Document yrLmN06gM3YZyV7v4rmMENqZd

r &S 109597 BlO-HEDICAL RESEARCH DOCUMENT DESCRIPTION FORM 63__________ 68 69_____________ 76 * Duplicate in all cards:--$> 11 oaoa24o year as-1961- File number (Right justify [Numeric only] Author (s), as Last Name FS (No Punctuation) and codea for journal as JAMA preceeded-by. one blank space 1 /J-T-Vo />!. 20-21 40 41 _____ cJ $ Ar S / 1 */ ,> M *r,/ . . 11 78 Sub-Index Code 60 61 62 * Title of Report: end vith space-hyphen-hyphen-space. Follow with Index Terms. separated from each other with .comma-space. Avoid other punctuation; ` do'not abbreviate. 12 * .. v . 61 62 *. --tt- , . 21 22 c- 23 - 24 turce (Journal, Vol., Number, Pages, Date) 12 ......................... ; ' : 1LL. " * .. ! cl/) '"_=/ f- '''--'3,*: tz, ~Z__i/if-,/-,' r?__ Xx /jo-57 -- i'1. / 61 62. 31 32 Brief Sur^^ry 12 10 SUMMARY: 61 62 61 62 63 64 12 H. Hocko, K. riepji At. Nosko, K. Pcrnov, .U. Spasovski -- Vinvlehlorlde Disease in Bulgaria . $?/>/* ' Summary. The authors followed liie concer.tralions of vinylchioride from the beginning its production till now during its synthesis and polymerization arttl established that..in >G5 they were 110 mq.rn5 but since i970 they were in the ranges of 12 to 2-10 mg.m* of the reshold value ot 30 mg.ntJ. - /r/S"' They undertook twice examinations ol 137 workers, including neurologic status, chan- s in hemopoiesis, protein and enzymic iunciion of liver. They discovered ten cases with vinylchioride disease and 19 with single syndromes. >c sick persons were mainly from the persons!, working during the polymerization ot vigyl- ioridc at the repair workshop with a length cf service of 3 to II years. Vegetative pofy- uropathy and increased activity of gamma-clutamyltrsr.speptidase were the leading signs, lere were acroosteolisis and thrombocytopenia in some of the patients. The authors prepare medical-prophylactic measures in respect to a 6-hour working day, ditlonal food without pay, preliminary and periodical examinations of the workers and itable labour establishment of the same patients. An experiment is carried out to correct reshold value oi the concentration. mens n sapaaeonarauie -- XX, 1977, ,\> 5 ;tena I zdraveopatvane -- XX. 1977. Na. 5 nocrj.mi.ia -- anyspit 1?77 Received -- January 1977 9OOn240 nPOMEMH B AJIEPrHHHATA PEAKTHBHOCT y JHEXAHH3ATOPH M. Je^iposa . -- Coijuis, ItHCTiityr no xirrueua ir xpauene. KniruiiKa no nr'C.beciioiia.iHU zaCo.iaBaHHa, pS.KCB. aou. X:, Uojoj Haft-xapaKTeptioTO 3a itameTo comia-ncTimecKo ce.icKO ctonattcTEO ca eco no 6T>p3inrc TeMnoBe Ha pa3BiiTiie c uinpoKO inno.iayBaiie na nocTiuKemritTa ita yxaTa it TexHHK3T3. C yejtpHBaiieio, c Me,xanti3amisiTa it xiiMitaaminra mv ce BfliiraT it peamia npo^naTo.iornqHif npco.ie.Mit (3, 5). Ot ext a cTpana, ce.icKo- onancKOTo npoii3nojcrBo Bee noBete ce jofi-iiintasa ao npoMimueHOTO, a, or 'Vra, to ce xapaKrepiiairpa etc cboh cnemrcJitiqHii ocoCettocTit -- it jutec ce.i- oaonaHCKHTe pafxmutmt ca lo.ioJKemi ita Bi.3aericTsneTo na KOMn-ieKC ne- .'aronpHHTHit Tpyaomi rJiaKToptt, npiiMepno rpyja na MexamraaTopiiTe. npovq- tuiiHTa ita Mttoro aBTopn tl, 2, 4) noKacaar, ve no 3pe.\te ita pa6oT3Ta cit Te `cto ca injiojKeiiti ita npocryaHii MoveHTii n npaxoso swaeficTBiie, iiaABimia- uuo JtecetKit nwit npe.ae.iHo aonycTUMHTe HopMit. Ffpri Tosa iiHxa.nipaHitJiT ot >x npax e c t(mita xicnepcaocT u ct>c caciseH cbcraB (MmiepaaeH h oprammeH), (aipwatu tiecTumtan, MiiHepanint lopo&e it to.ihmo Ko.uiqecTBo rtCtia (Juiopa. c.ieacTBite na pafxyma na MaiuiiiuuiR XBiirare.i bib Bwayxa ca H3Mepemt tuiaj- peac.uto AonycTiiMii KoimeHrpamui Bpeznir rajose (CO) it HetJjronpojiyiCTit, utywiT no Bpe.Me na pa6oia aocrnra 95--106 j5 c ejncapeMeHtto BtiSpoBM^efitmte aipxy un.ioTo ta.io i2, 4). *'c,,SKtl TC311 taKTopn Ha paSoTHaia eperta tie ca Sea 3ttateiute 3a 3ApaseTO #jnoai,HlaT0^l,Te'3a cl>CTOHI,,,eTO Ha HMyHo6no.iomi*3aTa peaKTiiBHocr, korto Mm r0*1*111"^6 nPH pea k uin: na npncnocoCHsaire c 0K0.inaTa cpejia. *pi ijwAxr* 33 ct,CTOBinteTo Ha a.iepriiHHaTa peaKTHBHOCT npn Mexawt3aKflC HC Ca nPaBeH,t- ^!le C11 nocTaBitxMe sa ue.i aa npoynitM to3H itAonpeac.-jajie jI3 piiCKa 3a 3-1,311 iiKBatte he a.iepro3ii epej rpyna or ^ R&S 109598 npoMenn 9 i.Tecru'iuaTa ;cjkti'shcc7 v ______ 70 AyuiH MexamuaTopit or arpapHonpoMitui.iemtH KOMnnexc b p. Kiieina. Or tbx 51 6sxa TpaKTopitcrti. 9 -- KOMSaitnepit it 10 -- MoftTboptt. BcHHKit 6a.\a MtHte, ksto M.iaatiTe itHTitsiaii ot 20 jo 30 roinmt 6nxa c.iaOo aacTtnemt (7,1 o). npeo&iaAaaaxa .uiuaTa b r.pa.ia 11 iianpcjna.ia BMpacT: J2,9?6 6nxa or 30 jo 40 rofliiHii. 40% -- ot 40 ^0 50 roAitHit h cbmo To.iKOBa -- 40%, ot 50 ao 60 ro/tHHit. Ha TOBa BtapacTOBo pa3npeae.ieinie Kopecnoiuitpaute it npoATwi/KiiTe.ihhht Tpyjoa CTant npn Tax -- 77,1 ?i HMaxa Hax 10 roTtmut CTaa; KaTo MexainiaaTopii. Ot thx 25,7?o ca pe6oth.hi ot 10 xo 15 rox, 40% -- or 15 ao 20 rox 11 11,4% ca H3ni.iHiiBa.iti npc4*cimTa ca noBeie ot 20 rojimn. ` 3a ocitnecTBRBaHe Ha HamaTa ue.i ocbch noapoCitata anaMtte3a bchhkii nima 6axa K.iHHiiqecKtt npemejann ot cneaiia.iircTii n KOHcynTiipani! c thx -- Kapxiojior, o4>Ta.TMo.ior it oTo-pitEo-.iapitHro.ior. C no.Motirra na cnitporpaij) 6nxa 113cjieABanii noKa3aTe.iiire Ha BtHiuitOTo xtiinaHe (BK. CEOBK, 3LMB), a 3a onpeaeJiHiie ciCTomiiieTo na 6poHXita.maTa peaKTHBHOCT Seine npn.ioHiett iiuxa.iaTophhht aep030.i0B aueTH.ixo.i;:HOB Tecr npn aiinara Sea t()yHKUH0H3.111 n aaitmt 3a CpoHXOoCcTpvKmiH. npo.MtH?! b a.iepn)4H3Ta HM peaKTHBHOCT TtpcexMe qpei K03KHoa.ieprnHtio TecTVBatte e na6op a.iepreHH -- Chiobii, CaKTepiia.itnt, riGiin it noJieHOBH. C H3K.iioqeHiie Ha no.ieitoBi:re a.iepreHit, kohto an.imnipaxiie cKapn(fmKamtoEHo, ocraHa.iitTe nccTaBHXMe itHTpaaepMa.iito. KoHrpo.itntHT tcct mt cjiyiKeuie 3a otreHnsaHe HopMa.maTa Koxna peaKTHBHOCT. BctmKtt Ko>KHoa.ieprHHHit peaKuitit oTHttraxMe ^syeTanHO -- Ha 20--30-ra Mtiftyra n na 24-un qac. IlojiyHeHiiTe aamin cpaBHEsaxste c aaHHine Ha KottTpo.maTa rpyna .lttua, ita6ponBamii 30 jyuin axMiiHitcrpaTitBUJi c.iyjKHTe.m c noao6no m>3pacroBo 11 Tpy flOBo paanpeae.ienite. Peay.iTaTit it o6ct.itaaite AHa;-:He3aTa it K.iitHtit7HnnT nper.iea noK23a.xa, ne Mexamt33ToptiTe Ooneay BaT no-necTO ot kohiohKTi.'Bimt. KaTapii na ropnitTe jiixaie-ittn niintua 11 6poitxiith (Ta6.i. 1} B cpaEiteHite c KOHrpo.iH3Ta rpyns, ksto ycrattooeHara pa3.ntKa ce 0Ka3a CTamcTHHecKit aocrcsepKa (p <0.051. Tean jantta 6axa b no.iojKHTe.ina KopeJianiBKa Bpi3Ka He Tcr.Kcaa c TtoTtoHonyx'cHeTo (BinpeKit qe noBene ot noJioBiHiaTa -- 54,3%, 6axa rr.2:2111), ko.:ko7o c npoji.iHjiJTe.ii!ocnaHaTpyAOEmi CTaxt. T a (5 ji u U a I 3ado.-iseum.i Mt.'^naitorrr { KoirrTxv.aa rn'na KomoHKnrs; tit ripeKapaHi: lurapu a rjri EpOHXliTi! PeniiuiTi: XirepuK: a HeBpacTiF.eK r; njpcJt f. 6`"'n i7"'i .4% .?% 3* %*. 10".. 3.3% :0% :on., 30% C noMOtUTa Ha KOKHCE-TcpniiHOTO Tectyaane 6eute ycTaitoBetto, ie 48 ot tux (68,5%) ca a.ieprniBB. xaTo c.iyqaitTe c no-mcenctidii.vijautiH (45,7%) naABiiuj33ax3AByKpaTHo ciyiaiiTec MOHoceKc;i6n.iit3amiii (22,8%). rio.iyqeiiitnT