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September 20, 1 JVJH^ Dr. Sari W. Doty 900 Pine Avenue Long Beach 13, C lifornla Dear Earl: f I send you herewith, hastily, notations on the composition of the two samples forwarded to us. These formula arc more cr less confidential, I believe, and should not. be advertised, but they do provide seme basis for the beliof that the men may have come to grief through excessive exposure to these materials on their skin and in the air. I know of nothing ve can do further, but If this matter develops further, and we can assist, do not hesitate to call on us. Keep us informed as veil. Thanks. 5incerely yours , T^eber A.' Kehoe, M t)'. EAK ef C.C.: Mr. A. II. Ghonault - with cop:/ of report. Dictated but not read. Enc. Kf 0 U .1, fi 0 -j j Material; Submitted; Required; Two samples of metal cleaning fluids 9-16-52 by Dr. E. Doty for Mr. J. Koehnle, 189 Springside, Walnut Creek, California Identification Kelite, Formula 555 Manufacturer; Kelite Products Inc., Los Angeles, Calif. Uses: Cleaning carburetors Composition; Contains methylene chloride (manufacturer1s information) M .A * C . ; Methylene chloride - 500 p.p.m. Bendlx Metal Clene Manufacturer; Bendlx Products Division, South Bend, Ind. Uses; Degreasing Composition: (Analysis) Chlorinated hydrocarbons (range 1,2 dichloroethane, trichloroethylene) - I'Jp V/ater and soluble solvents Zip Hon volatile resinous materials 12)o Cresylic acid-::- 12-15/-- High boiling aromatics Name given to a mixture of cresols (from coal tar) boiling from 205 upwards. Balance Dichloroethane 75 p.p.m. Trichloroethylene 150 p.p.m. Cresols 5 p.p.m. (California) (a) (a) Boiling range not given, but most likely applies to materials boiling below 205 C. K 001233 0 Reported; ^-lo-^Z N13225.01 ecs Dr. R. A, Kohoe ^ Dr. B. W. Doty Mr. J, F. Koehul Toxicity Investigation S. S. Hinamn Garage Gridley ~ Sacramento, California Sow lork Los Angeles September 19, 1952 Tha following is a brief summary of the investigation of a reported lead poisoning incident. This, covplad with th attached copy of John Koehnle's report, gives the collate (feta of our participation in this investigation. Thursday, August 21st, John Koelmle received a report from Union that had died of a ruptured liver, and that several other KsnworSln^j^his garage were ill. After talking with Dr. Doty and having 1dm talk with Dr. Kehoe, we instructed John Koehnle to mice an investigation on Friday, August 22nd* and report to us. Th original report mentioned that competition bad first been called in and had told Union Oil Company, who delivered gasoline to th garage, to turn it over to us, since we furnished lead to Union in that area. The original Information indicated that the death sight have been caused from lead poisoning, Gn Monday, August 25th, Ik*. Doty and I met John Koehnle in Sacramento and mads an investigation at Gridley. Dr. Doty handled th medical in vestigation with the local doctors, and X looked over the garage. We met Dr. Carry - who took cars of John Parry? Dr. Bartsehi - who was taking care of Hoyd Blgerstaff, J. L. Brothers, E. A. Bears and J, Ennisj and Dr. Marphy, Countb Health Officer for But County - offices la Chino, Wo took load analyses at th garage and found two samples gav an absolute aero reading. This information, coupled with other data, Indicated to us that lead was in no way involved. After leaving Grldley, and discussing the subject with Sr. Doty he was of th opinion that th causa of th death and the illness of the other toon whose symptoms were exactly the same as Mr.^pPPwho died, indicated that it night be hydraearbon poisoning* On Dr, Doty's return to Dos Angelas he discussed tha subject with Dr. Rutherford Johnstone, a Toxicologist in los Angeles, and with Dr, Kehoe. With what information that was available, they felt that it might be chlorinated hydraearbon poison* lag. 0012331 N13225.02 I,tr* to B. t. S&faty, Coat'd* Toxicity Investigation -2- Septesfcer 19, 1952 frm John Xoehnle *s original investigation we found that they had boon using Bendix "I-fetal 01006", and "Eelite Formula 555** for cleaning carburetor and fuel pump parts* Before our visit to Sacramento, Ur* Doty and 2 were able to obtain rather couplete information oa tbs composition on the ttKlitett, which was chlorinated solvents plus detergents which were sulphurn&tsd hydracarbons plus other ingredients* Br* Doty will undoubtedly cover a couplet analysis in his report* y were unable to learn tbs chemical analysis of the Bendlx cleaner* On my visit I found that the Bendiz cleaner had been used for quite a number of months, and was almost "spent" Therefor, they had bought "Kellt" to take its place* The Bendis cleaner had been used to about July 15th, and the "Kelite" was started to be used somewhere about July 1st* On John Koehnle's investigation he found that both five gallon earn of cleaner were open sitting in the garage. The Bendix cleaner was sitting next to the heating and ventilating system, and the "ellttl was sitting next to the carburetor work bench. Their heating and ventilating system consisted of a rather large blower in one side of the garage, which picks air up at about three feet off of the floor of the garage, and circulates it through a duet system over head that blows directly down where the rasa work* This air is heat ing in the winter time, and circulated in the summer time for cooling. After leaving Gridley, and discussing the possibility of hydra<mrbon poisoning with Dr* Doty - I suggested that the Mating system would be a perfect distribution system for hydrocarbon vapors, however, we did not determine any source from which the vapors could have com* It is signifi cant that the stock man ia also showing symptoms and. at m time works out in the . garage in cleaning parts- or mopping floor's'and such* Upon receipt of a negative answer from Bxvlfoiy's blood and urine samples, the Sales Department will discontinue further work on tbs project* We feel that in this invsatigatloa we have boon of definite service to our customer, the IMoa Oil Conpacy, where competition pulled out* ;:.^..'taosf9 very truly, ABCsdo. Attach* September 17, 1952 P, S, Dr* Doty has receive;' negative reports of lead In blood and urine samples taken from Bigerstaff and Brothers (no other samples taken). He will report to Dr. Bartschl, which will lose our part in this invest!- ertto"'- - KE 0012332 - \ 1' i vV a; *'*f< '1 , ^j ^ ^ '* '' ,'y' ' ^1 \\; \,; ;v . ^ %9MbKU(. / ""W*: w Ai > i ,...... ./:t,..... .i<t.',f..M... *'- ;VV ftwrocteaC fQi I'ol&ohiag Css*' aridity* fiWUf* * TMon Oil On. ` * * ' , 'O*. o * * ,v -AJ L> >' > (1 ' ' Gs Agt tlrmoa'Oil Go * 4a- ' \`> ra '' s, > V* ^a PzmqlfM v -i J - *" M* 5,>?5? i, > , 3 tt r t <*' w - (*/ ' 1v f nofeiftal ^t^rl -4 * -vsy.`. * 's `4vtS t" . ...,,: 4. ( vp/ / 4^^ in tod airship, .15, i . >t. >'.' 'e&mv*..'........ -........................t... ! . ./, < --l- .V ; . - ,r Xt was learned ceaspstltlod, had haon notifiOd first tyo 2& > , haforo end/had S*M*ttaML1to' caarat fbm~waam *1$*. XMoa011 ; - .......; .^ ....."..* ,\. 1 s ^},- 'l\r ` 'f*'J \ tw th < OyerAUos ^^aoa^r^fcoard' of Sk> tliye4,,1^31114 /' } . .. ... oai..ef.,.^,.oae^ ^n. .. - ot or bocsus Vatr^Uc^ tho fluid. Both etbrlo haw heea roported, Xu ay'W v tooidad to Snbldfut aud ^ 1'ri^' &g&st' 2^t & trip w# m# to Ojptaioy &ts oil p&rtaoa oxesT't -tho ; Ifelow W& of tli , v>\ 1 f\Mfi ?it..,.*.. ...... ^ itPH ..O..u. .A.,,.w..r.a..^..t- i 4;4^H1HhI,4 a r^eGachhaaatiiieo aatt tth^o'lllllnteosaimu .ttoorril..-'...y,..x,'.'.',>i',.t -' SoalorsMp, 'dial ium^ of approxtetcjly fiss ' ls41o&tiou! ' '':> cesiofiMi Wiii W' '.' * - V vl>> ' V 4 ^' 'j-ifrV. y" ^ ^- * V< is ' had'-Ah': 5 i - > ^ ^ 4w wport ou* V.-* ext^dtioo^ ((^ms patlOiiMms ttoa i^safafe in ,Ua4sd OCBRl^to t^fe' Tifealtiw ttndit km \ thn 2feikfc* 4 a i;i' ,, \ . *. " *W N13225.03 *** >* pleased ftw the hospital last Jridsy or i&tor&gr in. a* seaSitio*** ixJ'l.,/f .',%..... ` ..x i ,i, wilca! report m&C nr felloe* - H1bs|twXar eruption / rMila, lco tender ovor liver, Thin H the third one fire omrtoyar < t '1 .r ' -1 "-'V'? f, pr, rr. Ocrey the local jfcyoXcien* Our Dr* icty wo ilS.e4 by ; ,, -- ifijacnatat ani conculied t&th $r -Carey* f3a Penney, &k&s& 3 r, t)cvty J:;|| tfcastp ^rittUy and ae&i cas'ott-tJ^s^rs essa&nrticm, fic*, lift? te&^ui&at' '`f>fv; J^efedls of this Dr* Ibty sjlli Jews to be consul fe\'/ ' " ' . : ; . ,,.* a ", . `\ !' J: .'coordin^ to informtloft received ot Oridtoy Iflbo-follcyla#; am ' dcMis of the factors aMcfr'jr.sy be n snaroc of tiSc problem, , '. ' * ' 1 f\ * for sqy. yoarsr.this Vord dealership fcjy* 'boon 'eir^ Imtiwl gimltm .-.. ..> . for clcorda; the floor And wohing vert**.. Ap- roxl&ately 300 Xlwan djmit \ are '"rod on the .floor ylue probsMy helling. meh used for*detain4; f^rts* "About &,.* quart of rGprrvfinea oil added to roll gallon of /? soli no used for eleraiijr; parts; Sstrmd viva halls vem used fcp aboevb the f/ noting on ths floor sr.! to idcl iH(clorni7j;* *2wo k b tel chmicrd ole^ro have l&en. veal by this : lalita ' Foictula. ^55 sum hsndix Jfefcalclfta, Samples, of fmm cheepers obtained and /sr.t to Ur, Kchoe la Olncir&ati for hie analysis*. " (i -r'y .' ; S,' ;; `/\'ph-A-v!-'--v. /; !. C *.'% .' - ;.;/'. '; ' ?/': -} '- . / h,:' '-'.-'' ; .'. i`' :. , ' ',.}y. io.-r. . h.'Jf 'v/ ',`:;'.^fv ;^H,' .. ? :!. ; ' ' ' h'h' f.' ;'"/CV.- "vV-d-iv*.jf';' / '. , - 1 , . ..... -v.:- -' '!-;h'. fiy >/'1 ; V ; .. yimw Qmv-xilt di^covorod oho harrrtdnt factorf or risp-ai duct '' ';'; ^yst^ i.- coih*ctsl to a fiancee looted XusIOa alie Luiiric^ with its air Intake near tlic fleer* ; Xa jmr &i wMtp istumd to circulate tiio air > S , inside the tmildin^, In vintsr ah oil heater famic*e4 le&t to lie `, , t;,eeA bcs-tc tlic , A? Same pointed out, this vo4>d bo # vcnr^rfal air ' * dlfdril&it'-y If say Vs$t v plolsd tlo blover* ^ ^ 1S#q lea3r%ssir tents v$m asds in tlsg ^rrr^, A yaaUin^ of 0 (zero) ' %s.obtained* Tr ' ^, ' ' -*< ^ -i '* * ' h i'ho- use of clourshbn 1?on dlgcpntlhasd* 1. ? V/ 'V'"-* pfiVlil'i1 pC1a/S1*, i,rnr fena j%^Jtwii*cn/'instiS's/'oA ^ J sa mrto*j?* ort tM's?V '4 iH ^ ',V> /;. ' , i -.- ,; ,' r ': ' 'V:-, ,; */ &-V ' * >{ ?r; ... 'J:> : K 'Vwiizm rt > V - ` h ; *' " w/ - ;s-; N^ ^* A Required: 13, California Lead Analyses URINE analysis Number Volume Specific Gravity Mg. Pb/Liter 52A-5612 118 ml. 1.027 0.09 BLOOD Analysis Number Weight 52A-5613 19.6 Grams Mg. Pb/lOO Grams O.Op (Spectrographic) Mg. Pb/lOO Grams O.Olj. (Dithizone) The concentration of lead in the blood is within normal limits. The ur-inary lead concentration is also within the normal range for a sample of this volume. `The combined results demonstrate that this man has had no recent occupational exposure of any consequence to lead. Signed: Robert 'A. Kb hod , M. 'TT. Samples Collected: 8-2p-52 Samples Received: 8-29-52 Samples Reported: 9~k-52 RE 0U^ 4 r* 6 r\ * - 0J0 N13225.04 Material: Submitted: Required: Urine and Blood 8-29-52 by Dr. E. Coty, 900 Pine Avenue, Long Beach 13, California Lead Analyses A / U -Rr-ImNm.E- Analysis Number - 52A-5610 V Volume ,, - 8lp ml. Specific Gravity - 1.030 Mg. Pb/Liter - 0.10 BLOOD Analysis Number Grams Mg. Pb/lOO Grams - 52A-5611 Spectrographic Dithizone 15.0 19.6 O.Oij. 0.03 The concentration of lead in the blood is well within normal limits. The urinary lead'concentration is also within the normal range for a sample of this volume. The combined results demonstrate that this man has had no recent occupational exposure of any consequence to lead. Signed: Robert A. Kehde, D. Samples Collected: Samples Rece'ived: Samples Reported: 8-25-52 8-29-52 9"^4-"52 K 0012830 N13225.05 DRS. ST'EEC&jg, SCHRDEDER & LEE 1019 AVALON BOULEVARD WILMINGTON. CALIF. August 29, 1952 90 12 ma t c c iic e r n : These :een are the employees of the 3. S. Uinenan Garage, in Cridlcy, California, in mhon there mas sene question of TEL ii'toi'ication: industrial medical History: This mar first began working at the 3. 3, Fireman garage in 19ql. Since teat tine, he lias done all types of mork around the garage, but he has worked primarily in the mechanical Department and in the Service Station, Many tines, while in the Mechanical Departnent, ho has dipped automotive parts in five-gallon backets of gasoline, but as to the enact number of tires--daily or meekly--it is difficult to ascertain: however, lie does state that on occasion, ivher. ho has dipped his hands in the gasoline, his hands have become numb from the mixture. (Note: This rirture is apparently not *-- gasoline, but contains tno and one-half gallons of Union Oil y76 gasoline, plus -approminately one quart of lubricating or drainage oil,) On occasion, lie has also dipped automotive parts in a solution, of Kelite, but this has been rare. Past History:: This patient had the usual childhood diseases. In April of this year, he had an operation for correction of Strabismus of his right eye. This apparently mas a congenital abnormality. He pras rejected from the United States Army because of this eye and because of rather marked Pes Planus, Present illness: On or about August 15, 19^2, the patient merit to bed feeling quite mell, but during the night he mas amakened by an intense burning and itching of his hands. He noticed that his fingers contained numerous rather large bullae; these mere apparently primarily on the dorsum of the fingers. Ey the following morning, he also noticed K ET 0012 *3 3 'i N13225.06 Pace three his hands and the soles of his feet. He had no other symptoms of any kind--no headache, no frequency of urination, no pain in his extremities, no constipation, no diarrhea. Past History: The patient had the usual childhood diseases without any serious illness of any kind. He has also had some constipation, but he has frequently been told by his doctor that this was due to "pure laziness11, During the time he was in the army, he suffered Injury to his ear, but otherwise he has had no injuries or serious illnes deamination:: nomination of this patient was negative except for the presence of rather snail vesicles around the tips of the fingers, pains of the hands, and soles of the feet. These vesicles were very small. There was no evidence of any bullae--past or present. Tbcamination of the abdomen revealed the liver margii to be alpable and tender. 3xanination was otherwise negative. age 25 Industrial medical History: This man has worked for the S. S. Hinoman garage since 19h9* He has also worked in the Parts Department, At the present time, he calls himself the"12anager of the Parts Department" He 'nas only dipped his hands in the oil mixture,or the Bendix.solution, or the Kelite, on rare occasions when he has been out to the Hechanical Department to inspect a broken part. In fact, he very infrequently lias any contact directly with any of these solutions. Very thorough questioning of this man revealed that, to the best of his knowledge, he had done nothing unusual, either in ids work or at hone. Present illness: This man also began having small blisters on his hands and feet approximately one week ago. He describes those areas as itelling severely and then, before he was aware of the fact, the small blisters began to appear. The itching was most intense, especially in the areas where lie perspired a great deal. He did not develop any bullae. Past History: This man had the usual childhood diseases. He has been 0012838 Page four in good health, except for the fact that he has had some hay fever which has never been disabling in any tray* He has never had ary history of allergies. Examination: wcanination revealed some small vesicles around the tips of the fingers, the palms of the hands, and the soles of the feet. The liver margin was palpable and tender. There mere no other abnormal physical findings. C onnent; It was the usual custom, in this garage, to Trash up the floor nightly with Union Oil #76 gasoline. This was done by putting gasoline on the soiled areas and -where there was excessive grease,' . putting rice hulls on, then sweeping up the mixture. Hone of the men mentioned, have ever had anything to do with, this cleaning-up job; the man who docs this is, to the best of my knowledge, in good health at the present tine, lir. brothers told me that many times as he has opened cans of Kelite, he has noticed a strong smell of the fumes, but this has lasted only a few seconds. The automotive parts were apparently cleaned by putting them into a basket and then dipping the basket in either the Kelite or the Bendix solution. The basket was then taken out of the cleaner and carried away and washed with a hose. I did not look at the working environment myself, but this was thoroughly checked by Hr. Chenault and Koehnle, of the Ethyl Safety kepartuent, The report will be forthcoming from ir.Chenault. EVfl) :IcK tr-X- u. d-PC m.ix 6Earl >*'. JJoty, L-1.D, 900 Pine Avenue Long Beach 13, California 0013339