Document yrGygaQKmkbdb0JZmJ610zJ2d

tudy Number A-15 A-19 A^" ? Laboratory Scientific . Associates Scientific Associates Scientific Associates A-91 Scientific Associates . 'BIPHENYLS SCIENTIFIC ASSOCIATES AROCLOR STUDIES l FQR IDENTIFICATION f /-/ * DATE: ' Author . Completion Date Polychlorinated Biphenyl Product Description Fred M. Younger 11/10/53 Aroclor 1254 Oral LD-50 . Fred M. Younger 12/11/53 Aroclor 1242 'Oral LD-50 Fred M. Younger 1/13/54 Aroclor 1248* Oral LD-50 Inhalation Study Eye Irritation Fred M. Younger 2/3/55 OS-63 Aroclor 1242 48%* Oral LD-50 Skin Irritation and Absorption Eye Irritation Vapor Inhalation -57-22 \ -62-34 -62-35 -62-36 YOUNGER LABORATORY STUDIES AROCLORS AND AROCLOR ELENDS Younger Lab Fred Younger 7/9/57 Aroclor 1270 ' Younger Lab Younger Lab Younger Lab Fred Younger Fred Younger Fred Younger 6/19/62 6/19/62 6/25/62 Aroclor 1242 Aroclor 1248 Aroclor 1254 Oral LD-50 Eye Irritation Skin Irritation Oral LD-50 Dermal LD-50 Oral LD-50 Dermal LD-50 Oral LD-50 Dermal LD-50 vDenotes Aroclor Blend. WATER PCB-SD0000037152 udy Number 62-37 Laboratory Younger Lab 62-38 ' Younger Lab 62-41' Younger Lab 6? ' 2 Younger Lab 62-44 . Younger Lab 52-52 53-11 53-12 Younger Lab Younger Lab Younger Lab 63-88 Younger Lab Percent Shown for Blends. Author ' Fred Younger . Fred 1 Younger Fred Younger Fred Younger Fred Y' o u1 : n. g..er. Completion Date 6/25/62 6/25/62 6/13/62 6/13/62 7/3/62 Fred Younger Fred ' Younger ti Fred ' Younger ! 6/6/62 3/4/63 .. /t 3/4/63 ' Fred Younger 12/19/63 Polychlorinated Biphenyl Product Aroclor 1260 Aroclor 1262 Aroclor 1221 Aroclor 1263 Aroclor 4465 Aroclor 1232 Pyranol 1470 Inerteen PPO Aroclor 1242 74.8%* Aroclor 1221 12.4%* Page 2 Description Oral LD-50 Dermal LD-50 Oral LD-50 Dermal LD-50 Oral LD-50 Dermal LD-50 Oral LD-50 Dermal LD-50 Oral LD-50 . . Skin Absorption Skin and Eye Irritation Oral LD-50 Dermal LD-50 Oral LD-50 Skin /-.bsorption Oral LD-50 Skir. Absorption Skin and Eye Irri t ion Vapor Inhalation Oral LD-50 Skin Absorption WATER PCB-SD0000037153 y Number -49 Laboratory Younger Lab -214 Younger Lab -151 Younger Lab -164 -105 -12y Younger Lab Younger Lab Younger Lab -133 Younger Lab Author Fred Younger 1 Fred Younger 1 Fred Younger j Fred ' Younger Fred Younger Fred Younger i Melvin Birch ercent Shown for Blends. Completion Date 6/13/64 \. ' * 1/12/66 . .. 10/17/66 11/9/66 10/19/67 1/13/69 1 i. . 1/22/69 Polychlorinated Biphenyl Product Therminol FRO MCS 29.5%* Arcelor 1254 10%* Aroclor 1248 43.7%* Aroclor 1242 37.7%* Aroclor 1232 6%* Aroclor 1254 10%* Aroclor 1243 43.7%* Aroclor 1242 20%* Page 3 Description Oral LD-50 Skin Absorption Skin and Eye . Irritation : Oral LD-50 Oral MLD .Skin Absorption Skin and Eye Irritation Vapor Inhalation Oral LD-50 Skin Absorption Skin and Eye Irritation Vapor Inhalation Oral LD-50 Skin Absorption MLD Oral LD-50 Aroclor 1248 Fluorinated Aroclor 1254 Oral LD-50 Dermal LD-50 Eye Irritation Skin Irritation Oral LD-50 Skin Absorption Skin and Eye Irritation WATER PCB-SD0000037154 ly Number *-41 Laboratory Younger Lab *-42 -5j Younger Lab Younger Lab *-54 Younger Lab f-74 Younger Lab 1-116 Younger Lab -14 Younger Lab Percent Shown for Blends. Author Melvin Birch 'i Melvin Birch _ Melvin Birch Melvin Birch Melvin pirch .1 Melvin Birch ' Melvin Birch Completion Date . 5/5/69 5/5/69 7/7/69 l i .. 6/30/69 8/17/70 1 'i 12/14/70 2/14/72 Polychlorinated Biphenyl Product Aroclor 1242 3C%* Aroclor 1242 40%* Fluorinated Aroclor 1254 Erominated Aroclor 1221 Aroclor 60G2 Aroclor 5460 56%* Aroclor 1221 34%* Aroclor 4273 - Aroclor 5442 73%* Aroclor 1221 27%* Aroclor 0114 Page 4 Description Oral LD-50 ' Skin Absorption Skin and Eye Irritation Vapor Inhalation Oral LD-50 Skin Absorption Skin and Eye Irritatio Vapor Inhalation Oral LD-50 Skin Absorption Skin Irritation Eye Irritation Vapor Inhalation Oral LD-50 Skin Absorption Skin Irritation Eye Irritation Oral LD-50 . Skin Absorption Skin Irritation Eye Irritation . Oral LD-50 Skin Absorption Skin Irritation Eye Irritation Vapor Inhalation Oral LD-50 Acute Skin Absorption Skin Irritation Eve Irritation WATER PCB-SD0000037155 udy Number 71-105 Laboratory Younger Lab -71-187 Younger Lab 71-189 Younger Lab 73-150 Younger Lab 74-54 Younger Lab 74-55 75-0252 Younger Lab Younger Lab Percent Shown for Blends. Author Melvin Birch Completion Date . 6/28/71 Melvin Birch t Melvin Birch 1/12/72 1/12/72 Melvin Birch 9/17/73 : Melvin Birch Melvin Birch 7/10/74 6/8/74 10/22/75 Polychlorinated Biphenyl Product Aroclor 1272 Aroclor 1016 44%* (German Mine Fluid) Aroclor 1016 43%* MCS 1489 /> Aroclor CL016 Aroclor 1016 Aroclor 1242 Aroclor 1016 Page 5 Description Oral LD-50 Dermal LD-50 Eye Irritation Skin Irritation- Oral Lethal Dose Skin Absorption Skin Irritation Eye Irritation Vapor Inhalation Oral LD-50 Skin Absorption Skin Irritation Eye Irritation . Oral LD-50 Acute Skin I-.bsorptior. Skin Irritation Eye Irritation Vapor Inhalation Tissue Residue accumulation and depletion study in rats Tissue Residue accum. lation and depletic study in rats Oral LD-50 Dermal LD-50 Eye Irritation Skin Irritation WATER PCB-SD0000037156 r ay c u tudy Number C-62-0004. INDUSTRIAL BIO-TEST LABORATORIES, INC. AROCLOR STUDIES Laboratory Author Completion Date Polychlorinated Biphenyl Product Description IBT Richard J. Palazzolo 1 3/28/63 3/27/63 3/4/63 3/29/63 3/28/63 5/17/63 . Aroclor Aroclor Aroclor Aroclor Aroclor Aroclor 1221 1242 1248 1254 1268 4465 Subacute dermal toxicity in rabbits T-69-0033 IBT r-70-0016 IBT r-7l-oooi IBT 1^. '-0067 IBT T-71-0068 IBT T-71-0069 IBT Carmen M' ast: ri i1 James L. Stephens Carmen Mastri Dale Fletcher Sandra Haley Philip S. Smith 6/13/69 6/4/70 t ` i 3/25/71 1 6/15/71 11/1/71 11/1/71 11/4/71 11/12/71 Aroclor 1242 Aroclor 1254 Aroclor 1260 Aroclor 1242 Aroclor 1254 Aroclor 1260 Aroclor 1016 Aroclor 1221 Aroclor 1242 Aroclor 1242 Aroclor 1254 Aroclor 1260 Aroclor 1242 Aroclor 1254 Aroclor 1260 96 hr. LC-50 Toxicity reproductio and residue study in white leghorn chicko Oral LD-5 0 Dermal LD-50 Eye Irritation Skin Irritation' Vapor Irritation Toxicity reproductio and residue study in white leghorn chickc Three generation reproduction study in albino rats Two year chronic oral toxicity in albino rats WATER PCB-SD0000037157 ndy Number -71-0069A Laboratory IBT `-71-0070 IBT -''l-OO?! IBT -71-0072 IBT -71-0073 IBT -71-0136 IBT u72-64 IBT '-72-0082 IBT -7^ -0103 . IBT -72-0129 t- 7 2 -131 IET IBT T - 7 2 - 013 3 IBT Author D.E. Gordon Bruce R. Burtner James B. Plank James B. Plank James B. Plank Dennis Arnold John W. Goode Kenneth Ebbens John Hamlin Unknown Completion Date 3/24/75 11/1/71 9/8/71 9/8/71 9/9/71 1/13/72 1972 11/17/72 1/12/72 12/30/71 Polychlorinated Bipheny1. Product Aroclor 1242 Aroclor 12 5 4 Aroclor 1250 Aroclor 1242 Aroclor 1254 Aroclor 1260 Aroclor 124 2 Aroclor 1254 Aroclor 1260 Aroclor 1260 7\roclor 1260 treated Aroclor 1242 Aroclor 12 4 2 Aroclor 1254 Aroclor 1260 Aroclor 1016 Aroclor 1221 Aroclor 1221 Bruce R. Burtner 12/31/72 Aroclor 1016 Page 7 Description Re-evaluation of original report dated 11/12/71 Two year chronic oral toxicity in beagle dogs Teratogenic study in albino ra Teratogenic study in albino rats Teratogenic study in albino rats Mutagenic study in mice 4-Day fish toxicit studies 96 hr. LC-50 96 hr. LC-50 196 Hr. LC-50 90-Day subacute oral toxicity study in beagle dogs 90-Day subacute oral toxicity study i dogs WATER PCB-SD0000037158 idy Number -72-0134 Laboratory IBT -72-0135 IBT -72-0137 . IBT -72-0138 IBT -72-0139 IBT -73-0070 IBT W-69 . IBT Author Dennis Arnold Dennis Arnold Philip S. Smith Dale Fletcher Dale Fletcher i Dale Fletcher Gary . Rausina Completion Date 1/31/72 Polychlorinated Biphenyl Product Aroclor 1242 1/13/72 Aroclor 1254 4/28/72 Aroclor 1016 Aroclor 1221 6/20/72 Aroclor 1016 6/20/72 I 1973 1 ' ,-- Aroclor 1221 Aroclor 1242 MSC 1489 Page 8 Description Mutagenic study in mice Mutagenic study in mice ' 90-Day subacute oral toxicity ' study in rats Toxicity reproduc tion and residue study in white leg horn chickens Toxicity repro duction ar.d residue study in white leghorn chickens Toxicity and reproduction study in v;hite leghorn chickens 4-Day fish toxicity study s WATER PCB-SD0000037159  * # ^* * * ' 'MISCELLANEOUS STUDIES ;udy Number Laboratory ` Author Completion Date Polychlorinated Biphenyl Product -54-0050 Kettering Joseph F. 6/22/55 Trevon Frank P. ' Cleveland John Cappel Frederic E. Shaffer Raleph W. Atchley John P. Torbeck A.roclor 1242 Aroclor 1254 Monsanto William Gaf fey Ferdinand Meyer Judith Zack Incomplete Various . i Harvard Medical School C. E. Drinker i* 1937 i .. Aroclor 1268 Earnard Free l. k. : ' 1949 Aroclor 1254 Skin & Cancer Halpern Hospital V - Litton Bio P.' E. t Incomplete Aroclor 1254 . netics Berteau Page 9 ' Description Inhalation exposure of cats, guinea pigs, mice, rabbits and rats Mortality study of some PCB production workers Inhalation studies on rats Human patch study Pveproduction study in rhesus monkeys WATER PCB-SD0000037160