 32, 121-4(195.3).--An excess creases. This agrees with the view that an increase in the -accumulation of bile acid (hypcrcholatetnia) was found in no. of mast cells produces extra heparin and thus produces the blood of human subjects with nephrosis and in the blood a lowered plasma cholesterol concn. Theresa McKee of rats in which exptl. nephrosis had been induced by injec Lung carcinoma caused by asbestos inhalation. Fr. tion of antirat-kidnev serum when hypercholesterolemia Iloetnke (Stfidt. Krankenanstalten, Dortmund, Ger.). was also present. The nephrotic rat also showed a dimin Med. Monatsschr. 7, 77-81(1953).--The relation between ished ability to rid his blood of excess injected cholate. librotic changes caused by asbestos deposits in the lung and Feeding of cholate to nephrotic rats appeared to prevent the carcinoma is discussed. The lower lobe is the site of pre decrease of plasma cholesterol, which usually occurred dilection. Characteristic are the multicentered develop following the initial rise. John T. Myers ments of flat epithelium carcinoma. A. 1C. Meyer . . Pulmonary hypertension. I. Pulmonary circulatory dy- Determination of 17-ketosteroids in acne rosacea. Ro namics^ in patients with pulmonary emphysema at rest. dolfo .Vestor Corti and Pedro if. Magnin. Semann wed. Paul N. G. Yu, Frank Lovejov, fr., Howard A. [oos (Buenos Aires) 1953, I, 113-15.--The values found were Robert E ; Nye, Jr., William 8. McCann, S. John Ve'rnur- normal in rosacea, higher in common acne, which difference elli, and Carol Gouvernettr (Univ. of Rochester, Rochester is of diagnostic importance. A. E. Meyer X.Y.). J. Clin. Invest. 32, 130-7(1953).--The degree of Altered liver function of chronic congestive heart failure. pulmonary hypertension varied directly with the severity John M. Evans, Hyman J. Zimmerman, J. Grant Wilmer, of emphysema, hypercapnia, and anoxia. The O satn. of Lawrence J. Thomas, and Clayton B. Etheridge (George arterial blood varied inversely with the mean pulmonary * Washington Univ., Washington D.C.). Am. J. Med. 13, artery pressure, but did not parallel the other determinants. 7(14-12(1952).--Impairment of the hepatic excretorv ca The O tension of arterial blood did not varv predictably pacity for Bromsulphalcin was often marked, generally with any of the determinants. The C02 tension of arterial paralleling the severity of heart failure. Flocculation anil blood correlated closely with mean pulmonary urtcrv pres turbidity tests were less frequently abnormal, the latter sure, total pulmonary resistance, and artcrioiar resistance, usually in assocn. with the hyperglobulinemia found in but not with ``pulmonary capillary" pressure. The ratio some of the patients. Serum bilirubin concns. were mod of residual vol. to tot.al capacity varied directly with mean erately increased in about 25% of the patients, particularly pulmonary artery pressure and total pulmonary resistance. in those with higher levels of venous pressure. The serum The role of anoxia in the pathogenesis of pulmonary hyper albumin concn. was less than 3.5 g./l(K) ml. in 35 of 50 pa tension is confirmed. CG2 retention is probably important tients; the serum globulin was 3.59% or above in 15 of 50 ' in raising pulmonary artery pressure and in increasing pul patients. The impaired excretion of Bromsulphalcin showed monary vascular resistance. .33 references. J. T. M. a pos. correlation with the height of the venous pressures; The effect of thyrotropic hormone on the metabolism of no significant correlation was observed with the degree of radioiodine in euthyroid, hyperthyroid and acromegalic in arterial O unsatu. 34 references. Barbara R. Murray dividuals. David V. Becker, J. E. Rail, Wendell Peacock, Autoimmune hemolytic disease and cryoglobulinemia as and Rulon W. Rawson (Kloan-Kcttcring Inst, and Memorial sociated with chronic lymphocytic leukemia. Hemato Center, New York, X.Y.). J. Clin. Invest. 32, 149 (10 logic and metabolic studies. Albert B. Craig, Christine (1953).--The effect of a single intramuscular injection of Waterhouse, and Lawrence Ii. Young (Univ. of Rochester, thyroid-stimulating hormone (TSH ) on the metabolism of a Rochester, N.Y.). Am. J. Med. 13, 793-804(1952).--,- tracer dose of I131was studied in 3 euthyroid, 8 hyperthyroid, Reductions in the no. of circulating lymphocytes, in the size and 3 acromegalic patients. When administered 4-8 days of the peripheral lymph nodes, and in the rate of red cell after the tracer I131, TSH increased the level oLprotein-bound destruction were sustained for 9 months following adminis I131and I'57in the blood and of I131in the urine. Methods are tration. of 1250 mg. adrenocorticotropic hormone (ACTII) presented for the esttt. of the total thyroid hormone dis in lo (lays A 2nd course of ACTII produced a less marked charged from the thyroid after TSH and for calcg. the total but still well-sustained response. The expected loss of X, _1 content of the thyroid. Following a standard dose of P, and K occurred. 32 references. Barbara R. Murray ISH, euthyroid patients appeared to secrete more thyroid Observations upon the absorption of urinary constituents hormone than did hyperthyroid patients. The max. effect after ureterosigmoidostomy. The importance of renal dam- - of TSH appeared in the first 24 hrs. in the hyperthyroid age. C. 1). Creevy and M. P. Reiser (Univ. of Minnesota, patients, ami not until 48 hrs. in euthyroid patients. Three Minneapolis). .S'/., Gynecol. Obstct. 95* 589-945(1952).-- hyperthyroid patients demonstrated an unusual method of Absorption of urinary chlorides through the mucosa of the handling radio-I, which was characterized by a very rapid colon after ureterosigmoidostomy can cause hyperchloremia turnover rate of I by the thyroid with abnormally elevated and acidosis. ' Barbara R. Murray h scrum protein-bound radio-I and urinary radio-I levels. 22 Systemic lupus erythematosus. A review of the litera references. ' John T. Myers ture. ,S. William Ross and Benjamin B. Wells (Univ. of Histamine sensitivity and anaphylaxis in the pertussis- Arkansas, Little Rock). Am. J. Clin. Pathot. 23, 189-4! vaccinated rat. Saul Malkiel and Betty J. Hargis (North (1953).--The review includes changes in the blood chcmis-_ western Univ. Med. School, Chicago). Croc. Soc. lixptt. try and the "L .K ." factor. 193 references. J. T. M. Pint. Med. 81,989-91(1952).--Inoculation of the white rat Electrolyte equilibria in erythrocytes during diabetic with Hemophilus pertussis increased its sensitivity to hista acidosis. George Nichols, Jr., and Nancy Nichols (New mine. Pertussis organism mixed with horse serum markedly England Deaconess llosp., Boston, Mass.). J. Clin. enhanced the ability of the horse serum to later produce Invest. 32, 113-20(1953). --Values for plasm,a and erythro- t anaphylactic sensitivity. Richard F. Riley cyle Na, K, and water during diabetic acidosis are com Electrophoretic studies of the serum of horses infected pared with the values ill 21 normal subjects. During acido with experimental infectious anemia. Jean Hirtz (Inst, sis, plasma base concn. was normal and plasma water de frangois ficvre aphtcure, Lyon, France). Rev. immune!. 16, creased. Erythrocyte Na and K concns. were decreased 397-405(1952).--Electrophoretic studies of -1 horses in-