Document zQX7V497dMYnBJxpN5EKx4VO0

was be a to sis, and -Abbommal 'Neoplasm a; :;,E. . Keal. Lancet 2, ?1211 (I960), '* ' ' ,.' i < ,,,. >! .. : . : In 195J,- an iinprsiiion wai formed;At,the LondonHoapical that womensuffe ring" from ' pulmonary aebeatosiehadoyarianncoplaema more often chan other women.:' On the bade of thi* suspicion and became of.the occurrence of other cases, the hospital record* elnce 1948 were investigated. During that period, 23 women and 19,men were admitted5 with a diagnosis ' of aebeetoei*. Iri thie.serie*. jthere wore: 30 death*i (15'men ahd lS women).f Of the**! 14 die with lung cancer (10 men and!.4women).;vThie hlgh-incidence in then it partly due to selscitlon but this does not,apply;to the women, who weraallnon-amokers. 'Death occurred in one man : with peritoneal cancer. and in 9 women with ovarian or peritoneal cancer. Thl* appeared to bt more than a chance association,,and>*pread,fromundiagnosed lung'cancer seemed unlikely. ?' At.leaet .4 of.the tumor's were ,not ofovarianjorigin.;, Some evidence of: hematogenous spread s'ofasbestos fiber* was adduced and it wai suggested that?a'combinatiomof mechanical'and i ^./ohemieai'factorsmay. determine? the? peritoneum? as< the site' of inflammatory and subsequent neoplastic change. No single satisfactory explanation for these cases could be drawn from s.ssthelavailable .material?though:theyrappea'red'to-form a cllnical entity of statistical'significance t* .> ; s' ..'<! > K ."'ir.. 1 .i ' ' ..Can. Med. Assn. J. Absts. * ' , 'V 1" vs . ovl'i ,< -.ii j'.i.-'W; v*'- - 'i'*' .----v t t < -: ' r * ^ \ t ^ ^^ *p ,, mi'Occupational iMedical; Investigation.in.Ccment1 Works;?;;. Jenny M. Battigi;et al. * ": > r' ... ,*'< Schweiz. med. Wochschr. 90, 70S.709 (June 25, I960).' German. 1 , j (Y. (* '' \ ^ ' `i- , , ' 1 , This is the first systematic investigation In'Switzerland into the possibility of res. u piratory>complaints.ansing.f r.om/the:inhalationiof^cement .dust. .u No-free<:silica is presefit in ' Swiss; cement,.so silicosis is not a ?riak','! ?a ;fact confirmed >by the`radiological examination of .ir'i'some^ofvthe;workers1; In,*11,488 employees at.Jfac tones were'-studled. The absentee: rate ait one of. the factories was,much ihigherthanat`other a; the? percentage of men. complaining <of , ; cough nd of;those; with jputum was- also highor in.thla plant. Th'e/cause;of this might be part. <idue;<to: social-factors, '.epidemics,, etc.;: 'A>.study, of'smoking habits;] showsi that exposure to cem? tv -.dust does not increase coughing in amokers. , It'is suggested! that'thosoiwho. are.resistant to .smoker1 a, cough are also resistant to dusti' Non-smokers show a surprisingly high proportion c:;,::>,wtthAchronic ^cough ,as::compared'with figures::given by another author;? ' Perhaps' a better com. `fV'pansonwould? have'ibeen with a non-occupational group studied by the authors themselves. However,,,,itii, conclude d'that'.thi a show,s that; cement dust,Ismrmating-to*the?;respiratory pas. ;.',:; ::iage s;;!;i Physical signs ifound.did,not lead'to-any.defimte 'conclusion;; -.Vital' capacity was not In ' :1: fluenced by the length of'dust exposure.!; >ln-a few. workers the maximum,expiratory force was vj'V'reduced.vs'Aniattempt was;made-.corelatethe.findings, to'themtensityof exposure?by dividing ' the workers into' 3 groups;,, The .2 groups? most,exposed to dust?5showed:a? tendency, to increase ; pathological signs,''but the. difference' was `not statistically significant; r , Bull. Hyg. . 172!, A,Study of- the; Physiological Effectsof Carbon.Black. ^(3) .`Adsorption and Elution, Potentials;; , '^ Subcutaneous!lnlections;1 C. A.-Nau, J. Neal and V, .A. Stembndge..; i ,.-.Arch;.`Environmental! Health -l]; 5:12-533'''(Dec.M960);i : . ; ^> s" `< ^n j';;;.- Neither ibioodl plasma-nor `gas trio juice .elutes any significant adsorbed component .. when a channel black is suspended in either medium for as long as 7 days. Neither blood, ? ' plasma nor gastric juice elutesvany 'significant adsorbed>component;,when a furnace black is suspended an'either, medium for as:long:.as, 7.!;day*. j Channel'iblackV binds", benapy rene adsorb/.' ; ifir i" a rtifictally,'.1, so firmly -that it cannot be.? re moved ..'.'in toto" bybeniene extraction. No signifl*. ; cant .extraction of either channel or furnace .carbon blackwas accomplished wlth!gastric, Juice - to which' LOft; cooking oil was added when contact w aamaintained for ,7 days. Subcutaneous ot . intrapernoneal injectton'in mice of ichannel or furnace .carbon black leads, to ,no' significant , j > changes: from'the normal;, .Benzene extractives oMurnaee blackswhen injected in oil Into , mieo-lead to tumor formation. . Carbon blacks,, channel or furnace, can absorb and;bind know: - carcinogen* so effectively that no tumors are produced when the adsorbed'material Is injects, i :?,subcutaneously,; Trleaprylin when injected.subcutaneously'ln mice may cause tumor formatic, 4 < ' < Authore'/concluslons, '