Document zQLV48rD26KJZaY00zmk33Mj6

FILE NAME: Chemical Abstracts (CHAB) DATE: 1938 DOC#: CHAB014 DOCUMENT DESCRIPTION: Abstract Originally Published in 1938 by Nordmann 7111 Chemical Abstracts 7112 Vol. 32 Brit. J. Expil. Path. 19, 227-38(1938).--The intraperi. 1 maternal blood serum. In umbilical cord scrum and in toneal inoculation of a saline suspension of leuccmic spleen scrum taken from the infant before suckling, agglutinins or lymph nodes of 2 different transmission lines depressedi were not present nor were they found 3 to 5 days after the anaerobic glucolytic rates, but not the respiratory nor delivery, although in some of these cases undoubtedly aerobic glucolytic rates of uninfiltrated lymphoid tissue. agglutinins had been received with the colostrum. In the The inoculation of similar amts, of normal spleens of 2 blood serum of 4 or 5 pregnant women investigated, speci different strains of mice produced no such effect. No fic active agglutinins were found and with them the um inhibition of anaerobic glucolysis could be demonstrated bilical cord serum and the serum from the infants before when normal and leucemia lymphoid cells were mixed in 2 the first suckling showed almost the same values. The Ringer soln. nor when normal cells were suspended in agglutinin value of the serum of the infants did not rise Ringer soln. that had previously bathed leucemia cells. after several days suckling, despite the presence in the Harriet F. Holmes colostrum that they were getting of large agglutinin quan . The industrial cancer of workers in asbestos. M. tities, and in fact decreased after the third day. These I Nordmann. Z. Krcbsforsch. 47, 288-302(1938).--A agglutinins were always present in stronger concns. in the description is given of 6 cases of asbestosis with carcinoma colostrum than in the blood scrum of the mother. These of the lung, including 2 cases observed by N. In 5 of the observations are in contradiction to those showing that 0 cases the carcinoma was a squamous carcinoma with in horse, goats and swine, the immunity is entirely of hornification and the other case was an adenocarcinoma. 3 colostrum origin. Eleanor M. Humphreys Five of the 6 carcinomas were in the lower lobe. Most Blood-sugar investigation in sound and toxic nurslings. of these cases were younger than the av. case of lung car Klingcnbcrg. Arch. Kinderheilk. 114. 100-2(1938).--The cinoma. Exposure to asbestos began 15-21 years before blood sugar in healthy infants up to the tenth month and lasted 7-21 years with one exception. In the case of varies from 72 to 76 mg. %. In 15 cases of intoxication an elderly women of 71 the exposure to asbestos was only the blood-sugar values range from 123 to 176 mg. %, and 1 year and 7 months, 17 years before, but her lungs showed these high figures were obtained even when successful a very high degree of asbestosis. The asbestosis takes therapy was under way, although the highest figures were the form of a diffuse fibrosis throughout the lung with obtained in those infants in which successful therapeu many needles of asbestos present. What property of 4 tics was not established, indicating that exceptionally high asbestos is responsible for the cancer developing on the blood sugar indicates an unfavorable prognosis. groundwork of asbestosis is not yet known, but there may Eleanor M. Humphreys be in asbestos so-called carcinogenic substances. Obesity in childhood. Richard Priescl and Leopold Harriet F. Holmes Frey. Arch. Kinderheilk., Bciheft 15, 1-44(1938).--A Report on the investigations carried on in the Schnee review of observations in a special clinic for obese children, berg district by authorization of the governmental com indicating that the role of endocrine disturbance is com mission for fighting cancer. A. Brandt. Z. Krebsforsch. monly overestd., and that dietary control is often possible 47, 108-11(1938); following abstr.--Cancer of the lung, 5 in cases attributed to endocrine imbalance. There is a has long been known to be frequent among Schneeberg marked tendency for juvenile diabetics under insulin to miners and this article describes a program of an exhaus become obese after puberty, especially girls. tive study being made to det. under what conditions it Eleanor M. Humphreys occurs. Harriet F. Holmes The variations in the blood phosphorus in children with Experimental studies on the question of the Schneeberg pneumonia and the effect of therapy with large vitamin D cancer of the lung. H. R. Dohnert. Z. Krcbsforsch. 47, doses. N. Dunkelmann. Monalsschr. Kinderheilk. 72, 209-39(1938).--Twenty-eight mice from a stock that 36-1-77(1938).--In all cases of pneumonia the inorg. I* were not known to exhibit much spontaneous carcinoma content of the plasma and erythrocytes exhibited a were kept in a Schneeberg mine and survived 2-370 6 hypophosphatemia before administration of vitamin D. days. Of these, 2 were reserved for radiologic study and During the febrile period the P curve usually is horizontal only examd. macroscopically. Most of the animals died and first begins to rise slowly during the convalescence, from respiratory infections. In 7 animals (25%) tumors but in the patients given large doses of vitamin D there were found, and in 2 of these there were multiple tumors in is constantly a rapid rise so that by the first afebrile day different organs. There was no mention of controls. almost normal values had been reached. The clinical As Schmidtmann {Ibid. 32, 077(1930)) has ruled out As course and prognosis seem to be improved by the vitamin in the ore as a cause of the Schneeberg lung tumor, D. D therapy, although the no. of cases treated is not suffi thinks that in the mice as in the miners Rn may be con cient for conclusive proof. It was not possible to say sidered the cause. Harriet F. Holmes 7 whether the hypophosphatemia was the result of an actual The importance of proteins for the production of cancer. decrease of the blood P or a transfer of the P from an R. Reding. Z. Krcbsforsch. 47, 240-50(1938).--The inorg. to an org. phase, or reverse. E. M. Humphreys theory of cancer as a local process and the opposing Creatine-creatinine metabolism in congenital myotonia theory of cancer as a general constitutional disease may and the effect of glycine and prostigmine upon it. Josef l>c brought in line by considering both as due to protein Dicckhoff. Monalsschr. Kinderheilk. 73, 1-10(1938).-- intoxication with protein-split products. A focal break Two cases of myotonia congenita in 2 sisters aged 2'/i ing down of tissue under the influence of hormones or and 4 '/i years were studied under a diet free from animal certain chronic intoxications leads to a flooding of the 8 protein. Both showed a high spontaneous excretion of organism with protein-split products giving rise to the creatine with reduced excretion of creatinine. Addn. of general humoral symptoms of cancer, while on the other 15 g. of glycine daily to the diet produced a distinct in hand resorption of exogenous or endogenous protein crease of the creatine excretion, while the creatinine values split products may lead to local necrosis and proliferation. were not much altered. The spontaneous excretion of H arriet I1'. Holmes creatine and the hypercrenlinuria after glycine adminis Etiology of noma. C. Oprisiu, 1*. Kassay-Farkas and tration showed a relation to the severity of the clinical V. Jula. Arch. Kindcrheilk. 113, 108-71(1938).--In a picture. The muscular inefficiency was not affected by fatal case there was an increase of scroglobulin and di the glycine treatment. Daily injections of prostigmine amino N and a decrease in scrum albumin and urea N. 9 caused a decrease in the spontaneous creatinuuia, and also Eleanor M. Humphreys of the hypercrcatinuria produced by glycine; also creatine Transfer of agglutinins from mother to the newborn. administered at the same time was retained better. Under Ludwig Schneider and Gustav I'app. Arch. Kindcrheilk. the influence of the prostigmine the muscular weakness 114, 91-8(1938).--The agglutinins present in immune was transitorily improved. Eleanor M. Humphreys (anti-coli) horse scrum injected into pregnant women arc Alkaptonuria in an infant. U. S. Ruzieie. Monalsschr. eliminated relatively soon, but if the injection is made Kinderheilk. 73, 195-6(1938).--Of 45 cases recorded since shortly before delivery, the agglutinin value of the 1920, 32 arc apparently congenital, to which R. adds colostrum on the day of delivery is less than that in the another case. Most of the cases arc males, and fre-