Document yjkjx2LOxwqjpOvv4E78NEk6

I A ugust 3, 1972 Dr. A lfred W eissle r, A cting D ire c to r D iv isio n of C o lo rs and C osm etics Technology O ffic e of P ro d u ct Technology c Food, and Drug A d m in is tr a tio n D epartm ent of H e a lth , E d u catio n and W elfare W ashington, D. C. 20204 D ear Dr. W eissler _-- E n c lo se d p l e a s e f i n d my f i n a l a n a l y t i c a l r e s u l t s on t h e m in eral com positions of 102 exam ples of sta n d a rd , com m ercial p ro d u cts c o n ta in in g ta lc . These include a l l th e specim ens you s e n t me from W a sh in g to n , e x c e p t f o r a few ( p r i n c i p a l l y S he p h arm aceu tical specim ens) w hich I w ill re p o rt on s e p a r a te ly , as w e l l a s a number- t h a t I p u r c h a s e d i n New York and i n B o s to n . The a n a ly s e s show t h a t 59 o f th e p ro d u c ts have no d e te c ta b le am ounts of any of th e a sb e stifo rm m in e ra ls (by th e tech n iq u e em ployed, p rp p o rtio n s by w eight of 1-2$ o r le s s could' e sc a p e d e t e c t i o n ) , 20 had s m a ll b u t d e f i n i t e p e rc e n ta g e s o f tre m o lite , 7 had sm all p e rc e n ta g e s of c h ry s o tile , 9 had sm all p ercen tag es of b o th tre m o lite and c h ry s o tile , and 7 had sub s ta n tia l p ercen tag es of one or both of th ese asb estifo rm m in e ra ls, I s h a ll r e t a in and p re s e rv e th e o rig in a l specim ens, and th e x - r a y d i f f r a c t o g r a m s , u n t i l y o u a d v is e me o t h e r w i s e . W ith v e ry b e s t p e rs o n a l re g a rd s , S incerely yours, Seymour x . new in P ro fesso r of C hem istry PLAINTIFFS EXHIBIT C A M -153 TABULATION OF X-RAY DIFFRACTION ANALYSES OF COMMERCIAL PRODUCTS CONTAINING TALC ______ A. P ro d u c ts h av in g no d e te c ta b le amounts o f a s b e s tifo rm m in e ra ls ( l i m i t o f d e t e c t a b i l i t y = o a . 1 t o 2$ f o r e a c h m in e r a l) Product M ineral C om position Talc C h lo rite P h lo g o o ite cX-Quarts D olom ite O th er 1 2 70$ 100$ 3$ n .d . 3 4 19090$ $ n .d . n .d . 65 8905$$ 2$ 2$ 87 86$ 95$ 27$$ 109 11 89$ 7$ 93$ 90$ 32$$ 12 130$ n . cl * 13 60$ n . d . 14 1165 13010$$ ---- 50$ n .d . ---- 1187 60$ 30$ 90$ 4$ 1209 21 97$ 35$ 67$ 160$$ 25$ 22 59$ 35$ 23 24 42$ 50$ 94$ 1$ 25 95$ 2$ 26 27 28 29 8958$$ 1$ n .d . 20$ 94$ 21$$ 30 97$ ' 1$ 7$ n .d . 1$ n .d . 3$ 25$$ 32$$ 2$ 2$ n.d . n .d . 2$ n .d . ... 4$ 2$ 2$ 1$ 2$ 12$$ 2$ 3$ 4$ Oaf n .d . 2% 2$ n .d . n .d . n .d . n .d . n .d . n .d . 3$ n .d . 2$ 2$ 4$ n .d . n .d . 10$ n .d . n .d . 2$ n .d . 4$ 3$ n .d . 3$ 3$ ' n .d . n .d . n .d . n .d . n .d . n .d . n .d . n .d . n .d . n .d . n .d . n .d . 2$ n .d . n .d . cnO~C/.o4d . n .d . n .d . 7$ Ha d. -- 6$ 2$ \ n .d . n .d . 3$ 5$ 3$ n .d . n .d . n .d . 19$ n .d . 2$ n .d . ZnO ZnUd ZnUd .K, t S CaCO^ 1 Product 31 32 33 34 35 36 3387 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 T alo w80/a 55% 78% - 78$ 79% 38$ 87% 94$ 66% 81% 89% $6% n .d . 65$ 48$ 100$ 88$ 100$ 19050$ $ 85$ 90% 90% 78% 86% 79% 96% 90% P pre 2 C h lo rite 50T " 7% 40$ 7% 5% 4$ 50$ 5% 3$ 28$5 $ 6$ n .d . n .d . 30$ 40$ n .d . 4$ n .d . 5% n .d . 8$ 4$ 3$_, 15$ 7% 15$ n .d . n .d . M inerai Com position Phlotfoplte k -Q u artz 3$ 32$$ 2% n.d 4$ 2$ 130$ ^$ 2% 15$ 5% 4$ n .d . 2$ n .d , 3$ }% 4$ 2$ . 1$ n .d , 1% n .d . n .d , 2$ n .d , n .d . n .d . 3$ 2$ l# .a 3$ n .d . n .d . 5$ n .d . 2$ n .d . n.d . n .d . 4$ 2$ 3$ 2$ 2% 1% n .d . 32$$ n .d . 5$ 3$ n .d . 4$ ' n .d , 3$ Doloral t e 8$ 8$ 3$ 8$ 5$ Ja, d. 7$ C /O n .d , 5$ 35%i n.d, n.d , 4$ 7% nd. 4$ n.d , n.d , n .d , n .d . 2$ 4$ n, d 2% 5$ n .d . n .d . O ther ZnO, K S B. P r o d u c t s h a v i n g staa.ll a m o u n t s of T r e m o l l t e -- m o r e t h a n 1%\ . but not more than ($2)% by weight P ro d u c t M in eral Com position T alc C h lo rite P h io gonite fc<-Quart i 60 61^ 3% n .d , n .d . 61 35% bof> 62 89% 2% 63 87% 2% 8h% 5% 65 79% 15% 66 85% 5% 6678 75% 15% 78% 15% 69 96% 1% 2% 3% 1% 3% 2%.: k% 3% c 2% n .d . n .d . 3% 1% n .d . n .d . n .d . n .d . 1% n . d . 70 26% 6 0% n .d * ~5% 71 8A% 10% 72 86% 5% n .d . 3% 3% k% 73 79% 10% 7^ 92% n . d . 75 75% 5% 1% Tid 2% 3% n .d . n.d* 76 75% n . d . 5% 5% 77 91% n . d . 78 79 8856%% 2% 5% b% 1% 2% k% nd* D olom ite Trem oli te 7% 18% n .d , n .d . 3% b% 2% 5% 5% n .d . 7% n .d . n .d , 5% 5% 15% 10% n .d . 3% 2% 2% 2% 5% 5% 3% 2% 5% k-% 2% 2% 2% 3% 2% 2% 3% 3% 5% 3% 5% 3% v- C. P ro d u c ts having s n a il am ounts o f C hrys& tile b u t n o t more th a n (5*2)% by w e ig h t. snore t h a n 1%, P ro d u c t M ineral C om position Pale C hlorite Phlog c p ite -Q uartz D olom ite C h ry so tile 80 k8% ko% 81 82 80% 76% 17%2% 83 81% 6% 8^ 87% k% 8865 83% 5% 82% U% n*d. 1% JCE-'Pe/0r I/O 2% CO/aof 8$ 6% n .d . n .d . n .d . " k% n .d . b% 3% 3% 8% K% h% 2% O/o 2% k% t'D, P r o d u c t s h a v i n g s m a l l a m o u n t s of b o t h T r e m o l i t e a n d Q h r y s o t i l e ~ ~ 5 27m o r e t h a n 1%, b u t n o t m o r e t h a n ( * $ of e a c h b y w e i g h t . Product M ineral C om position T alc C h lo rite P h lo g o p ite c(-Q uartz D olom ite T re m o lite C hrysotlle 87 28$ 50% 88 6 l$ n, d. 89 68% I/O 90 55% n .d . 91 28% 1% 92 6l% n . d . 93 55% 1% 9^ ^3% k% 95 8 7 $ n d n .d . n .d . 3% 3% 3% 4$ 3% n ,d . k% 5% 8% 7% 69% 6% 6% 6% _ 5% 12% 2 5% 10% 25% 3% 20% 25% }$% b% h% iv% 5% 5% k% 5% 5% A* 2% 2% 5% 5% 5% 5% 5% 5% 2%  P r o d u c ts h a v in g s u b s t a n t i a l a m o u n ts o f C h r y s o t i l e a n d / o r T B e m o lite ~~ mor e ^ h T T 5 ^2 )% by w e i g h t. P ro d u c t M ineral C om position T alc C h lo rite F h lo g o p ite c t-Q u arts' D olom ite T rem o lite C h ry so til 96 66% n . d . 97 31/ I/o*i o f 98 39/ n . d . 99 3/0 100 78$ 7/o 101 102 53/ 8^ 65^ n .d . 3% 1/ 3# 3# h% 3% n .d . 6% 5% hoi ho% n .d . 7% 3% 7% 00/c0f 35% 12 % 6% 2% 6% 3% 3% h% 25% 15% 10% 10% 15% 10% 8% 6% n .d . 7% t r Pdqe 4 NOTES TO THE TABULATED DATA 1 , A ll pro d u cts te s te d w ere standard and com m ercial b ra n d s, purchased in drug sto re s or th e drug departm ents of departm ent s t o r e d o r s u p e r - m a r k e ts i n t h e c i t i e s o f W a s h in g to n , D. C ., New York, and B oston. 2* A ll d a ta a re b a sed upon co n tin u o u s sc a n x - r a y pow der d if f r a c tio n p a tte rn s . The p re c is io n , in term s of av erag e d e v ia t i o n , i s o f th e o rd e r o f m a g n itu d e of 2% a b s o lu te f o r each o f th e m in eral sp e c ie s rep o rte d * The d a ta a re g iv en in u n its o f p e r centage com position by w e ig h t. 3* The l i m i t s o f d e t e c t a b i l i t y by th e m ethod em ployed a r e o f t h e o r d e r o f m a g n itu d e o f 1 t o 2% by w e ig h t f o r e a c h o f t h e m ineral species c ite d , ; - ' 4 , A. Where an a s b e s t i f c r a m in e ra l was in d ic a te d by th e x - r a y p a tte rn as being p re se n t to a d e fin ite ly d e te c ta b le e x te n t, i t s p re se n c e was v e r if ie d by th e u se of o p tic a l m icro sco p y to d i s c lo s e th e p resen ce of s i g n i f i c a n t numbers of f i b e r p a r t i c l e s . B. Where th e a c b e s tlf o r m m in e ra l was in d ic a te d by th e x - r a y p a tte rn as being p re se n t a t th e ju s t b arely d e te c ta b le le v e l, \ t h is was v e r if ie d (o r r e je c te d ) by employing th e s te p - s c a n te c h - . nique over the reg io n s of th e q u estio n ab le d if f r a c tio n peaks, 5* The f o l lo w in g m i n e r a l s w e re e s tim a te d b y c o m p a rin g t h e sum o f th e in te g r a te d i n t e n s i t i e s a t th e d i f f r a c t i o n a n g le s l i s t e d b e lo w , w ith t h e c o r r e s p o n d i n g summed i n t e g r a t e d i n t e n s i t i e s a t th e same a n g le s o f s ta n d a rd s composed o f th e p u re m in e ra l M ineral D olom ite (^-Quarts C hlorite P hlogopite T w o-T heta V a lu e s ' Summed 31,0 - 31. 2} 44.8 -4 5 .0 .; 2 0 . 4 - 2 0 , 6 j 2 6 ,6 - 2 7 * 0 } "s-3-9*3-39*71 6 , 3 - 6 . 5s 1 2 .4 - 1 2 ,8 ; 1 9 ,0 - 1 9 ,2 - k 2 5 .0 - 2 5 .4 8 .6 -9 .0 } 2 5 ,9 -2 6 .1 ; 2 8 .1 -2.8.3V 6* Only two o f th e a s b e s tif o r m m in e ra ls w ere d e te c te d i n th e p ro d u c ts te s te d . Each o f th e s e was e stim a te d by com parison., w ith s ta n d a rd s made up by f i x i n g th e p u re m in e ra l .w ith p u re t a l c in v ario u s p ro p o rtio n s by w eig h t. For both unknowns and sta n d a rd s, th e param eter measured was th e r a tio of th e in te g ra te d in te n s ity o f a d iffra c tio n peak, r e la tiv e to th a t of an in te r n a l standard* The i n t e r n a l s t a n d a r d em ployed was 5% by w e ig h t o f 2 n (O H )C l, The i n t e g r a t e d i n t e n s i t i e s w e re summed a t t h e f o l l o w i n g d i f f r a c t i o n angles j ` ' V V\ A sbestiform M ineral T w o-T heta V a lu e s Summed VK C hrysotlle T rem olite 12.0 - 1 2 ,4 ; 24.3-24.8 10.4 - 10,6} 27,4-2?,6; 29,4-29,7; 3 0 .6-30.9 33.2-33*4 .' \% Pdfyt 7 T alc was d eterm in ed by d if f e r e n c e . The fo llo w in g a b b r e v ia tio n s a re employed j n , d* * n o t d e t e o t a b l e ZLhO - z in c o x id e ZhU rf- zin c xm deeylenate K kao lin 5 starch aCX= o a lc -ite X = phase n o t id e n tifie d unim portant. because deemed I n s e v e r a l I n s ta n c e s , th e same bran d o f p ro d u o t was p u r chased in d iffe re n t p laces a t d iffe re n t tim es, to check on th e constancy of com position o f th e m ineral n lz tu re . C o n sid erab le v a r i a t i o n s w ere fo u n d . S ee p ro d u c t num bers lb and 15? 2 2 , 22 a n d 23j ^ <" n >b t h e r i n s t a n c e s , c o n s ta n c y w i t h i n t h e p r e c i s i o n o f th e a n a ly tic a l method was o b serv ed ( e ,g * # in th e c a se o f p ro d u c t Uo, 7 ) . !l ! J KEY TO PRODUCT NAMES P ro d u c t Number P r o d u c t Name 1 AMMENS POWDER, MEDICATED 2 AMOLIN DEODORANT POWDER 3 AQUAMARINE COOLING SPRAY BATH POWDER 4 BAGATELLE AMBER DUSTING POWDER BOURJOIS BATH POWDER CALDESENE MEDICATED POWDER 7 CASHMERE BOUQUET BODY POWDER 8 CHANEL NO. 5 BATH POWDER $ COUNTESS ROCHEAU CAKE DUSTING '' . POWDER 10 CREPE DE CHINE DUSTING POWDER, MILLOT 11 CREPE DE CHINE POUDRE MIST, MILLOT 12 CUT!CURA TALCUM POWDER 13 DESENEX 14 ; DESITIN BipY POWDER 1165 DESITIN BABY POWDER DIAPARENE BABY POWDER 17 DOROTHY GRAY "SECRET OF THE SEA i DUSTING POWDER 18 EMEBAUDE TALCUM POWDER 19 ENGLISH LEATHER 20 FABERGE *'piBIC DUSTING POWDER 21 i FRIENDSHIP GARDEN DUSTING POWDER 22 FRIENDSHIP GARDEN DUSTING POWDER 23 . FRIENDSHIP GARDEN DUSTING POWDER 24 HEAVEN SENT AEROSOL BATH POWDER i MIST 25 HEAVEN SENT BATH POWDER 26 HELEN PRESSL "LITTLE LADY" \ IMPORTA, SPAIN MENS* TALC m 1 IS IS FLORAL TALCUMPOWDER 29 { JOHNSON'S BABY POWDER 10 I JOHNSON AND JOHNSON MEDICATED. I PBWDEB 31 KOSCOT BEAUTY DUST-- OIL OF MINK 32 | LANVIN ARPSGE DUSTING POWDER 33 f LANVIN ARPEGE ROWEEHED MIST | LANVIN ARPEGE TALC 35 f LEWIS BABY POWDER 35 * LOVES FRESH LEMON C-LOSSY POWDER 37 { MACY*S SCENTED BORATED TALCUM o I MACY'S TALCUM, APPLE 39 ! T-1ARCELLE DUSTING POWDER, HYPO S' ALLERGENIC 40 MARY CHESS PERFUMED DUSTING POWDER . F urther Id e n tific a tio n B risto l-M y e rs (No. IF25) N o rw ich Revlon (143) C orand (DCH) Pennw alt (5274) ; C o lsa te -P a lm o llT ^ g lim Jergens House o f F ra g ran c e (L1132' House o f F ra g ran c e Purex (07170) W TS-Pharm acraft P fiz e r (1139Z) (3 /2 9 /7 2 ) P f iz e r (115A) (5 /1 0 /7 2 ) B re o n (ElOgLO) Coty (355-4010) Mem (2891) Shulton (3/27/72) Shulton (5 /9 /7 2 ) Shulton (7/13/72) R ubinstein R ubinstein (028Q) <3612) (1288) Manley & Jam es (2K4) a -ro d u c t Number 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 yro cm cc Name F urther Id e n tific a tio n HENMEN BABY MAGIC POWDER (B112) HENHEN QUINSANA FOOT POWDER (H202) MERCK TALC, PRODUCT NO. 6460 LOT ! NO, 6460) (8039301) HEXSANA 2387-D MEDICATED POWDER P lo u g h OLD SPICE BODY TALCUM S h u lto n PERSIAN LILAC DELUXE DUSTING < i POWDER A p r il Show ers (LFN) PERSIAN LILAC SPRAY BATH POWDER A p r i l S how ers (B200B) POND' S PERFUMED TALC BODY DEODORANT DREAM FLOWER (115B) PRINCE MATCHABELLI BELOVED SPREY J POWDER QUEST DEODORANT POWDER REPLIQUE SPRAY BATH POWDER Parfum s R aphael (004) BIVIAMA FOODS - ITALIAN STEARIN TALC F o r R ic e SEPTEMBER KORN BY POND'S (19B) SEVEN WINDS AFTER BATH TALC U S P TALC DuBarry (021035) YASELINE INTENSIVE CARE BABY PONDER (I 209) IVES SAINT LAURENT RIVE GAUCHE SPRAY TALC I B T BABY PONDER (1021) ZEASORB SUPER ABSORBENT MEDICATED POWDER S tie fe l 60 AMBUSH-DANA DUSTING POWDER 61 APRIL-SHOWERS 62 AVON UNFORGETTABLE PERFUMED TALC (9884) 63 BELOVED PERFUMED DUSTING POWDER, PRINCE MATCHABELLI 64 COTY FACE POWDER RACHEL 65 DESERT FLOWER SPRAY BATH POWDER S h u lto n (F 1 BKI) 66 EKERAUDE DUSTING POWDER C o ty 67 EHERAUDS SPRAY DUSTING POWDER C o ty (1 AEY) - 68 PA3ERGE FLAMBEAU D?.'ODORANT SPRAY POWDER (3 7 WBF) 69 JEAN HATE SPRAY BATH POWDER ( I N 247) 70 JEM'S TALC, FLESH 71 jfCLIE MADAME DUSTING POWDER, BALMAIN 72 LADY ESTHER FACE POWDER, RACHEL ' 1`iAX FACTOR FACE POWDER, RACHELLE U INDICATED COMFORT POWDER Parke-D avls 75 OHI d e LONDON TALC ' Y ardley (493) 76 TO KNOW ME IS TO LOVE ME - TINKERSELL ?om F i e l d s , L td , 77 TOUCH AND GLOW FACE POWDER, CREAMY PEACH R evlon 78 TOUJOURS KOI BATH POWDER C orday 79 YARDLSY APRIL VIOLETS ' : (4908) 80 CHANTILLY DUSTING POWDER i H oubigant 51 .CASHMERE BOUQUET 82 JE M NATE TALC 83 HENNEN SHAVE TALC . ' (B 8 1 ) 84 SHOWER TO SHOWER ED'DY POWDER Jo h n so n & Jo h n so n "(5507BG) 85 PURE BABY POWDER-, DART DRUG 86 ROND' S-DREAM FLOWER PERFUMED TALC (K .1 1 C ) (0 13D) i 'r T* Pa^e )' ; r P ro d u c t Number 8? 88 89 90 91 92 93 94 95 P r o d u c t Name F u rther Id e n tific a tio n ALKAX HYPO-ALLERGENIC FACE POWDER CONSTANCE CARROLL, BOUQUET TALC DJER-ICISS TALCUM FLAMINGO DUSTING POWDER, TUSSY LANDER LILACS AND ROSES TALC MAVIS TALCUM MAVIS BODY POWDER TANGEE c ZBT BABY PONDER K erkoff (L I047) V ivaudou V iv a u d o u L uft-T angee (B0048) 96 BLANCHARD'S DUSTING POWDER 97 BORN WILD DUSTING POWDER Del Labs 98 LANDER GARDENIA AND SWEET PEA TALC 99 LANDER LILACS AND ROSES DEODORANT BODY TALC 100 KISS DIOR DUSTING POWDER 101 TAI WINDS SPRAY TALC (Avon (DCC 1272 2 - 1 4 - 7 2 , HWS) 102 TOSCA DUSTING POWDER