Document ybQyL6m1krvENykXYD4aXRm7E

ACT tal ral* ening (8%f 19%) 46%) 38%) 19%) 'ration of OSURE lit ides (4%) (8%) 19%) 12%) (8%) ition of s BY More mality 24%) 36%) 60%) 53%) 35%) ificantly Anderson et alHousehold Asbestosis 395 Table 11 Prevalence of Radiographic Abnormalities by Year of Onset of Exposure* Year of Onset of Exposure ' 1941-1946 1946-1950 1950-1955 Total Examined 434 113 129 Small Opacities 79(18%) 19(17%) 16(12%) Pleuralf Thickening 98 (23%) 21 (19%) 9 (7%) Pleuralf Calcification 46(11%) 5 (4%) 3 (2%) One or moref Abnormalities 172 (40%) 38 (34%) 29 (22%) Total 676* 114(17%) 128 (19%) 54 (8%) 239 (35%) Three individuals with uncertain year of onset excluded. tPrevalence of abnormality greater among those with earlier onset of exposure, (p < .01). for the pleural abnormalities. Statistical significance was not reached for a similar increase in combined small opacities. The relationship of the household contact to the worker was also important (Table 12). Wives had the highest prevalence of abnormalities (48%) and daughters had the lowest (21%). Mean duration of exposure was the same for all relationship categories. The prevalence of abnormalities was statistically significantly lower among the daughters when compared to the other exposure groups. With only a few exceptions, household contact clinic participants were unaware that they had any asbestos-associated disease. The prevalence of other disease processes was unrelated to asbestos exposure (arthritis, diabetes, hypertension, gout, etc.). The household contacts considered themselves to be in good health; the clinical examinations generally confirmed this. Current symptoms and clinical findings detected among the household contacts examined are summarized in Table 13. Rhonchi were the most common physical findings, not significantly associated with the prevalence of any type of radiographic abnormality. On the other hand, dyspnea, rales, cyanosis and clubbing were signifi cantly more prevalent among those with small opacities and/or pleural abnormalities on their x-rays. Table 12 Prevalence of Radiographic Abnormalities by Household Contact's Relationship to Index Worker Relationship Wives Daughter Sons Siblings Others Total Total Examined 162 224 151 81 61 679 Small Opacities 40(25%) 15 (7%) 31 (21%) 15(19%) 12(21%) 129(19%) Pleural Abnormality 58 (36%) 34(15%) 47 (31%) 22 (27%) 17 (28%) 178 (26%) Parenchymal and/or Pleural 77 (48%) 46 (21%)* 63 (42%) 30 (37%) 23 (38%) 239 (35%) Mean Duration of Exposure 2.2 2.4 yrs. 2.4 2.6 yrs. 2.3 2.8 yrs. 2.1 2.1 yrs. 3.6 3.3 yrs. Prevalence of radiographic abnormalities significantly higher among sons than daughters. X2- 19.6 pc.001.