Document ypQjy46pnqZr55xyKDD48aXZn

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Kl CJ <r CM H* CM O' 10 $ p * H & # CM a O' rH -* 10 U<fh M to 10 cd JO 0* ] to 10 r~f O *o ro 1 o o j N o CO <0 *2 CM 'ff CM 4k N io *k O' IO A s> CM o k o JO O' >o 'O <0 H jo CM CO H CM JO * H CM UJ N M5 IO CJ rH CM !> CM * CM I sO 1 K> w io to 10 CM to fxN K) 3O' c? *0 o N JO co JO o H >0 >0 CM o X0 K *k H IO CM *0* IO <r CM 1.140 >DC s a i iu I CM M O' sr UJ > a 8 O' CM O' to UJ Q -s 3 3 <o CO to to 5> (O << LU CO & s < Htt s Xo g o CQ S < z GENETIC TOX -TECH SALARY CO sLU 3 O -> 5 <0 Q LU B gX to H- u 3 LU CD S ui gCO CL UJ CM X 5UJ as g bU O' H JU CM N a O' o M _J 3- % UJ LU XX w CM H aH IO LU X X < x O-l' 2UJ (9 61 . DUP050447744 38 DUP050447745 c cOo vh u pa <a utoj 3 o &CO UJ Ul o m o (0 ca o H h <0 o si* ;g s CJ w '3* eg *A N k 0 l-l w tM <0 r* 1ft LA O' O * RH * OO UJ h :a (9 aj i*. <0 to o <0 <t <0 r*t sr K> *S* IA D 2 IU 0 fe C<VUJ 1 O' o g O' K-t to CoJ UJ QJ K) DC LU U t> CM 0* ? w > 3 1 0 9J IU a sZ 1 1U1 iu a 3S gEL X gUl J Ul < w IU b" Ul a o i- Ul u. S'o Sto 3oCO < * DC LU oM UJ E eo u ? hi 8 i-J ui < CL a to Uato.l LotoU. o* o s o r* Q 1*4 lit < i z gw ID DUP050447746 XDDD03E3 PRTH953- DUP050447747 GENETIC TOX -TECH SAURY 38 1I40 DUP050447748 DUP050447749 (NAME) CENTRAL RESEARCH &DI^ELOFMENT DEPARTMENT " h a s iSl 'l 'La b o r a t o r y f o r t o x ic o l o g y Ap in d u s t r ia l me d ic in e <- DATE July 20, 1982 TO: K. D. DASTUR CHEMICALS & PIGMENTS DEPARTMENT REVISED B-6314 C2 nd) PROJECT MR- 2929 PART II TITLE: CHRONIC INHALATION TOXICITY STUDIES ON Ti02 and TiCl4 am tJQ mm Authority is requested to undertake the study identified above and described as follows: Two mathematical errors occurred in preparing the original MR-2929 budget (1. miscalculation of the lab assistant category under the "study" portion of the project accounting for $68,000, and 2. Incorrect application of the 10% per year cost increase rate accounting for $15,810). Both errors resulted in a cost underestimate of $83,810. . In addition, final study charges are anticipated to overrun the corrected study budget by approximately 9.4% ($126,190). This overrun is due principally to a greater than expected increase in inflation rate. The preceding items will account for a $210,000 overrun on the amount originally authorized. This Part II requests C&P to authorize funds in the amount of $159,538 which represents 10% of the original authorization ($125,538) plus one-half of mathematical error #1 ($34,000). No charges beyond those specified in this Part II will be charged to C&P. . V Amount requested _______ $ 159.538 Previously authorized.__ $ 1.255.384 , j * i^1 Forecast month and year Experiment to start _ Experiment to end ____ 6/79 6/81 Expended through Apr '82 $ 1,263,217 (date) General Ledger & Sub-Account to be charged Final report to issue 2/83 (TiQ9) 11/82 (TiCl4) Request for study made by discussion between J.R.Gibson and S.N.Bovd.Jr,, 7/20/82 CLASSIFIED: R&D D OTHER ________ (check appropriate classification) If this request meets with your approval, please enter the GENERAL LEDGER & SUB-ACCOUNT TO BE CHARGED and the CLASSIFICATION, have the original authorized and return to HASKELL LABORATORY, CONTROL SECTION. The additional copies may be retained for your information and distribution. Proposed by ~ / Y Approved bv. 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CO 1- r*. mCO CO noCO- i OHCO' mCO m mm in co w nm O c *H m F>. 05 i> in mm o <j* i N N* r* miCnO mrcso. m m wCN r- *o m 05 mCh H<0 ZOE H ZUJ a ** tXux * UJ : #> gp *E *a :5 UJ CO CO m in in in mm mco imn mo m O' NN r>* O' oo CinO iCnO mm o o iCnO m oo CO CO imn min mm o CO imn m to to to H H HCL CL 0. o 10 (0 10 10 UJ UJ Ui Ui Ui Ui UJ ao a D. & to 3 3 MM -J J H o. a tx DC or UJ UJ UJ Ia &% 3 CO (O (0 ss E ooo *9 tt <4 i i V) i ZUJ to X o << MM a tx ui Ui Hh mi < to to CO Ui Ui ui M x: u o a a n: a a w H M UJ UJ H>>> 3 tx DC a g g gg gocn S er UJ UJ UJ ut to (0 CO hh H to u tUoi tUoJ CO UJ CO ut to to to w id id CD ID "5 -> or nr or X a o o X << < < << < u XX 5u Ui a: o u XX X uu u tx at X tx a Ui tu < < *< g 3 Ui UJ CO to UJ to aoc xo X o L X tu Ui o: tx UJ tx uu u U 1t 1 aIU a Ui W P ml ml ml ml UI UI J UJ -_JJ UJ 1 ml ml UJ mUJl ~JJ UJ QL X X X X X X X P < <o X to to (O CO (0 to to M< < << < Q X X X X X X X DIRECT CHARGES 79-372929-129000-353000 DUP050447806 DUP050447807 PATHOBIOLOSY OVERHEAD 353200 3,335 DUP050447808 polyglots, inc. G0$7o I E,, I. DU PONT DE NEMOURS & COMPANY Haskell Laboratory Elkton Road . Newark, Delaware, 19711 "i P.0. BOX 5333 PHILADELPHIA, PA. 19142 13151 636-5000 L 6/5/84 fVOUB ORDER NO. LOGX5663 TRANSIiATION -- German to English OUR JOB NO. 77-262 Rosenbauer, K. A., Anat. Anz., Jenna,'Vol. 147 PP. 301-316, 1980. ' a 3800 words @ $6.20 per C J>RI & IfRM OK EXTENSION (NECKED imnjp- $235.60 JUNO1? 1984 mi r ec 'd isliP auiaui os s er v ic es r ec o okic, 5HY9 35 - 793 ~ 39- 3 9c ?9 3Lni Ho 9J99 * >> >9 9 999 9 N 30812.04 DUP050447809 polyglots, inc. o,ono\ r E. X. DU PONT DE NEMOURS & COMPANY Haskell Laboratory Elkton Road Newark, Delaware, 19711 "i ' P.0. BOX 5333 PHILADELPHIA. PA. 19142 (215) B26-5000 LJ DATE , 6/5/84 YOUR ORDER NO. S L0GX5663 TRANSLATION -- German to English OUR JOB NO. 77-262 Rosenbauer, K. A., Anat. Anz., Jenna, Vol, 147, pp. 301-316, 1980. 3800 words @ $6.20 per C APPROVAL PRICf 6 IXIfNSIQH 1 CHECKS IERM W. WWJfy $235.60 JUNO? 1984 *i ffic o (ofa> ma t e h u ot savins ut o o/ac^ 5579 35-3794-' 1"Jkanlt . y* 11 i , c't , V' ` DUP050447810 polyglots, inc. r1 E. I. Du Pont de Nemours & Co., Inc. Haskell Laboratory Elkton Road Newark, DE 19711 P.0. BOX 5333 PHILADELPHIA, PA. 19142 12151 626-5000 L. J OATS 4-19-84 YOUR ORDER NO. LOGX 5663 OUR JOB NO. 77-260 TRANSLATION: French to English. Le Bouffant, L.: Proceedings of International Symposium ... Vol. 1, pp. 227-237, 1970 - 4300 words < 6.20 per C AHftOM Russian to English: Gurova, A. I., et al.; Gig. T^d, Prof. Zabol., No. 3, pp. 53-55, 1976. Mtttt fr ItW-OJU tftUHSIOtl OK - CHEtflO WltHJO 1500 words (3 $6.40 per C *54 79 MAY 081984 >35- 37461 !{ Kim MAIR1U 01 StMiCU RK'O 35-a74<a-37-W3?-9&-6Z> '/*i*!G**+l * $266.60 96.00 $362,60 Zlkanh \ DUP05044781 to 8 p X CL <0 ui LA I N tO 10 03 H <t to to to iH CO to IUJ >0 CM to LA LA m co n CO Si* N si* hi N tt LA 0s o 0 *** s? Sf JD si* CO tO O*O4 H & 8 1si* 9 CO 1 * Es LU < X IS ** $ LA sO A Ah 8W LA O' 1A <0 A* UJ N a M3 CM g I N to eo CO 0* CO A* CO rt si* H <F to CO to JO to LA <0 rs CO A* to A. 0" sO sO H iH LA O CO to LA M3 rS H e o 0 N Ah M3 0* Ah to o pS CO o H iH sfi >0 to to LA LA N S r>4 LA 1A CO CO C0 to sF <F sF H r-t iH CA si* o* CM fi s UI < O *X `8 3 8 Ui 2 UJ OO QO CJ to to to LA UO to to oo O M3 CO CM LA LA to to oo o CM CM K1 f0 fO LA JO (0 <0 to uztni u0.i X UJ u. o to z o H facr H XX CJ s s to UI w _J L Q. X to *8 to tu H -1 n. a. X to *8 to UJ M -J a a. X to etf to UI w J X X X to 9 to tu M -J 0. a. 8 * -J < fe Ui X JX Ut Q S g O 1 H X UI a X tu jE o 1 1X UJ a a Ui g o i z (0 03 < M < H J < M J < H -1 < W fe UJ z (0 to UI Ui o (J (0 UJ u 3UxJ CO a o X LU H < X UI J< K UJ H < X IS < X UI H< B. M Xor H > X UI M > CK UJ H > tx UJ X S r S z Z UJ to to to U <0 W UJ (0 to Vi to h* K to (0 H to u w C9 X LU UJ O 19 ut ID UJ to XX o *5 X *o O o z < X ! X eg O D C5 o < x <X <X < < < < X to IA 3 8 uu z aa Ui u j u XX uu X o V1u) to I X X < X< UJ LU <X UJ (9 X *t o o o X U>I isH sO c0 za Z O to to Ut UJ to UJ X u MT CM o XX X ri X 1o uu u u 1 1 u CA H etc 1 i I I UJ CO Ui _j -j -J -J -J -J _J X M CA CO o H Ui U! UI UJ ill UJ D N h o w I tn < t<n t<n Q u XX X m^ to to < x x< CO < X to UJ fZ CA Ui Ah CD DUP050447812 N 30812.05 DUP050447813 CENTRAL RESEARCH A DEVELOPMENT DEPARTMENT HASKELL LABORATORY AUGUST 1984 PAGE 260 s N o* m CO to Q IO H n <o o 4 cu H K) 43* CU 4 P ift 40 w CO i-l m OJ 4 1 sN CO CM 4 H 40 <0 Om 40 mm r4 ON n m JO H el ^8 h- I h <r oH O- XH p 2: o< P< <M uH tLoU s gg "1 Ee w 0 :g *U sr O' CJ N to S m n o m G, XU(zUaU0JJJ H >U_Jl -1 < mJ <CO XuU11J- 3UXL>QoUCl w >UmJI >a": <-<COj N s1--* t<o HXuUl 5 O LHQU 31KU O(J <tCLD HO LU 3 s uO. 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CM H rl CM CM CD 10 & CO O' rl > a 1 i 2U < DS :S U O iH CO No Ip O (0 CM 'O CM o IP I* i<r Q ip to IP IV IP I'Pt M3 CM O HO <h CM CM0 K) o <r *sr O' O IP CM M3 O M3 CM N CO o o CM P *0 O' O' to o IV H CM 'O 'D CM tNo to CM CM O H CO to O' Kl CM IP O' tv hi uH Hi O Xw OH zz o< HI H CM 3S < I- Sb O (0 Hi UI ZM oa cx a XH (J (0 vO K) CM *CO CM CM fv 5 9 F: CO 8 i-l CM 40 CM CM >0 ooO o K o H H CM IP to IP IP IP Aft ip IP Kl O IP CM IP IP IP <0 <0 O' CM O' K> fe Oaf x UJ a x UJ o to >- H- X 9 w> UJ <5 UJ X a UJ > o to UHJI Q 5 P (0 UJ B E Eo < aJ -J < to UMVJ) to Ut B O < Xu 1U )to UJ Hi CP UJ B o < o <UJ X OUJf > o > > o--toJ o Hut X o H* > U-JJ J <c to 1 > ID O-J o oHi X Ho > .UJi -1 < to 1 > CD ou o uHI X o3- < to X uUJ H" 1 >_oCDl o uHI X O 1- CD UJ O HI > Of Of V) > o > o 3 < in < >o u UJ H O UJ X a uj > O > z H *J > a < -J < (0 > z H X h > z Hi _J < UJ Of Of t DUP050447834 DUP050447835 PROJECT 372929 AUTHORIZED AMOUNT 1414922 CHROMIC INHALATION TOXICITY STUDIES ON T I0 2 AND TIC14-CD&P 4D < to <o o o: uj to 2= UJ o UJ 3 fL O >- U >- H 1 Ct w <t* O O r-4 }* H U < XM DS o t- OH to < Z .J o < M -J t- CM -J < 111 -J M 2c: < H to X < zz X HO O (0 M LU So Ha o: 3 XH U Cl) uj iE :2 ? 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OH xfr fe o u o Itf -1 X -1 H wZ to o s tz * U1 tt a *3 u to x> to O' X O' to to to 0 C0 id i-f CM tfl CM <0 IV r* to IV 1-4 to 0 to O' xO H r-4 X0 T-J to x0 to xO o CM CM O |V O' *3- CO sO to ON o id I c m O' r-f CM UJ .H < Q to ao 3H a X *o a *3 U 3 o CO oo oo CM CM Kl tO Ifl L0 < M o o CM tO tfl Kl CM CM to to Id id to to to id to O 8 to W }-- t-- h >- H# S3 3U) to s 5X g<0 !z IU s to UJ H -J CL CL 3 CO to IU M J a a 3 CO 5 X to <0 to to UI UJ IU IU HI _J 4H H4 -J _1 H _J EL XL CL CU 5 55 5 CO to to CO *3 *s tt a -1 u ~J < << < H W 1-4 M tt tCOL or UI UI UJ u j H< *<z *<z i-- < X xx x p a UJ a --I < Ui 3 zF IU o Of 1 to UJ UI Xo CL M f3c* > p: & UJ IU to UJ 1--* z H g nJ < Xw z >3 U 2 M H a XL IU a o M a CD iU CD SI HI b >a HX Qo ta V UJ i3 UJ a to o< uX UJ CD b a X o u 1 u IU to < X T> 3 UO on OS << IU UJ V) (0 IU IU a; a it 3 j 3 -i IU UJ to to << XX -> to Ui B J UI to < X L> o o o lO id to * o o o xtf CM r4 1 O' CM O' CM JV to 1 O' a < UJ X a UJ > o X p H- UHI -- UJ z IU to a 3 < to X o LU H* 1 X o h g H4 t-- UJ z UI a a < IU X a IU >o iE CL -J IU -Jl J < (0 iE C CL -J < O M zHI o < o DUP050447836 DUP050447837 M5 ILl rH * H- K <a tu o I Kt O' ON o UI hN in 8 w O' 2E yg O' o <0 M a -E in N9 ui Q W a. <* >-8 > Ot m -i* 8 hs 2 oP O Q < 8^ H CM <o UI ~J HI <H Xz z X MO u in M IU ZH S X I-- o 0> H z IU K I tu o O' cu <0* 3 tu > UI a X I UJ <0 UI os io * UI 3 <0 in >ino to fH CM CM in 8 -J x -J H HZ IQ g Z iu a i O' MD O' fC 1 rv -4 fH m H O* sO O' fs o in co O' CM O' CM m > i o U! in 5 UJ m ou X IU o H- IU izn _j 19 IU ou. ns CL O o X I- H UI tn ac os CL Ui z < u. 8Ui fe 2 jc UI Jl O < UJ O D-6148 CR&O ACCOUNTING DUP050447838 fO LOD' ro IU too Q Q S 0* O' CJ < N 10 CM o CM N 0 O' o O' *0 IO 10 8 H 10 CO N CM CM r* to o N $ro H vO o O' <0 ro ro N ro H o O 'y 10 CM -6 <r H ro ST o CO O ui I O' <Ha S H I ro COO' Is uz IO ro g 5g *> IO M ;& UJ i tt is ie I ift 10 oo <0 CO H H I ro CJ *0 O' rO IO K CM H It) CO N o h. * o sO <0 HO 0 CM CM w i-** ro HO N CO 0* H sH W 10 N O CM 10 >- f- 1 H Mf o H* (J H H (J xw XoCD OK HZ 3 o< -J ui 35 X < h* to X < 2Z X HO U (D * fzc * Ui Qi :S U , to gj X 0 CM 10 IO O 5 GO ao CM CM ro ro 1ro0 1ro0 G e rCoM to 10 IS in to <o -a- co CM oo eo COM *C0M 10 10 IO 10 o o MCMD in ro oe eo CM CM ro ro in in ro to o o CM ro in 10 o o CJ UD.I 3838 1X to UMI -1 X a to UI H mJ CCL. tUoi w CL CL (0 CO Ui UJ M-1 H mJ a cl aa to ui H mi a a hi O OS Ito & << HH oc ui b kit ee ui OS OS au iu a Ui i i s H K H K UJ (0 o o o ro o V a 3 < O < IU w H IU CO in ro < UJ to X a UJ i X X UJ -J to e OS u > < so o Ui > Ui H o to 5 <r CM l ss h* B H (S' CM X H X 5 < a mJ < a _) XM O' CM U H U H c u IT) <r u> o UJ UJ tt o s&p 35e w j < J2 I 3 si s DUP050447841 D-6148 CRfiO ACCOUNTING <0 * H w S inCM < N HI CM O CM IS O- * cu CM ki w w to n rs to m O' n O <0 Ifl <0 HI Hi Hi 0* Ul MS O MS HI 0 0 HI O (0 1- 0* CO in < H *0 <0 0. * fc o o s $X O' GS x <e W IU 1 HI C in CO is is 0* M) jh sO m rM-l * tu :5 O J- tfi o u s djE S OS II <1 CO *0 <0 O' H W hini CM HI f<s0 m n HI rC ri 00 M5 fH H M* int 0* CO HI MS *in3* CO O' i*n0 w to co H K 0 *0 IU 3aUJ a fe IsCOUL: w>IU CCOMM' sr M <r H a X0X CUXLUOi _<XhXJ- t0u CfOCOsMM'' to I- u*a0x1i a. jg OUNil Wx0X 5 < >4 U0J 50CO 0iH0Cn*MI' tu gUi txi us tu tDuC 00CIiHOnMI H1H00CM0>I H0OCiHnMII Ci000nM tO 00MCiHnMI 00i0CnM to H00CiHnMI H00CHinMII HC00KinMI ui sUCLi Xui tu O to 5 USUJJ J UJ 0IMaraDsJ).. to 9 <H DS UI tz MCI--E3ECUOOLLI 9 <XMUhJ* g CUOJ H--Ca3COL1. 4tf .<HXIUJ* H 5 r CUOJ CLUO 33 O5ECOL* 5C3COL- 0 tf -<J ~<J WXLHU* HIXHU << CIDO H_CCJLL 3 >UXHeHI < X-<HZU4I HZUI 2 M i ID CCJUaOLJr XUI 1 1 CIODO H>X UJ to LU zg<LU 5<Hz* _rJc H z < *% zCuH<O XuzUI ID CMO- HXaUI 0MO3 XCU<uXCOOI MCO MWO> XID "txLj u CUCO0I CIODO 99 uu Xx ui u j 1fcr 1fer _00~2ID1J*i -00DUz1jJ <0 40 << XX CUX<X0(9OI XUI 2 u1 JmJ Xu i to < X <XCUtoOJ 5 XUKJ Og DXVLCMUO < X HH L ssOc <3 n<Cgr XXX0<UCUOJI XXX<uItUUoI g X3UtUoIi )1 1 D I^D .--UXJ1i to to << XX JUi id to < X I1X<XuCD3O 1uUX-J HO OOO tino 0t00sCr<COo411MM>f' CISM to O1* N 9IXXU>0DI X0p> u Hh1U z Ui CD 3<CO X0IKU1> x0h 0 H|U-J z ui CD X9U>XIODI s<a. j<uH zH u H H >U~JJ mJ CO s _<tHjrj ^zHi U DUP050447842 DUP050447843 o cu tu U CD P a 9 >- j =S i U *4 MU XW I O t- CD 3 w H* M 3S US 5 x H < MO U (ft H 111 Zw Op a5 xP U (ft 5 Ift CD in o o h- CM in in jH 1 CM 1ft O* O <0* N O' CM o CO o in CM s * Of 0 :g *u <f <r O' o <r o j & s?o CO N IOft' <0 N c* A 9 N M <tf tf- s u o w -J X -j H MZ CD O CO O' O 1 O' >0 O' t CO O' o :g a w :5 o (ft Xo o CM CM CO X o z Oi K S3 1ft CM H *o CM CM CM CM <0 (0 ift Ift CM CM H O' CM O* O' 'd* o* JS fft o e o u < (0 ,J LU o K(fUt IX J- X m <# 8 a. X i tOg M K ID ID a. < .3 p 1 (ft 8 $ O' Ift m CM O Ift a- DUP050447844 D-6148 CRSD ACCOUNTING 8Kl p co N UJ I I UJ :S ro eg Q CM :p sO CO *0 C*iHM Kl C<iHAH0 Kl 8 NKHIl H<6 S' 1A0 OsKl KCKiOl OCM KJoOl o1f-04* CO IKHAl Kd*l j-t KOtol H ssO0 po-t Kl 0 Kl CoO o <1* Cf CrM. CnM CaIM* j <j- o fc UJ Cft tu So KCMl CrvM p cf tC*ooM s10 oHCM* KtCoMAl KCr*Ol. Kl Kl 15 pH $CM Kl v> CIO o ar* Kl ats * CKKMll IS o <Sr <cr <r CK CM K Kl :5 in i ee CehMi oCroM Kitrl uKli e CM K) 1K0l UJ a UJ DZ I to CO (0 CO UJ UJ tu UJ M MM M UJ o a CL CL a. QL < Ui CL n a 3 XL CL 33 a. 3 P to CO 10 to V) tu O X 9 1 fe 0 < <t < tu tu I HM Qt OS W fit sfi. U M UJ UJ tu H > f-r 3 at s <c cr tu X SC s UJ 0 OO M> 0 CM CM to 10 IO 10 O O M3 CM 10 Kl OCKtKoM)l KKOCtoM>l (0 I-- H UJ ss 0 > 3 J Kl %5 I gg UJ UJ tUoJ CUOJ tt X <J UJ to UJ DC 0 K < 10 Xo Xo I I ~J 0 JJ HH u j tu UJ 0X gg XX 3 <J u < < H WU u h hM t--i a UJ Z z Z ZM H UJ 1U -J _l 0 0o o DUP050447845 DUP050447846 DUP050447847 uj 1 10 CO io 3 1 C HI *O 0 OJ 3* CM "O O' to 0 0 10 H 0 0 fS CM CM tv 10 N pH 0 O rH rl CM n CO 0 o z o a 0< sr r-i O O 0 1 tt 3 U K) 5O5' O' 0 iu 0 i -a* O 0 H 0 * 3 <0* 10 o o *o * M) o CM 10 10 0 IO CM O' <3* CM o W Ifl H <0 O' O' H Ul - 6 to CM * o CM IS o H <? O' i a* to to to H rl 0 0 fs CM CM fs IO 0 t? 0 W0 O0 CM to 0o & U>J H Ul 3 o oo oo CM CM fO 10 10 10 10 to to 10 to oo ee M> O CM CM 00 to to O o o CM 0 to oo oo CM CM to 0 00 00 O O CM 0 0 0 Ul 0 0 0 0 0 S LJ IU UJ U bJ M M tH W IH Ul ~1 -J .J _t _ k a. 0. a el XL CL CL CL CL CL Ul X 3 3 3 3 0 0 00 0 u. o * eg eg <C eg Ul 0 K uj g CO mJ mi --jJ --Jj ii to fe < W <c M <M <IH <C M bJ U BUJ B Ui BB UJ UJ XX Ul H > h- t- t- H H X 22 2 ui <0 CO u0 < X B CO M> CL ur o So H CO u I- H 00 00 B 0 -> o g 0O << 0 < O3 tO 0 X 0<0 X 55u X 0 0 Ul tx 0 Ui I X X x a << sfr o 00 CL Ul Ul ui u CM KB XX . I ChM iH OI ' X JO-- | 2 22 .0 -J B CM O' <J L> -<J -<J j.<_ * M CM M t* y u - u or^ H t-- H M VH 00 0 << - 0 Z XZ Z IH M IH 0 -J -J -J 0 U UU DUP050447848 DUP050447849 o sO m oX o T3 VI M N O -J *0 : Xf m 3: * vl o e f ia r* 3o 8 m o H U v| r 0) so m s > m $ o 4S U >o 3 Nm ro o m -o tfj g c *5 M mm co o am zs -H > SC P HO ah wn 4> M lH 8"* Bo TJ wt w o 9 I -I m C c H cn O' w s* O > 3 69 m Vl Vj D-6148 CR&D ACCOUNTING DUP050447850 i5IA IA IA 1 Q CM <r i o* m m 0 H Id 9 N CM CJ N n o <0 K> K> m <0 s a* IA M> o* r <6 i ae ou FO CO O' H in IA o O' O' Ho r< CO o :I fO CM CM h h. KJ O M3 H CO CO CO o O' m CM H CM a sr iH H CO H N s IA O* CM O' fO CM oe CM CM mn IA IA W io o CM m IA rt M3 CM CM IA IA *t in M3 CM O' Sf CO CM UJ ct k5 _l 1U to to ui UI 5HM -J -J D. n. L S a a. IL o tO < s111 u M g fe sr to to UI uai w --I D. a. i a to ui u ui to 3a 5W 5 Ui 1 z l&J a o 10 IA to 10 Ui I O' CM h* 10 > 3 9 >>< < Ui Ui ui to to X g sUi 3 c <t to to u h x o; I K i <a <x <a. >* m _J J < < < < -J o u H uM uw oH z z z< H H H tt J J <J UJ U UO DUP050447851 DUP050447852 CENTRAL RESEARCH & ^EVELOPMENT DEPARTMENT HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE TO: K. D. DASTUR CHEMICALS & PIGMENTS DEPARTMENT B-6314 PROJECT MR- 2929 DATE PART II July 20, 1982 i REVISED (2 nd) TITLE: CHRONIC INHALATION TOXICITY STUDIES ON Ti02 and TiCl4 CKR JGA EGG GEB UD 1NHO Authority is requested to undertake the study identified above and described as follows: Two mathematical errors occurred in preparing the original MR-2929 budget (1. miscalculation of the lab assistant category under the "study" portion of the project accounting for $68,000, and 2. incorrect application of the 10% per year cost increase rate accounting for $15,810). Both errors resulted in a cost underestimate of $83,810. . In addition, final study charges are anticipated to overrun the corrected study budget by approximately 9.4% ($126,190). This overrun is due principally to a greater than expected increase in inflation rate. The preceding items will account for a $210,000 overrun on the amount originally authorized. This Part II requests C&P to authorize funds in the amount of $159,538 which represents 10% of the original authorization ($125,538) plus one-half of mathematical error #1 ($34,000). No charges beyond those specified in this Part II will be charged to C&P. . Amount requested$ 159.538 Previously authorized $ 1.255.384 Forecast month and year: Experiment to start Experiment to end 6/81 6/79 Expended through Apr '82 $ 1,263,217 (date) General Ledger & Sub-Account to be charged Final report to issue 2/83 (TiO?) 11/8$ <Ticl4) Request for study made by discussion 7pooloo- 0005*?g between J.R.Gibson and S.N.Boyd.Jr., 7/20/82 CLASSIFIED: R&D 0_ OTHER _________ (check appropriate classification) If this request meets with your approval, please enter the GENERAL LEDGER & SUB-ACCOUNT TO BE CHARGED and the CLASSIFICATION, have the original authorized and return to HASKELL LABORATORY, CONTROL SECTION. The additional copies may be retained for your information and distribution. Proposed by H. J. Trochimowicz HJT/cgs - 7/20/82 (date) DUP050447853 t'S8z**ogodna nH 0m o r* i- n p" o p* o in mm -4 a w MHHZZ 1 z z5 z Z m m Ui Hrj w H w H t OO O ft O o H w N r* > > 3> 3> o O 8 r* m r* r* N H H s> q >-< a a a a O o I >> >XXM o 5* 3 s IN* *< m tAa -* 0) o 1 H m Q < m o o > 33 X m m o > r* > p- Si Q X a X snt gX a m W (A r- r* X CD > (A m m m > 0 w > < < &r i -3<3 < 03 H O P 5m 30 a m 3 5S (A m H s I s (A 1 S3 m P* 32 -4 m S ro mm m m 3 T3 30 3i a a a m 3 2E m M HW > >> H > H > z =? w r r- r r- r* 0) ft* ft* ft* o T! 1 s CD (A cc 03 cm m a T3 T3 a a X a *0*0 *0 a a 33 c RR r Rm a m s m(A mtA $ mtA m 3 8 wu . oi oi MflS ON' M9> $ KS W W 04 r* r> ro o oo o qa o X c. o 'm a ft HH N m bt O ro > S3 3 ro O S3 3 .* srr>>> rv oi *0 |\ S3 M CD X s mn 01 M o o 24 4> 0> O oi HI so -A s> 'O n ro o* *s 0> M M *O' O' o* O' 01 s 0*l r* 01 ro M OI w 01 01 'O O1 ' <4#> C* H* o **sl ro a * W 5: rn oi in 'O n O 0 S3 KOor' O' O' $ O' 01 Nl OI 01 VI 01 Nl HI O' M O' 3 G r 01 ro H OI ro M W 01 S3 O' 4* 1 4> s| ro n w do a Si I* 00>1 QS8LW?090dna _9S8/^qsodna O' X I U CJ D-6148 342 H r Hi <a. * < >0 CJ O ca N fr :S sf* N J3 O' ro 10 ro H H in CO r^ tO CO CJ N o O O' H o H iH H *n r-i CO IO ro H ro >0 O to N sO in sj in 0 > C ro o O CJ CO H rH H M -# o HH CJ CO ro s o u to IsCO O' oz *58 *z * Ul *a o- o' Ift 1ft n* n . >- u >- H I a Hr O o U iH JH O < XH S OH H- tSk 3 gO 3< W I- CJ <o UJ JH X <H co x < 2z X HO U CO H UX gg X5 XH U (0 t z 1 ui H UJ rl > H z o5 Se o CO o X o< CO n- a ro UJ M r- M ua x UJ o t-- -> . 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H Ul u IH > -1 < z D. iIt IU h Q Q. mi mi mi mi iU IU XX aJ aaJ IU X jX w Ul o X cr CJ rv 10 u H rUJ a IH t" UJ < < uu t-J M zz < o H z u u o *raSS?S TERATOLOGY OVERHEAD zs8Zfr*osodna 8S8z^osodna TERATOLOSY OVERHEAD 0o n o n <n or* r" (-- 1- m m Hi M M M z SSI Z z z Z m n IH H M -I rn r*O n n o M rn> > > > o r* r* 7~ r~ 3 *3 X X XX o > > > > 1> wz 8 xOM m 2 22 3 2 m > -* >-l >-i > H > -i r m X mm C o > H m rn m m rn 3 X X XX X X m r* r- H n 3 w M Hi M Hi z 77 n nn ci nt =4 > r* >> r* r* > r* > r* -4 01 XXXX o 05 s> > > > X X _"11 g-< o m m m> > <o asQ 1" r- rn X 0 1 5 m 03 XX < c c; H Hrn H H Cl m rn H x O z R* fi* c fl* O XX m z C c: c e c m H X XX X X X > p* X p- Xr- Xr X X r* X rn H H Hi w H Z XX s s ss sr* r* X mmm> W 01 w 0 X> m rn m m m m g g gg> < < > r* >z P* m o> > r* H X os 0) 0) X H m m rn m 01 3 Cl X H < Cl M ci -< H or o> oi or oi oi n r r c- o c*> o oo O oo 8 u or or 01 01 01 or oi r> r> oo oo or O C X X 2 * -r S ox cn o g: X m< z* -i - o Zw >X CX rj o X l. om Xo Hi -t xM m a mi m r*> ci >O ro o c z -4 a m 3*-* 5H1 J> 3 O i X -t 2 0) o HX CX aa Mz mCl mo >o z 3--t WX r> w hn tsj 3 a x 5 a x -< 01 or H Oi a* o* or 4* o o Sl M 0* O W mJ -si H* or or o "I ! ol 5* n oo X m3 01 0J 342 D-6148 N H MM M 4S or 01 4>* c* or w CN 0> OI 4o- -O Oi 01 > o & or 1 m 5: PROJECT 372929 AUTHORIZED AHOUNT 1414922 CHRONIC INHALATION TOXICITY STUDIES ON T I0 2 AND TIC14-CD&P 6S8ZfrW)sodna 7025 000900000595 100010 96- 7589- 9,541- 1,124,512- o98ifrt-osodna 3 % 1XXI g orM~ 5 >P" T>J 3 Hrzras g C < n HfO S 9r- . 2ra T>J >Tj 3 r>- or>*s rmrr<a- H rm<-- WH n E gn>p>o 3 Szrom<>oaB m2OS H3o 3X zmon o>s -< a 0 1 s z i N| f Nl ra s wI win <MM Oz 3 S3 n mS ra m ram cs <0os os (ft (A m Srai wSt ra w *o M ra Ilf S5 3 nSB rSaB rSaB ' HH 3 rSaB g ra wss ra rr3a* 5 SraB g *> r* i-- H* ** gg fi* OS > fi* u (A O Ir- T3 MrTf(a0J oeras groas Mroas ra 5 ra S Of Vl fci 8!S SmB oras s s a s * 5 1 i 2 S ii s S3! o z o w r> ra ~S c 3 2 R 8"* *0ft* |.98ZfrK)S0dna g I iI 9 5 ki i k i 58e I 01 m r s w I 3 8 3 0) % 3m0 1 r- -C m I 8 f- l-- t>n i s g a < H 2 3 8 M 1 i. m 2 g 2 3 8 W $ A > r 3 H 8 =5 8 m U co m 0 1 3 s s H ron H n co m so < o 5 40 n 3 S 8 5 i <o 3 B 0 5 Si r 3 mr* H 3 B 8 5 S i- 3 m wH 3 8 5 1 sm;xmc g g > m (0 3 bm(0t 3 P > m (0 8 0 1 Xm 6 I 3 2 g F> -< rmXm* 40 oTt 3 m SJ NO fot g ? ions 2 *0 0 (X I I 04 0u1 0(X1 CM 0MM1 rws H* s vst 801 0IwX1 tx o 4> o *4 ft ^ Oos' R H IX 3 3 NO I NfS IX M 04 *o OS ft (X OP)' 4> OS Oe ft M s ft N *0o 01 8 M fet w o< w ft 01 s x 01 ft g w3 OS in oM OS is s O ft 0> ft M a jf3it*. o* 0s 1O5s 01 wft S 83 01 H <w0 I s VI is b* 01 Nj g ix O ft o o ft X3 05 H V 3 H ft M 01 01 a IX 8 ft ** ft H e w ft 01 * a ft 4S C H* ft h* ft IX N| ft *o a o 1 g o o a 0! O' s a #> b* 2 ft a 602 * * X3* ft Uf 9* e 2 S: s H 0) VI i m ft IX 04 z98Zfrfrosodna S98ZfrK)90dna t^szi^ogodna a s t? IM U rt MO Ip z 8" H CM Ul 35 3 gi gs U to H Ul s gg U (0 I *0 w io K> *0 to (0 s10 <0 N. k j |s <r CM N Ki i0 <> CM M MD M> CM *0 {5 ro 10 8 oo oo CM CM ro ro 10 10 K> fO W 10 K> CO a & S ^gS S K 8 8 9 9 3 . -1 J >1 -J Z <0 < < < < 111 1U WH OS OS WM OS OS H OS e y Ul \T Ul 1= Ul Ul HH Ul K 3 < s g OF Ul U (0 (0 Ul to a: < 5 Si (9 (0 ZH M> < H (0 Ha 1 ah- aui 1U H s 5 CO u hi > H H _J Ul in > Ul > Ul CO Ul 3X OS J J .j X u 9 Ul X OS Ul % 8 SS P OS X U>l. Uui OH <<<< a. D> a. CL > > <~i -1 -i J s e <<< (A u O ohi o o o ui 3 3 3 5 5z hi 6_l 3 W -J w -J eUxi Uttl U u* a u a J- H < S98Z*K)S0dna 998Zfr*osodna o 33 AS M ID M W co * ID * J-- 1 1W Ui a. * < to CO o nO o* 10 * o CM r^. CM je O' <? H H in CO N> CM CO A I-* K> O' rH *0 K> <0 M N NO CO s 10 in 8 ?n w o o CM o fH O' 0 8 o CO in o CM M3 H N CM HHH CM CM 53CM sO Ktf>t JinO us 10 n > N. nO CM IS io o R(0 % h Kin> JO W r* COt CM CO* Kl sh 9 H sO s*in6 r-4 H CO NO M3 AA HNH fO tinn miinn riinno O co to o CO o- H 10 O' C Scoi in CM oCM* o* CM O' 5 IU 8m iH Oo' CO e <0 oo o CM oo o hN N IO CO CO CM tn in in in fO w to JO oe o K s$ in to co (0 (0 UI m MH II. a CL XL i S ro <0 E u a s .j < J < J < z ui IH H M oc 06 06 a ui 111 UJ > fe fe 5 s :c til o g M UJ (0 ZW w> SS fe a s CD > a ID 5 <> < &< ID UI (0 (0 X 06 J X 9 3 35ID -i o UJ gs H l gg > .4 IU IO e fi a 898/>K>90dna msw tmmsmesw 7025 000900000595 100010 242- 6947- 14*126- 1*070*972' oz8zw)sodna tO *On' 0-6148 84 6 180 IU e to o < a. *h < to O N :g * CO i O' to to to UJ fH m 03 co CM CM N to m? < r-# sO H H o IA 0 to to H to o IA CM *c * IA to o o o o to A sr O in *o CM <0 <o r- "i **H O' CM CM o ca H tf) O O _J 3x B (Q 2 1 tu a CL S O >- u V1 X m <r p U f-i h- M U < Xw X OH oH CO *c .1 2O g< H -J -1 t<- CM O LU -1 W Xto <H X < zz X M5 c j co H IU 2W . oa X3 XH U CO I LU a CM O' id- UJ > X u O' ca O' o s: CM p-. o to IU N1 1" M uX UJ O X o 1-- X3 CL < IU H < to CM a ca <0 o i- <F to o u 1 co *o O' to to IO iH rt IA <0 rs. IA CM CM is. ro *o O (H o rH H m cO co o < ,IH to sZ z*- IU X * X 3 u tu H < a co g X o *s X X 3 U K X o a z to IA s CMCJ to-to IA W to to o o lA to IA w IA oo oo a - rs CM M IA IA to to ft <r <o O' to IU CO CO m UJ Ul z Ul H--1 H _J QL X X X X X CL CL a. a. XaL Ul 3 3 3 3 3 CO CO in co U) & O * 8 (A -J H < < <t < Z H H MM UJ X X DC X UJ UJ IU UJ IU h H- ml Hi < Z ' << c H >* - 3 IU -4 *s ml ml o X X ml mi u UJ pB X IU 5 CO to X X <> IU Xo o pp X e g < < < X a. X >- eg _J _i _J a O' u o <c < < ml ca H A* to u o uo H JH H K zzz< w --J a M ml X tu uo oH TERATOLOGY TECH SALARY ZLZLWQSodna GZ8Zfrfrosodna w.8z*K>sodna D-6148 CR&D ACCOUNTING 149 174 9 540 8 240 <o0* CM e s? 3 sIu tu 5 J0 CM a CM N. * <1- 1 to to * >0 * O' pH CM JO JO U) <0 CM N > O' ro r* JO m5 o a <0 vO M j o M3 K) O' M3 CM <>o 10 OH' Mh CO H 'O pH 1 nH CM sO' P" If) If) N CM to U) M3 JO 1U :S k i O CM le t )- 't S E1 s O' TO pH lf> O' CM CM jo *o m eO' tMo3 Mi* H O CM JO 1(00 CM <> H H * H CM If) If) mg O' o * sO' o 'ST CM CM aO' > sQ! o> < CM UJ O' If) CM UJ N Of to Jh <o p: w i5 1 oo CM CM JO M If) If) JO 10 o o CM JO If) 10 80 (0 (0 0) CO UbJ IU UJ W ttl a 3 33 3 CL a. a CL. CL CL g i x l a. ss o. <0 9 *0 ml -J u -4 < < << < M H MH H rc a X K DC IU Ul IU IU IU i- i- J- J- ;g tau (0 IuU > a a CO o CM CM 8 1If0) >* 10 Q 2,, m 3 9(0 10 IU IU I X u X > IU > 3 <0 es Xu IU O O Q DX O 111 <x O >o U CM g EEI X s g uI s z 3 - I i co tu s p Of K 5 E K> U) 3 in !U > Hi Q 5 < Hi W UJ B <u pP ui n o ZO 3c k CL - UJ *< a .e Ml tu t 8 P uz <O 32 * fe * ui os :s o i N o tO a js K o 0 < Sf ri O 0 8 1 Of au tu to o a a a X 8 Fi s sto to Kl to CO to M to d to CM <fs0 N 10 s O' o * w 0 sr 10 O to CM MO o CM % s O' d* f-l o oO o l-l 0* o H H H CO CM M CN 3 *< Q to CM jCsM 0* O * h S- N * CN to HJ to <0 O O *0 H CM Ut CM <0 IS h* Mi <0 o Ml Sf cu -<r H M O' 1 rtCM * to H H * H H CM 8 U ui 3E 3| K ls id <o Sl- N <o 2 LU Of :3 Oo <0 <r IA * Ul 1 X *a *2 XXL Of 3 U u I LJ (zJ UJ Of UI oo oo CM CM Kt MI lit IA torn o o CM Ml tit to CO o* <0 W O' <o to <0 u P (0 Hi >>- H Of H mJ < Ui to to to Ui ui 33 (ft tO Ui UI 10 UI <Of CL UJ 2a tu Obi X <Q UJ >- sdK> c > UJ < > UJ J -1 < < (0 g Ul g w ft & "33 1 *7 B 5o to to t- to E UJ s H M > 5 CM 5 X >- p X H- > Ui <8 8 -l -J -1 3< <t <t M H HW 3UJ a Of a a X LU UJ ui UJ II i sUi h H 1 0) tu (J M > X tu z M < X J < X H z H CO h a Ui o o w M Q3 Of UJ UI O' 5 HI Q CL X Q M 1 0 W O' CM is Mi O* x P o M h Ui Z UI X g o H h UI Z Ul < 0. -i u M z w < a -i u H Z M U < a < a w z M -J < a ID o Of pu j to < CQ O is o u u u u u II >~ 9 tto ,e> to p tu i- II DUP050447876 TO 8 ap $ o* O' a a. 0 H ak N *<or too TO <o io iono a CJ g O' 5 Jfr *0 1A O rt >0 O O' iso0 IO TO I M <0 S <o 3 <M s *< ;a O * h o CO 1rv0 IO co 3r 10 10 rH |V <0 TO TO CO rH O TO O to O' sD O e tv CM to * CM 10 H TO o co *o O' o m O' c *m vc?o m CM CO St *-l O' rH fv to <0 CvJ CJ I sa fe r' >OS H Sf O OH ss sa gg <t o -J -* 2Z wo o co H Ul ZH SI U 0) P 1 til O S I a s 1U0l Ul > oX O' o < UJ CM O' 5 CD CJ w 1^ Q Of TO Ul N KH < O Df Of IU O -> o X h Ul a 3 oa < ift A! N ro* O' e r- r- TO O in o 10 ** 1" *< *a co O' o g*- co s0 N CO o* TO O' CU :g > tt : O Ul 0 1 1ro0 co io a rino to 10 t o TO Ul y OUfl Ul a 10 rH O' rH O w o iH H> CJ stf- H M o i- CJ io w s 1to0 K) 8 I R H sO r RR O' CJ O' 3 8<0 z Ul s 3CL X UJ u. o CO sH z 8 g gUl z 5Ul 1J s sUl 3 Ul X X Ul g >CD o _J pu w X o h UJ -4 -1 < CO >CD o u M X o H Ul J -J < (0 I >tD O -J o u H X o H > c 0) 5 Ul H t >CD o J O u H X o K <3 (0 Ul u M > X HI CO _! < o H Z X o UJ H .J < (0 X U Ul i. UaJ (0 > 8s Uh*l a <c Ul X O' So C>D- o 0H >Ul i >CD- o O hi 0Xto 1 > 3 -1 8 S 2 X u CD 3 8 R >o :> z -j 3 a tL 10 > Ut > 1 >z o Ul CL CO 1<0 5HUl M mJ < huUCCOLtl XNo ahH-i UOJf 8 C3C S _<3 >Z C<CDL oH OM (hcoOo u UUCzOll Ul -J H<OJ- TOO1O0-J CD P Cz<uXIO-. toooaOoooooOo'' tCo|VoM DUP050447877 CENTRAL RESEARCH & DEVELOPMENT DEPARTMENT HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE DATE July 20, 1982 TOS K. D. DASTUR CHEMICALS & PIGMENTS DEPARTMENT REVISED B-6314 C2 ndi PROJECT MR- 2929 PART II TITLE: CHRONIC INHALATION TOXICITY STUDIES ON Ti02 and TiCl4 SLM UU mm Authority is requested to undertake the study identified above and described as follows: Two mathematical errors occurred in preparing the original MR-2929 budget (1. miscalculation of the lab assistant category under the "study" portion of the project accounting for $68,000, and 2. incorrect application of the 10% per year cost increase rate, accounting for $15,810). Both errors resulted in a cost underestimate of $83,810. ' . In addition, final, study charges are anticipated to overrun the corrected study budget by approximately 9.4Z ($126,190). This overrun is due principally to a greater than expected increase in inflation rate. The preceding items will account for a $210,000 overrun on the amount originally authorized. This Part II requests C&P to authorize funds in the amount of $159,538 which represents 10% of the original authorization ($125,538) plus one-half of mathematical error #1 ($34,000). No charges beyond those specified in this Part II will be charged to C&P. . Amount requested$ 159*22 Previously authorized - $1.255.384________ Expended through Apr *82 $ 1,263,217 (date) General Ledger & Sub-Account to be charged Forecast month and year: Experiment to start 6/79 Experiment to end .6/81 Final report to issue 2/83 (TiO,) 11/82 (TiCl4) Request for study made by discussion between J.R.Gibson and S.N.Bovd.Jr.. 7/20/82 CLASSIFIED: R&D OTHER (check appropriate classification) If this request meets with your approval, please enter the GENERAL LEDGER & SUB-ACCOUNT TO BE CHARGED and the CLASSIFICATION, have the original authorized and return to HASKELL LABORATORY, CONTROL SECTION. The additional copies may be retained for your information and distribution. _' Proposed by_____ J ^ *` Approved by H. J. Trochimowicz HJT/cgs - 7/20/82 Authorized (date) DUP050447878 N 30812.06 CUUWECTED* APPROXIMATE COST FOR TWO-YEAR INHALATION TOXICITY STUDIES ON YiO? AND TiCl4 Description Total Based On 1979 Costs** 1978 Distribution 1979 1980 1981 1982 itUMALS ` initial Costs - 1420 rats x $3.00/rat Maintenance - 1400 rats x $0.22/day x 730 days (total excludes rats sacrificed during study) $ 4,260 224,840 NALYTICAL d e v e l o p me n t a n d c o n t in u a n c e One Toxicologist/study Development - 2 Toxicologists x 240 hrs x $49/hr Continuance - 2 Toxicologists x 3 hrs/wk x 104 wks x $49/hr 23,520 30,576 $ $ 4,260 $ $ $ 4,704 56,210 112,420 9,408 7,644 9,408 15,288 56,210 7,644 TUDY One Technician/study - 2 x 40 hrs/wk x 104 wks x 822/hr Three Lab Assistants x 40 hrs/ wk x 104 wks x $22/hr 183,040 274,560 45,760 68,640 91,520 137,280 45,760 68,640 Ul'ERVISION Coordinator - 2 hrs/wk x 104 wks x 2 studies x $49/hr study Director - 2 hrs/wk x 104 wks x 2 studies x $73/hr 20,384 30,368 5,096 7,592 10,192 15,184 5,096 7,592 LINIGAL PATHOLOGY $18,973/study x 2 studies ATHOLGCY 600 rats/study x 2 studies x $2i2/rat Shared control - 200 rats x $212/rat Special stain for Ti02 rat tissue600 rats x $30/rat ivmsTics $5000/scudy x 2 studies 37,950 254,400 J 42,400 1 l 18,000 vI 10,000 15,180 15,180 7,590 31,480 31,480 94,440 157,400 10,000 l sc el l aneo us Disposable clothing apd Reports 20.000 J liTOTAL U.0WANCE FOR INCREASING COSTS 3TALS $1,174,298 $4,704 $4,704 APPROXIMATE COST FOR 24 MONTH STUDY $lj 339.194 3.330 $254,600 xl.O $254,600 3.330 $441,282 xl.10 $485,410 3.340 $296,312 xl.21 $358,538 10.000 $177,400 xl.33 $235,942 ' Corrections consist of: . L. Cost for Lab Assistant category under "Study" heading 2. Cumulative allowance for increasing cost --nils COLUMN WAS MISLABELLED "1978" ON ORIGINAL COST ESTIMATE '.W.Schneider,Jr./rad uly a, 1982 DUP050447879 /. t i t REVISED APPROXIMATE COST FOR TWO-YEAR INHALATION TOXICITY STUDIES OS TIP; and TiClt Aniauls Initial Cost* Maintenance 1120 rats x 83.00/raC 1100 rats x 0.22/Jay x 7JO days (Total excludes rata sacrificed during study) Total BaacU on 197B Cassis $ 4,260 22'.,-0 iv;s s ________H12 1979 1980 S 4,260 $ 1931 s 1982 s 56.210 112,420 36,210 Analytical Development and Continuance technical One Toxieelogise/study . Development - 2 Toxicologist x 210 hrs. x $49/hr 23,520 ` 4,704 9.408 9,408 Continuance - 2 Toxicologist x 3 hrs/wit x 101 wits x S49/hr t\ Technician/Lab Assistant One Techniciaa/Scudy - 2 x 40 hr/wk x 104 wks x $22/hr Three Lab Asalstancs x 40 hrs/wk x 104 wks x $22/hr JO.SIh 183,040 Id i- 205,920 7,644 15,288 45,760 91,520 45,760 51.480 102,960 51,430 Supervision Coordinator - 2 hrs/wk x 104 wks x 2 studies X S49/tar 20,384 5,096 10,192 5,095 Study Director - 2 hrs/wk x 104 wks x 2 studies x $73/hr . 30,368 7,593 15,134 7.592 Clinical Pathology . $18,975/study x 2 studies . 37,950 15,180 15,180 7,590 Pathology 600 rats/study x 2 studies x $212/tat Shared control - 200 rats x $212/rat Special Stain (or TiOj rat tissue 6AQ rets x S20/rat Statistics S50Q0/scudy x 2 studies Miscellaneous Disposable Clothing and Deports ' ' Allowance for increasing costs . ................ TOTAL . . . (.............................................. 254,400 42,400 18,000 10,000 20,000 1.105.6S8 $1,105,653 o 09 H# f-9 31,480 94,110 157,100 H.-CO 4,704 $ 4,704 3,330 3.330 237.440 406.962 x 1.10 $237,140 Si<T,653 3,340 279.152 x !.20 20.200 177.ICO x !..'0 APPROXIMATE COST FOR 24 MONTH STC3Y $1.133.3Si Prepared 4th Qtr. 1978 DUP050447880 .* 4, CENTRAL RESEARCH & DEVELOPMENT DEPARTMENT HASKELL LABORATORY FOR TOXICOLOGY AND INDUSTRIAL MEDICINE DATE July 14. 1982 TO: K. D. DASTUR______________________________ CHEMICALS & PIGMENTS DEPARTMENT B-6314 ' REVISED PROJECT MR- 2929 PART II TITLE: CHRONIC INHALATION TOXICITY STUDIES ON TiOz anti TiCI4 SLM Uo JNFO Authority is requested to undertake the study identified above and described as follows: Two mathematical errors during preparation of tlie original MR-2929 budget (1. miscalculation of the lab assistant category under the "study" portion of the project, and 2. incorrect application of the .10% per year cost increase rate) resulted in an $83,810 underestimate of the true projected study costs. In addition, final study charges are anticipated to overrun the corrected study budget by approximately 9.4% ($126,190). Tills overrun is due principally to a greater than expected increase in inflation rate. This Part requests authorization of funds to cover the existing and estimated charges from both of the above cost sources. Amount requested$ 210.000 Previously authorized $ 1,255,384 Expended through Apr *82 $ 1,263,217 (date) General Ledger & Sub-Account to be charged Forecast month and year: Experiment to start ______________ Experiment to end 6/81 Final report to issue 2/82 (TiOg): li/83(TiCl4) Request for study made by __________ CLASSIFIED: R&D OTHER (check appropriate classification) If this request meets with your approval, please enter the GENERAL LEDGER 6 SUB-ACCOUNT TO BE CHARGED and the CLASSIFICATION, have the original authorized and return to HASKELL LABORATORY, CONTROL SECTION. The additional copies may be retained for your^^lnformatiq^ and^UThtvrbution. Proposed c Approved b; PWS/cgs - 7/14V82 Authorized (date) DUP050447881 CORRECTED* APPROXIMATE COST FOK TWO-YEAR INHALATION TOXICITY STUDIES ON TiOo AMD TiCl& Description Total Bused On 1979 Costs** 1978 Distribution 1979 1980 1981 1982 NIMALS initial Costs - 1420 rats x $3.00/rat Maintenance - 1400 rats x $0.22/day x 730 days (total excludes rats sacrificed during study) $ 4,260 224,840 $ 4,260 $ 56,210 112,420 56,210 NALYTICAL DEVELOPMENT AND CONTINUANCE One Toxicologist/study Development - 2 Toxicologists x 240 hrs x $49/hr Continuance - 2 Toxicologists x 3 lirs/wk x 104 wks x $49/hr 23,520 30,576 4,704 9,408 7,644 9,408 15,288 7,644 TUDY One Technician/study - 2 x 40 hrs/wk x 104 wks x $22/hr Three Lab Assistants x 40 hrs/ wk x 104 wks x $22/hr 183,040 274,560 45,760 68,640 91,520 137,280 45,760 68,640 UPEKVISI0N Coordinator - 2 hrs/wk x 104 wks x 2 studies x $49/hr Study Director - 2 hrs/wk x 104 wks x 2 studies x $73/hr 20,384 30,368 5,096 7,592 10,192 15,184 5,096 7,592 LINICAL PATHOLOGY $18,975/study x 2 studies ATH0L0GY 600 rats/study x 2 studies x $212/rat Shared control - 200 rats x $212/rat Special stain for Ti02 rat tissue 600 rats x $30/rat 37,950 254,400 ^ 1 42,400 18,000 v 15,180 15,180 7,590 31,480 31,480 94,440 157,400 I'AT'ISTICS $5000/study x 2 studies 10,000 10,000 LHCELLANK0US Disposable clothing apd Reports 20.000 JBT0TAL LL0WANCE FOR INCREASING COSTS QTALS $1,174,298 $4,704 $4,704 APPROXIMATE COST FOR 24 MONTH STUDY - $1,339.194 3.330 $254,600 xl.O $254,600 3.330 $441,282 xl.10 $485,410 3.340 $296,312 xl.21 $358,538 10.000 $177,400 xl.33 $235,942 -`Corrections consist of: . 1. Cost for Lab Assistant category under "Study" heading 2. Cumulative allowance for increasing cost *TUIS COLUMN WAS MISLABELLED "1978" ON ORIGINAL COST ESTIMATE '.W.Schneider,Jr./md uly 8, 1982 DUP050447882 /f A / t i. i / REVISED APPROXIMATE COST FOR TWO-YEAR 1SHALATIOH TOXICITY STUDIES OS TIP;, and TiCl4 Initial Costs Maintenance 1420 rats x $3.00/rat 1400 rats x 0.22/day x 730 days (Total excludes rats sacrificed during study) Total Bnsod on 1978 Costs $ 4,260 224,8-0 197S S Analytical Development and Continuance technical One Toxieologlst/study Development - 2 Toxicologist x 240 hrs. x $49/hr 23,520 4,704 ..x'Ji Continuance - 2 Toxicologist x 3 hrs/wk x 104 wks X S49/hr i Technician/Lab Assistant One Technician/Study - 2 x 40 hr/vk x 104 uks x 522/hr Three Lab Assistants x 40 hrs/vk x 104 vks' x $22/hr 30,576 183,040 X.y *** "*! * 205,520 ' Supervision Coordinator - 2 hrs/wk x 104 vks x 2 studies x 549/hr 20,384 Study Director - 2 hrs/wk x 104 uks x 2 studies x S73/br 30,368 Clinical Pathology , 518,975/study x 2 studies . 37,950 Distribution 1979 1980 1981 S 4,260 $ S 1532 S 56,210 112,420 56,210 9,408 9,408 7,644 15,288 7 45,760 91,520 45,760 51,480 102,560 51,480 5,096 10,192 7,592 15,184 5,096 7,592 15,180 15,180 7,590 Pathology 600 rats/study x 2 studies x 5212/rat Shared control - 200 rats x 5212/rac Special Stain for Ti0;j rat tissue 600 rats x S30/rat Statistics S5000/study x 2 studies 254,400 42,400 18,000 10,000 Miscellaneous . Disposable Clothing and Reports 20,000 Subtotal ....................................................................... 1.105,658 Allowance for increasing costs ...... TOTAL . . . ...................................................... ' 51,103,653 31,480 31,480 94,440 157,400 Iv, ,r.O 4.70* 5 4,704 3,330 3,330 3,340 237,440 406,962 x 1.10 279,152 x 3.20 5237,440 3447,653 S33**,^S2 10,000 177.4C0 x \. 20 i-,V)ouO APPROXIMATE COST FOR 24 MONTH STL'DY $1,255, Prepared 4th Qtr. 1978 DUP050447883 VYt v*> A VJ nW*Al * CMM:.^,:' fcjWlfc*. l|&)trtW 0'?S }j dw?tv<l WM^vf : I'^rj!-; |>W^ \o% 4/v.j..:-ft ' "i'>( > 10 t *fn,T*'j WyV m-'fiW ......... r>rMa fXvH^-.- sW' awjHUJP * *&a o<3a,-o ijuV<V- $ ' > Wi _ /, rtVV./v/ _ tlu i-5 |ji,i fUC'ALkj:^ ';* v > -; 5A'J<;~ !*$ V)i';!-Avv\ VQfs i\ &J> 'jjnu.iid iMxiuid.! ' DUP050447884 N 30812.07 CORRECTED* APPROXIMATE COST FOR TWO-YEAR INHALATION TOXICITY STUDIES ON TiO? AND TiCl 4 Description ANIMALS Initial Costs - 1420 rats x $3.00/rat Maintenance - 1400 rats x $0.22/day x 730 days (total excludes rats sacrificed during study) Total Based On 1979 Costs** 1978 Distribution 1979 1980 1981 1982 $ 4,260 224,840 $ $ 4,260 $ $ $ 56,210 112,420 56,210 ANALYTICAL DEVELOPMENT AND CONTINUANCE One Toxicologist/study Development - 2 Toxicologists x 240 hrs x $4.9/hr Continuance - 2 Toxicologists x 3 hrs/wk x 104 wks x $49/hr 23,520 30,576 4,704 9,408 7,644 9,408 15,288 7,644 STUDY One Technician/study - 2 x 40 hrs/wk x 104 wks x $22/hr Three Lab Assistants x 40 hrs/ wk x 104 wks x $22/hr SUPERVISION Coordinator - 2 hrs/wk x 104 wks x 2 studies x $49/hr Study Director - 2 hrs/wk x 104 wks x 2 studies x $73/hr CLINICAL PATHOLOGY $18,97.5/study x 2 studies PATHOLOGY 600 rats/study x 2 studies x $212/rat Shared control - 200 rats x $212/rat Special stain for Ti02 rat tissue 600 rats x $30/rat 183,040 274,560 20,384 30,368 37,950 254,400 42,400 18,000 45,760 68,640 91,520 137,280 45,760 68,640 5,096 7,592 10,192 15,184 5,096 7,592 15,180 15,180 7,590 31,480 31,480 94,440 157,400 STATISTICS $5000/study x 2 studies 10,000 10,000 MISCELLANEOUS Disposable clothing and Reports 20,000 SUBTOTAL ALLOWANCE FOR INCREASING COSTS TOTALS $1,174,298 $4,704 $4,704 APPROXIMATE COST POR 24 MONTH STUDY = $1, 339,194 3,330 $254,600 xl.O $254,600 3,330 $441,282 xl.10 $485,410 3,340 $296,312 xl.21 $358,538 10,000 $177,400 xl.33 $235,942 Corrections consist of: 1. Cost for Lab Assistant category under "Study" heading 2. Cumulative allowance for increasing cost **THIS COLUMN WAS MISLABELLED "1978" ON ORIGINAL COST ESTIMATE P.W.Schneider,Jr./md DUP050447885 N 30812.08 .........-........ *. - ...... -............- --;...... ....- 1.................................. ..- ^ 4 JP ............ QgggeTEb kMaBMH&XL COST $MiThl{*iA\im ta<i.c(T^| stuAu*. 010 '\m. AaaXicSu 'i&lUtU. rn< K\ Te.W.&it tr ^ Mm i<m CVtlU 1180 ^ f?e i I1BZ . ........................................... v................................. ....TMi- tUto vuk i..... .. i.............. .. t :............... 4.............. .....#............ 4............... quo .................. .... ................................................................ ...... 2PhtMo ... . ....... ............................ ........ftp bA tK&jjjM tth iuA '.K'.faj') ..................... ..-......... ....... . SMto. .. . . . o<Aft. Totitofeo^fs t- /. ..6^iT1.MWrt'iCf,................ . ,, ....................... .......^/.................. . ......... tftak^iwwct.r...... 3o$k. . .....................................tdq nUv.1' ` ....fit*#... ...' ... rf/MoB ......im~...... ..\*t{t 9 ?>. ................... ................. -..... ...... 7Mi ... .......... ..... tti'..k'..kiv {fjA kj s WJ.j - %. % io Ww>L Y.MH v>k. I Sit Wti. ft UVAsfakhii t MtM&.lv&'f.iMuteM.... ... . . ..... yi/.tbQ. . %%* . j&M. ...........- . -.................. .......bS/itfo .... l$ltt&o... ...... b8,W_q..... .................. - 5a|fcfcuvs.tow % : * ! .... ;^.?VCUUA.t/y:. .it ip^jJ/A-y 2<i?uyiuy v/ ^.&rt.tCLk.r. J:}^jiA.X..!3l>k ...... .... . . Wti<iZr ......$1%. ................. .. . 1M . a 9H ....... Wii-... .................. ctua/M ............. .................... ______l_&( !l,1S /.ikU'-' Z-, ifviU&f ............ ,............... .....^............ . . ...... ..bso vjk jS. WJLj V 2 S ktMdj Y 2n/v.< \ .......... S&isfrd 'talHtrir Zoa.yxji ftjz-jy&l...... ......... ..... ................. l tun TtO^vaf fj*iw..-. ....... ...................&&& va. W. . -VWE^q c .5................................... # .............................. ........... ^csooJfsfyv^ny.i..sWktf j....................... .. tMi^e u a *&>u a ^.............. ___ __ % n^dfj MMi. .wj Jcifc. Stv&TD-mt. *<?.& .MB. -TQl^WST .......... .................. ........... ......... ........ |?i.-U..... ..... !\m.. ........ ii^.vi .. ................... Asry,a?3 / ..... T5j4$e........ .31,^60 .....tyW.. .... isttfm.... ........................ ..Jfifft??.... -................ ..-.............. .................. ..... f0fO ......... ............. J&SSSL... ^im.Z ...... i,no" ------ --.. , 141*53 ....... I'-rH.. ^M}>-... . M.%m.. ....^%3t%..... ....mm...... ..... * ha/ )tUi6 sf I.^-l Vl/<3? .......>fr?H ' tSlfj .. */.6,Mto . mA M,^..c.. ...fijl r^i,.i.m... ':. ................. % .............. \t...,...._...... ............. ............... . . .......... 1. l&i i ju*:.,,.V.4... D?:?, -fi' AVv<...d^^^T(|.WjW^fe>/_. _____*- 41-VtiWiilUii. ikkt'AWLt.If-i..'r AGrttsiiSM. &r\r............ . ! .. T]M * 4' '<--5/yS /Vt/Ji.. ftt.&.&.tzPri' ?. ....... .... ........ -.. -................ ........... . -......... ............... ...... DUP050447886 CENTRAL RESEARCH & DEVELOPMENT DEPARTMENT HASKELL LABORATORY FOR TOXICOLOGY AMD INDUSTRIAL MEDICINE >9 'z-f DATE June 17, 1982 TO: K. D. PASTOR__________________________ CHEMICALS & PIGMENTS DEPARTMENT B-6314 PROJECT MR-2929 PART II TITLE: . CHRONIC INHALATION TOXICITY STUDIES ON Ti02 AND TiCl4 Li d In f o Authority is requested to undertake the study identified above and described as follows: The subject MR was prepared on the basis of an anticipated 10% per year cost inflation rate. The actual rate, however, has been higher and that for Research Assistant time, which accounts for the majority of Toxicology and Pathology Division charges, has been substantially higher (27% per year from 1979 through 1982). In addition, development in pathology procedures (extra tissue sections, special ' stains, new GLP requirements) which have resulted in respective increases of 66 and 25% of technician and pathologist time per animal have contributed to higher than anticipated charges from that division. The higher inflation rate makes up 60% of the overrun while new procedures in the Pathology Division accounts for 40% of the total. This Part is written to cover the overrun and additional charges expected to accrue for the above reasons during completion of the study. `t ` ' t<?7f *>3t, * 2^ Amount requested__________ $210.000 Previously authorized $1,255,384 Expended throughApr. *82 $1,263,217 (date) General Ledger & Sub-Account to be charged Forecast month and year: Experiment to start 6/79 Experiment to end _______ 6/81 Final report to issue 2/83(Ti02): 11/83(TiCli) Request for study made by __________ CLASSIFIED: R&D OTHER (check appropriate classification) If this request meets with your approval, please enter the GENERAL LEDGER & SUB--ACCOUNT TO BE CHARGED and the CLASSIFICATION, have the original authorized and return to HASKELL LABORATORY, CONTROL SECTION. The additional copies 'may be retained for your information and distribution. DUP050447887 N 30812.09 888Z*K)S0dna r 688Z1^V0S0dna ro >5$ w s o3 o>o 2 s 001 MI $ m a s S B s s> 3Of r<.; w m n. axnst 6 M O o 5 m > o c 3. 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Vi a 05 P0 a o 5: m (mAa H400 im H> O' 806z**090dna ACUTE STUDIES TECH SAURY n o <n -a> m on oc r* m MZz l o z 03 H4 O 3> z M (ft m m X fi X > -4 XX >> -i -i 3 > -1 <c5 55SO3 3 z> mns m u c za>(ft < 0>) I- r- *0 > H X (ft > r* Mo r* TJ > H X O < m -t -4 O X 1 --r ni o H O X q < m 73 X MV| ro o i i-* ro o o o 1 m o H n X > X 03 m 5 X o M < h-4 (ft W o z 5 XX oa 4-1 M << WM (ft (ft M HI oo zz O nr - H (ft --4 H Z rn 3 ni X > r* z > M Z H m z > z n < HI o rn (ft i O --4 X m X M X X m z -4 X m z -4 > f" m X w > r* a (ft c X X f" HI mm XX MM >> r~ r* tft (ft cc XX XX f rWH m X HI > 1-- ft (ft C X X rH4 o> x m m 33 at tn< X > r* > m < r* m < M X X m > o <ft > r> x ni > a 04 01 04 O o o 0) o X > 73 03 no XX >> XX 03 G) n X > z H m a m X H (ft m mm m m (ft (ft (ft (ft (ft *< M -< m mm (ft 0) (ft 04 04 (ft (ft to ro 04 04 04 (Jl (Jl (Jl 0o4 0o4 0o4 a oo o oo 0U4! 0014 00140014 04 04 04 04 w ro ro ro oO oO oo 90 nm 8 240 ^o9 OoM' O' 0 o 9M 04 r H O' M H* H CO M O' o>* o * M04 M O0044' e 0y4 O (0f4t fCt** 04 G0OO4' Og>' (ft oo g* to to (ft H* 04 4> *4 -oSgj x dS o m- o* S: X 3 zO KwB -x1 tr* m a oo (ft H * Mto to or a 3* m* o S: 00 *0 0'O o> zn ss o g> Of 0C4o to (0f4t r> H 0 O(ft' H* (fftt ou) f* HO nJ to r0o4 a >H 174 0-6148 no O X =| 70 H -X* z03 041> 04 1255384 CHRONIC INHALATION TOXICITY STUDIES ON T I02 AND TIC14-C04P PROJECT 372929 AUTHORIZED AMOUNT (ft 0O4 *4 606/m>sodna ut 04 WO' Mo No I I 3 x -OT C33 M Ol o>Hm -U ) ro H 04 0> Oe ui l\ o zH N 3 O 09 ZM m na H -4 a ro Ot H 04 o> 01 01 *4 M4 01 <> O' H or 04 ro f9 r* ot 04 01 M Ol 04 ra M 0 4> CD 4> 01 04 04 O' o 45 o o CD 4 H* o o O' 01 o o M CO M 04 O' O' 04 45 CO o PJ o a > O' oCO -C' O' *o 0 o 04 M ^ CoDi &O O n> ro f<\0 I*N4> o c* 70XJ m * H* 04 3 5 5 33 01 Ol 04 o 01 M o I ro 0>41 4) , -f -*> xo>. o >o r o & > -4 m 0) O 3 Hm(A ZmO OZ -w1 >rMzX- ro > H*OH*I s jrm0:--**) p- i-Mnm 1P4* HzHOmnHX4 soX>--o4 -< 8"* -a M4S CD 04 aa> -XDDD03E3 PRTR953 cueztt'osodna ITOXICOLOGY -SAL LEVEL 353020 -I a x sMOo > > o o O o sj sC H qqf -m1 -rn* z M z w zM Hz n r* n o 0 G-<S o<-<a 0> 0) > > > > 3 rH- r- r* r r" a X n *n X t o1 OS > s m m 0> w rn V) H m 0) > H X > > S > 5! Xm Hm o x w > n q < rn X rn o X 0) > r- OS > r* o < m X r- rom < X m > OS 3> r* < r* m < X m > VI 04 ro roa r- a r- j> r- M -< M XM -< H 01 VI 04 O' 4> 01 ot 04 VI ro rro Vl rroo H VrrooI o oOo w VIVI 4> ro03O H 0) Eto | H 33 > J> HH 55 H 2 > -f rn rn ro>3 r* ro rog <W n m 0) X w > r* m rn XX MM >> r* r- rn X M > m X H > 3rn Z 0) M i s* rofi* s o roHzm ro ro ro roo3mx Z > z o m -q4 X m X a rn OS c a *o rH rn 0) OS OS GC *a x XX ww ro rn OS OS os c X X M m OS OS c X X w m 0) rn X X rn Z0) ro a noMs nn aoo aoo w ot VI vi 0O4 0O4 O OO 04 04 Ol VI VI VI 0p4a 0p4 0p4a ao oo oo rn zmr Zo rn 8 Om xx * 3 = gl oS" 5m : H roOl roVI 4> ro Ch s| 0 O os os co Co roo JN si in in g iX o x K N n-I > r- rn o ]> o c z H Om < ro VV0404>>ii a m 5 X CX ac hm zw 0) o g-I X>z sc > HO Z ~i q ss mn 'f H s-* R* *11 1 X R1 >0OX 5 s -< 12 379 720 21,420 772 M >v0j VOI* oho* * CO o o si ro roc*o4 04 V04I H 'O VMI 0> V if: rso| 4ro* VI o >* -1 H O' j> in -V Sj H ro si 01 ro CO 0> VI CO 0> si VI VI ro W vroi vi Vi ro vi v ro 1- V yi H 4> si 'O vi H* *o i-j si 4> t-* >o 4N 09 4> o si O' O O' O' Ol O' 01 *o in o Ol O' 0> vrosii Ho'C* $vi ro VVII ro W40 ssii n c* Ink r S --i irooi Q> H pi c 5 om ro *oo 12,497 D-6148 XjO V01I D-6148 CRSD ACCOUNTING ii6iPvogodna O01l e! 2 r* xTJ CraO 4051 O o Osrol o 4> 04 4O5 45 43 43 45 05 0 ro rotfi *rn0 nH5> r* M z < -m< nX <> to < to 3m oH >r* M < 05 > 5 S3 *< cm < H m0o5 n w > r* w z < o <m70 X ro 3> o T>HJ X o0H1 OroG) -< 1 --i ro n 3 0) 3* r~ ">0 3 Q Ww opo <-<7 0>) r r* m < w >*-oi X o0wo5 rO <n -) r* rm < w M *t> >XH o w03 ro O G-4) Om< X 3 m > o -1 o X 7u0i < m0) n i ~i m o3 o> > P- H 3n ZHn> r* 0) Xr<o M n ro 0) </) ro n o X Hno o G1 -< m 2 r* m 3nz! 0) 5Tm55 Z0) OI 45 43 45 45 45 W 0 I* 3m) m7n0 m Z n nr Of r00o41 0o4 000bro441* o Of 01 K oo 04 0H00414* O Of 00M14 OO 0041 00o44 tst o c 3cX0 * 3o *X 01 ro u0i 01 in ro o01j HC s a 04 > Hm 01 Pv) 01 0f1 O01f (V> 0? Xm * 3: 00ro14 b45** O O CJJ M O ro Ol *s| *1 >1 01 H 01 S-n3 M 04 01 H* Of 04 Nj N o Of N H 1o <3 04 43 C> ro 01 45 fHt 05 01 04 O' o O' e O' Xj ro o O' O' 01 o o M CO 0> O * O' Q 0> > H 01 0l ro *4 45 04 O 45 o Ol 45 O 1 o cX g: *03 4O5 o- 04 4N 04 0O1' O' 5! 05 w S_ >. 3q XC 803 H ro ro roro ro roH O H* M O M O' M -S' V01 4> l- Vw o 4N vf * ro roO' e 0) 45* 05 O' 04 N 01 o -> 04 -4 01 CM 45 H 45 *4 4N 01 4) -P' O 01 H Ol o m J> TJ IC SOO 70 (H N 5 r*o4 o o >0 c 0011 S -w4 nX CoM ZSo3 mh 03 O OH zz *H 5 Horo r*>4- X > srn rr~" c. c 5 2 6) m 0o4 o Zl6LVP090df]Q o n o o s| o n r-- r* f- r* -O o n n 01 o oo H c c HI w M HI 1 z zz O "1 -1 Z z z z Ol 13 X X m m n M h i HI s| a c c c a O n O o 4V HI H --4 H ro to (A > > > > -O X ro ro m X H H r* r* [-- r* IV ro X X X H C cz & o 3> > > > VI z zz z z rn z z z z ro > > > > > r- Hi HI HI HI X --4 --1 -4 H -I H H rn ZZ Z3 >>>> < HI ro X rn ro XX rn X rn X rn m Xx z m r- i~ p- ro o HI HI HI H HI HI HI Z rn > > J> > > > H 2Z3Z > > j> > to r* P* 1" r~ r~ r* i-- to o M rn to CO > r- i-- ro < a M m to O < ni X X ro > X > e! H rn o z VI > x > -4 X tn > r* ro < x > M X CO > 1-- r~ ro < 13 > a < ro X X ro > 1 H4 IV -P* O O O 1 04 VI 04 O -i o X > X o m V) o HI < HI V) w 9 n X > aa MM << MM (0 V) HI M oa zz oo XX >> V) -H HI z rn z ro n X > z z o m M HI M HI zzzz --1 -H --H --1 ro ro ro ro 55 zzzz onoo ro ro ro m 1 o 3 rn X a m X 6* to c X X r* M m (0 Ro Ro to to CZ c XX XX r* r* HI HI rn ro to to i> to C X X 1-- M ro to r* to cz X X r* HI rn to ft* (O CO cc XX XX r- r" H M ro rn to to o -n ro X X m z to rn ro a r" ro ao X X X HI r- > r- H o o a <n n XW ro m rn 01 H -< w to to to ss aa ao aa 04 04 0041 0W4 04 04 OG o Oo ion rov voi iov JP* O* 4* O' 04 04 04 04 Uivl VrvI VroI VroI 04 04 04 04 oo ao oo oo 04 04 VI VI 04 04 roov rooo o oo o4> o4> O'O' *>s1j U 04 VI VI 04 04 OO OO o X m -n ro X m z o ro to o c VI -P* 'O tv o g: X i Z -i 8 ox to a > H ro VI IV H H* o rv ssii sj S| O' H* VI tn O' 04 *!> -p* 0> CO o n* c x* X rn Z^ --4 * 4) rv o * sjM o ui s| o >X O cXm zj o Z l_ 5 o ro Xo> HI --i c-- N rn 04 X a sj rn rv to y> <3 rn Z rv > o o X cz o zX --4 ft* C3 ro < Hm rv r* Vi o Vl X 04 z 0) ro z --4 O rn X 1 X m z H to n -4 X CX ao wrn Z hi V) n Q HI zi H> Ht r > rv -I hi >O zo z H HO WX OM H O ^H 1H O -< X J> to 7Z rn r-- r* r0>3 o X > -H o X -< 4> (V) VI Vi O' o Vi o o o rv O' 'O Co VI 04 Ol a* CO O' 1-4 s C O' C* -p SI IV rv 04 a 5: m St sj sj 4> IV Ol 4vO> IV o IV 0 O s| Vt Ol X o aa xi oo o O I- x -4 Z Q 04 VI VI O' oo o 1-4 O' s> si IHvVO* VM00I N o> O' Ol sj 3 o> --z4 nH 3C > 8in 4N 4> sj rv rv oi x> G> eL6ZfrKisodna 19 z w 3 o u ^u <0 < v* m a md a 1 IX qa to n o* IX 1JX CL 1 to Ui to o o a a X CCMO MO3 <UC*>> irj mrMo3 tho0 M> trOol' C<Mo Hto OM' <oo co siHr hOOo _<1 >" a- Pa Pz I* hs H ion iroH- ****** ZUezeu>gg Ui a5 oh* MOin3 to NCM CCOMO* OMCM' m to rH O' <too0 ro O<tf*l Ou CHRONIC INHALATION TOXICITY STUDIES ON T I0 2 AND TIC14-CDSP CM ' eeDugg CHM N (0 r>. <o to O CO <a30**: o 5o oi- * a :gu oo oCtOM oCtOM itno tino o oCfOM in 10 ootCitnooM oitarCnooM CittonooM ottCuooMt oootmtoo rootinoo rirnoo zUoJ ait *0'^0 <O'*0 ooo aoo 22 Ul G uo <0 <0 MUJ Uh-Jt J _1 V) 3 33a. cr> a. 3 CL CL n. a to to CL a3W xt o acw 5 << oc UH-zgJ rUr<-J ck <urh *i <U0l o >a VUo)i dc cueogi X << Xu Xo i < Hco Haui OMm o<ui X g Xh gg O p >- o CO H3 < 5u< UHi 3 oo M Xo H 1255384 PROJECT 372929 AUTHORIZED AMOUNT DUP050447914 0-6X48 CR&D ACCOUNTIHS tIpo I<P0 CU UJ 58 0. 5S v8 >- H* I DC IH <f O UH H MU < Xw DO0<3C OJ~ 2 H Q2 ~J O < X < Jto X <X zMO2: u to M UJ 2o Mo a: z> 55 h2HI Ui o So B" o *2 OC DC Z> o <h UJ o o o rS cu DC O o z> IP ro to o IP ip IP to to to to Ui u 2 UJ o: Ui U. 16 658 O' *- O' M r-) U <0 u> to oo o ro cu PI to to to IP to ro 43 <M HH IP tIoP o l-l o Moo DUP050447915 AIRMATIC TOOL COMPANY A IR & ELECTRIC TOOLS REPAIRS & R E B U ILD IN G TO O L ACCESSORIES IN D U S T R IA L V IB R A TO R S A IR BLASTING SYSTEMS BELT CLEANER SYSTEMS VIBRATO RY STRESS RELIEF DUP050447916 N 30812.1 G-77-C REV. tO/78 ,t) C1X, j /J '. THIS MEMORANDUM Carrier is an ackno"w"ledgment --that a Bill of Lading hat been (sued and is net the Original Bill of Lading, nor a copy or duplicate covering the property named herein, and Is Intended solely for filing or record. SCAC-SC AC -SCAC-SCAC-s Date -SCAC-SCAC-SCAC-SCAC- SID NUMBER MUST BE SHOWN ON ALL FREIGHT BILLS AND CORRESPONDENCE Shipment Sin-$lO-StO~8iB-S10-CIO-S*f-eiO-lO EID- Identification Number P-SIO-SIP-SIP-SIO-STO-BO-SIP-SIO-SIP-SIP RECEIVED, subject tooc*lassifications and tariffs effect on data of issue of this Bill of Lading. AtpfiiacT'"IsewatSc, Del. 19711 616D Of'ONO'. cooc FRSBXXmPOl DE NEMOURS & CO. (INC.) DEPARTMENT Customer's Order Number(s) lH-11564 Carrier's No. if charge! are to be prepaid, write ot name here. "To be Prepaid." M/A Theoiooerty described below. macDareni good order, except as noted icontemsand condition of contents of eachages unknown), marked, consigned, and destined as mdicatedbelow vuhichsaidcamer (the word carrier being understood throughout this connact as meaning any person or corporation in possession o! the property under the contract) agrees to carry to its usual daceof defivery atsaid destination, if on ts route otherwise to deliver to another earner on the route to said destination it is mutually agreed, as to each earner of all or any of said propertyover all or any oornon of said route to destination, and as to each parly at any time interested in all or arty of said property, that every service tobe performed hereunder shall be subject to alt theterms and conditions of the Uniform Domestic Straight Bill of Lading sel forth o t m Uniform Freight Classification in effect on the date hereof, tl this is a rad or a rail-water shipment, or (2) in the applicable motor earner classification or tarifl if this is a motor carrier shipment Shipper hereby certifies that he is famihai with all the terms and conditions ot the said Ml ol lading, including those on the back thereof, set forth m the classification or tariff which governs the transportation ol this shipment and the said terms and conditions are hereby agreed to Dy ihe shipper and accepted tor himself and his assigns IF PREPAID MAIL FREIGHT BILLS TO: HO B.X. DoPoafc dte geaaoors & QUl Edgesoor Plant ________ SPCC'-STLC S^CC'-SPIC-SPUC - !* 244% [ 3PLC-SILC-3l'LC-SPr-C*SPLC g State City WiIslington County Delaware s3 Co./Bob Buchanan purnvr DST>ivAiiRhruDi Zip 19898 | Delivering Carrier (If Rail) s C- Ac t SCAC"SCAC .scAC--5CAC-SCAC -SCAC-SCAC- FOR CHEMICAL EMERGENCY SPILL. LEAK. FIRE. EXPOSURE OR ACCIDENT c a l l CHEMTREC - d a y c r n ig h t 000-424-9300 (TOLL FREE) WASHINGTON. D.C. 483-7616 OUTSIDE CONTINENTAL U.S.A. (202) 483-7616 Repetitive Pattern Coda na pp c. pr RPC-r pc . BPr.. upr-BPr. bpr. bpc -r pc -bpc Vehicle Initials & Number If lower charges result, the agreed or declared value of the within described commodities is.hereby specifically stated to be not exceeding 50 cents per pound per article. DUPONTCODE BOMBER OF TYPE OF COMM. COOT. PACKAGES PACKAGES HM DESCRIPTION Of MATERIALS. SPECIALMARKS, AND EXCEPTIONS STCCC0DE WEIGHT SUBJECT TO CORRECTION Qu UN3 DUNS OuiMA-OVNS -DUMft OUtoS-OU N-PUNS-PDfia-DUNS-OUXS-ODMS-OUNSSNSulgeet 10 Section 7 of conditions of appli cable bill ol lading, ii this shipment is to be delivered to the consignee without recourse on the consignor, die consignor shall sign the fol lowing statement. The carrier shall not make delivery of this shipment without payment ol freight and at) other lawful charges. E. 1. du Pont de Nemours & Co. Ppt ISifnaiurvof Consignor) 8 DR Titanium Dioxide in water (Tit 4500 Lb. SPECIAL CONDITIONS _____ SHL Shipper Load Rot. recrulated b? D.O.T. -------- C0U Consignee Unload -------- EXC Exclusive Use -------- SSF Single Shipment DTI_________Minutes Detention i Other (specify) GEN.LEDGER 5479 SUB. ACCOUNT 3S-103-aMMHt (Rail, Cargo Tank, Portable Tank, Freight Container) GROSS PRODUCT WEIGHT Q Placarded Name of Placard (Truck -1,000 lbs. or More) GROSS PALLET WEIGHT ( . PALLETS @ Placards Required GROSS SHIPPING WEIGHT This fs to certify that the above-named materials are property classified, described, packaged, marked and labeled, and ere in proper condition for transportation, according to the applicable regulations of the Department of Tronsportotfon. E. I. du Pont de Nemours & Company, Shipper i Per_____________________ - ' : Permanent post-office address of shipper, Per MODE EQUIP. TERMS LBS/PALLET) SPEC. Cl R. SPEC,TRAP. DATA 4500 lb.811 lnRAt0DsAI3oNelStisSMcPEmECpCTtO>iRo0RnNEaBCnUToRSEUwABUeJEiSgCAhTCtTCOmOVoREDicRINaIFGieIC1dA0ToIAOnGNRmBETEsTMHEbENiRTuAoHr- Agent 4 DUP050447917 N30812.ll HI MILLIPORE EH CORPORATION NOTE HFW REMIT TO AimUBHS WORTHINGTON DIAGNOSTICS DIVISION OF MILLIPORE CORPORATION wij, i&. ujorrr-timoron T YOUR ORDER NO. |. \) H is 4 & } 4 4 3 ---- ---- REMIT TO: SORT 8333 . MEW YORK? NY 100-13 DATE | p 4/29/31 : SOLD TO: 2161 70.109 (DUPONT S CO ELK TON ROAD . HASKELL LAP NTWAf-cK 7 pr 197.11 OUR ORDER NO. BT OE WH TC TERR | | UMUDSiJSI--^ i,(. p93G |1 US A TFRMfi- ME T 7.0 0 ft Y S SHIP VIA: UP F.O.B.:BEJ:F0 LB? HA SHIP TERMS'R SPATP 1 AWTO CARRIER REF: SHIPPED T021617 0 1 0 r jlUPOHT 3 CO ELKTON ROAD HASKELL LAB ;J t-4 k 9 ) m fi | INVOICE NO. 4TEM-. --.. vUDUANTTOL....... NO. , SHIPPED . .L _ _ DESCRIPTION -- (unit of measure) LOT QTY. LOT NO. 15 f T S tr-. R 47 HH A ft Up- JOO/PK u p s ; p r e p a m:* l a d b e x i DRBER COMPLETE ' CATALOG NO. o -r/oo .... ..UNIT P.BICE,.... . . SALES. AMOUNT S./C jJ CL r ; 35" u . .. ... J5- -30-^3-37- <99 a 9 ACCEPTED SUBJECT TO TERMS AND CONDITIONS LISTED ON REVERSE SIDE I CERTIFY THE ABOVE BILL IS CORRECT AND JUST: THAT PAYMENT THEREFOR HAS NOT BEEN RECEIVED. ^/ ', BY------ ,-------------------------------------------------------------------1J. au t h o r ized r epr es en t at i' DUPLICATE INVOICE DUP050447918 N 30812.12 CONDITIONS-OF SALE 1. ACCEPTANCE -- Buyer's acceptance of this invoice shall create a contract subject to and expressly limited to the terms and conditions contained on both sides of this form. MILUPORE SHALL NOT BE BOUND BY ANY CONDITIONS OF ANY OTHER COMMUNICATION. WRITTEN OR VERBAL. UNLESS EXPRESSLY AGREED TO IN WRITING BY AN OFFICER OF MIL.UPORE. 2. PRICES -- All prices are firm unless otherwise agreed to in writing. Mini pore reserves the right to change the prices and specifications of its products without notice. Payment shall be 30 days net after shipment by Miliipore. Accounts not paid within 30 days shall be subject to a i percent oer month bookkeeping charge. Miliipore reserves the right to piece slow payers, those buyers ;visa accounts rema n more than 30 days overdue tor s period of snore than 60 days, on a C.Q.D. basis, unci to refuse to sail io persons until their overdue accounts are paid up. 3. TAXES -- Any tax, duty, custom or other fee of any nature imposed upon mis transaction by any federal, state or local governmental authority shall be paid by Buyer in addition to the price quoted or Invoiced. In the event Miliipore is required to prepay any such fax, Buyer will reimburse Miliipore. 4. TECHNICAL ADVICE -- Miliipore may. at Buyer's request. furnish technics* assistance, advice and infor mation with respect to the goods supplied under this contract, and lo the extent that such advice, assistance and information is conveniently available, 11 is expressly agreed that there is no obligation to provide such, information, which is provided without charge at the Buyer's rise, and which is provided subject to the limited warranty of Paragraph S be!o>. 5. RETURNED GOODS -- Nc goods shipped under this ccnTac* may be mh.without express authoriza tion from.Miliipore. All returns are subject ic a restocking charge No returns wm be authorized more than 120 days after receipt of goods to Buyer. CUSTOMERS SEEKING TO RETURN GOODS ARE URGED TO CALL NEAREST OFFICE FOR APPROPRIATE INSTRUCTIONS. 6. SHIPMENT -- Unless otherwise specifically provided, all shipments are f.o.b. point of distribution, and costs of shipment are borne by Buyer if such charges am prepaid by Con.'nantai, Buyer may be billed tor them. 7. FAIR LABOR STANDARDS -.. Miliipore represents my! the goods pfodur;?::'. or as vices performed covered by this invoice were produced and/o* performed in compliance wim tee .(fovirernanrs of ail sections of the Fair Labor Standard Act of 1938, as amended. . 8. LIMITED WARRANTY -- Miliipore *g.r)*e.ris so its customers that 'Ot one .mm from Ham of purchase, all goods and services provided by this contract will be of cocci quality and workmens h'.o. MiLUPORE MAKES NO OTHER WARRANTY, EXPRESS OR IMPLIED, THAT THE GOODS OR PRODUCTS ARE SUITABLE =GR A PARTICULAR PURPOSE. MiiHpore's sole obligation shall be. a: its notion to repair or replace any goods which have been determined by Miliipore not to cor fern to Millipora's spec-lications. This limited warranty constitutes Buyer's exclusive remedy, and will not be deemed to have failed of its essential purpose so long as Miliipore is willing and able to repair or replace non-confomiing oarts. fWIHoo/s accepts no liability for incidental or consequential damages arising iron non-conforming prcducis or services sold under this Agreement. 9. EQUAL. EMPLOYMENT OPPORTUNITY- -- Miliipore is an Equal Opportunity Employer ft does not discrim inate in any phase of the employment process against any person because of race, color, creed, religion, national origin, sex. age. veteran or handicapped status. The Nmiipcre Emm Opportunity Certificate, which is mailed annually to all vendors and vendees, is incorporated info this contract by refefence. 10. EXAMINATION .. Buyer will be responsible for examining all goods sm wider this contract and notifying Miliipore within s reasonable time. Reasonable time as esse! hem*": is io more th.sr- 3D days after receipt. 11. GOVERNING LAW -- The laws of the Commonwealth oi Massachusetts. U and any actions arising under it. smrd govern this contract 12. DELIVERY -- Miliipore will make every effort to provide prompt delivery of ;?:1 gooes, and services, but accepts no liability for losses, general, special or consequential damages due io delays 13. TERMINATION -- Buyer is free to terminate this contract at ary time, either in whole or in part, but in such event Buyer agrees to pay appropriate termination or cancellation charges. DUP050447919 ..... ................ ...................................... ........................ j/k+i. '/> `St YY[#A /<f/ *&vuC* JZj'b 5f0 $ ~B0& 3t Tf, Jf J<> Jo Jt fS~ ,'JQt& . 3c> >J?<& . so / 3<s> ! $o iJc> '3o *>,3tf ns &$ z, m* /,osr sa/St DUP050447920 N 30812.13 -A,(Uj&j : /6L/ >" ' /42^<3 rrf 'f/ 'St t$f 81 $ vre Y-YSk | ? .' 3SST 3>$ J?f 9-y 3! 3o 3f #> ^3kYk 3a 3 So 3z> ,3& ,3a 3 '7/3* *7, tn 3', /*?C 3; ago f, <Tdd DUP050447921 G-4& REV. 11-59 Tj n. or* 9**.<a o* Sy u o y ,, ENGINEERING H* Xf z-f > c o mp u t a t io n s h e ; -64*2 . fVvj.i or? S'tMsOY O'o _ Da y s 1', lf/v lift i(j>^Q ...... J2*~. Qr^ 73 O a & f. </w . 33,JC ^pfc~ ^W>TM~ 3 3, 2*4 K ^ ( h- t^W ' 3* ^ J^Ftih V\ ^Vl.^u/ i. ? (%a/ *3 6. W* /;3 z, ^f- V1 C-l -'-T \ ` { . \^ N ? ^ ' - V ;v'V * \0tJ J*w \ i\< -:i< /i'V -v *> 1 --- ; -- / /` JyUlsto 3. & 2-4r~~ *-*U 34i 2-#-|*r_;i..h * ^1 V/ 7 , ^mii^iiii .<;<ri.uyl>. J aiv*:/i&c: /Y X7/~63 Sf3i^ 36^' . . "T?5r?v. '4- UP ^ ^ h~ ?'7 SAVE T[NSS~OSS 'rHE STANDARDS DUP050447922 M Ift 8 a* rm-3i aa ou R * UI *5 CM sa- e JSbJ M3 CM * D O H* LA o H W CM O' CO rl O' CM IA *1 CM CO CO N M3 *6 O' -d- H -O 0 CM O' N a* o w *-r Kl c? * 1-4 'O IA CM CO O CM N 1 H CO a rl O IA o u g Is O' *1 N CM Ift O' O' CM I-I LA CaT* rs. co E < * 0! : o Kl K UI :Sae R rs a m iHn N CM O LKAl O<f in * >- 8 >- H 1 8 H Mf UH XW 1 P*- 1? I X o la 2M IMU OO OXUS Xt(0 CM N Kl LA O' <* in O' h CinM CM Mf O o Kl o *o X 2 :S U u i U 2 UJ a CJ CM K> Kl K) 8 LA LA k i ro onwowowo CM CM <J CM MA Mui Ml aKl al <1* o <it M3 0 *0 M> CM in CM LA H Kl rl M ook i oOotn MLA MIA QO 82 83 UO CL Ui to LA tO (A LA UI zin LU Hi IU H IU UJ WH UJ H a UJ X X X x X BU CL a. a a X X a a. c l a. CL X X XX X (A (A to to to 8 *9 <* *9 * I X X X tn < < < < < tu 2 2JH H HI HI H u UJ ui CK K IU Ui OS X Hi > h h H*.H H tn < < < < < Ui X X X X X 10 (A (A > CA U uC9i u(9i Hi &< SS > x < XX ro Ut UI X L> U LA X -J Ui o u UI c zo zo (A Kl tt UI I IU CD < Hi Hi a (A (A >- M >> tA H > < 5 (A LA Xa O ui > o X <o (J LU UasJ H (A Mo aH HaI w >to- X tt I 3UJ UJ UJ K g o z o H il < CO O* K Kl I O' N- O HI z 3 u < U H z u < o X o < D U P050447923 N 30812.14 MJA O' D- 6 1 4 8 CR&D ACCOUNTING :i5 tO a Is 10 o CM IA sO CM *6 U) s MO W w CM tIoS Is CM H * O O CO K CM to CO CM * G* 1A IS 10 o <0 o o CM o CM IA r R* h iH s CO to H O H <0 IA IA is H O CM K1W H O' I IS H *0 W O u W <0 HO' eo n >o <r 't CM CO <0 is10 c m m m sO o sO H O' O' O' >* tv g ow < XM PK 8 22 -3 o < J P CM -J < O *5 < P sx woz om w2 UMi OO axo pcPo RSI* m in Ui a o CO a si* CO to o IA4t S CO rtw to CO o 0* CM foc o CO CM H <0 IA sfr CM to e IS R * rtsO CM to We w so* CO 8 s* N W CM IA IS H <r c m O' CO 0 IA os : * U02I ;i UI i ao H to sf CM t? 2 CM vC CO CM N U su ws 8 ffi IA to a 2 UI X LU x O' i*l O' 10 W CM N to to ao tO CM to CM to ttoo tO to to to IA to IA to IA to 1>00 iA sO I COM O' CM O' CM r-* to >- J- 8> I 5UI > gt2IUo -U4t gCL -J X< < CO b! 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CM 3 CO CO O' CM m to 1H CL 9 ir? >c: W 'Cto uw w wu < XH a OW ow it <ft Ift O' a o CO H tft CM to c? to o u wz CO o s wz Ul 0 X 3 o CO 'ft w OM>'0 1ft to s| covl CwO tO CM O <U0l K tO a O to O' (0 wN 1ft H (0 H O' CO O' W w w R r-l o 'O CO CO 0 <0 CM o S o 'Cl ift I <au.i o 5 tO *Ifftt 5 a O CL < go aDC `3 LU O O O o o o o o u ooo o ooo o c: o o o o CM CM CM CM 1 to to to tft Ift 1ft to Lft to IO to 1ft lft tft to lft to to JO to to to to to oo ooo to to to to C1Mft CtfMt ICfMt CIfMt 10 to Kl |ft **fftt ^M3 '0ft 'i* CM Ift CM Ift H tO H JO HWWH X XX Cft to to (ft (ft (ft to IU LU UJ ui ui Ui ui X WWW W WWW J J Jtu a. 3 3 Xx oa.. aa. aa.. to to to _J 4 JU a. o l a a. a. a. a a 3 3 33 to (ft (ft to a. EL 3to o s &* I t < < WWW _t -j --i < < t WWW tUoI o d: dc a uwi twu UwJ DC OS DC UJ UJ UI WWW <re<s< <c e g^ oo o oKl olO tft Ift to IO t1tooft ooo oao XX to ui "5 X HW . CC u! 3 >Ul (f<t <to E < EL < -J <o DUP050447925 Neg 1U I 5 EX tx o >- o >- h a HU <rHf SH o PH CO 3 5 Jt<otC < H-i HI 1= X HO (J V) H 111 ZH oa U CO UI P 1 IU H < o O H I !" H O o O' eg N <* CO Ift H O <0 CO CO CO H O r* N H 't Ift r-l k Ift eg in i** . H O o* Ift H O H O o CO <0 N ift N Ul sl* g CO CO >0 CO $ N O Ift Ift $* N *0 Ift 1ft * r-l *6 CO 1 Eft Ift CO Ift HN cr 1". o Ift Ift <& UX <o X IU cc :g U *0 Ift CO <0 O' O' m in r-t ift Eft rft CO ift *H < *O o H o 0* eg <0 o <0 v0 0J O' Ift Eft O' Ift |C CO H >0 Eft Eft CO eg 1^* Neg <0 <g <0* ift CO HH ft* r*. eg co <3g <> O' in egO I Ift r- O' g> Eft <Uh-i to B? o X oE EC :S O Ui a s o ir> sf h 10H O' o IMS S0 Eft CSJ vin> I H O' O O o ift o Ift o eg ift o N eg Ift in K) Ift Ift ift Ift rft ift roift Eft Kl Ift Ift ift Eft Eft ift ift Ift rft ift ID Z P o CJ co < * r-f a \o a 1 06 ao Ift Ift I ift ut ift o Q CJ O X iu 9 Ui m- CX 3 3 5UJ H O W>ex 888s< o 8888 H 3 H X o HH X o S X o IU X CJ Ui 1 < 1- h H H H a a. CL 3DC o SS <c o m IOiSft' oIaft* oe o zu(0i a j V> O O' o x b CO a u s o Z Eft H n-con H < EX eg u DUP050447926 a <h {D < O. CO O' H >Oi >- g 6 X O < z CO 10 in ! / .4 S -n b iu o X CL iH < $ ' Q CO Kl d* COKl sO o Ck S Kl CO Kl CO 8 Kl CJ rH UI <T CSI CJ <0 to oo H rt * Kl in o Kl Kl UJ u co <i* z O' o UJ ^ in X oo UJ o u. UJ X o oo o o ooo K Kl Kl Kl CJ CM CJ CM to in ui in Kl Kl Kl Kl KC*Jl in O <? O in m K> Kl o o o to in Kl aa ao oo 23 oo Kl m CO CO CO >* >- CO UJ LU ui XX cuoj ucoj u CD CD CO < < <{2 act: or a. XX x Kl uo u UI LU UJ UJ UJ UJ CO Kl 3 s o< UJ X X 3 8 MW -J _J LL a. CL CL CL U O L) L) Z22Z <<<< zzzz o z< z UJ o CD tow X CO CO gg 1o CO U-UaJJti CO3 3CO 8 8 M<-U<XhJJ* XH<-<MUJJ to -<wUi<XJ-J -<HXUH<JJ I CwUu>XUCOOJJ tttHUJ UJ UJ tu HW g z<<H <z<H < lx LU Q O H CQ MW >> WM QO 01 X UJ UI ro zo oo w> H 0 X UJ h o UJ X CK esi oCJ N ki i <K h* EE .J < L> -J U E < o H z < o < X >in CD oO .j oo ou IH IH XX oo H H DUP050447927 1if0r D-6148 CRKD ACCOUNTING ui md Si m o s CM H o N s3* CM '0 M3 so C0 CM co <r to H IO p* O' o CO to CM to *0 O CM to rH 0* cr o h- CO co to H O' co to to sO O' sO i-t o o m < to CL rH CD CM rH O u H 5 0s to oH 10 O' to 10 to>- u z s0 CO < O so MT * z co O' to to CO CO N CO O' O' CO to <fr o* O' CO s <0 0 :g 'o 5 o CO CO <0 in >0 a sO to CJ CM a in rH r- to r** M3 o t- SO CM rH N0 CM <? wm rH w CO CM <0 <r <o to o* tO tO CO Oto' m CL s >- H* I K H <f OK OWOW < Xw OL Oh OCQ H O < oz <zc < ot-- CM o UJ <-J Ht- Er5 < zz X HO !z U-J E *o CO tttooo CM >LU tu > DC * 0 o* Z> LU :5 0) KO SO' CM x-o tE d: :g o 10 v0 s0 o so to o COM to itno oto otitnoo o z * to in O' CM e0 '3* I O' w CO in O' O' O' O' to ooo H CM to 0* O' to 0* sfl* o Kl 10 o o rH CttooM IO CtoM itno oto tCttoooM ottttoooo o CttooM itno W >* h -j or U < _1 3 Ui (0 UI to Ui > < X tn Ui to tn u z _1 Ui Ui 1X1 X u t~ <CL -J o w co i H* > UJ O o o <o s IU >- Ui a. tn o to tn oo < iu O tn -j o o IO o: H z CD O' >- >- >- I S3 CD Oo tn < >CD CD OO 8 *o4 u u zw oin: 0o H 8 W 8 .<J EoO' CO s s X u E 1g CO p o CL CL u DUP050447928 DUPONT BE NEMOURS (302)790-6606 r-fj e'.3> cv w.. 8r a &)> 50' -o8 <Sn2 3cTSa)-. k f oS -co d lf3 d a g at b<3 secc *-r*t 3K < ii! AO- T0"} 0 1 j i/i x --a. i~o oKb~s US 3C fl* l DUP050447929 N 30812.15 OVERTIME ACCOUNTS ARE SUBJECT TO A LATE PAYMENT CHARGE OF 1W% FOR EACH MONTH, OR PART THEREOF, THAT A PAYMENT IS OVERDUE. CUSTOMER DUPLICATE MELCO, INC. i s toO-JQ HO .QJ I 2o a </)S --tL HO DUP050447930 OVERTIME ACCOUNTS ARE SUBJECT TO A LATE PAYMENT CHARGE OF 1%% FOR EACH MONTH, OR PART THEREOF, THAT A PAYMENT IS OVERDUE. CUSTOMER DUPLICATE MELCO, INC. to 2 >n: z -Ct "> CL 9 Q >* U >- t- I os: h <r o OH < HO Xw o: O to 0 < zo z< 'M H CM < in X < zz X Ho a to H Ui ZH g X hU to fe UI CL X CO to U)CL If) o 8 V- Xz u3 tx O < CM z UJ V) O CJ < UJ h- a tx. to UJ M -J h* M < o ck a IU o t z 2o2 5 UJ n: 3 u CL < UI : o *o ! to sO <0 r-t W<0 oo u< oz z I-- z Ui Cl' IX . 3u ' UJ :5 >o 10 D U LU -J X -i tHZ CO ZO N O' o CM CM 60 iH to toCM srIO H sfO m to 00 k D rH IO If) Ho tO O CM o Kl CO Is* N fC CO CO rt IO M UI 10 CN 60 t*IOo sttooo tCtooM UI H< to tx O 3 h o X o *z z O' 3 u 3OV) o oo CO CM fiOn tiOn K) tO MtOIOM CM CM CM CM in ui in in MWMM 'O <f >0 <f O -O so MS c m in c m m HMrtM o oo otitnoo titnoo oa oo 2Z 3o UJ to to to 10 to UJ UI UJ UJ Z UJ M _) MH _J -J H -J a a CL CL a. X CL CL 0. a. UJ 3 3 3 3 to to to 40 u. O 8 *6 <4 08 to -J -J .J H < < < < Z w J-J >H M UJ X o: o: o: z UJ UJ UJ UJ UJ h* t-- j- - < << < UJ Z z z z in to Ui UJ to to to O' E Oi <z < < < XX X o uX u <LJ LU UJ LU yz yz uz uz < < < < zzzz u z z u zo zo MW to to zo to oc UI UI Ui Ui MM I-- I-- I-- I-- >> z z zz l-l J--t M M M t-i O 3 gggg -I -I -J _l CL Ui <r <r z< <r gO 3 3 CL CL o Z Z oo oo o If) DO' CD z 0 ouu< o N K> DUP050447931 N 30812.16 tO w D-6148 CR&D ACCOUNTINS tu to 2 <0 o H > K 3 5 "> a * o >* u L-- l M O ft WO XM OH t-- 0 o s<< z z -J _J L-- CJ <o lu -J -) X <w (A X < zz X Wo O CO M UJ zw OQ XX X >-- U (0 h Z JE x< a vfr CttonO LA W z a ) N < h* M UX DC UJ O h* Zg5 O. < 5 a O' H CM to IA 4tor H CJ to fs CO o <* o n cO is to CJ vfi & LA o L-- h*. <o to H CO IS LA to LA |s LA rl to o 1- h u z ft O' < o to LA X v> O' L-- *Z * LU *X * (Z * => u o ft O' rs o to to CM O' ft *> rs LA n 0 LA *A o IA O IA <0 v> <0 to LA H < o <0 O <0 co 'O ft to cm r* fr LA sO oOO ro rs rs o h* IA CJ H to eu ft O el to ft ft vO CO o o to *9* CO 0 CJ LA CO to is. -J X ~t Wz o o 0 O N0 o 21 O' to K Z UJ X -X D * uw M CJ t * UJ 4 - < o rs a to O' CO CJ <h ao O' X o r o ft H X is X 3 U LU o O O CJ to Xo o Z> to to o LA LA CO to to UJ a z LA IA * LA IA LA IA tP <? O <0 is N O' rs to tO to K to to toIA LA LA fA t0s0 >X >UJ LU <to UJ X CL u X H > <l a a X UJ UX < < UJ x > co (0 I- UJ o I> \ >z o u to>- >- to os o 5>to- o Si O >CQ O o S z >z * > o-J w M CZ -J s <t <to to o2 oa W --I X Xx u o a. h` <0 2 O LA O' LA DUP050447932 INVOICE \".jf , ;K rr :"'HiI-. yV. .. pr : I/O o T j ORDER NUMBER CUSTOMER NO. , . . - .iLHS;UiO i 7'-;6 o6Ck i i I. v. ;ii K_! UfetS/SUppllOl s i!xJu,irii >! insruuriona! uniforms disposable apparel NO. OF CARTONS j SHIP VIA DATE PU-ASE REFER TO THIS INVOICE NO. WHEN REMITTING AND WHEN YOU ARE MAKING ANY INQUIRIES REGARD ING THIS OROER. INVOICE NO. I CUSTOMER COPY MEICQ, iNC. DUP050447933 N 30812.17 INVOICE t .1 V L .1 UPDK LA 8 DC, 01" riEnOi.'A (602) 790-6606 monufoaure s/suppliers , indusiriol uniforms cii.s|.x'!siii ;k' apporel i ONDiil? NUMiJlfN j CUSTOMER NO. j I/O NO. OF CARTONS 'TiV/.yV-'V SHIP VIA DELVD DATE Wj V 19 BO PLEASE REFER TO THIS INVOICE NO. WHEN REMITTING AND WHEN YOU ARE MAKING ANY INQUIRIES REGARD ING THIS ORDER. } INVOICE NO. ^ j 833.00 033.00 *F4\*oTc:E6;rdTAL OVERTIME ACCOUNTS ARE SUBJECT TO A LATE PAYMENT UIARGE OF Vi% FOR EACH MONTH, OR PART THEREOF, THAT A PAYMENT IS OVERDUE. CUSTOMER COPY MEICO, SMC. '' ' 333.00* 1 DUP050447934 1 U U l UU - UIU J. vs ORIGINAL INVOICE ii s El DUPONT DENEMOURS'Bc CO. HASKELL LABORATORIES ELKTON ROAD ' / NEWARK DEL 19711 107 'Hi 'V, -I. Ill- tj> lljf- # ;S 'i'-'V) 01430958 -wo s,.... bs ooi h e m Huuotri ,;DC100S ...jDCiOOM JBC100L Id c io o x l j >[tyA l 297789 r-nii-tiO; UA|ilTIfVs mii-i H 4 10 66 10 10 ics cs cs cs rHHlr -r , 1114PM 11/17/80 L0H6717 .CittllWAla S> IX 10 DAYS NET 30 DESCRIPTION u n it piiicr AMOUNT TYV ZIP COVERALL SMALL 25/CS TYV ZIP COVERALL MED 25/CS BACK ORDERED 8 |TYV ZIP COVERALL LG 25/CS TYV ZIP COVERALL XL 25/CS *** *# SUB TOTAL ***#*# 40. 50 40. 50 40. 50 40. 50 162. 00 81. 00 243. 00 405. 00 891. 00 nov m PRICE ft rERf* OK ____ EKI&NMUJ1 r -Y1TH V> ////sr, APPnOVAt] QQLct PRELIMINARY AUDIT FINAL AUDIT ^V79 ,, $>-30H3- 3l-a9S% eo 35-30^3- 3&-3t<0- 46t97fc> 35 -30H3 - 37- 3G 8*3 #<397 > 2IF PAID ON Oil BEFORE 11/27/80 >YOU SAVE 8. 91 SI 111 R REPRESENTS IHAI WIIH RESPECI U> III!. I'llOIJUCIION OF THE ARTIOI-S AND/OR IHE PERFORMANCE OF THE SERVICES COVERED BY DIIS INVOICE I! HAS IULIV COMPLIED WITH IHE PAIR LABOR MANUAHUB A! 1 Ol IV38 AS AMENDED NOOISC.ODNI All OWL r> ONDFLIVERY CHARGES OR SALES IAX. SAIESSUBJECT TO All IERMS ON THE REVERSE SIDE HEREOF. DUP050447935 00021 020020 ommrnL in v o s c e . -.J : U,v*-k . 11 Wi'O't. r !l.: w. ; :. 'JV'i : -J i ^ 01431246 . El DUPONT DENEMOURS & CO. "a * HASKELL LABORATORIES ? ELKTON ROAD L i NEWARK DEL 19711 .' j 107 AMI' AS "%>!!) I f >' I StJi l ?,$ INDIO a K {n <V^? hs'< ..i: vi>> AND/OR IKE PERFORMANCE OP THE SERVICES COVERED UY 1IIIS INVOICE II HAS EUUY COMPLIED WITH THE FAIR LABOR STANDARDS ACI OF 1938 AS AMENDED. SALES SUBJECT TO AU TERMS ON THE REVERSE SfOE HEREOF. DNFIRMINGTO: BY: 1 DATE: --n; , ' *" ' . EQUISITIONEDBY L. & Co// - EXTENSION REQUISITION APPROVED BY C -tyk'CZW 1 ../DATE AUTH. LEVEL MTEOEUVERYREQ'D ESTIMATED WEIGHT VPYfco X0 ESTIMATED COST TEM NO. GENERAL LEDGER ACCOUNT/ SUBACCOUNTS _____cLrsmffla.___________ AMOUNT 3Qi/3 - J DELIVERY SPOT# 3? . 36/4-. - LAST ORDER NO. OR SUGGESTED VENDOR8 ADDRESS 3 7 - ZCJ-3 - yL LOWEST PRICE nONLY KNOWN SOURCE ASONVENOQR 3 SETTER QUALITY U ` SELECTED REQUIRED DESIGN COPY 2 - n WILM.ACCT'S PAY. ORDER APPROVED BY < ORDER EXEl I-! LOCAL ACCT. SECT. 1368150 REQUISITION NO. DUP050447936 DUP050447937 in Ift K> U1 CL O CO O' U o a 8 a >- u s- a 1 ex w *d* H0- wU 0H < Xw ex O H0H IQ -- Q 22 O< <o < *-h i -J w < MO u (ft Hi UJ ZH oa O' 3 x hr u tft I-- g R a 2 IK UJ <0 m a in O in ~j CM UJ rH > UJ 0 08 HXZ O3 a O' O CsJ X UI O' < (ft CM UJ ft- a a Ift UJ N ~j H H <Ua R ur 0 ZOK ui a 3 Ua< UJ :$ K> >o *0 o fe 8 DX "Si * v * 2: a UJ * IX * 3u MNKl'tSW NrtNO'OW ST MH o ft-N IV CO <0 sfi CO Ift d- O CO O p H C0 ift sO n O H) O 0 ft* m pH rCO' O' rH CM pH O Ift Hf sO d- p H Ift pH CO z Hi H z 3 O CJ u CO < SI* HO %0 8 1 ex aa ift in O' a i~ X a t rft UI Ift 0 0 a S O' ift O' K> in sO o so i*l tft O CM CJ Ift Ift sd* m in ftft- to ro 0 in CO in w Ki p H o O' CO N CM .< Q * O *H * (ft o o Ift s3- O' O rft M3 O' p H in CO O N CM sr ft* rH p H in ift HI Z 0 O X * fZe ui ex * ex *3 *0 M W K -d-N N N H! N O' O Ift <r c m r-i *a-a* 0* <r N. sO sO N* *0 Ift N st *n iaft* <0 (0 CO CO o < H O *O lS K :B O 000000 O O 000000U o o 000000g CM CVJ CM M M M Kl M M ro Ift Ift Ift 8 Ift Ift Ift Ift Ift Ift MKlKlWMKl ift ift 1ft 1ft fO Ift 1ft Ift U 'ooooms Z CJKtsOCOCO<f UJ 000000000000000000ex oa oo oo Ift Ift 1ft Ift Ift Ift Ift Ift 8Q oo oo 33 sff N RSO CO & O' ft- in ift ift ift Ift Ift CO sfr 1-1 Ift tft 1ft Ift (ft U) (0 EK a< 5Ui Vi (ft (ft Cft (ft (ft (0 (ft (ft (ft UJ (O UJ VJ u us UJ UJ UJ UI IU UJ a UJ z H W Hi W HI HI M W H Hi 0 UI UJ a J J JJ c l a H. CL ft. XL a _J aa _J a X UJ z < X x EL CL a. a. a. a. a a a a X z to to (ft (ftUJ x 3 x x 3 3 3 3 3 3 1-- UJ a O (ft (ft 3 <8 63 S eS 3 to 8 (ft to 68 08 (ft 68 0 1 fc s < >X ift UJ uw in UJ z oo X X s?Hi Eft >Hi ex <(ft u HI aH >- >- < IU X X >UJ o o >- >- (ftUJ (0 CD oo (ft _l -J h- < ( < < < <C < < a UJ (ft z Hi z c O Hi (Q aa XX 00 CJ 0 a x 0 0 (0 (0 oo XX oo H- H > (XfXt z X Io g X DUP050447938 N 30812.18 lu X H to < Q rs to o h-. 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Is* 0O u OO ro ro CM CM uj in 8 ro ro o o to CM in ro 0 o oo ro ro in ui to ro o o o ro in ro o ro in to oo CM to oo ro ro m in to to IU o z q at UJ CK 2o 2o UJ Z 3 vO in CM ro <0 H Ul M3 O' CM H 0 CM O' o 0 rH H rH |s ro fi o rH CM o 0 vO ro to CM tO IO 5 |S b g : < UJ CL i ig g saLU LU 11} (ft Ul X LU U ro (ft (ft X CL o I i 8X LU CD X O' os 02 -J J- < o w UJ < > (ft 3 (9 W s 8 8mo (ft & 8 UJ gg 55 88 8LU UJ UJ HK <C W <c z w H* (ft >> WH oa o 1" u >* (9 >(9 >(9 >* CD > cu UJ (ft (ft OI >" >CD O >(3 O ax. o h ID to H > (X Ul (ft << MH <C h n. ui Q O S i0u2 iau Hh sc X UJ s p u Ul X M a o J o o M X p O ^J o o M X o I- o ~J o u H X o H O -J O o l-i Xo H- < o z X u h > X CJ IU h O X CO O X 3 (ft in h X < x h- DUP050447953 N 30812.2 IU 1 co O' rH I 08 fc? H <3* I UH HI O Xw Q! s 2 3 O< HH CJ <o -3 H <H 3 Z X HO O (0 M UJ ZW oa o: 3 sc t~ O <0 fe UJ p 1 m o ga s a CM ui > UJ Q 5 0 <C UJ to < 1 UJ o UJ o h 8 U !i :g ex *U UI 5 o :e to o u Ui --i x -1 H h";Ssc :fe IU tx * *u I O' CO o Ui H Q to tx o YO c o s * Qt : 1 CO CM rl a* i N <* O' 111 u g0 to Ui o z to UJ z IT| UJ CM nO UJ N. BOD-1420 CRSO ACCOUNTINS K) m DUP050447954 DUP050447955 N 30812.21 REFER TO SHIPPING ORDER NUMBER SHOWN ABOVE WHEN RETURNING GOODS. 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X IU b. o CO h z Ul z Ul mI Ul CO Ul H _! CL Q. X CO 0 J H OC Ul H <t z CO tCL UJ a DUCJ X h~ O 1 CO Ul a w > a tu CO CD CD << XX U (J zz QM OHi CO (O ww >tH >HI oo oc oc UJ IU h* had as: oo (J CJ CD DC < X u Z Mo CO tH H> O X UJ H" D a. Z o u (0 bi (9 IX < X u 1o UJ DC H o a <c UJ X aUJ > O >* 0 O ml o u H X o I- Ht mJ Ul > UJ < CO 1 > 0 ~OJ O O H X o *- H _J Ul >Ul ml < <0 1 V 0 O mi o uH X o t- >a 3 < 0 X u UJ h* r >0 o ml o u w X o 1" H u toJ 0 0 UJ uHI > cr Ul w mi a 0 5 Ut 1- Q < UJ X DC UJ > o >0 o ml Ow CO o < a Ht U>J .J J < cn i V CO o mJ o H 0 o e < 2 >_t < 0 X(_> Ul H1 0 o o HI 0 o P < a X S o Q UJ H* < CUkl tt oCD < >z oCJ L < 0 1o-- d; o w a CL 0 h 0 O o ll CO Z UJ CxL UJ ,J P to o *sf 0 . 0 oH fV i> 0 1 8 0oQ o O' ooQ 0eg 3 0 2 h K o oo CJ (J er < r-l ta a a o a: 0 O to 0 o a H a a. 1 uu to O o a a X DUP050447960 4L&J0 DATE ISSUED: B/nf'J^ DATE REQD.: S/3J m BLDG. NO. CHARGE-^...ZfiZfiV) -- . 30 fe/O WORK ORDER Es t . Co s t ^iC^OR^P ACTUAL. ma t l :--_. J TOTAL S32 /tTJ Co mp l e t e De s c r ip t io n o p Wo r k To;^L *(ZA&k )v 4^0 UtX- Ax j A C ^ c /(a flA-aibn-l u ^Cl k IT DUP050447961 N 30812.23 ... WORK ORDER DATE ISSUED: &/&//'9'7<^ Es t . Co s t ACTUAL d a t e mn ff;gair ^ LABOR^ Jg. ^"3$-......... BLDG. NO. ^------f MATL. ---- --Y CHARGE: 2 92 <?JS`^ "t o t a l ~~M. .<Vs&r-&J&Q Co mp l e t e De s c r ip t io n o p Wo r k TOu/,SiU.d/0 __________ ISSUED BYi ^ > nA.PrPWROTVnAwLSmANWD *D.AnT.>S * ^ah/r&\ Hffef'J*? jgjLAJLieJ- i+rVxA~ DUP050447962 4507 - 6lH 8507 - Grain Prepared fiv Approved By initials Date N 30812.24 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET A rtl M*T TIT I IT A__P___P__R___O__P___R__I.ATION _A__C___C" OUNT 1j 5415 p CHRONIC i n h a l a t i o n t o x i c i t y 1255384 ! |37 2929 I s t u d i e s ON TI02 AND TICX4-CD&P 1 S -I 1 > ) 1 ) ) \ J :> "i -j DATE MONTH YEAR i DEC J79 DEC 179 i l i i i l 1 1 i l i 1 i l i i l l l l l l i l l l 1 l i t i i i 1 l 1 VOUCHER NUMBER DETAIL OF ENTRY BAL 8R0T FWD CEV12-054 COMPUTER DIV CHARGES CEV12-0S3 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE 1 l i i l 1 1 1 i 1 l l l f l 1 l .l l i l i 1 i 1 i i 1 i l i i t i ! E. 1. DU FOC4T DE NEMOURS & C OMPANY. INC. EXPERIMENTAL STATION ORDER NUMBER AMOUNT i 1 jo 76 21 1X45 22 |22i l l i 1 1 1 l i i l i l i 1 l i i 1 1 l 1 1 1 l 1 1 1 i 1 l 1 1 1 1 1 1 l i i l l 1 1 l 1 1 1 1 ! 1 1 1 1 1 i 1 I 1 ! t 1 1 1 1 1 1 1 1 1 1 1 i BALANCE 249 j&27 271 1 I l l '848 1 1 1 1 1 1 1 l 1 1 1 1 l l 1 1 1 1 l 1 1 1 1 1 l 1 1 1 1 1 1 1 1 1 1 1 l 1 1 1 1 l 1 1 1 1 1 1 1 1 1 1 i i i i i l i l i i i l i i i i i i --------- r .............. _ rs S )| o C3 | )? ^i! ) ) " ) .1)1 ') .) JJ .} DUP050447964 N 30812.25 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE ............... AaPdPbRbOo PmRiaIAvTiiImOuN ACCOUNT n 5485 p CHRONIC i n h a l a t i o n t o x ic i t y -J155MLJ L3T_292i_J STUDIES ON TI02 AND TIC14-CDAP DATE MONTH YEAR VOUCHER NUMBER DETAIL OF ENTRY BAl HROT FWO ORDER NUMBER AMOUNT i BALANCE 228 i889 O 2 oz> oz> CEVH-0S4 COMPUTER DIV CHARGES 1 J438 1 CEVU-053 HASKELL RESEARCH CURRENT MONTH EXPEND 19 I300 20 |?38 1 1 1 3 e x p e n d s TO DATE 249 !&?? 5' 1 l r! 111 a 1 ) ;) } .) '5 J *) ) .) 4T DE NEMOURS Be C OMPANY. INC. j EXPERIMENTAL STATION i i i i i i l i i 1 l i i i i l l i 1 i 1 1 l i l l 1 i l l l i i i l i 1 i l l 1 ............ . I., l i l i i l i l i i 1 i l i i i 1 i i l l i l 1 l l i i i__ _____________ i i 1 l 1 1 1 1 1 1 l l ! 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 i i i i i i i i i 1 1 i i i i f i :> ) )i >i 3? \) hi ..) .) > Hi DUP050447965 CENTRAL RESEARCH & DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE______________________________________________ ACCOUNATPPROPRIATION I 1 5S5 r CHRONIC INHALATION TOXICITY 1255384i |37 2929 i STUDIES ON TI02 AND TIC14-CD&P DATE MONTH YEAR OCT 79 OCT 79 OCT 79 vo uc her NUMBER CEV10-O54 CEV10-054 CEV10-053 DETAIL OF ENTRY BATWW COMPUTER OIV CHARGES ANIMAL MAINT HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT l 223 33 264 20 468 54 955 BALANCE 173 1934 228 889 0 3 ') :> m 1 3 ) ) n\i E. I. DU PONT DE NEMOURS & COMPANY. INC. EXPERIMENTAL STATION m* DUP050447966 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE APPROPRIATION ACCOUNT Tj 5485 i CHRONIC INHALATION TOXICITY STUDIES ON TI02 AND TIC14-CD&P J 255384] i3T_J?929_j DATE MONTH YEAR SEPT 79 VOUCHER NUMBER DETAIL OF ENTRY BAL BROT FHD CEV09-OS3 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 26 400 26 400 BALANCE 147 534 173 934 S 1 E. I. DU PONT DE NEMOURS & COMPANY. INC. EXPERIMENTAL STATION mi' n DUP050447967 CENTRAL RESEARCH & DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE__________ APPROPRIATION ACCOUNT i j 5485 j CHRONIC INHALATION TOXICITY LJi?5S384 J [37^ 2929__j STUDIES ON TI02 AND TIC14-CD&P DATE MONTH YEAR AUG AUG AUG AUG 79 79 79 79 VOUCHER NUMBER DETAIL OF ENTRY ORDER NUMBER BAL 8R0T FWD CEV08-0S4 HATERIAt H03232 CEV08-054 SERV CHGS 0 0 TRANS CEV08-054 ANIMAL MAINT CEV08-053 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE AMOUNT i `180 1 |183 33 '264 28 1284 62 `911 i BALANCE 84 |623 147 534 5 H N I '9WX04 <5<t3NI<jr>9 IXO iCW m-nnwH<: 3 > ) J 3 I. DU PONT DE NEMOURS Be COMPANY, INC. EXPERIMENTAL. STATION }i i i M* i J ji :) DUP050447968 CENTRAL RESEARCH 8c DEVELOPED!ENT DEPT. LEDGER SHEET ---------------------------------------------ACCOUNT TITLE______________________________ APPROPRIATION ACCOUNT CHRONIC INHALATION TOXICITY STUDIES ON TI02 AND TICI4-CD&P 1 5485 T L_1255384J [37 2929 ! MONTH YEAR JULY 79 JULY 79 VOUCHER NUMBER DETAIL OF ENTRY BAL BROT FWD CEV07-0S4 MATERIAL CEV07-053 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 41 22 094 22 135 BALANCE 6? 488 84 623 1 :> m -) E. I. DU PONT DE NEMOURS & COMPANY. INC. EXPERIMENTAL STATION DUP050447969 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE.................................................................................................. ....... ..... APPROPRIATION CHRONIC INHALATION TOXICITY , i i 5485 I LiJSSlUj L3J_2?29_J STUDIES ON TI02 ANO TIC14-CD&P AC o MONTH YEAR VOUCHER NUMBER DETAIL OF ENTRY ORDER NUMBER AMOUNT BALANCE i*i 3 BAL 0ROT FWO 35 20 JUNE 79 CEV06-054 ENSINKERINO OEPT jSOO 3 JUNE 79 CEV06-054 a n ima l s p u r c h a s e d HOI993 JUNE 79 CEV06-054 ANIMALS PURCHASED HOI993 i 473 i !473 3 JUNE 79 CEV06-OS3 IHASKELL RESEARCH 3 CURRENT MONTH EXPEND 23 122 E6 1568 :> EXPENDS TO DATE 62 1488 1> 3 ) ") ). ) 3* ) *.} J .) .} E. I. DU PONT DE NEMOURS & COMPANY, INC. ,} EXPERIMENTAL STATION i< ) DUP050447970 CENTRAL RESEARCH & DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE_____________________________ r i APPROPRIATIONACCOUNT CHRONIC INHALATION TOXICITY 667170_l bj 2929__j STUDIES ON TJ02 AND TICI4-CD&P DATE MONTH YEAR ma y ma y ma y 79 79 79 VOUCHER NUMBER DETAIL OF ENTRY SAL BIROT FWO CEV05-0S4 PRINTIN SERVICES CEVQ5-054 HASKELL-RES ADJ CEV05-0S3 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 67 000 [68 i 23 748 BALANCE TTtl'Va 35 920 E. I. DU PONT DE NEMOURS & COMPANY. INC. EXPERIMENTAL STATION DUP050447971 CENTRAL RESEARCH 8e DEVELOPEMENT DEPT. LEDGER SHEET ---------------------------------------------ACCOUNT TITLE APPROPRIATION ACCOUNT L 5485' CHRONIC INHALATION TOXICITY 667m J i3T_29S9 I STUDIES ON TIOS AND TIC14-CD4P DATE MONTH TEAR APR 79 VOUCHER NUMBER DETAIL OF ENTRY BAL 8R0T FWO CEV04-0S3 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 253 253 BALANCE 3 (919 12 172 11' jJ 3 3 1 \y > '>( I '13 ii E. I. DU PONT DE NEMOURS a COMPANY. INC. EXPERIMENTAL STATION DUP050447972 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET Ar.roiimt Ti-ri rr ' Wl ,UI" 1 5^5APPROPRIATION ACCOUNT |--t -- --------j-- CHRONIC INHALATION TOXICITY STUDIES ON TI02 AND TIC14-CD&P 667I.70J [_37_2929 J DATE MONTH YEAR i MAR |79 i i i i i l i 1 l l l l 1 i l i l1 i l 1 t 1 i 11 l i 1 l l l i l l ) I l1 l 1 1 1 1 1 l l l l 1 l l 1 1l l1 i i i i VOUCHER NUMBER CEVQ3-053 DETAIL OF ENTRY Sa l Ir o t p w d HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE i i l 1 ! 1 1 1 1 11 1 ! 1E. . DU POt> IT DE NEMOURS & C OMPANY, INC. EXPERIMENTAL STATION ORDER NUMBER AMOUNT BALANCE i 21597----------- 1 '222 l 1222 i i i i i i i l i i l 1 i 1 l l l i i l 1 1 i 1 i i i l i l l i l i l l i l l l 1 l 1 i l i l l l i i1 1 l i i i i i i i i l i l 1 l i l 1 i 1 l ----------------------i......................... l-- l 1 3 J9I9 i i l l 1 1 1 1 1 1 1 l l i 1 i 1 i 1 1 1 l i l i 1 1 l 1 i 1 i 1 l i 1 l 1 1 1 1 1 1 l l l i l i 1 1 1 1 1 1 l l i l 1 1 1 1 1 1 1 1 1 1 1 1 l - ---------- - 1 DUP050447973 <i ''iN I 'CWMO-KttNKM W n n w fflO U tflnrfC CENTRAL RESEAARrrnCi Himt 8c t it DEVELOPEMENT ib DEPT. LEDGER SHEET *APPROPRIATION * v wA!C"C O*U.1"NT1 j j 3485 j.. CHRONIC INHALATION TOXICITY __ 6671_70 J i_37_ 2929 J STUDIES ON TI02 AND TIC14-CDS.P DATE MONTH YEAR i EES {79 1 1 1 1 1 1 1 1 1 11 1 11 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 11 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 VOUCHER NUMBER DETAIL OF ENTRY BAL SROT FWD CEV92-033 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE 1 1 1 1 11 1 1 1 1 11j E. i. DU POD IT DE NEMOURS 6c COMPANY. INC. EXPERIMENTAL STATION ORDER NUMBER AMOUNT i {24S 1245 ii l i i i ii i i i ii ii i i 1 i 1 l 1i li i 1 i l i l i ) i l i l i l ll i i i l ii l l 1 l 1 l l i l l i i i i i i i i 1 i ili ----_j------------------ BALANCE 2 |452 1 1j 2 {697 l l 1 1 1 1 l l l ii l 1 1 1 1 1 1 1 1 1 1 l 1 ll 1 l ti 1 l 1 l l l l 1 l 1 1 l l 1 i 1 i 1 l l 1 l 1 l l 1 l 1 1 I l ii l 1 1 1i ii1 > :> o in ) .) .) .; n "> ) ) .\ >3' ) ..) } )J \t ) !) .) DUP050447974 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE......................................................................................... ........................ ACCOUANPTPROPRIATION I j 5485^ | CHRONIC INHALATION TOXICITY L_iIlZ<Lj >3_7_2929_J .} STUDIES ON TI02 AND TIC14-CD&P DATE MONTH YEAR JAN 79 VOUCHER NUMBER DETAIL OF ENTRY SAL 8R0T FWD CEVOl-053 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 292 292 BALANCE 160 452 > J *3 <; 'i n i 'wfflrw w j n k iw 4Soow fit r>nicwK 'A) ") J *> E. I. DU PONT DE NEMOURS Be COMPANY. INC. EXPERIMENTAL STATION .; ) T -') ! O ) })) ) DUP050447975 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET ACCOUNT TITLE________________________________________________ CHROMIC INHALATION TOXICITY STUDIES ON TI02 AND TIC14-CQ8.P i 651170j APPROPRIATION i 5485 I m 137 2S29 J > ACC DATE MONTH YEAR DEC 78 VOUCHER NUMBER DETAIL OF ENTRY BAL 8R0T FtfD CEV12-053 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 720 720 bal anc e 440 160 :> hr - > .) ) M' i '.) ) ) ) E. I. DU PONT DE NEMOURS & COMPANY, INC. EXPERIMENTAL STATION ) M ) ) .) ) DUP050447976 CENTRAL RESEARCH 8c DEVELOPEMENT DEPT. LEDGER SHEET 1 ---------------------------------------------------ACCOUNT TITLE_______________ CHRONIC INHALATION TOXICITY APPROPRIATION ACCOUNT i.tw Ti 1i------>547"8..5--'------1---- 1 KR -MJ11Q.J L37_2?29_J STUDIES ON TI02 AND TIC14-CM,Pi DATE MONTH YEAR NOV 78 VOUCHER NUMBER DETAIL OF ENTRY BAL BRO'T FWD CEVll-053 HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 900 900 BALANCE 540 3 3 440 m- HR* E. I. DU PONT DE NEMOURS & COMPANY, INC. EXPERIMENTAL STATION ) t i UK- DUP050447977 CENTRAL RESEARCH & DEVELOPEMENT DEPT. LEDGER SHEET -----------------------------------------------------ACCOUNT TITLE_______________ APPROPRIATION ACCOUNT CHROMIC INHALATION TOXICITY i i 5485 i 667II0] L37.2929J STUDIES ON TI02 AND TIC14-CDR.P MONTH YEAR OCT 78 VOUCHER NUMBER DETAIL OF ENTRY BAL BROT FWD CEV10-053 [HASKELL RESEARCH CURRENT MONTH EXPEND EXPENDS TO DATE ORDER NUMBER AMOUNT 540 540 BALANCE 540 E. I. DU PONT DE NEMOURS & COMPANY, INC. EXPERIMENTAL STATION DUP050447978 Dis t r ib u t io n : s . n . Boyd, Jr. (2) W. H. Darnell (l) J. C. Watts (1) J. L. Riggs (1) R. N. Dion (1) HR- 2929-001 Ha s k e l l Nu mb e r : 11,266 Da t e : 5-31-79 b c m/c f r JGA MM JRB j r g /pw s NAME: Titanium Tetrachloride Sy n o n y ms : None CODE: None No t e b o o k : None -j W *1 (15) INH-LT Sa mp l e Re c 'd : 5-22-79 DUP050447979 N 30812.26 Dis t r ib u t io n : s . u . Boyd, jr. (2) W. H. Darnell (l) J. C. Watts (1) J. L. Riggs (1) R. N. Dion (1) HR- 2929-001 Ha s k e l l Nu mb e r : 11,564 NAME: Titanium Dioxide Da t e : 5-31-79 b c m/c f r JGA MM JRB JRG/PWS Sy n o n y ms : Ti-Pure Co d e : ^one No t e b o o k : ^one (15) IM-LT Sa mpl e Re c 'd : 5-30-79 DUP050447980